WO1998017815A1
(en)
*
|
1996-10-17 |
1998-04-30 |
Oxford Biomedica (Uk) Limited |
Retroviral vectors
|
US7198784B2
(en)
|
1996-10-17 |
2007-04-03 |
Oxford Biomedica (Uk) Limited |
Retroviral vectors
|
US6933378B2
(en)
|
1997-05-30 |
2005-08-23 |
Joseph Atabekov |
Methods for coexpression of more than one gene in eukaryotic cells
|
FI972293A
(fi)
|
1997-05-30 |
1998-12-01 |
Joseph Atabekov |
Useamman kuin yhden geenin yhteisekspressiomenetelmät
|
US7276488B2
(en)
*
|
1997-06-04 |
2007-10-02 |
Oxford Biomedica (Uk) Limited |
Vector system
|
CN1224712C
(zh)
*
|
1997-06-04 |
2005-10-26 |
牛津生物医学(英国)有限公司 |
载体
|
US7635687B2
(en)
*
|
1997-06-04 |
2009-12-22 |
Oxford Biomedica (Uk) Limited |
Vector system
|
WO1999014353A2
(en)
*
|
1997-09-19 |
1999-03-25 |
Dana-Farber Cancer Institute, Inc. |
Intrabody-mediated control of immune reactions
|
ATE452982T1
(de)
*
|
1998-07-10 |
2010-01-15 |
Univ Paris Curie |
Verfahren zur verabreichng von nukleinsäuren in zellen in vitro oder ex vivo
|
US6333396B1
(en)
*
|
1998-10-20 |
2001-12-25 |
Enzon, Inc. |
Method for targeted delivery of nucleic acids
|
JP2003501111A
(ja)
*
|
1999-06-11 |
2003-01-14 |
ニューロビール セラピューティクス インコーポレーティッド |
ウイルスベクターと荷電分子の遺伝子治療への利用
|
FR2810048A1
(fr)
*
|
2000-06-07 |
2001-12-14 |
Centre Nat Rech Scient |
Construction d'acide nucleique utile pour l'expression de transgenes notamment dans les cellules souches embryonnaires
|
GB0024550D0
(de)
|
2000-10-06 |
2000-11-22 |
Oxford Biomedica Ltd |
|
WO2002086096A2
(en)
*
|
2001-01-23 |
2002-10-31 |
University Of Rochester Medical Center |
Methods of producing or identifying intrabodies in eukaryotic cells
|
GB0126378D0
(en)
*
|
2001-11-02 |
2002-01-02 |
Oxford Biomedica Ltd |
Antigen
|
WO2003048306A2
(en)
|
2001-11-16 |
2003-06-12 |
Idec Pharmaceuticals Corporation |
Polycistronic expression of antibodies
|
US20030157641A1
(en)
*
|
2001-11-16 |
2003-08-21 |
Idec Pharmaceuticals Corporation |
Polycistronic expression of antibodies
|
JP4598398B2
(ja)
*
|
2002-02-01 |
2010-12-15 |
オックスフォード バイオメディカ (ユーケー) リミテッド |
ウイルスベクター
|
US9738907B2
(en)
|
2002-02-01 |
2017-08-22 |
Oxford Biomedica (Uk) Limited |
Viral vector
|
WO2006022944A2
(en)
|
2004-07-21 |
2006-03-02 |
Dana-Farber Cancer Institute, Inc. |
Lentiviral vectors and uses thereof
|
WO2006119137A1
(en)
*
|
2005-04-29 |
2006-11-09 |
The University Of North Carolina At Chapel Hill |
Methods and compositions for regulated expression of nucleic acid at post-transcriptional level
|
US8895002B2
(en)
|
2007-04-09 |
2014-11-25 |
The General Hospital Corporation |
Hemojuvelin fusion proteins and uses thereof
|
US20110038935A1
(en)
|
2007-12-06 |
2011-02-17 |
Marasco Wayne A |
Antibodies against influenza virus and methods of use thereof
|
RU2476597C2
(ru)
*
|
2009-06-16 |
2013-02-27 |
Федеральное государственное бюджетное учреждение науки Институт биологии гена Российской академии наук (ИБГ РАН) |
Способ идентификации элементов, обладающих способностью терминировать транскрипты
|
CN105031618A
(zh)
|
2009-11-02 |
2015-11-11 |
加利福尼亚大学董事会 |
用于细胞因子递送的穹窿体复合物
|
US8551781B2
(en)
|
2009-11-19 |
2013-10-08 |
