JP6553605B2 - 血管新生抑制活性を有するペプチド、及びそれを含む組成物 - Google Patents
血管新生抑制活性を有するペプチド、及びそれを含む組成物 Download PDFInfo
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- JP6553605B2 JP6553605B2 JP2016533182A JP2016533182A JP6553605B2 JP 6553605 B2 JP6553605 B2 JP 6553605B2 JP 2016533182 A JP2016533182 A JP 2016533182A JP 2016533182 A JP2016533182 A JP 2016533182A JP 6553605 B2 JP6553605 B2 JP 6553605B2
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/43—Enzymes; Proenzymes; Derivatives thereof
- A61K38/45—Transferases (2)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
- A61K38/08—Peptides having 5 to 11 amino acids
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- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
- A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
- A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
- A23L33/17—Amino acids, peptides or proteins
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- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
- A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
- A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
- A23L33/17—Amino acids, peptides or proteins
- A23L33/18—Peptides; Protein hydrolysates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
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- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
-
- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/12—Drugs for disorders of the urinary system of the kidneys
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- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
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- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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- A61P17/06—Antipsoriatics
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- A—HUMAN NECESSITIES
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- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
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- A—HUMAN NECESSITIES
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- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
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- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
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- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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- A61P9/00—Drugs for disorders of the cardiovascular system
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/10—Transferases (2.)
- C12N9/12—Transferases (2.) transferring phosphorus containing groups, e.g. kinases (2.7)
- C12N9/1241—Nucleotidyltransferases (2.7.7)
- C12N9/1276—RNA-directed DNA polymerase (2.7.7.49), i.e. reverse transcriptase or telomerase
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Y—ENZYMES
- C12Y207/00—Transferases transferring phosphorus-containing groups (2.7)
- C12Y207/07—Nucleotidyltransferases (2.7.7)
- C12Y207/07049—RNA-directed DNA polymerase (2.7.7.49), i.e. telomerase or reverse-transcriptase
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
- A23V2002/00—Food compositions, function of food ingredients or processes for food or foodstuffs
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Immunology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Zoology (AREA)
- Genetics & Genomics (AREA)
- Wood Science & Technology (AREA)
- Molecular Biology (AREA)
- Gastroenterology & Hepatology (AREA)
- Biomedical Technology (AREA)
- Epidemiology (AREA)
- Biochemistry (AREA)
- General Engineering & Computer Science (AREA)
- Diabetes (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Urology & Nephrology (AREA)
- Dermatology (AREA)
- Ophthalmology & Optometry (AREA)
- Food Science & Technology (AREA)
- Polymers & Plastics (AREA)
- Nutrition Science (AREA)
- Mycology (AREA)
- Microbiology (AREA)
- Biotechnology (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| KR10-2013-0142897 | 2013-11-22 | ||
