JP6423152B2 - マイクロニードルデバイス及び方法 - Google Patents
マイクロニードルデバイス及び方法 Download PDFInfo
- Publication number
- JP6423152B2 JP6423152B2 JP2013557801A JP2013557801A JP6423152B2 JP 6423152 B2 JP6423152 B2 JP 6423152B2 JP 2013557801 A JP2013557801 A JP 2013557801A JP 2013557801 A JP2013557801 A JP 2013557801A JP 6423152 B2 JP6423152 B2 JP 6423152B2
- Authority
- JP
- Japan
- Prior art keywords
- microneedle
- local anesthetic
- microneedles
- coating
- array
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Active
Links
Images
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
- A61K9/0021—Intradermal administration, e.g. through microneedle arrays, needleless injectors
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M37/00—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M37/00—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
- A61M37/0015—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin by using microneedles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P23/00—Anaesthetics
- A61P23/02—Local anaesthetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M37/00—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
- A61M37/0015—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin by using microneedles
- A61M2037/0023—Drug applicators using microneedles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M37/00—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
- A61M37/0015—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin by using microneedles
- A61M2037/0046—Solid microneedles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M37/00—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
- A61M37/0015—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin by using microneedles
- A61M2037/0061—Methods for using microneedles
Landscapes
- Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Dermatology (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical & Material Sciences (AREA)
- Anesthesiology (AREA)
- Biomedical Technology (AREA)
- Heart & Thoracic Surgery (AREA)
- Epidemiology (AREA)
- Hematology (AREA)
- Medical Informatics (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Medicinal Preparation (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Media Introduction/Drainage Providing Device (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201161449993P | 2011-03-07 | 2011-03-07 | |
| US61/449,993 | 2011-03-07 | ||
| PCT/US2012/027857 WO2012122162A1 (en) | 2011-03-07 | 2012-03-06 | Microneedle devices and methods |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2017000354A Division JP2017105784A (ja) | 2011-03-07 | 2017-01-05 | マイクロニードルデバイス及び方法 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2014507473A JP2014507473A (ja) | 2014-03-27 |
| JP2014507473A5 JP2014507473A5 (enExample) | 2015-04-23 |
| JP6423152B2 true JP6423152B2 (ja) | 2018-11-14 |
Family
ID=45841653
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2013557801A Active JP6423152B2 (ja) | 2011-03-07 | 2012-03-06 | マイクロニードルデバイス及び方法 |
| JP2017000354A Pending JP2017105784A (ja) | 2011-03-07 | 2017-01-05 | マイクロニードルデバイス及び方法 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2017000354A Pending JP2017105784A (ja) | 2011-03-07 | 2017-01-05 | マイクロニードルデバイス及び方法 |
Country Status (9)
