JP6210754B2 - 走査型光学顕微鏡 - Google Patents

走査型光学顕微鏡 Download PDF

Info

Publication number
JP6210754B2
JP6210754B2 JP2013131824A JP2013131824A JP6210754B2 JP 6210754 B2 JP6210754 B2 JP 6210754B2 JP 2013131824 A JP2013131824 A JP 2013131824A JP 2013131824 A JP2013131824 A JP 2013131824A JP 6210754 B2 JP6210754 B2 JP 6210754B2
Authority
JP
Japan
Prior art keywords
light
optical system
scanning
modulation element
laser
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
JP2013131824A
Other languages
English (en)
Japanese (ja)
Other versions
JP2015007661A (ja
JP2015007661A5 (enExample
Inventor
島田　佳弘
佳弘 島田
上野　牧男
牧男 上野
真悟 玉野
真悟 玉野
林　直樹
直樹 林
英司 横井
英司 横井
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Olympus Corp
Original Assignee
Olympus Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Olympus Corp filed Critical Olympus Corp
Priority to JP2013131824A priority Critical patent/JP6210754B2/ja
Priority to US14/298,707 priority patent/US9261689B2/en
Priority to EP14173633.0A priority patent/EP2827180B1/en
Publication of JP2015007661A publication Critical patent/JP2015007661A/ja
Publication of JP2015007661A5 publication Critical patent/JP2015007661A5/ja
Application granted granted Critical
Publication of JP6210754B2 publication Critical patent/JP6210754B2/ja
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Images

Classifications

    • G—PHYSICS
    • G02—OPTICS
    • G02B—OPTICAL ELEMENTS, SYSTEMS OR APPARATUS
    • G02B21/00—Microscopes
    • G02B21/0004—Microscopes specially adapted for specific applications
    • G02B21/002—Scanning microscopes
    • G02B21/0024—Confocal scanning microscopes (CSOMs) or confocal "macroscopes"; Accessories which are not restricted to use with CSOMs, e.g. sample holders
    • G02B21/0032—Optical details of illumination, e.g. light-sources, pinholes, beam splitters, slits, fibers
    • G—PHYSICS
    • G02—OPTICS
    • G02B—OPTICAL ELEMENTS, SYSTEMS OR APPARATUS
    • G02B21/00—Microscopes
    • G02B21/0004—Microscopes specially adapted for specific applications
    • G02B21/002—Scanning microscopes
    • G—PHYSICS
    • G02—OPTICS
    • G02B—OPTICAL ELEMENTS, SYSTEMS OR APPARATUS
    • G02B21/00—Microscopes
    • G02B21/0004—Microscopes specially adapted for specific applications
    • G02B21/002—Scanning microscopes
    • G02B21/0024—Confocal scanning microscopes (CSOMs) or confocal "macroscopes"; Accessories which are not restricted to use with CSOMs, e.g. sample holders
    • G02B21/0036—Scanning details, e.g. scanning stages
    • G—PHYSICS
    • G02—OPTICS
    • G02B—OPTICAL ELEMENTS, SYSTEMS OR APPARATUS
    • G02B21/00—Microscopes
    • G02B21/0096—Microscopes with photometer devices
    • G—PHYSICS
    • G02—OPTICS
    • G02B—OPTICAL ELEMENTS, SYSTEMS OR APPARATUS
    • G02B21/00—Microscopes
    • G02B21/06—Means for illuminating specimens
    • G—PHYSICS
    • G02—OPTICS
    • G02B—OPTICAL ELEMENTS, SYSTEMS OR APPARATUS
    • G02B21/00—Microscopes
    • G02B21/24—Base structure
    • G02B21/26—Stages; Adjusting means therefor
    • G—PHYSICS
    • G02—OPTICS
    • G02B—OPTICAL ELEMENTS, SYSTEMS OR APPARATUS
    • G02B27/00—Optical systems or apparatus not provided for by any of the groups G02B1/00 - G02B26/00, G02B30/00
    • G02B27/42—Diffraction optics, i.e. systems including a diffractive element being designed for providing a diffractive effect
    • G02B27/4261—Diffraction optics, i.e. systems including a diffractive element being designed for providing a diffractive effect having a diffractive element with major polarization dependent properties

