BR112023000537A2 - Composições farmacêuticas incluindo célula que expressa o receptor quimérico - Google Patents
Composições farmacêuticas incluindo célula que expressa o receptor quiméricoInfo
- Publication number
- BR112023000537A2 BR112023000537A2 BR112023000537A BR112023000537A BR112023000537A2 BR 112023000537 A2 BR112023000537 A2 BR 112023000537A2 BR 112023000537 A BR112023000537 A BR 112023000537A BR 112023000537 A BR112023000537 A BR 112023000537A BR 112023000537 A2 BR112023000537 A2 BR 112023000537A2
- Authority
- BR
- Brazil
- Prior art keywords
- chimeric receptor
- immunoreceptor
- pharmaceutical compositions
- extracellular domain
- compositions including
- Prior art date
Links
- 108700010039 chimeric receptor Proteins 0.000 title abstract 4
- 239000008194 pharmaceutical composition Substances 0.000 title abstract 3
- 239000000427 antigen Substances 0.000 abstract 4
- 108091007433 antigens Proteins 0.000 abstract 4
- 102000036639 antigens Human genes 0.000 abstract 4
- 239000012634 fragment Substances 0.000 abstract 1
Classifications
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- A61K39/0005—Vertebrate antigens
- A61K39/0011—Cancer antigens
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
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- A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
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- A61K39/46—Cellular immunotherapy
- A61K39/461—Cellular immunotherapy characterised by the cell type used
- A61K39/4611—T-cells, e.g. tumor infiltrating lymphocytes [TIL], lymphokine-activated killer cells [LAK] or regulatory T cells [Treg]
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Abstract
COMPOSIÇÕES FARMACÊUTICAS INCLUINDO CÉLULA QUE EXPRESSA O RECEPTOR QUIMÉRICO. A presente invenção refere-se a uma composição farmacêutica que inclui células que expressam um receptor quimérico, para uso em combinação com a administração de uma molécula de ligação ao antígeno, o receptor quimérico incluindo um domínio extracelular, o domínio extracelular incluindo um domínio extracelular do imunorreceptor, uma variante do domínio extracelular do imunorreceptor, ou um fragmento dos mesmos, e a molécula de ligação ao antígeno sendo uma molécula de ligação ao antígeno multiespecífica tendo um sítio de reconhecimento de antígeno alvo e um sítio de reconhecimento do imunorreceptor que reconhece o imunorreceptor.
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JP2020131116 | 2020-07-31 | ||
PCT/JP2021/028230 WO2022025220A1 (ja) | 2020-07-31 | 2021-07-30 | キメラ受容体を発現する細胞を含む医薬組成物 |
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BR112023000537A2 true BR112023000537A2 (pt) | 2023-01-31 |
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ID=80036292
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BR112023000537A BR112023000537A2 (pt) | 2020-07-31 | 2021-07-30 | Composições farmacêuticas incluindo célula que expressa o receptor quimérico |
Country Status (12)
Country | Link |
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US (1) | US20230322898A1 (pt) |
EP (1) | EP4197545A1 (pt) |
JP (1) | JPWO2022025220A1 (pt) |
KR (1) | KR20230048059A (pt) |
CN (1) | CN116194124A (pt) |
AU (1) | AU2021317974A1 (pt) |
BR (1) | BR112023000537A2 (pt) |
CA (1) | CA3190649A1 (pt) |
IL (1) | IL300225A (pt) |
MX (1) | MX2023001120A (pt) |
TW (1) | TW202220677A (pt) |
WO (1) | WO2022025220A1 (pt) |
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2021
- 2021-07-30 KR KR1020237006010A patent/KR20230048059A/ko unknown
- 2021-07-30 IL IL300225A patent/IL300225A/en unknown
- 2021-07-30 WO PCT/JP2021/028230 patent/WO2022025220A1/ja active Application Filing
- 2021-07-30 US US18/018,807 patent/US20230322898A1/en active Pending
- 2021-07-30 MX MX2023001120A patent/MX2023001120A/es unknown
- 2021-07-30 EP EP21850145.0A patent/EP4197545A1/en active Pending
- 2021-07-30 CN CN202180058518.9A patent/CN116194124A/zh active Pending
- 2021-07-30 BR BR112023000537A patent/BR112023000537A2/pt unknown
- 2021-07-30 AU AU2021317974A patent/AU2021317974A1/en active Pending
- 2021-07-30 TW TW110128090A patent/TW202220677A/zh unknown
- 2021-07-30 CA CA3190649A patent/CA3190649A1/en active Pending
- 2021-07-30 JP JP2022539585A patent/JPWO2022025220A1/ja active Pending
Also Published As
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TW202220677A (zh) | 2022-06-01 |
IL300225A (en) | 2023-03-01 |
CA3190649A1 (en) | 2022-02-03 |
US20230322898A1 (en) | 2023-10-12 |
MX2023001120A (es) | 2023-02-22 |
EP4197545A1 (en) | 2023-06-21 |
CN116194124A (zh) | 2023-05-30 |
KR20230048059A (ko) | 2023-04-10 |
AU2021317974A1 (en) | 2023-03-16 |
WO2022025220A1 (ja) | 2022-02-03 |
JPWO2022025220A1 (pt) | 2022-02-03 |
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