The Regents Of The University Of California |
Vault complexes for facilitating biomolecule delivery
|
EP4385568A2
(de)
|
2010-04-06 |
2024-06-19 |
Alnylam Pharmaceuticals, Inc. |
Zusammensetzungen und verfahren zur hemmung der cd274/pd-l1-genexpression
|
CA2801066C
(en)
|
2010-06-02 |
2021-02-09 |
Alnylam Pharmaceuticals, Inc. |
Compositions and methods directed to treating liver fibrosis
|
JP2014504184A
(ja)
|
2010-12-01 |
2014-02-20 |
スパイナル・モデュレーション・インコーポレイテッド |
神経構造への薬剤の直接送達
|
EP2648763A4
(de)
|
2010-12-10 |
2014-05-14 |
Alnylam Pharmaceuticals Inc |
Zusammensetzungen und verfahren zur expressionshemmung der gene klf-1 und bcl11a
|
US9193973B2
(en)
|
2010-12-10 |
2015-11-24 |
Alynylam Pharmaceuticals, Inc. |
Compositions and methods for increasing erythropoietin (EPO) production
|
US9428565B2
(en)
|
2011-01-31 |
2016-08-30 |
The General Hospital Corporation |
Treatment and bioluminescent visualization using multimodal TRAIL molecules
|
KR102481317B1
(ko)
|
2011-03-29 |
2022-12-26 |
알닐람 파마슈티칼스 인코포레이티드 |
Tmprss6 유전자의 발현을 억제하기 위한 조성물 및 방법
|
US20140275211A1
(en)
|
2011-06-21 |
2014-09-18 |
Alnylam Pharmaceuticals, Inc. |
Assays and methods for determining activity of a therapeutic agent in a subject
|
ES2923573T3
(es)
|
2011-06-21 |
2022-09-28 |
Alnylam Pharmaceuticals Inc |
Composiciones de ARNi de proteína 3 de tipo angiopoyetina (ANGPTL3) y métodos de uso de las mismas
|
WO2012178033A2
(en)
|
2011-06-23 |
2012-12-27 |
Alnylam Pharmaceuticals, Inc. |
Serpina1 sirnas: compositions of matter and methods of treatment
|
EP2739735A2
(de)
|
2011-08-01 |
2014-06-11 |
Alnylam Pharmaceuticals, Inc. |
Verfahren zur verbesserung der erfolgsquote von hämatopoetischen stammzellentransplantaten
|
AU2013208293B2
(en)
|
2012-01-09 |
2017-08-10 |
Serpin Pharma, Llc |
Peptides and methods of using same
|
US9133461B2
(en)
|
2012-04-10 |
2015-09-15 |
Alnylam Pharmaceuticals, Inc. |
Compositions and methods for inhibiting expression of the ALAS1 gene
|
US9127274B2
(en)
|
2012-04-26 |
2015-09-08 |
Alnylam Pharmaceuticals, Inc. |
Serpinc1 iRNA compositions and methods of use thereof
|
WO2014011705A1
(en)
|
2012-07-09 |
2014-01-16 |
The Regents Of The University Of California |
Vault immunotherapy
|
US9605074B2
(en)
|
2012-08-30 |
2017-03-28 |
The General Hospital Corporation |
Multifunctional nanobodies for treating cancer
|
HUE035887T2
(en)
|
2012-12-05 |
2018-05-28 |
Alnylam Pharmaceuticals Inc |
PCSK9 iRNA preparations and methods for their use
|
CN105473154A
(zh)
|
2013-03-12 |
2016-04-06 |
通用医疗公司 |
修饰的缪勒抑制物质(mis)蛋白及其用于疾病治疗的用途
|
SI2970974T1
(sl)
|
2013-03-14 |
2017-12-29 |
Alnylam Pharmaceuticals, Inc. |
Komplementarna komponenta C5 sestavkov IRNA in postopki njene uporabe
|
EP2978446B1
(de)
|
2013-03-27 |
2020-03-04 |
The General Hospital Corporation |
Anti-cd33 antikörper zur behandlung von morbus alzheimer
|
US10246708B2
(en)
|
2013-05-06 |
2019-04-02 |
Alnylam Pharmaceuticals, Inc. |
Dosages and methods for delivering lipid formulated nucleic acid molecules
|
AU2014268603B2
(en)
|
2013-05-21 |
2018-03-22 |
President And Fellows Of Harvard College |
Engineered heme-binding compositions and uses thereof
