JP6357111B2 - コードされている治療用タンパク質の発現を増加させるための、ヒストンステムループとポリ（ａ）配列又はポリアデニル化シグナルとを含むか又はコードしている核酸 - Google Patents

コードされている治療用タンパク質の発現を増加させるための、ヒストンステムループとポリ（ａ）配列又はポリアデニル化シグナルとを含むか又はコードしている核酸 Download PDF

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JP6357111B2
JP6357111B2 JP2014556959A JP2014556959A JP6357111B2 JP 6357111 B2 JP6357111 B2 JP 6357111B2 JP 2014556959 A JP2014556959 A JP 2014556959A JP 2014556959 A JP2014556959 A JP 2014556959A JP 6357111 B2 JP6357111 B2 JP 6357111B2
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protein
nucleic acid
sequence
syndrome
disease
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JP2015508646A (ja
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アンドレアス・テース
トーマス・シャルケ
ヨッヘン・プロプスト
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Curevac SE
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JP2014556959A 2012-02-15 2013-02-15 コードされている治療用タンパク質の発現を増加させるための、ヒストンステムループとポリ（ａ）配列又はポリアデニル化シグナルとを含むか又はコードしている核酸 Active JP6357111B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
PCT/EP2012/000671 WO2013120497A1 (en) 2012-02-15 2012-02-15 Nucleic acid comprising or coding for a histone stem-loop and a poly(a) sequence or a polyadenylation signal for increasing the expression of an encoded therapeutic protein
EPPCT/EP2012/000671 2012-02-15
PCT/EP2013/000461 WO2013120629A1 (en) 2012-02-15 2013-02-15 Nucleic acid comprising or coding for a histone stem-loop and a poly(a) sequence or a polyadenylation signal for increasing the expression of an encoded therapeutic protein

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JP2018032670A Division JP6720235B2 (ja) 2012-02-15 2018-02-27 コードされている治療用タンパク質の発現を増加させるための、ヒストンステムループとポリ（ａ）配列又はポリアデニル化シグナルとを含むか又はコードしている核酸

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JP2015508646A JP2015508646A (ja) 2015-03-23
JP6357111B2 true JP6357111B2 (ja) 2018-07-11

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JP2014556959A Active JP6357111B2 (ja) 2012-02-15 2013-02-15 コードされている治療用タンパク質の発現を増加させるための、ヒストンステムループとポリ（ａ）配列又はポリアデニル化シグナルとを含むか又はコードしている核酸
JP2018032670A Active JP6720235B2 (ja) 2012-02-15 2018-02-27 コードされている治療用タンパク質の発現を増加させるための、ヒストンステムループとポリ（ａ）配列又はポリアデニル化シグナルとを含むか又はコードしている核酸
JP2020104281A Active JP6922038B2 (ja) 2012-02-15 2020-06-17 コードされている治療用タンパク質の発現を増加させるための、ヒストンステムループとポリ（ａ）配列又はポリアデニル化シグナルとを含むか又はコードしている核酸

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JP2020104281A Active JP6922038B2 (ja) 2012-02-15 2020-06-17 コードされている治療用タンパク質の発現を増加させるための、ヒストンステムループとポリ（ａ）配列又はポリアデニル化シグナルとを含むか又はコードしている核酸

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US (5) US9447431B2 (OSRAM)
EP (2) EP3741859A1 (OSRAM)
JP (3) JP6357111B2 (OSRAM)
KR (1) KR102072013B1 (OSRAM)
CN (2) CN104114705B (OSRAM)
AU (1) AU2013220749B2 (OSRAM)
BR (1) BR112014019627A2 (OSRAM)
CA (1) CA2862476C (OSRAM)
DK (1) DK2814963T3 (OSRAM)
ES (1) ES2806678T3 (OSRAM)
IN (1) IN2014DN05670A (OSRAM)
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JP2018110588A (ja) * 2012-02-15 2018-07-19 キュアバック アーゲー コードされている治療用タンパク質の発現を増加させるための、ヒストンステムループとポリ（ａ）配列又はポリアデニル化シグナルとを含むか又はコードしている核酸

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