JP6466832B2 - Ｓｅｒｐｉｎｃ１ｉＲＮＡ組成物およびその使用方法 - Google Patents

Ｓｅｒｐｉｎｃ１ｉＲＮＡ組成物およびその使用方法 Download PDF

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JP6466832B2
JP6466832B2 JP2015509141A JP2015509141A JP6466832B2 JP 6466832 B2 JP6466832 B2 JP 6466832B2 JP 2015509141 A JP2015509141 A JP 2015509141A JP 2015509141 A JP2015509141 A JP 2015509141A JP 6466832 B2 JP6466832 B2 JP 6466832B2
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dsrna
dsrna agent
subject
sense strand
seq
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JP2015519047A (ja
JP2015519047A5 (ru
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アキン・アキンク
アルフィカ・セーガル
イバンカ・トウジャースカ
ドナルド・フォスター
スチュアート・ミルスタイン
ブライアン・ベッテンコート
マルティン・マイアー
クラウス・カリセ
サティアナラヤーナ・クチマンチ
カラントッタティル・ジー・ラジーブ
ムティア・マノハラン
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Genzyme Corp
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Genzyme Corp
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    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/113—Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • C12N2320/00—Applications; Uses
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  • Health & Medical Sciences (AREA)
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  • Biomedical Technology (AREA)
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  • Wood Science & Technology (AREA)
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  • Animal Behavior & Ethology (AREA)
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  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
JP2015509141A 2012-04-26 2013-04-25 Ｓｅｒｐｉｎｃ１ｉＲＮＡ組成物およびその使用方法 Active JP6466832B2 (ja)

Priority Applications (1)

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JP2019002713A JP6933670B2 (ja) 2012-04-26 2019-01-10 Ｓｅｒｐｉｎｃ１ ｉＲＮＡ組成物およびその使用方法

Applications Claiming Priority (9)

Application Number Priority Date Filing Date Title
US201261638952P 2012-04-26 2012-04-26
US61/638,952 2012-04-26
US201261669249P 2012-07-09 2012-07-09
US61/669,249 2012-07-09
US201261734573P 2012-12-07 2012-12-07
US61/734,573 2012-12-07
US13/837,129 2013-03-15
US13/837,129 US9127274B2 (en) 2012-04-26 2013-03-15 Serpinc1 iRNA compositions and methods of use thereof
PCT/US2013/038218 WO2013163430A2 (en) 2012-04-26 2013-04-25 Serpinc1 irna compositions and methods of use thereof

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JP2015519047A JP2015519047A (ja) 2015-07-09
JP2015519047A5 JP2015519047A5 (ru) 2016-06-16
JP6466832B2 true JP6466832B2 (ja) 2019-02-06

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JP2019002713A Active JP6933670B2 (ja) 2012-04-26 2019-01-10 Ｓｅｒｐｉｎｃ１ ｉＲＮＡ組成物およびその使用方法
JP2021134158A Active JP7478121B2 (ja) 2012-04-26 2021-08-19 Ｓｅｒｐｉｎｃ１ ｉＲＮＡ組成物およびその使用方法
JP2024068113A Pending JP2024099663A (ja) 2012-04-26 2024-04-19 Ｓｅｒｐｉｎｃ１ ｉＲＮＡ組成物およびその使用方法

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JP2021134158A Active JP7478121B2 (ja) 2012-04-26 2021-08-19 Ｓｅｒｐｉｎｃ１ ｉＲＮＡ組成物およびその使用方法
JP2024068113A Pending JP2024099663A (ja) 2012-04-26 2024-04-19 Ｓｅｒｐｉｎｃ１ ｉＲＮＡ組成物およびその使用方法

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US (6) US9127274B2 (ru)
EP (2) EP2841443B1 (ru)
JP (4) JP6466832B2 (ru)
KR (4) KR102254380B1 (ru)
CN (4) CN110295167A (ru)
AR (1) AR090869A1 (ru)
AU (4) AU2013251494A1 (ru)
BR (1) BR112014026758A2 (ru)
CA (1) CA2869922A1 (ru)
CL (1) CL2016000188A1 (ru)
CO (1) CO7240361A2 (ru)
ES (1) ES2934152T3 (ru)
FI (1) FI2841443T3 (ru)
HK (1) HK1204336A1 (ru)
HR (1) HRP20221498T1 (ru)
HU (1) HUE060846T2 (ru)
IL (4) IL234941B (ru)
LT (1) LT2841443T (ru)
MX (2) MX365419B (ru)
PL (1) PL2841443T3 (ru)
PT (1) PT2841443T (ru)
RS (1) RS63838B1 (ru)
RU (2) RU2691580C2 (ru)
SI (1) SI2841443T1 (ru)
WO (1) WO2013163430A2 (ru)

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