JP6196241B2 - 生物学的に活性なポリペプチドのハイスループットスクリーニング - Google Patents

生物学的に活性なポリペプチドのハイスループットスクリーニング Download PDF

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JP6196241B2
JP6196241B2 JP2014555774A JP2014555774A JP6196241B2 JP 6196241 B2 JP6196241 B2 JP 6196241B2 JP 2014555774 A JP2014555774 A JP 2014555774A JP 2014555774 A JP2014555774 A JP 2014555774A JP 6196241 B2 JP6196241 B2 JP 6196241B2
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cell
polypeptide
nucleic acid
beads
item
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JP2015506699A (ja
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ローランド グリーン，
ローランド グリーン，
ブライアン グレーザー，
ブライアン グレーザー，
イバー メイバントッソン，
イバー メイバントッソン，
キンバリー カウフマン，
キンバリー カウフマン，
マディソン グリーン，
マディソン グリーン，
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インベンラ， インコーポレイテッド
インベンラ， インコーポレイテッド
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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/10—Processes for the isolation, preparation or purification of DNA or RNA
    • C12N15/1034—Isolating an individual clone by screening libraries
    • C12N15/1075—Isolating an individual clone by screening libraries by coupling phenotype to genotype, not provided for in other groups of this subclass
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/10—Processes for the isolation, preparation or purification of DNA or RNA
    • C12N15/1034—Isolating an individual clone by screening libraries
    • C12N15/1086—Preparation or screening of expression libraries, e.g. reporter assays

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  • Genetics & Genomics (AREA)
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  • Biomedical Technology (AREA)
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  • Biochemistry (AREA)
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  • Bioinformatics & Computational Biology (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
JP2014555774A 2012-02-02 2013-02-01 生物学的に活性なポリペプチドのハイスループットスクリーニング Expired - Fee Related JP6196241B2 (ja)

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US201261594149P 2012-02-02 2012-02-02
US61/594,149 2012-02-02
PCT/US2013/024406 WO2013116698A2 (en) 2012-02-02 2013-02-01 High throughput screen for biologically active polypeptides

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JP2015506699A JP2015506699A (ja) 2015-03-05
JP2015506699A5 JP2015506699A5 (https=) 2016-03-10
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WO2013116698A2 (en) 2013-08-08
CA2861387A1 (en) 2013-08-08
EP2809783A2 (en) 2014-12-10
JP2015506699A (ja) 2015-03-05
US20150018236A1 (en) 2015-01-15
US9701959B2 (en) 2017-07-11
WO2013116698A3 (en) 2013-10-17

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