JP6159504B2 - 医薬品成分を被覆するための無溶剤混合方法 - Google Patents

医薬品成分を被覆するための無溶剤混合方法 Download PDF

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JP6159504B2
JP6159504B2 JP2015536852A JP2015536852A JP6159504B2 JP 6159504 B2 JP6159504 B2 JP 6159504B2 JP 2015536852 A JP2015536852 A JP 2015536852A JP 2015536852 A JP2015536852 A JP 2015536852A JP 6159504 B2 JP6159504 B2 JP 6159504B2
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particles
water
coating
coated
particle size
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JP2015533162A5 (cg-RX-API-DMAC7.html
JP2015533162A (ja
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デーヴ、ラジェッシュ、エヌ．
トゥー、ダニエル
カペーチェ、マックス
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ニュー ジャージー インスティチュート オブ テクノロジー
ニュー ジャージー インスティチュート オブ テクノロジー
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5005—Wall or coating material
    • A61K9/5021—Organic macromolecular compounds
    • A61K9/5036—Polysaccharides, e.g. gums, alginate; Cyclodextrin
    • A61K9/5042—Cellulose; Cellulose derivatives, e.g. phthalate or acetate succinate esters of hydroxypropyl methylcellulose
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5005—Wall or coating material
    • A61K9/5063—Compounds of unknown constitution, e.g. material from plants or animals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5073—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals having two or more different coatings optionally including drug-containing subcoatings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5089—Processes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/02—Nutrients, e.g. vitamins, minerals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Epidemiology (AREA)
  • Zoology (AREA)
  • Botany (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Hematology (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Obesity (AREA)
  • Diabetes (AREA)
  • Nutrition Science (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
JP2015536852A 2012-10-15 2013-10-09 医薬品成分を被覆するための無溶剤混合方法 Active JP6159504B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US13/651,977 US9107851B2 (en) 2012-10-15 2012-10-15 Solventless mixing process for coating pharmaceutical ingredients
US13/651,977 2012-10-15
PCT/US2013/064058 WO2014062444A1 (en) 2012-10-15 2013-10-09 Solventless mixing process for coating pharmaceutical ingredients

Publications (3)

Publication Number Publication Date
JP2015533162A JP2015533162A (ja) 2015-11-19
JP2015533162A5 JP2015533162A5 (cg-RX-API-DMAC7.html) 2016-11-17
JP6159504B2 true JP6159504B2 (ja) 2017-07-05

Family

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JP2015536852A Active JP6159504B2 (ja) 2012-10-15 2013-10-09 医薬品成分を被覆するための無溶剤混合方法

Country Status (16)

Country Link
US (1) US9107851B2 (cg-RX-API-DMAC7.html)
EP (1) EP2906205B1 (cg-RX-API-DMAC7.html)
JP (1) JP6159504B2 (cg-RX-API-DMAC7.html)
CN (1) CN104853751B (cg-RX-API-DMAC7.html)
AR (1) AR093013A1 (cg-RX-API-DMAC7.html)
BR (1) BR112015008285B1 (cg-RX-API-DMAC7.html)
CY (1) CY1121241T1 (cg-RX-API-DMAC7.html)
DK (1) DK2906205T3 (cg-RX-API-DMAC7.html)
ES (1) ES2688889T3 (cg-RX-API-DMAC7.html)
HR (1) HRP20181463T1 (cg-RX-API-DMAC7.html)
HU (1) HUE039772T2 (cg-RX-API-DMAC7.html)
PL (1) PL2906205T3 (cg-RX-API-DMAC7.html)
PT (1) PT2906205T (cg-RX-API-DMAC7.html)
RS (1) RS57918B1 (cg-RX-API-DMAC7.html)
SI (1) SI2906205T1 (cg-RX-API-DMAC7.html)
WO (1) WO2014062444A1 (cg-RX-API-DMAC7.html)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2016011412A1 (en) 2014-07-17 2016-01-21 Ada Technologies, Inc. Extreme long life, high energy density batteries and method of making and using the same
CN104587472B (zh) * 2014-12-31 2017-12-15 广东国方医药科技有限公司 一种含纳米SiO2的包衣剂及其制备方法
WO2016209460A2 (en) 2015-05-21 2016-12-29 Ada Technologies, Inc. High energy density hybrid pseudocapacitors and method of making and using the same
US12401042B2 (en) 2015-06-01 2025-08-26 Forge Nano Inc. Nano-engineered coatings for anode active materials, cathode active materials, and solid-state electrolytes and methods of making batteries containing nano-engineered coatings
US12027661B2 (en) 2015-06-01 2024-07-02 Forge Nano Inc. Nano-engineered coatings for anode active materials, cathode active materials, and solid-state electrolytes and methods of making batteries containing nano-engineered coatings
US11996564B2 (en) 2015-06-01 2024-05-28 Forge Nano Inc. Nano-engineered coatings for anode active materials, cathode active materials, and solid-state electrolytes and methods of making batteries containing nano-engineered coatings
US10692659B2 (en) 2015-07-31 2020-06-23 Ada Technologies, Inc. High energy and power electrochemical device and method of making and using same
JP7069538B2 (ja) * 2016-12-05 2022-05-18 マルボシ酢株式会社 食酢含有飲料組成物
US11024846B2 (en) 2017-03-23 2021-06-01 Ada Technologies, Inc. High energy/power density, long cycle life, safe lithium-ion battery capable of long-term deep discharge/storage near zero volt and method of making and using the same
JPWO2019009335A1 (ja) * 2017-07-04 2020-07-02 村上　正裕 微粒子の製造方法及び微粒子
AU2020223894B2 (en) * 2019-02-22 2025-09-18 Catalent U.K. Swindon Zydis Limited Minimizing agglomeration, aeration, and preserving the coating of pharmaceutical compositions comprising Ibuprofen
HUE064287T2 (hu) * 2019-02-22 2024-02-28 Catalent Uk Swindon Zydis Ltd Hatóanyagrészecske-bevonóanyag agglomerálódásának minimalizálása tárolás során, gyógyszerészeti termékek szétesési idejének stabilizálására
EP3927313B1 (en) * 2019-02-22 2025-12-24 Catalent U.K. Swindon Zydis Limited Preserving functionally-coated api particles produced by solventless mixing processes in aqueous suspension
ES2961850T3 (es) 2019-02-22 2024-03-14 Catalent Uk Swindon Zydis Ltd Minimización de la aireación de suspensiones durante la mezcla en línea
US20210009767A1 (en) * 2019-07-11 2021-01-14 International Flavors & Fragrances Inc. Solventless particle coating via acoustic mixing
US12285731B2 (en) 2019-09-12 2025-04-29 United States Of America, As Represented By The Secretary Of The Army Acoustic mixing system for creating propellant mixture
MX2023001004A (es) 2020-07-31 2023-03-01 Catalent Uk Swindon Zydis Ltd Composiciones farmaceuticas que comprenden un ingrediente farmaceutico activo (api) recubierto.

