DK2814963T3 - Nukleinsyre omfattende eller kodende for en histonhårnåleløkke og en poly(a)-sekvens eller et polyadenyleringssignal for at øge ekspression af et indkodet terapeutisk protein - Google Patents

Nukleinsyre omfattende eller kodende for en histonhårnåleløkke og en poly(a)-sekvens eller et polyadenyleringssignal for at øge ekspression af et indkodet terapeutisk protein Download PDF

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DK2814963T3
DK2814963T3 DK13704552.2T DK13704552T DK2814963T3 DK 2814963 T3 DK2814963 T3 DK 2814963T3 DK 13704552 T DK13704552 T DK 13704552T DK 2814963 T3 DK2814963 T3 DK 2814963T3
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histonic
coding
poly
sequence
nucleic acid
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DK13704552.2T
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Andreas Thess
Thomas Schlake
Jochen Probst
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Curevac Ag
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    • C12N15/67—General methods for enhancing the expression
    • C12N15/68—Stabilisation of the vector
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    • C07K2317/00—Immunoglobulins specific features
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DK13704552.2T 2012-02-15 2013-02-15 Nukleinsyre omfattende eller kodende for en histonhårnåleløkke og en poly(a)-sekvens eller et polyadenyleringssignal for at øge ekspression af et indkodet terapeutisk protein DK2814963T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
PCT/EP2012/000671 WO2013120497A1 (en) 2012-02-15 2012-02-15 Nucleic acid comprising or coding for a histone stem-loop and a poly(a) sequence or a polyadenylation signal for increasing the expression of an encoded therapeutic protein
PCT/EP2013/000461 WO2013120629A1 (en) 2012-02-15 2013-02-15 Nucleic acid comprising or coding for a histone stem-loop and a poly(a) sequence or a polyadenylation signal for increasing the expression of an encoded therapeutic protein

Publications (1)

Publication Number Publication Date
DK2814963T3 true DK2814963T3 (da) 2020-07-27

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DK13704552.2T DK2814963T3 (da) 2012-02-15 2013-02-15 Nukleinsyre omfattende eller kodende for en histonhårnåleløkke og en poly(a)-sekvens eller et polyadenyleringssignal for at øge ekspression af et indkodet terapeutisk protein

Country Status (15)

Country Link
US (5) US9447431B2 (da)
EP (2) EP2814963B1 (da)
JP (3) JP6357111B2 (da)
KR (1) KR102072013B1 (da)
CN (2) CN104114705B (da)
AU (1) AU2013220749B2 (da)
BR (1) BR112014019627A2 (da)
CA (1) CA2862476C (da)
DK (1) DK2814963T3 (da)
ES (1) ES2806678T3 (da)
IN (1) IN2014DN05670A (da)
MX (1) MX359953B (da)
RU (1) RU2634391C2 (da)
SG (2) SG11201403944RA (da)
WO (2) WO2013120497A1 (da)

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BR112014019627A2 (pt) 2017-06-27
EP2814963A1 (en) 2014-12-24
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AU2013220749A1 (en) 2014-07-24
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CN108570468A (zh) 2018-09-25
MX359953B (es) 2018-10-17
SG10201606784QA (en) 2016-12-29
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US9447431B2 (en) 2016-09-20
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