JP6411492B2 - 多環式カルバモイルピリドン化合物およびｈｉｖ感染症を処置するためのその使用 - Google Patents

多環式カルバモイルピリドン化合物およびｈｉｖ感染症を処置するためのその使用 Download PDF

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JP6411492B2
JP6411492B2 JP2016525820A JP2016525820A JP6411492B2 JP 6411492 B2 JP6411492 B2 JP 6411492B2 JP 2016525820 A JP2016525820 A JP 2016525820A JP 2016525820 A JP2016525820 A JP 2016525820A JP 6411492 B2 JP6411492 B2 JP 6411492B2
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JP2016525102A5 (enExample
JP2016525102A (ja
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ミンジュ ジ
ミンジュ ジ
テレサ アレハンドラ トレホ マーティン
テレサ アレハンドラ トレホ マーティン
マノジュ シー デサイ
マノジュ シー デサイ
ハオルン ジン
ハオルン ジン
ヒュン−ジュン ピュン
ヒュン−ジュン ピュン
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ギリアード サイエンシス インコーポレーテッド
ギリアード サイエンシス インコーポレーテッド
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/4985—Pyrazines or piperazines ortho- or peri-condensed with heterocyclic ring systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A61P31/18—Antivirals for RNA viruses for HIV
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/12—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains three hetero rings
    • C07D471/14—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/12—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains three hetero rings
    • C07D471/18—Bridged systems

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Epidemiology (AREA)
  • Oncology (AREA)
  • Virology (AREA)
  • Communicable Diseases (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Molecular Biology (AREA)
  • AIDS & HIV (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pyridine Compounds (AREA)
JP2016525820A 2013-07-12 2014-07-11 多環式カルバモイルピリドン化合物およびｈｉｖ感染症を処置するためのその使用 Active JP6411492B2 (ja)

Applications Claiming Priority (3)

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US201361845807P 2013-07-12 2013-07-12
US61/845,807 2013-07-12
PCT/US2014/046415 WO2015006733A1 (en) 2013-07-12 2014-07-11 Polycyclic-carbamoylpyridone compounds and their use for the treatment of hiv infections

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JP2016525102A JP2016525102A (ja) 2016-08-22
JP2016525102A5 JP2016525102A5 (enExample) 2017-08-24
JP6411492B2 true JP6411492B2 (ja) 2018-10-24

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US (6) US9458159B2 (enExample)
EP (2) EP3252053B1 (enExample)
JP (1) JP6411492B2 (enExample)
AU (3) AU2014286995B2 (enExample)
CA (1) CA2918055C (enExample)
CY (1) CY1119545T1 (enExample)
DK (1) DK3019499T3 (enExample)
ES (2) ES2856867T3 (enExample)
HR (1) HRP20171807T1 (enExample)
HU (1) HUE037343T2 (enExample)
LT (1) LT3019499T (enExample)
NO (1) NO2865735T3 (enExample)
PL (1) PL3019499T3 (enExample)
PT (1) PT3019499T (enExample)
RS (1) RS56539B1 (enExample)
SI (2) SI3019499T1 (enExample)
SM (1) SMT201700525T1 (enExample)
WO (1) WO2015006733A1 (enExample)

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US20220233525A1 (en) 2022-07-28
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