| Country | Link |
|---|---|
| US (1) | US20140066842A1 (enExample) |
| EP (1) | EP2683358B1 (enExample) |
| JP (2) | JP6423152B2 (enExample) |
| KR (1) | KR102058979B1 (enExample) |
| CN (1) | CN103402496B (enExample) |
| AU (1) | AU2012225608B2 (enExample) |
| BR (1) | BR112013022949A2 (enExample) |
| CA (1) | CA2829352A1 (enExample) |
| WO (1) | WO2012122162A1 (enExample) |
Families Citing this family (81)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB0402131D0 (en) | 2004-01-30 | 2004-03-03 | Isis Innovation | Delivery method |
| US20140066842A1 (en) * | 2011-03-07 | 2014-03-06 | 3M Innovative Properties Company | Microneedle devices and methods |
| EP2765927B1 (en) | 2011-10-12 | 2021-02-24 | Vaxxas Pty Limited | Delivery device |
| WO2013096026A1 (en) | 2011-12-21 | 2013-06-27 | 3M Innovative Properties Company | Transdermal adhesive patch assembly with removable microneedle array and method of using same |
| US12161831B2 (en) | 2012-09-13 | 2024-12-10 | Avraham Amir | Microneedles and compositions for skin augmentation |
| CN104661695B (zh) * | 2012-09-13 | 2019-02-15 | 亚夫拉罕·阿米尔 | 用于皮肤改善的递送装置和方法 |
| JP5472771B1 (ja) | 2012-09-28 | 2014-04-16 | コスメディ製薬株式会社 | 段差に薬物を保持したマイクロニードル |
| US9782574B2 (en) | 2012-10-10 | 2017-10-10 | 3M Innovative Properties Company | Force-controlled applicator for applying a microneedle device to skin |
| EP2906285B1 (en) | 2012-10-10 | 2019-06-12 | 3M Innovative Properties Company | Applicator for applying a microneedle device to skin |
| CN104797287B (zh) | 2012-11-16 | 2017-12-26 | 3M创新有限公司 | 力控施用装置 |
| EP2938390A1 (en) | 2012-12-27 | 2015-11-04 | 3M Innovative Properties Company | Article with hollow microneedles and method of making |
| US20150352295A1 (en) | 2013-01-08 | 2015-12-10 | 3M Innovative Properties Company | Application For Applying A Microneedle Device To Skin |
| CN105025976B (zh) * | 2013-01-21 | 2019-01-08 | 白雁美学公司 | 微型针、微型针的制造模具和制造方法 |
| JP6081215B2 (ja) * | 2013-02-13 | 2017-02-15 | 久光製薬株式会社 | コーティング及びマイクロニードルデバイス |
| SG11201507885TA (en) | 2013-03-22 | 2015-11-27 | 3M Innovative Properties Co | Microneedle applicator comprising a counter assembly |
| EP3003459B1 (en) | 2013-05-31 | 2018-06-20 | 3M Innovative Properties Company | Microneedle injection apparatus comprising an inverted actuator |
| US9872975B2 (en) | 2013-05-31 | 2018-01-23 | 3M Innovative Properties Company | Microneedle injection and infusion apparatus and method of using same |
| JP6494602B2 (ja) | 2013-05-31 | 2019-04-03 | スリーエム イノベイティブ プロパティズ カンパニー | 二重カバーを備えるマイクロニードル注射装置 |
| SG11201600330XA (en) | 2013-07-16 | 2016-02-26 | 3M Innovative Properties Co | Article comprising a microneedle |
| US10384047B2 (en) | 2013-07-16 | 2019-08-20 | 3M Innovative Properties Company | Hollow microneedle with bevel opening |
| US10099043B2 (en) | 2013-07-16 | 2018-10-16 | 3M Innovative Properties Company | Hollow microneedle array article |
| WO2015009524A1 (en) | 2013-07-16 | 2015-01-22 | 3M Innovative Properties Company | Hollow microneedle with beveled tip |
| GB201317641D0 (en) * | 2013-10-05 | 2013-11-20 | Chowdhury Dewan F H | Novel solid dosage form |
| US9833405B2 (en) | 2014-03-19 | 2017-12-05 | Nano And Advanced Materials Institute Limited | Biodegradable microdepot delivery system for topical delivery |
