JP6612232B2 - 対象のマルチキナーゼ阻害剤に対する応答性を予測する遺伝子発現シグネチャ、及びその使用 - Google Patents

対象のマルチキナーゼ阻害剤に対する応答性を予測する遺伝子発現シグネチャ、及びその使用 Download PDF

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JP6612232B2
JP6612232B2 JP2016537848A JP2016537848A JP6612232B2 JP 6612232 B2 JP6612232 B2 JP 6612232B2 JP 2016537848 A JP2016537848 A JP 2016537848A JP 2016537848 A JP2016537848 A JP 2016537848A JP 6612232 B2 JP6612232 B2 JP 6612232B2
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シェン クオ
ダウェイ チェン
チュアン チャン
チエ カイ
ヘンリー キシャン リ
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クラウン バイオサイエンス インコーポレイテッド（タイカン）
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    • C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
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    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
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    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
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    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/106—Pharmacogenomics, i.e. genetic variability in individual responses to drugs and drug metabolism
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    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/158—Expression markers

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  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
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JP2016537848A 2013-08-28 2014-08-28 対象のマルチキナーゼ阻害剤に対する応答性を予測する遺伝子発現シグネチャ、及びその使用 Active JP6612232B2 (ja)

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CN2013082487 2013-08-28
CNPCT/CN2013/082487 2013-08-28
PCT/US2014/053142 WO2015031604A1 (en) 2013-08-28 2014-08-28 Gene expression signatures predictive of subject response to a multi-kinase inhibitor and methods of using the same

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JP2016528914A JP2016528914A (ja) 2016-09-23
JP2016528914A5 JP2016528914A5 (https=) 2017-09-28
JP6612232B2 true JP6612232B2 (ja) 2019-11-27

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US (1) US11136625B2 (https=)
EP (1) EP3039424B1 (https=)
JP (1) JP6612232B2 (https=)
CN (1) CN105659085B (https=)
CY (1) CY1123415T1 (https=)
DK (1) DK3039424T3 (https=)
ES (1) ES2813877T3 (https=)
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WO2020085936A1 (ru) * 2018-10-24 2020-04-30 Общество С Ограниченной Ответственностью "Онкобокс" Тест-классификатор клинического ответа на лечение сорафенибом индивидуальных пациентов с раком почки
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CN111521810B (zh) * 2019-02-02 2024-06-21 中国科学院上海药物研究所 癌症患者根据脾酪氨酸激酶进行分层
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US11136625B2 (en) 2021-10-05
ES2813877T3 (es) 2021-03-25
PT3039424T (pt) 2020-09-03
US20160208328A1 (en) 2016-07-21
EP3039424A1 (en) 2016-07-06
CN105659085A (zh) 2016-06-08
JP2016528914A (ja) 2016-09-23
WO2015031604A1 (en) 2015-03-05
EP3039424A4 (en) 2017-03-29
CN105659085B (zh) 2018-12-07
EP3039424B1 (en) 2020-07-29
CY1123415T1 (el) 2021-12-31
DK3039424T3 (da) 2020-08-31

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