JP6494507B2 - グリピカン−３に対する高親和性モノクローナル抗体およびその使用 - Google Patents

グリピカン−３に対する高親和性モノクローナル抗体およびその使用 Download PDF

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JP6494507B2
JP6494507B2 JP2015515243A JP2015515243A JP6494507B2 JP 6494507 B2 JP6494507 B2 JP 6494507B2 JP 2015515243 A JP2015515243 A JP 2015515243A JP 2015515243 A JP2015515243 A JP 2015515243A JP 6494507 B2 JP6494507 B2 JP 6494507B2
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antibody
amino acid
gpc3
heavy chain
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JP2015526387A (ja
JP2015526387A5 (https=
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ミッチェル ホー，
ミッチェル ホー，
イェン ティー． フォン，
イェン ティー． フォン，
ウェイ ガオ，
ウェイ ガオ，
イーファン ジャン，
イーファン ジャン，
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US Department of Health and Human Services
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JP2015515243A 2012-06-01 2013-05-31 グリピカン−３に対する高親和性モノクローナル抗体およびその使用 Active JP6494507B2 (ja)

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US201261654232P 2012-06-01 2012-06-01
US61/654,232 2012-06-01
PCT/US2013/043633 WO2013181543A1 (en) 2012-06-01 2013-05-31 High-affinity monoclonal antibodies to glypican-3 and use thereof

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KR (1) KR102159773B1 (https=)
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EP3050963B1 (en) 2005-03-31 2019-09-18 Chugai Seiyaku Kabushiki Kaisha Process for production of polypeptide by regulation of assembly
ES2892925T3 (es) 2006-03-31 2022-02-07 Chugai Pharmaceutical Co Ltd Métodos para controlar la farmacocinética en sangre de anticuerpos
CN101874042B9 (zh) 2007-09-26 2019-01-01 中外制药株式会社 利用cdr的氨基酸取代来改变抗体等电点的方法
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