| CN104922093B (zh) * | 2014-03-19 | 2019-06-18 | 纳米及先进材料研发院有限公司 | 用于局部递送的可生物降解的微贮库型递送系统 |
| US20160279401A1 (en) | 2015-03-27 | 2016-09-29 | Allergan, Inc. | Dissolvable microneedles for skin treatment |
| KR101754309B1 (ko) * | 2014-08-21 | 2017-07-07 | 주식회사 주빅 | 음압을 이용한 마이크로구조체의 제조방법 및 그로부터 제조된 마이크로구조체 |
| SG11201701024WA (en) * | 2014-08-27 | 2017-03-30 | Neuronano Ab | Method of implantation of a medical device into neural tissue |
| KR102169536B1 (ko) | 2014-09-11 | 2020-10-23 | 히사미쓰 세이야꾸 가부시키가이샤 | 마이크로니들 디바이스 |
| SG11201702779PA (en) | 2014-10-27 | 2017-05-30 | Hisamitsu Pharmaceutical Co | Microneedle device containing recombinant follicle stimulating hormone |
| AU2016209496B2 (en) | 2015-01-21 | 2018-06-28 | Kindeva Drug Delivery L.P. | Microneedle array and method of use |
| JP2018502927A (ja) | 2015-01-27 | 2018-02-01 | スリーエム イノベイティブ プロパティズ カンパニー | マイクロニードルワクチンパッチ用ミョウバン含有コーティング製剤 |
| EP4218892A1 (en) | 2015-02-02 | 2023-08-02 | Vaxxas Pty Limited | Microprojection array applicator |
| JP5852280B1 (ja) | 2015-03-23 | 2016-02-03 | コスメディ製薬株式会社 | マイクロニードルおよびその製造 |
| KR102203635B1 (ko) * | 2015-06-10 | 2021-01-15 | 주식회사 엘지생활건강 | 속용해성 미세바늘 패치 |
| US11103259B2 (en) | 2015-09-18 | 2021-08-31 | Vaxxas Pty Limited | Microprojection arrays with microprojections having large surface area profiles |
| KR101610598B1 (ko) | 2015-09-21 | 2016-04-07 | 비엔엘바이오테크 주식회사 | 잇몸 굴곡에 맞게 유연하며 치과용 물질 전달을 위한 마이크로 니들 및 그 제작방법 |
| AU2016333148B2 (en) | 2015-09-28 | 2021-10-14 | Vaxxas Pty Limited | Microprojection arrays with enhanced skin penetrating properties and methods thereof |
| CN109069817B (zh) * | 2016-04-15 | 2021-07-13 | 富士胶片株式会社 | 微针阵列 |
| CN110114069B (zh) * | 2016-12-26 | 2022-03-04 | 久光制药株式会社 | 微针装置 |
| CN110035792A (zh) * | 2016-12-28 | 2019-07-19 | 考司美德制药株式会社 | 涂布含药成分的微针制剂 |
| AU2018222745B2 (en) | 2017-02-17 | 2021-02-18 | Allergan, Inc. | Microneedle array with active ingredient |
| CN115923337A (zh) | 2017-03-31 | 2023-04-07 | 瓦克萨斯私人有限公司 | 用于涂覆表面的设备和方法 |
| TWI633901B (zh) * | 2017-05-16 | 2018-09-01 | 怡定興科技股份有限公司 | 醫美微針貼片之製作方法 |
| WO2018227246A1 (en) | 2017-06-13 | 2018-12-20 | Vaxxas Pty Limited | Quality control of substrate coatings |
| JP6482604B2 (ja) * | 2017-06-22 | 2019-03-13 | 教裕 南郷 | 外皮内溶解型ニードル及びニードル装置 |
| US11464957B2 (en) | 2017-08-04 | 2022-10-11 | Vaxxas Pty Limited | Compact high mechanical energy storage and low trigger force actuator for the delivery of microprojection array patches (MAP) |
| CN109394237B (zh) * | 2017-08-17 | 2025-07-22 | 李泉 | 一种采血装置及其控制设备 |
| AU2018352317B2 (en) | 2017-10-17 | 2021-04-01 | Kindeva Drug Delivery L.P. | Applicator for applying a microneedle array to skin |
| KR102076394B1 (ko) * | 2017-10-30 | 2020-02-11 | 장은주 | 생체흡수 및 생체분해 소재의 주입기 |
| KR102091452B1 (ko) * | 2017-12-19 | 2020-03-20 | 대화제약 주식회사 | 국소 마취제 및 히알루론산 하이드로겔을 포함하는 사전충전형 주사기의 제조방법 |
| AU2019205874A1 (en) * | 2018-01-07 | 2020-07-02 | Avraham Amir | High-load microneedles and compositions for skin augmentation |
| WO2019166572A1 (en) | 2018-02-28 | 2019-09-06 | Pharming Intellectual Property B.V. | Pharmaceutical system for transdermal administration of a c1 -esterase inhibitor |
| JP2021526431A (ja) | 2018-05-16 | 2021-10-07 | キンデーバ ドラッグ デリバリー リミティド パートナーシップ | マイクロニードルバイオセンサ |
