DK3200818T3 - Fremgangsmåder til isolering af t-cellereceptorer med antigen specificitet over for en cancer-specifik mutation - Google Patents
Fremgangsmåder til isolering af t-cellereceptorer med antigen specificitet over for en cancer-specifik mutation Download PDFInfo
- Publication number
- DK3200818T3 DK3200818T3 DK14796317.7T DK14796317T DK3200818T3 DK 3200818 T3 DK3200818 T3 DK 3200818T3 DK 14796317 T DK14796317 T DK 14796317T DK 3200818 T3 DK3200818 T3 DK 3200818T3
- Authority
- DK
- Denmark
- Prior art keywords
- isolating
- cancer
- methods
- cell receptors
- antigen specificity
- Prior art date
Links
- 206010028980 Neoplasm Diseases 0.000 title 1
- 108091008874 T cell receptors Proteins 0.000 title 1
- 102000016266 T-Cell Antigen Receptors Human genes 0.000 title 1
- 239000000427 antigen Substances 0.000 title 1
- 108091007433 antigens Proteins 0.000 title 1
- 102000036639 antigens Human genes 0.000 title 1
- 201000011510 cancer Diseases 0.000 title 1
- 230000035772 mutation Effects 0.000 title 1
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- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
- C07K14/70503—Immunoglobulin superfamily
- C07K14/7051—T-cell receptor (TcR)-CD3 complex
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- A61K39/46—Cellular immunotherapy
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Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
PCT/US2014/058796 WO2016053338A1 (en) | 2014-10-02 | 2014-10-02 | Methods of isolating t cell receptors having antigenic specificity for a cancer-specific mutation |
Publications (1)
Publication Number | Publication Date |
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DK3200818T3 true DK3200818T3 (da) | 2022-08-22 |
Family
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Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DK14796317.7T DK3200818T3 (da) | 2014-10-02 | 2014-10-02 | Fremgangsmåder til isolering af t-cellereceptorer med antigen specificitet over for en cancer-specifik mutation |
Country Status (9)
Country | Link |
---|---|
US (2) | US20170218042A1 (da) |
EP (2) | EP4074333A1 (da) |
JP (1) | JP6686008B2 (da) |
CN (1) | CN107074932A (da) |
AU (3) | AU2014407539B2 (da) |
CA (1) | CA2963362A1 (da) |
DK (1) | DK3200818T3 (da) |
ES (1) | ES2924709T3 (da) |
WO (1) | WO2016053338A1 (da) |
Families Citing this family (63)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2015157636A1 (en) | 2014-04-10 | 2015-10-15 | H. Lee Moffitt Cancer Center And Research Institute, Inc. | Enhanced expansion of tumor-infiltrating lymphocytes for adoptive cell therapy |
WO2016053339A1 (en) | 2014-10-02 | 2016-04-07 | The United States Of America, As Represented By The Secretary, Department Of Health And Human Services | Methods of isolating t cells having antigenic specificity for a cancer-specific mutation |
EP3075389A1 (en) * | 2015-03-31 | 2016-10-05 | Technische Universität München | T cell receptors and peptides derived by mutations for the treatment of cancer |
US10544392B2 (en) | 2015-05-01 | 2020-01-28 | The United States Of America, As Represented By The Secretary, Department Of Health And Human Services | Methods of isolating T cells and T cell receptors having antigenic specificity for a cancer-specific mutation from peripheral blood |
JP7409773B2 (ja) | 2015-07-31 | 2024-01-09 | リージェンツ オブ ザ ユニバーシティ オブ ミネソタ | 改変された細胞および治療の方法 |
WO2017048614A1 (en) | 2015-09-15 | 2017-03-23 | The United States Of America, As Represented By The Secretary, Department Of Health And Human Services | Methods of isolating tumor-reactive t cell receptors from tumor or peripheral blood |
JP7093771B2 (ja) | 2016-07-07 | 2022-06-30 | アイオバンス バイオセラピューティクス,インコーポレイテッド | プログラム死1リガンド1(pd-l1)結合タンパク質及びその使用方法 |
EP4338799A3 (en) | 2016-10-18 | 2024-06-05 | Regents of the University of Minnesota | Tumor infiltrating lymphocytes and methods of therapy |
EP4180520A1 (en) | 2016-10-26 | 2023-05-17 | Iovance Biotherapeutics, Inc. | Restimulation of cryopreserved tumor infiltrating lymphocytes |
TWI788307B (zh) | 2016-10-31 | 2023-01-01 | 美商艾歐凡斯生物治療公司 | 用於擴增腫瘤浸潤性淋巴細胞之工程化人造抗原呈現細胞 |
JP7125392B2 (ja) | 2016-11-17 | 2022-08-24 | アイオバンス バイオセラピューティクス,インコーポレイテッド | レムナント腫瘍浸潤リンパ球並びにそれを調製及び使用する方法 |
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