JP6527851B2 - ロイコトリエンa4加水分解酵素を阻害する方法 - Google Patents
ロイコトリエンa4加水分解酵素を阻害する方法 Download PDFInfo
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- JP6527851B2 JP6527851B2 JP2016501158A JP2016501158A JP6527851B2 JP 6527851 B2 JP6527851 B2 JP 6527851B2 JP 2016501158 A JP2016501158 A JP 2016501158A JP 2016501158 A JP2016501158 A JP 2016501158A JP 6527851 B2 JP6527851 B2 JP 6527851B2
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- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
- A61K31/551—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole having two nitrogen atoms, e.g. dilazep
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- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
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Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201361776981P | 2013-03-12 | 2013-03-12 | |
| US61/776,981 | 2013-03-12 | ||
| PCT/US2014/023138 WO2014164658A1 (en) | 2013-03-12 | 2014-03-11 | Methods of inhibiting leukotriene a4 hydrolase |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2016512517A JP2016512517A (ja) | 2016-04-28 |
| JP2016512517A5 JP2016512517A5 (enExample) | 2017-04-13 |
| JP6527851B2 true JP6527851B2 (ja) | 2019-06-05 |
Family
ID=51658933
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2016501158A Active JP6527851B2 (ja) | 2013-03-12 | 2014-03-11 | ロイコトリエンa4加水分解酵素を阻害する方法 |
Country Status (8)
| Country | Link |
|---|---|
| US (3) | US9820974B2 (enExample) |
| EP (1) | EP2968359B1 (enExample) |
| JP (1) | JP6527851B2 (enExample) |
| AU (1) | AU2014249168B2 (enExample) |
| CA (1) | CA2905340C (enExample) |
| ES (1) | ES2864862T3 (enExample) |
| RU (1) | RU2686101C2 (enExample) |
| WO (1) | WO2014164658A1 (enExample) |
Families Citing this family (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DK1976828T3 (en) | 2005-12-29 | 2017-03-06 | Celtaxsys Inc | DIAMINE DERIVATIVES AS INhibitors of Leukotriene A4 HYDROLASE |
| JP6527851B2 (ja) | 2013-03-12 | 2019-06-05 | セルタクシス,インコーポレイテッド | ロイコトリエンa4加水分解酵素を阻害する方法 |
| MX2015011676A (es) | 2013-03-14 | 2016-04-25 | Celtaxsys Inc | Inhibidores de leucotrieno a4 hidrolasa. |
| EP2970309A4 (en) | 2013-03-14 | 2016-11-09 | Celtaxsys Inc | INHIBITORS OF LEUCOTRIENE A4 HYDROLASE |
| MX2015011677A (es) * | 2013-03-14 | 2016-07-08 | Celtaxsys Inc | Inhibidores de leucotrieno a4 hidrolasa. |
| CA3097083A1 (en) * | 2018-05-15 | 2019-11-21 | Alkahest, Inc. | Treatment of aging-associated disease with modulators of leukotriene a4 hydrolase |
| AU2019278935B2 (en) * | 2018-05-31 | 2025-02-13 | Celltaxis, Llc | Method of reducing pulmonary exacerbations in respiratory disease patients |
| ES2998786T3 (en) | 2019-01-11 | 2025-02-21 | Novartis Ag | Lta4h inhibitor for the treatment or prevention of hidradenitis suppurativa |
| TW202122078A (zh) | 2019-09-06 | 2021-06-16 | 瑞士商諾華公司 | 使用lta4h抑制劑治療肝臟疾病之方法 |
| AU2021325431B2 (en) | 2020-08-14 | 2024-01-18 | Novartis Ag | Heteroaryl substituted spiropiperidinyl derivatives and pharmaceutical uses thereof |
| CA3221177A1 (en) | 2021-11-01 | 2023-05-04 | Meghan Kerrisk Campbell | Benzodioxane modulators of leukotriene a4 hydrolase (lta4h) for prevention and treatment of aging-associated diseases |
| EP4444419A4 (en) * | 2021-12-09 | 2025-10-01 | Celltaxis Llc | METHODS OF TREATING LYMPHOEDEMA |
| WO2024254377A2 (en) * | 2023-06-09 | 2024-12-12 | Celltaxis, Llc | Methods of treating lipedema and lymphatic disease of the subcutaneous tissue |
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| EP2968359A4 (en) | 2016-11-23 |
| US20160067226A1 (en) | 2016-03-10 |
| EP2968359B1 (en) | 2021-01-20 |
| ES2864862T3 (es) | 2021-10-14 |
| RU2015137978A3 (enExample) | 2018-03-21 |
| US20200138791A1 (en) | 2020-05-07 |
| WO2014164658A1 (en) | 2014-10-09 |
| US10898471B2 (en) | 2021-01-26 |
| RU2686101C2 (ru) | 2019-04-24 |
| CA2905340C (en) | 2022-05-31 |
| CA2905340A1 (en) | 2014-10-09 |
| AU2014249168A1 (en) | 2015-10-01 |
| US9820974B2 (en) | 2017-11-21 |
| US20180117014A1 (en) | 2018-05-03 |
| EP2968359A1 (en) | 2016-01-20 |
| US10350197B2 (en) | 2019-07-16 |
| JP2016512517A (ja) | 2016-04-28 |
| AU2014249168B2 (en) | 2018-07-12 |
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