JP6357111B2 - コードされている治療用タンパク質の発現を増加させるための、ヒストンステムループとポリ(a)配列又はポリアデニル化シグナルとを含むか又はコードしている核酸 - Google Patents

コードされている治療用タンパク質の発現を増加させるための、ヒストンステムループとポリ(a)配列又はポリアデニル化シグナルとを含むか又はコードしている核酸 Download PDF

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JP6357111B2
JP6357111B2 JP2014556959A JP2014556959A JP6357111B2 JP 6357111 B2 JP6357111 B2 JP 6357111B2 JP 2014556959 A JP2014556959 A JP 2014556959A JP 2014556959 A JP2014556959 A JP 2014556959A JP 6357111 B2 JP6357111 B2 JP 6357111B2
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protein
nucleic acid
sequence
syndrome
disease
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JP2015508646A (ja
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アンドレアス・テース
トーマス・シャルケ
ヨッヘン・プロプスト
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Curevac SE
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JP2014556959A 2012-02-15 2013-02-15 コードされている治療用タンパク質の発現を増加させるための、ヒストンステムループとポリ(a)配列又はポリアデニル化シグナルとを含むか又はコードしている核酸 Active JP6357111B2 (ja)

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Application Number Priority Date Filing Date Title
PCT/EP2012/000671 WO2013120497A1 (en) 2012-02-15 2012-02-15 Nucleic acid comprising or coding for a histone stem-loop and a poly(a) sequence or a polyadenylation signal for increasing the expression of an encoded therapeutic protein
EPPCT/EP2012/000671 2012-02-15
PCT/EP2013/000461 WO2013120629A1 (en) 2012-02-15 2013-02-15 Nucleic acid comprising or coding for a histone stem-loop and a poly(a) sequence or a polyadenylation signal for increasing the expression of an encoded therapeutic protein

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JP2018032670A Division JP6720235B2 (ja) 2012-02-15 2018-02-27 コードされている治療用タンパク質の発現を増加させるための、ヒストンステムループとポリ(a)配列又はポリアデニル化シグナルとを含むか又はコードしている核酸

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JP2015508646A JP2015508646A (ja) 2015-03-23
JP6357111B2 true JP6357111B2 (ja) 2018-07-11

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JP2018032670A Active JP6720235B2 (ja) 2012-02-15 2018-02-27 コードされている治療用タンパク質の発現を増加させるための、ヒストンステムループとポリ(a)配列又はポリアデニル化シグナルとを含むか又はコードしている核酸
JP2020104281A Active JP6922038B2 (ja) 2012-02-15 2020-06-17 コードされている治療用タンパク質の発現を増加させるための、ヒストンステムループとポリ(a)配列又はポリアデニル化シグナルとを含むか又はコードしている核酸

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JP2020104281A Active JP6922038B2 (ja) 2012-02-15 2020-06-17 コードされている治療用タンパク質の発現を増加させるための、ヒストンステムループとポリ(a)配列又はポリアデニル化シグナルとを含むか又はコードしている核酸

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US (5) US9447431B2 (enExample)
EP (2) EP3741859A1 (enExample)
JP (3) JP6357111B2 (enExample)
KR (1) KR102072013B1 (enExample)
CN (2) CN104114705B (enExample)
AU (1) AU2013220749B2 (enExample)
BR (1) BR112014019627A2 (enExample)
CA (1) CA2862476C (enExample)
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JP2018110588A (ja) * 2012-02-15 2018-07-19 キュアバック アーゲー コードされている治療用タンパク質の発現を増加させるための、ヒストンステムループとポリ(a)配列又はポリアデニル化シグナルとを含むか又はコードしている核酸

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