DK3200818T3 - Fremgangsmåder til isolering af t-cellereceptorer med antigen specificitet over for en cancer-specifik mutation - Google Patents

Fremgangsmåder til isolering af t-cellereceptorer med antigen specificitet over for en cancer-specifik mutation Download PDF

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Publication number
DK3200818T3
DK3200818T3 DK14796317.7T DK14796317T DK3200818T3 DK 3200818 T3 DK3200818 T3 DK 3200818T3 DK 14796317 T DK14796317 T DK 14796317T DK 3200818 T3 DK3200818 T3 DK 3200818T3
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isolating
cancer
methods
cell receptors
antigen specificity
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DK14796317.7T
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Eric Tran
Paul E Robbins
Steven A Rosenberg
Yong-Chen Lu
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Us Health
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    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/70503—Immunoglobulin superfamily
    • C07K14/7051—T-cell receptor (TcR)-CD3 complex
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    • A61K40/10—Cellular immunotherapy characterised by the cell type used
    • A61K40/11—T-cells, e.g. tumour infiltrating lymphocytes [TIL] or regulatory T [Treg] cells; Lymphokine-activated killer [LAK] cells
    • A—HUMAN NECESSITIES
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    • A61K40/41—Vertebrate antigens
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DK14796317.7T 2014-10-02 2014-10-02 Fremgangsmåder til isolering af t-cellereceptorer med antigen specificitet over for en cancer-specifik mutation DK3200818T3 (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PCT/US2014/058796 WO2016053338A1 (en) 2014-10-02 2014-10-02 Methods of isolating t cell receptors having antigenic specificity for a cancer-specific mutation

Publications (1)

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DK3200818T3 true DK3200818T3 (da) 2022-08-22

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US (2) US20170218042A1 (enExample)
EP (2) EP3200818B1 (enExample)
JP (1) JP6686008B2 (enExample)
CN (2) CN107074932A (enExample)
AU (3) AU2014407539B2 (enExample)
CA (1) CA2963362A1 (enExample)
DK (1) DK3200818T3 (enExample)
ES (1) ES2924709T3 (enExample)
WO (1) WO2016053338A1 (enExample)

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ES2980788T3 (es) 2014-04-10 2024-10-03 H Lee Moffitt Cancer Ct & Res Expansión mejorada de linfocitos infiltrantes de tumores para terapia celular adoptiva
CN107075479A (zh) 2014-10-02 2017-08-18 美国卫生和人力服务部 分离对癌症特异性突变具有抗原特异性的t细胞的方法
EP3075389A1 (en) * 2015-03-31 2016-10-05 Technische Universität München T cell receptors and peptides derived by mutations for the treatment of cancer
US10544392B2 (en) 2015-05-01 2020-01-28 The United States Of America, As Represented By The Secretary, Department Of Health And Human Services Methods of isolating T cells and T cell receptors having antigenic specificity for a cancer-specific mutation from peripheral blood
EP4339287A3 (en) 2015-07-31 2024-05-22 Regents Of The University Of Minnesota Modified cells and methods of therapy
WO2017048614A1 (en) 2015-09-15 2017-03-23 The United States Of America, As Represented By The Secretary, Department Of Health And Human Services Methods of isolating tumor-reactive t cell receptors from tumor or peripheral blood
US11141434B2 (en) 2016-07-07 2021-10-12 Iovance Biotherapeutics, Inc. Programmed death 1 ligand 1 (PD-L1) binding proteins and methods of use thereof
EP4338799A3 (en) 2016-10-18 2024-06-05 Regents of the University of Minnesota Tumor infiltrating lymphocytes and methods of therapy
CN110099998A (zh) 2016-10-26 2019-08-06 艾欧凡斯生物治疗公司 冷冻保存的肿瘤浸润淋巴细胞的再刺激
TWI788307B (zh) 2016-10-31 2023-01-01 美商艾歐凡斯生物治療公司 用於擴增腫瘤浸潤性淋巴細胞之工程化人造抗原呈現細胞
TWI826360B (zh) 2016-11-17 2023-12-21 美商艾歐凡斯生物治療公司 殘餘腫瘤浸潤性淋巴細胞及製備和使用彼之方法
ES3055314T3 (en) 2017-01-06 2026-02-11 Iovance Biotherapeutics Inc Expansion of tumor infiltrating lymphocytes with potassium channel agonists and therapeutic uses thereof
JOP20190224A1 (ar) 2017-03-29 2019-09-26 Iovance Biotherapeutics Inc عمليات من أجل إنتاج الخلايا اللمفاوية المرتشحة للأورام واستخداماتها في العلاج المناعي
US11254913B1 (en) 2017-03-29 2022-02-22 Iovance Biotherapeutics, Inc. Processes for production of tumor infiltrating lymphocytes and uses of same in immunotherapy
EP3602053B1 (en) * 2017-03-31 2023-06-28 The United States of America, as represented by The Secretary, Department of Health and Human Services Methods of isolating neoantigen-specific t cell receptor sequences
KR102920712B1 (ko) 2017-05-24 2026-01-30 노파르티스 아게 항체-사이토카인 생착된 단백질 및 암 치료에 있어서의 사용 방법
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