|
CN113018307A
(zh)
|
2013-05-22 |
2021-06-25 |
阿尔尼拉姆医药品有限公司 |
SERPINA1 iRNA组合物及其使用方法
|
IL293657A
(en)
|
2013-05-22 |
2022-08-01 |
Alnylam Pharmaceuticals Inc |
Preparations of tmprss6 irna and methods of using them
|
EP3052626A1
(de)
|
2013-10-02 |
2016-08-10 |
Alnylam Pharmaceuticals, Inc. |
Zusammensetzungen und verfahren zur hemmung der lect2-genexpression
|
PL3052628T3
(pl)
|
2013-10-04 |
2020-08-24 |
Alnylam Pharmaceuticals, Inc. |
Kompozycje i sposoby hamowania ekspresji genu ALAS1
|
GB201318804D0
(en)
|
2013-10-24 |
2013-12-11 |
Adaptimmune Ltd |
Vectors for transgene expression
|
AU2014362307A1
(en)
|
2013-12-11 |
2016-06-30 |
The General Hospital Corporation |
Use of mullerian inhibiting substance (MIS) proteins for contraception and ovarian reserve preservation
|
WO2015089368A2
(en)
|
2013-12-12 |
2015-06-18 |
Alnylam Pharmaceuticals, Inc. |
Complement component irna compositions and methods of use thereof
|
JP6594902B2
(ja)
|
2014-02-11 |
2019-10-23 |
アルナイラム ファーマシューティカルズ, インコーポレイテッド |
ケトヘキソキナーゼ(KHK)iRNA組成物及びその使用方法
|
WO2015175510A1
(en)
|
2014-05-12 |
2015-11-19 |
Alnylam Pharmaceuticals, Inc. |
Methods and compositions for treating a serpinc1-associated disorder
|
MX2016015126A
(es)
|
2014-05-22 |
2017-02-23 |
Alnylam Pharmaceuticals Inc |
Composiciones de angiotensinogeno (agt) arni y metodos de uso de las mismas.
|
JOP20200115A1
(ar)
|
2014-10-10 |
2017-06-16 |
Alnylam Pharmaceuticals Inc |
تركيبات وطرق لتثبيط التعبير الجيني عن hao1 (حمض أوكسيداز هيدروكسيلي 1 (أوكسيداز جليكولات))
|
JOP20200092A1
(ar)
|
2014-11-10 |
2017-06-16 |
Alnylam Pharmaceuticals Inc |
تركيبات iRNA لفيروس الكبد B (HBV) وطرق لاستخدامها
|
EP3221451A1
(de)
|
2014-11-17 |
2017-09-27 |
Alnylam Pharmaceuticals, Inc. |
Apolipoprotein-c3 (apoc3)-irna-zusammensetzungen und verfahren zur verwendung davon
|
EP3256587A2
(de)
|
2015-02-13 |
2017-12-20 |
Alnylam Pharmaceuticals, Inc. |
Patatin-like phospholipase domain containing-3 (pnpla3)-irna-zusammensetzungen und verfahren zur verwendung davon
|
EP3283529B1
(de)
|
2015-04-17 |
2023-06-07 |
The General Hospital Corporation |
Wirkstoffe, systeme und verfahren zur behandlung von krebs
|
EP3307316A1
(de)
|
2015-06-12 |
2018-04-18 |
Alnylam Pharmaceuticals, Inc. |
Gegen komplementkomponente c5 gerichtete irna-zusammensetzungen und verfahren zur verwendung davon
|
CA2996975C
(en)
|
2015-08-28 |
2022-02-15 |
Serpin Pharma, Llc |
Methods for treatment of diseases
|
WO2017214518A1
(en)
|
2016-06-10 |
2017-12-14 |
Alnylam Pharmaceuticals, Inc. |
COMPLETMENT COMPONENT C5 iRNA COMPOSTIONS AND METHODS OF USE THEREOF FOR TREATING PAROXYSMAL NOCTURNAL HEMOGLOBINURIA (PNH)
|
WO2018112320A1
(en)
|
2016-12-16 |
2018-06-21 |
Alnylam Pharmaceuticals, Inc. |
Methods for treating or preventing ttr-associated diseases using transthyretin (ttr) irna compositions
|
AU2018360697A1
(en)
|
2017-11-01 |
2020-05-14 |
Alnylam Pharmaceuticals, Inc. |
Complement component C3 iRNA compositions and methods of use thereof
|
EP3714054A1
(de)
|
2017-11-20 |
2020-09-30 |
Alnylam Pharmaceuticals, Inc. |