| US11460411B2 (en) * | 2018-06-18 | 2022-10-04 | Kindeva Drug Delivery L.P. | Process and apparatus for inspecting microneedle arrays |
| WO2020004234A1 (ja) | 2018-06-26 | 2020-01-02 | 久光製薬株式会社 | マイクロニードルデバイス及びそれを製造する方法 |
| CN109364017B (zh) * | 2018-09-03 | 2022-04-01 | 中山大学 | 快速分离型可溶性微针及其制备方法 |
| WO2020176807A1 (en) * | 2019-02-27 | 2020-09-03 | Vanderbilt University | Methods of treating trigeminal nerve pain |
| DE102019105694A1 (de) * | 2019-03-06 | 2020-09-10 | Lts Lohmann Therapie-Systeme Ag | Mikronadelarray aufweisend ein wärmeerzeugendes Element |
| AU2020255670B2 (en) * | 2019-03-29 | 2025-12-11 | Vaxxas Pty Ltd | Vaccination using high-density microprojection array patch |
| CN110664787B (zh) * | 2019-10-15 | 2022-05-27 | 福建医科大学附属第一医院 | 右美托咪定缓释微针阵列及其制备方法 |
| KR102120245B1 (ko) * | 2019-11-01 | 2020-06-08 | 변은진 | 눈썹 발모 시술 방법 |
| CN110755265A (zh) * | 2019-11-13 | 2020-02-07 | 辽宁中医药大学附属医院 | 一种无痛微针及其制备方法 |
| US20230045891A1 (en) * | 2019-12-23 | 2023-02-16 | Hisamitsu Pharmaceutical Co., Inc. | Microneedle device and method for producing same |
| CN115734798A (zh) | 2020-04-28 | 2023-03-03 | 提克纳有限责任公司 | 微针组件 |
| CN111939458A (zh) * | 2020-08-25 | 2020-11-17 | 四川大学 | 一种具有超薄柔性背衬层的微针贴片及其制备方法 |
| CN111991344B (zh) * | 2020-09-28 | 2023-01-13 | 四川大学 | 一种适用于局部麻醉的微针贴片及其制备方法 |
| US12214346B2 (en) | 2021-10-13 | 2025-02-04 | Satio, Inc. | Dermal patch with a diagnostic test strip |
| US11452474B1 (en) | 2021-04-14 | 2022-09-27 | Satio, Inc. | Dual lever dermal patch system |
| US12023156B2 (en) | 2021-10-13 | 2024-07-02 | Satio, Inc. | Dermal patch for collecting a physiological sample |
| US11964121B2 (en) | 2021-10-13 | 2024-04-23 | Satio, Inc. | Mono dose dermal patch for pharmaceutical delivery |
| US11877848B2 (en) | 2021-11-08 | 2024-01-23 | Satio, Inc. | Dermal patch for collecting a physiological sample |
| US12048543B2 (en) | 2021-11-08 | 2024-07-30 | Satio, Inc. | Dermal patch for collecting a physiological sample with removable vial |
| US12178979B2 (en) | 2021-10-13 | 2024-12-31 | Satio, Inc. | Dermal patch for delivering a pharmaceutical |
| US12053284B2 (en) | 2021-11-08 | 2024-08-06 | Satio, Inc. | Dermal patch for collecting a physiological sample |
| CN114129889B (zh) * | 2021-11-30 | 2023-12-19 | 温州医科大学 | 一种眼科用环形微针 |
| CN115227638B (zh) * | 2022-07-19 | 2025-03-18 | 广州新济生物医药研究院有限公司 | 一种盐酸右美托咪定可溶性微针及其制备方法 |
| AU2023371939A1 (en) | 2022-11-05 | 2025-05-22 | Kindeva Drug Delivery L.P. | Microneedle array applicator and system |
| WO2024129424A1 (en) | 2022-12-16 | 2024-06-20 | Kindeva Drug Delivery L.P. | Drug delivery device |
| CN115998670B (zh) * | 2023-01-28 | 2025-04-11 | 深圳青澜生物技术有限公司 | 一种麻醉缓释微针及其制备方法 |
| CN119970613A (zh) * | 2025-02-10 | 2025-05-13 | 中国人民解放军总医院 | 一种埃他卡林微针及其制备方法 |
Family Cites Families (22)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1156961A (zh) * | 1995-06-09 | 1997-08-13 | 欧罗赛铁克股份有限公司 | 产生长效局部麻醉的制剂和方法 |
| AU2001259848B2 (en) * | 2000-05-12 | 2005-10-13 | Septodont Holding Sas | Local anesthetic methods and kits |
| US6881203B2 (en) | 2001-09-05 | 2005-04-19 | 3M Innovative Properties Company | Microneedle arrays and methods of manufacturing the same |