| KR20130142897 | 2013-11-22 | ||
| KR10-2014-0020605 | 2014-02-21 | ||
| KR20140020605 | 2014-02-21 | ||
| PCT/KR2014/011280 WO2015076621A1 (ko) | 2013-11-22 | 2014-11-21 | 혈관 신생 억제 활성을 가지는 펩티드 및 이를 포함하는 조성물 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2016539121A JP2016539121A (ja) | 2016-12-15 |
| JP2016539121A5 JP2016539121A5 (cg-RX-API-DMAC7.html) | 2018-01-11 |
| JP6553605B2 true JP6553605B2 (ja) | 2019-07-31 |
Family
ID=53179816
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2016533182A Active JP6553605B2 (ja) | 2013-11-22 | 2014-11-21 | 血管新生抑制活性を有するペプチド、及びそれを含む組成物 |
Country Status (7)
| Country | Link |
|---|---|
| US (1) | US10034922B2 (cg-RX-API-DMAC7.html) |
| EP (1) | EP3072519B1 (cg-RX-API-DMAC7.html) |
| JP (1) | JP6553605B2 (cg-RX-API-DMAC7.html) |
| KR (3) | KR102494803B1 (cg-RX-API-DMAC7.html) |
| CN (1) | CN105848667B (cg-RX-API-DMAC7.html) |
| ES (1) | ES2818921T3 (cg-RX-API-DMAC7.html) |
| WO (1) | WO2015076621A1 (cg-RX-API-DMAC7.html) |
Families Citing this family (21)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP6267190B2 (ja) | 2012-05-11 | 2018-01-24 | ジェムバックス アンド カエル カンパニー,リミティド | 悪液質の予防用または治療用組成物 |
| ES3046661T3 (en) | 2012-05-11 | 2025-12-02 | Gemvax & Kael Co Ltd | Anti-inflammatory peptides and composition comprising the same |
| JP6272853B2 (ja) | 2012-07-11 | 2018-01-31 | ジェムバックス アンド カエル カンパニー,リミティド | 細胞透過性ペプチド、それを含んだコンジュゲート、及びそれを含んだ組成物 |
| KR102258864B1 (ko) | 2013-04-19 | 2021-06-01 | 주식회사 젬백스앤카엘 | 허혈성 손상 치료 및 예방용 조성물 |
| EP3004883B1 (en) | 2013-06-07 | 2022-09-14 | Gemvax & Kael Co., Ltd. | Gv1001, gemcitabine and capecitabine for use in the treatment of pancreatic cancer in high eotaxin baseline level patients |
| JP6495899B2 (ja) | 2013-06-21 | 2019-04-03 | ジェムバックス アンド カエル カンパニー,リミティド | ホルモン分泌調節剤、及びそれを含む組成物 |
| EP3085380B1 (en) | 2013-12-17 | 2020-06-17 | Gemvax & Kael Co., Ltd. | Composition for treating prostate cancer |
| US10632349B2 (en) | 2017-11-03 | 2020-04-28 | Parsons Xtreme Golf, LLC | Golf club heads and methods to manufacture golf club heads |
| ES2908096T3 (es) | 2014-04-11 | 2022-04-27 | Gemvax & Kael Co Ltd | Péptido con actividad inhibidora de la fibrosis y composición que lo contiene |
| CN106659149B (zh) | 2014-04-30 | 2020-05-19 | 珍白斯凯尔有限公司 | 用于器官、组织或细胞移植的组合物、试剂盒和移植方法 |
| KR102413243B1 (ko) | 2014-12-23 | 2022-06-27 | 주식회사 젬백스앤카엘 | 안질환 치료 펩티드 및 이를 포함하는 안질환 치료용 조성물 |
| JP6751097B2 (ja) | 2015-02-27 | 2020-09-02 | ジェムバックス アンド カエル カンパニー,リミティド | 聴力損傷予防用ペプチド及びそれを含む組成物 |
| US11015179B2 (en) | 2015-07-02 | 2021-05-25 | Gemvax & Kael Co., Ltd. | Peptide having anti-viral effect and composition containing same |
| EP4272829A3 (en) | 2016-04-07 | 2024-01-17 | Gemvax & Kael Co., Ltd. | Peptide having effects of increasing telomerase activity and extending telomere, and composition containing same |
| JP7107968B2 (ja) * | 2017-01-13 | 2022-07-27 | ヴァゾミューン セラピューティクス インコーポレイテッド | 血管新生を促進する薬剤ならびにその方法および使用 |
| CN108421050A (zh) * | 2017-02-15 | 2018-08-21 | 闵晓洁 | 小分子rna干扰端粒酶逆转录酶质粒抑制视网膜、脉络膜新生血管新制剂 |
| KR101998155B1 (ko) | 2017-09-22 | 2019-07-10 | (주)케어젠 | 혈관신생 억제용 펩타이드 및 이의 용도 |
| EP3849583B1 (en) * | 2018-09-11 | 2025-12-31 | Anbition S.r.l. | PEPTIDES FOR THE TREATMENT OF NEOVASCULAR EYE DISEASES |
| KR102467670B1 (ko) * | 2022-05-16 | 2022-11-17 | 줄리아 연구소 주식회사 | Shc1 단백질 또는 항-shc1 항체를 포함하는 혈관신생성 질환의 예방, 치료 또는 개선용 약학적 조성물 및 건강기능식품 조성물 |
| KR102587729B1 (ko) * | 2023-02-27 | 2023-10-12 | 주식회사 아이바이오코리아 | 펩타이드를 포함하는 당뇨망막병증의 치료용 조성물 |
| CN121001732A (zh) * | 2023-05-17 | 2025-11-21 | 珍白斯凯尔有限公司 | 包含gv1001的用于预防或治疗黄斑变性的组合物 |
Family Cites Families (76)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR930001915B1 (ko) | 1990-06-27 | 1993-03-20 | 포항종합제철 주식회사 | 저온 소결 압전요업재료 제조방법 |
| WO1998003180A2 (en) | 1996-07-22 | 1998-01-29 | The Victoria University Of Manchester | Use of sex steroids function modulators to treat wounds and fibrotic disorders |