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5628945A (en) 1992-08-03 1997-05-13 Riman; Richard E. Multicomponent powder mixing process and compositions produced thereby
WO1994015374A1 (fr) * 1992-12-25 1994-07-07 Tdk Corporation Element secondaire au lithium
US5769917A (en) * 1996-12-09 1998-06-23 Belko; William C. Process for producing low shrink ceramic bodies
US6740341B1 (en) 1998-11-25 2004-05-25 Cima Labs Inc. Taste masking rapid release coating system
DE10062176A1 (de) * 2000-12-14 2002-07-04 Wacker Polymer Systems Gmbh Polyvinylacetal-gepfropfte Polymerisate
US8163114B2 (en) 2004-04-07 2012-04-24 New Jersey Institute Of Technology Netshape manufacturing processes and compositions
DE102004059792A1 (de) * 2004-12-10 2006-06-14 Röhm GmbH & Co. KG Multipartikuläre Arzneiform, enthaltend mucoadhaesiv formulierte Nukleinsäure-Wirkstoffe, sowie ein Verfahren zur Herstellung der Arzneiform
US20060210694A1 (en) * 2005-03-18 2006-09-21 Chappell Rulon A Anti-caking agents and methods
WO2007014464A1 (en) 2005-08-03 2007-02-08 The University Of Western Ontario Direct coating solid dosage forms using powdered materials
PT2570120T (pt) 2010-06-08 2018-01-09 Nippon Soda Co Partículas revestidas e processo de produção de partículas revestidas
GB201205632D0 (en) 2012-03-30 2012-05-16 Vectura Ltd Method and apparatus
US8993041B2 (en) * 2012-10-15 2015-03-31 New Jersey Institute Of Technology Taste masked active pharmaceutical powder compositions and processes for making them

Also Published As

Publication number Publication date
ES2688889T3 (es) 2018-11-07
PT2906205T (pt) 2018-11-07
CN104853751A (zh) 2015-08-19
US20140106059A1 (en) 2014-04-17
CN104853751B (zh) 2018-06-22
HUE039772T2 (hu) 2019-02-28
HRP20181463T1 (hr) 2018-12-14
PL2906205T3 (pl) 2019-03-29
BR112015008285A2 (pt) 2017-07-04
EP2906205B1 (en) 2018-06-13
SI2906205T1 (sl) 2018-12-31
US9107851B2 (en) 2015-08-18
AR093013A1 (es) 2015-05-13
JP2015533162A (ja) 2015-11-19
BR112015008285B1 (pt) 2022-11-16
CY1121241T1 (el) 2020-05-29
EP2906205A1 (en) 2015-08-19
RS57918B1 (sr) 2019-01-31
DK2906205T3 (en) 2018-09-24
WO2014062444A1 (en) 2014-04-24

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