Landscapes

  • Physics & Mathematics (AREA)
  • General Physics & Mathematics (AREA)
  • Optics & Photonics (AREA)
  • Chemical & Material Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Microscoopes, Condenser (AREA)
  • Nonlinear Science (AREA)
JP2013131824A 2013-06-24 2013-06-24 走査型光学顕微鏡 Active JP6210754B2 (ja)

Priority Applications (3)

Application Number Priority Date Filing Date Title
JP2013131824A JP6210754B2 (ja) 2013-06-24 2013-06-24 走査型光学顕微鏡
US14/298,707 US9261689B2 (en) 2013-06-24 2014-06-06 Scanning optical microscope
EP14173633.0A EP2827180B1 (en) 2013-06-24 2014-06-24 Scanning optical microscope

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP2013131824A JP6210754B2 (ja) 2013-06-24 2013-06-24 走査型光学顕微鏡

Publications (3)

Publication Number Publication Date
JP2015007661A JP2015007661A (ja) 2015-01-15
JP2015007661A5 JP2015007661A5 (enExample) 2016-07-21
JP6210754B2 true JP6210754B2 (ja) 2017-10-11

Family

ID=50979669

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2013131824A Active JP6210754B2 (ja) 2013-06-24 2013-06-24 走査型光学顕微鏡

Country Status (3)

Country Link
US (1) US9261689B2 (enExample)
EP (1) EP2827180B1 (enExample)
JP (1) JP6210754B2 (enExample)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN107923591B (zh) * 2015-09-07 2021-02-19 大日本印刷株式会社 照明装置
JP2017203822A (ja) * 2016-05-09 2017-11-16 オリンパス株式会社 照明設定方法、シート照明顕微鏡装置、及びプログラム
US11506877B2 (en) 2016-11-10 2022-11-22 The Trustees Of Columbia University In The City Of New York Imaging instrument having objective axis and light sheet or light beam projector axis intersecting at less than 90 degrees
JP6784773B2 (ja) * 2016-11-17 2020-11-11 オリンパス株式会社 標本観察装置
JP7070581B2 (ja) * 2017-09-26 2022-05-18 株式会社ニコン パターン描画装置

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP4786027B2 (ja) * 2000-12-08 2011-10-05 オリンパス株式会社 光学系及び光学装置
JP3861000B2 (ja) * 2001-12-25 2006-12-20 オリンパス株式会社 走査型レーザー顕微鏡
JP4729269B2 (ja) 2004-06-01 2011-07-20 オリンパス株式会社 レーザ走査型顕微鏡
EP1710609A1 (en) * 2005-04-08 2006-10-11 Deutsches Krebsforschungszentrum Stiftung des öffentlichen Rechts Optical scanning device and method of deriving same
JP4922628B2 (ja) 2006-03-03 2012-04-25 オリンパス株式会社 走査型レーザ顕微鏡
JP4885685B2 (ja) * 2006-11-06 2012-02-29 オリンパス株式会社 光学装置および顕微鏡
JP5153171B2 (ja) * 2007-03-16 2013-02-27 オリンパス株式会社 顕微鏡装置とその制御方法
JP5259154B2 (ja) * 2007-10-24 2013-08-07 オリンパス株式会社 走査型レーザ顕微鏡
US9116353B2 (en) 2008-09-16 2015-08-25 Yokogawa Electric Corporation Microscope device
JP5699421B2 (ja) * 2008-09-16 2015-04-08 横河電機株式会社 顕微鏡装置
EP2360505B1 (en) 2010-01-21 2017-03-01 Olympus Corporation Microscope apparatus
JP2012103379A (ja) * 2010-11-09 2012-05-31 Lasertec Corp 共焦点顕微鏡、及び焦点位置調整方法
DE102011000835C5 (de) * 2011-02-21 2019-08-22 Leica Microsystems Cms Gmbh Abtastmikroskop und Verfahren zur lichtmikroskopischen Abbildung eines Objektes
JP6006053B2 (ja) * 2012-09-06 2016-10-12 アストロデザイン株式会社 レーザー走査蛍光顕微鏡装置

Also Published As

Publication number Publication date
US9261689B2 (en) 2016-02-16
JP2015007661A (ja) 2015-01-15
US20140376078A1 (en) 2014-12-25
EP2827180B1 (en) 2017-03-01
EP2827180A1 (en) 2015-01-21