| MXPA05000597A (es) | 2002-07-19 | 2005-04-28 | 3M Innovative Properties Co | Dispositivos de microaguja y aparatos de administracion por microaguja. |
| FR2846557B1 (fr) * | 2002-10-30 | 2007-06-08 | Statice Sante | Structure implantable pour la liberation prolongee et controlee d'un principe actif |
| US20050095277A1 (en) * | 2003-06-25 | 2005-05-05 | Binnur Ozturk | Neuropathy cream |
| BRPI0412021A (pt) | 2003-06-30 | 2006-08-15 | Alza Corp | método para revestir microprojeções de perfuração de pele |
| US20050228336A1 (en) * | 2004-04-07 | 2005-10-13 | Preston Keusch | Electrically assisted lidocaine and epinephrine delivery device having extended shelf-stability |
| WO2005123173A1 (en) | 2004-06-10 | 2005-12-29 | 3M Innovative Properties Company | Patch application device and kit |
| US20060253078A1 (en) * | 2005-04-25 | 2006-11-09 | Wu Jeffrey M | Method of treating skin disorders with stratum corneum piercing device |
| WO2006138719A2 (en) * | 2005-06-17 | 2006-12-28 | Georgia Tech Research Corporation | Coated microstructures and method of manufacture thereof |
| WO2007015441A1 (ja) * | 2005-08-01 | 2007-02-08 | Hisamitsu Pharmaceutical Co., Inc. | 経皮または経粘膜投与のためのアジュバントおよび製剤 |
| JP2007044258A (ja) * | 2005-08-10 | 2007-02-22 | Transcutaneous Technologies Inc | 注射針挿入孔付き経皮吸収用パッチ |
| JP2007089792A (ja) * | 2005-09-28 | 2007-04-12 | Nano Device & System Research Inc | 経皮投与装置 |
| WO2007116959A1 (ja) * | 2006-04-07 | 2007-10-18 | Hisamitsu Pharmaceutical Co., Inc. | マイクロニードルデバイスおよびマイクロニードル付き経皮薬物投与装置 |
| WO2008054362A2 (en) * | 2006-08-29 | 2008-05-08 | Nanomed Devices, Inc. | High-aspect-ratio microdevices and methods for transdermal delivery and sampling of active substances |
| JP5298011B2 (ja) * | 2007-05-15 | 2013-09-25 | 久光製薬株式会社 | マイクロニードルのコーティング方法 |
| EP2818184B1 (en) * | 2007-11-16 | 2018-10-31 | Allergan, Inc. | Compositions and methods for treating Purpura |
| JP5536661B2 (ja) * | 2008-10-30 | 2014-07-02 | 国立大学法人 岡山大学 | 局所麻酔用組成物 |
| JP5669145B2 (ja) * | 2009-07-02 | 2015-02-12 | 国立大学法人山口大学 | 表面麻酔剤 |
| US20140066842A1 (en) * | 2011-03-07 | 2014-03-06 | 3M Innovative Properties Company | Microneedle devices and methods |
| US10800040B1 (en) | 2017-12-14 | 2020-10-13 | Amazon Technologies, Inc. | Simulation-real world feedback loop for learning robotic control policies |
-
2012
- 2012-03-06 US US14/003,663 patent/US20140066842A1/en not_active Abandoned
- 2012-03-06 WO PCT/US2012/027857 patent/WO2012122162A1/en not_active Ceased
- 2012-03-06 CA CA2829352A patent/CA2829352A1/en not_active Abandoned
- 2012-03-06 EP EP12709231.0A patent/EP2683358B1/en active Active
- 2012-03-06 AU AU2012225608A patent/AU2012225608B2/en active Active
- 2012-03-06 KR KR1020137026209A patent/KR102058979B1/ko active Active
- 2012-03-06 CN CN201280012043.0A patent/CN103402496B/zh active Active
- 2012-03-06 BR BR112013022949A patent/BR112013022949A2/pt not_active Application Discontinuation
- 2012-03-06 JP JP2013557801A patent/JP6423152B2/ja active Active
-
2017
- 2017-01-05 JP JP2017000354A patent/JP2017105784A/ja active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| EP2683358B1 (en) | 2015-06-03 |
| AU2012225608A1 (en) | 2013-10-10 |
| KR20140013022A (ko) | 2014-02-04 |
| AU2012225608B2 (en) | 2015-07-02 |
| JP2017105784A (ja) | 2017-06-15 |