Serum-amyloid p-komponente (apcs) irna zusammensetzungen und verfahren zu deren verwendung
|
TW202020157A
(zh)
|
2018-08-16 |
2020-06-01 |
美商艾爾妮蘭製藥公司 |
用於抑制lect2基因表現之組合物及方法
|
WO2020061164A1
(en)
*
|
2018-09-19 |
2020-03-26 |
The Trustees Of Indiana University |
Vectors expressing color and selectable markers
|
US20210348192A1
(en)
*
|
2018-09-20 |
2021-11-11 |
National University Corporation Tokyo Medical And Dental University |
Method for increasing lentiviral vector production
|
US20210340568A1
(en)
*
|
2018-10-09 |
2021-11-04 |
The University Of North Carolina At Chapel Hill |
Regulated gene editing system
|
EP4025694A1
(de)
|
2019-09-03 |
2022-07-13 |
Alnylam Pharmaceuticals, Inc. |
Zusammensetzungen und verfahren zum hemmen der lect2-genexpression
|
EP4038189A1
(de)
|
2019-10-04 |
2022-08-10 |
Alnylam Pharmaceuticals, Inc. |
Zusammensetzungen und verfahren zum ausschalten einer ugt1a1-genexpression
|
EP4051796A1
(de)
|
2019-11-01 |
2022-09-07 |
Alnylam Pharmaceuticals, Inc. |
Zusammensetzungen und verfahren zum unterdrücken der dnajb1-prkaca-fusionsgenexpression
|
KR20220115946A
(ko)
|
2019-11-13 |
2022-08-19 |
알닐람 파마슈티칼스 인코포레이티드 |
안지오텐시노겐 (agt) 관련 장애를 치료하기 위한 방법 및 조성물
|
WO2021154941A1
(en)
|
2020-01-31 |
2021-08-05 |
Alnylam Pharmaceuticals, Inc. |
Complement component c5 irna compositions for use in the treatment of amyotrophic lateral sclerosis (als)
|
IL295445A
(en)
|
2020-02-10 |
2022-10-01 |
Alnylam Pharmaceuticals Inc |
Preparations and methods for silencing vegf-a expression
|
DE102020106710A1
(de)
|
2020-03-11 |
2021-09-16 |
Immatics US, Inc. |
Wpre-mutantenkonstrukte, zusammensetzungen und zugehörige verfahren
|
DE102020111571A1
(de)
|
2020-03-11 |
2021-09-16 |
Immatics US, Inc. |
Wpre-mutantenkonstrukte, zusammensetzungen und zugehörige verfahren
|
EP4127171A2
(de)
|
2020-03-30 |
2023-02-08 |
Alnylam Pharmaceuticals, Inc. |
Zusammensetzungen und verfahren zur ausschaltung der dnajc15-genexpression
|
BR112022020145A2
(pt)
|
2020-04-06 |
2023-01-03 |
Alnylam Pharmaceuticals Inc |
Composições e métodos para silenciamento da expressão de myoc
|
EP4133079A1
(de)
|
2020-04-07 |
2023-02-15 |
Alnylam Pharmaceuticals, Inc. |
Zusammensetzungen und verfahren zur ausschaltung der scn9a-expression
|
EP4153746A1
(de)
|
2020-05-21 |
2023-03-29 |
Alnylam Pharmaceuticals, Inc. |
Zusammensetzungen und verfahren zur hemmung der marc1-genexpression
|
EP4157923A2
(de)
|
2020-05-29 |
2023-04-05 |
President And Fellows Of Harvard College |
Mit polyphenolfunktionalisierten biologisch aktiven nanokomplexen manipulierte lebende zellen
|
AU2021365822A1
(en)
|
2020-10-21 |
2023-06-08 |
Alnylam Pharmaceuticals, Inc. |
Methods and compositions for treating primary hyperoxaluria
|
TW202237150A
(zh)
|
2020-12-01 |
2022-10-01 |
美商艾拉倫製藥股份有限公司 |
用於抑制hao1(羥基酸氧化酶1(乙醇酸氧化酶))基因表現的方法及組成物
|
KR20240026203A
(ko)
|
2021-06-30 |
2024-02-27 |
알닐람 파마슈티칼스 인코포레이티드 |
안지오텐시노겐(agt)-관련 장애를 치료하는 방법 및 조성물
|
CA3223081A1
(en)
|
2021-07-15 |
2023-01-19 |
Samir Mitragotri |
Compositions and methods relating to cells with adhered particles
|
GB202112471D0
(en)
|
2021-09-01 |
2021-10-13 |
King S College London |
Microna systems
|