Similar Documents

Publication Publication Date Title
JP5259154B2 (ja) 走査型レーザ顕微鏡
CN106133580B (zh) 受激发射损耗显微镜装置
JP3996783B2 (ja) 走査型顕微鏡及び走査型顕微鏡用モジュール
US20160124201A1 (en) Light sheet illumination microscope and light sheet illumination method
US10191263B2 (en) Scanning microscopy system
JP5265070B2 (ja) 走査型顕微鏡検査における照明用光源装置、及び走査型顕微鏡
JP6526678B2 (ja) 偏光式のサンプル照明部を備えた走査顕微鏡
EP1835323B1 (en) Fluorescence microscope and observation method
CN103257130A (zh) 受激辐射损耗显微成像系统
JP6210754B2 (ja) 走査型光学顕微鏡
CN111103678B (zh) 晶格光片显微镜和在晶格光片显微镜中平铺晶格光片的方法
KR20130092429A (ko) 화상 생성 장치
JP2013130853A (ja) 顕微鏡装置
JP2010266813A (ja) 観察装置
US20070076199A1 (en) Laser microscope
US10690897B2 (en) Laser scanning microscope apparatus
JP4885429B2 (ja) 光刺激装置および光走査型観察装置
JP5699421B2 (ja) 顕微鏡装置
CN107209360B (zh) 图像取得装置以及图像取得方法
CN109073873B (zh) 图像取得装置以及图像取得方法
CN112567281A (zh) 用于显微镜的照明总成、显微镜和用于照明显微镜中的样本空间的方法
JP2016105126A (ja) 顕微鏡装置
WO2019130372A1 (ja) 光学分析装置
JP5765569B2 (ja) 顕微鏡装置
US10401293B2 (en) Microscope and microscope observation method

Legal Events

Date Code Title Description
A621 Written request for application examination

Free format text: JAPANESE INTERMEDIATE CODE: A621

Effective date: 20151203

A521 Request for written amendment filed

Free format text: JAPANESE INTERMEDIATE CODE: A523

Effective date: 20160601

A977 Report on retrieval

Free format text: JAPANESE INTERMEDIATE CODE: A971007

Effective date: 20161021

A131 Notification of reasons for refusal

Free format text: JAPANESE INTERMEDIATE CODE: A131

Effective date: 20161109

A521 Request for written amendment filed

Free format text: JAPANESE INTERMEDIATE CODE: A523

Effective date: 20170106

A131 Notification of reasons for refusal

Free format text: JAPANESE INTERMEDIATE CODE: A131

Effective date: 20170607

A521 Request for written amendment filed

Free format text: JAPANESE INTERMEDIATE CODE: A523

Effective date: 20170731

TRDD Decision of grant or rejection written
A01 Written decision to grant a patent or to grant a registration (utility model)

Free format text: JAPANESE INTERMEDIATE CODE: A01

Effective date: 20170816

A61 First payment of annual fees (during grant procedure)

Free format text: JAPANESE INTERMEDIATE CODE: A61

Effective date: 20170912

R151 Written notification of patent or utility model registration

Ref document number: 6210754

Country of ref document: JP

Free format text: JAPANESE INTERMEDIATE CODE: R151

R250 Receipt of annual fees

Free format text: JAPANESE INTERMEDIATE CODE: R250

R250 Receipt of annual fees

Free format text: JAPANESE INTERMEDIATE CODE: R250

R250 Receipt of annual fees

Free format text: JAPANESE INTERMEDIATE CODE: R250

S111 Request for change of ownership or part of ownership

Free format text: JAPANESE INTERMEDIATE CODE: R313111

R371 Transfer withdrawn

Free format text: JAPANESE INTERMEDIATE CODE: R371

S111 Request for change of ownership or part of ownership

Free format text: JAPANESE INTERMEDIATE CODE: R313111

R350 Written notification of registration of transfer

Free format text: JAPANESE INTERMEDIATE CODE: R350

R250 Receipt of annual fees

Free format text: JAPANESE INTERMEDIATE CODE: R250

R250 Receipt of annual fees

Free format text: JAPANESE INTERMEDIATE CODE: R250

R250 Receipt of annual fees

Free format text: JAPANESE INTERMEDIATE CODE: R250