| US6610839B1 (en) * | 1997-08-14 | 2003-08-26 | Geron Corporation | Promoter for telomerase reverse transcriptase |
| DE69837707T2 (de) | 1997-05-15 | 2008-01-10 | Chugai Seiyaku K.K. | Heilmittel für kachexie |
| CA2294782A1 (en) | 1997-07-01 | 1999-01-14 | Cambia Biosystems Llc | Vertebrate telomerase genes and proteins and uses thereof |
| US7030211B1 (en) * | 1998-07-08 | 2006-04-18 | Gemvax As | Antigenic peptides derived from telomerase |
| US6378526B1 (en) | 1998-08-03 | 2002-04-30 | Insite Vision, Incorporated | Methods of ophthalmic administration |
| IL132406A0 (en) | 1998-10-21 | 2001-03-19 | Pfizer Prod Inc | Treatment of bph with cgmp elevators |
| CN1264858C (zh) * | 2001-02-16 | 2006-07-19 | 纳幕尔杜邦公司 | 血管生成抑制三肽、组合物及其使用方法 |
| US6815426B2 (en) | 2001-02-16 | 2004-11-09 | E. I. Du Pont De Nemours And Company | Angiogenesis-inhibitory tripeptides, compositions and their methods of use |
| EP1378237A4 (en) | 2001-04-10 | 2009-03-25 | Nippon Shinyaku Co Ltd | THERAPEUTIC AGENT FOR CHRONIC JOINT RHEUMATISM |
| UA85531C2 (uk) | 2001-05-16 | 2009-02-10 | Йеда Рисерч Энд Дивелопмент Ко. Лтд. | Застосування il-18 інгібіторів для лікування або попередження пов'язаної з сепсисом дисфункції серця |
| AU2002363231A1 (en) * | 2001-10-29 | 2003-05-12 | Baylor College Of Medicine | Human telomerase reverse transcriptase as a class-ii restricted tumor-associated antigen |
| US7786084B2 (en) | 2001-12-21 | 2010-08-31 | Biotempt B.V. | Treatment of burns |
| CA2480084A1 (en) | 2002-04-10 | 2003-10-16 | Applied Research Systems Ars Holding N.V. | Use of osteoprotegerin for the prevention and/or treatment of fibrosis/sclerosis |
| KR20050020987A (ko) | 2002-06-12 | 2005-03-04 | 바이오겐 아이덱 엠에이 인코포레이티드 | 아데노신 수용체 길항제를 사용하여 허혈 재관류 손상을치료하는 방법 |
| WO2004112820A2 (en) | 2003-06-25 | 2004-12-29 | Canbas Co., Ltd. | Peptides and peptidomimetics having immune-modulating, anti-inflammatory, and anti-viral activity |
| KR20050040517A (ko) | 2003-10-29 | 2005-05-03 | 주식회사 오리엔트 | 허혈성 질환에 대한 저항성을 나타내는 형질전환 생쥐 |
| ATE319426T1 (de) | 2003-11-11 | 2006-03-15 | Mattern Udo | Nasenformulierung mit kontrollierter freisetzung von sexualhormonen |
| GB0426146D0 (en) | 2004-11-29 | 2004-12-29 | Bioxell Spa | Therapeutic peptides and method |
| EP2374508A1 (en) | 2005-03-21 | 2011-10-12 | Vicus Therapeutics SPE 1, LLC | Combination of angiotension receptor blockers (ARB) and NSAIDs for use in ameliorating cachexia |
| US20090269335A1 (en) | 2005-11-25 | 2009-10-29 | Keio University | Therapeutic agent for prostate cancer |
| EP1968643A2 (en) | 2005-12-16 | 2008-09-17 | Diatos | Cell penetrating peptide conjugates for delivering of nucleic acids into a cell |
| JP5295785B2 (ja) | 2006-02-20 | 2013-09-18 | エファ・ユニバーシティ・インダストリー・コラボレイション・ファウンデイション | 細胞膜透過性ペプチド |
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2014
- 2014-11-21 KR KR1020227003326A patent/KR102494803B1/ko active Active
- 2014-11-21 EP EP14864515.3A patent/EP3072519B1/en active Active
- 2014-11-21 WO PCT/KR2014/011280 patent/WO2015076621A1/ko not_active Ceased
- 2014-11-21 CN CN201480070167.3A patent/CN105848667B/zh active Active
- 2014-11-21 KR KR1020167015069A patent/KR102359396B1/ko active Active
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Also Published As
| Publication number | Publication date |
|---|---|
| KR102494803B1 (ko) | 2023-02-06 |
| EP3072519A1 (en) | 2016-09-28 |
| KR102359396B1 (ko) | 2022-02-08 |
| CN105848667A (zh) | 2016-08-10 |
| KR20160079881A (ko) | 2016-07-06 |
| KR20230020009A (ko) | 2023-02-09 |
| EP3072519B1 (en) | 2020-08-19 |
| CN105848667B (zh) | 2020-05-19 |
| KR102694658B1 (ko) | 2024-08-14 |
| EP3072519A4 (en) | 2017-04-19 |
| JP2016539121A (ja) | 2016-12-15 |
| KR20220020411A (ko) | 2022-02-18 |
| US10034922B2 (en) | 2018-07-31 |
| ES2818921T3 (es) | 2021-04-14 |
| WO2015076621A1 (ko) | 2015-05-28 |
| US20160296604A1 (en) | 2016-10-13 |
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