| BR112013022949A2 (pt) | 2016-12-06 |
| CN103402496B (zh) | 2016-01-20 |
| CA2829352A1 (en) | 2012-09-13 |
| CN103402496A (zh) | 2013-11-20 |
| KR102058979B1 (ko) | 2019-12-24 |
| JP2014507473A (ja) | 2014-03-27 |
| WO2012122162A1 (en) | 2012-09-13 |
| US20140066842A1 (en) | 2014-03-06 |
| EP2683358A1 (en) | 2014-01-15 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| JP6423152B2 (ja) | マイクロニードルデバイス及び方法 | |
| JP5941072B2 (ja) | マイクロニードルデバイス及び方法 | |
| JP6894455B2 (ja) | 治療剤の送達のためのマイクロアレイ、使用方法および製造方法 | |
| CN102917722B (zh) | 用于涂布微针阵列的水性制剂 | |
| EP2785327B1 (en) | Microneedle device having a peptide therapeutic agent and an amino acid, methods of making and using the same | |
| JP7219384B2 (ja) | 片頭痛および群発頭痛の治療に適したゾルミトリプタン治療濃度を迅速に得る方法 | |
| US20050226922A1 (en) | Apparatus and method for transdermal delivery of fentanyl-based agents | |
| KR20150052092A (ko) | 약제 조성물이 도포된 마이크로 니들 어레이 |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| A521 | Request for written amendment filed |
Free format text: JAPANESE INTERMEDIATE CODE: A523 Effective date: 20150304 |
|
| A621 | Written request for application examination |
Free format text: JAPANESE INTERMEDIATE CODE: A621 Effective date: 20150304 |
|
| A131 | Notification of reasons for refusal |
Free format text: JAPANESE INTERMEDIATE CODE: A131 Effective date: 20151215 |
|
| A521 | Request for written amendment filed |
Free format text: JAPANESE INTERMEDIATE CODE: A523 Effective date: 20160314 |
|
| A02 | Decision of refusal |
Free format text: JAPANESE INTERMEDIATE CODE: A02 Effective date: 20160906 |
|
| A521 | Request for written amendment filed |
Free format text: JAPANESE INTERMEDIATE CODE: A523 Effective date: 20170105 |
|
| A911 | Transfer to examiner for re-examination before appeal (zenchi) |
Free format text: JAPANESE INTERMEDIATE CODE: A911 Effective date: 20170113 |
|
| A912 | Re-examination (zenchi) completed and case transferred to appeal board |
Free format text: JAPANESE INTERMEDIATE CODE: A912 Effective date: 20170324 |
|
| A521 | Request for written amendment filed |
Free format text: JAPANESE INTERMEDIATE CODE: A523 Effective date: 20180809 |
|
| A61 | First payment of annual fees (during grant procedure) |
Free format text: JAPANESE INTERMEDIATE CODE: A61 Effective date: 20181018 |
|
| R150 | Certificate of patent or registration of utility model |
Ref document number: 6423152 Country of ref document: JP Free format text: JAPANESE INTERMEDIATE CODE: R150 |
|
| S111 | Request for change of ownership or part of ownership |
Free format text: JAPANESE INTERMEDIATE CODE: R313113 |
|
| R350 | Written notification of registration of transfer |
Free format text: JAPANESE INTERMEDIATE CODE: R350 |
|
| RD02 | Notification of acceptance of power of attorney |
Free format text: JAPANESE INTERMEDIATE CODE: R3D02 |
|
| R250 | Receipt of annual fees |
Free format text: JAPANESE INTERMEDIATE CODE: R250 |
|
| R250 | Receipt of annual fees |
Free format text: JAPANESE INTERMEDIATE CODE: R250 |
|
| R250 | Receipt of annual fees |
Free format text: JAPANESE INTERMEDIATE CODE: R250 |
|
| R250 | Receipt of annual fees |
Free format text: JAPANESE INTERMEDIATE CODE: R250 |
|
| R250 | Receipt of annual fees |
Free format text: JAPANESE INTERMEDIATE CODE: R250 |