AR093013A1 - Proceso de mezclado sin uso de solventes para el recubrimiento de ingredientes farmaceuticos - Google Patents
Proceso de mezclado sin uso de solventes para el recubrimiento de ingredientes farmaceuticosInfo
- Publication number
- AR093013A1 AR093013A1 ARP130103731A ARP130103731A AR093013A1 AR 093013 A1 AR093013 A1 AR 093013A1 AR P130103731 A ARP130103731 A AR P130103731A AR P130103731 A ARP130103731 A AR P130103731A AR 093013 A1 AR093013 A1 AR 093013A1
- Authority
- AR
- Argentina
- Prior art keywords
- particles
- polymer
- combinations
- process according
- wax
- Prior art date
Links
- 238000000034 method Methods 0.000 title abstract 5
- 238000000576 coating method Methods 0.000 title abstract 4
- 239000011248 coating agent Substances 0.000 title abstract 3
- 239000002904 solvent Substances 0.000 title abstract 3
- 239000004615 ingredient Substances 0.000 title 1
- 239000002245 particle Substances 0.000 abstract 7
- -1 polyethylene Polymers 0.000 abstract 3
- 229920000642 polymer Polymers 0.000 abstract 3
- 239000008186 active pharmaceutical agent Substances 0.000 abstract 2
- 239000000463 material Substances 0.000 abstract 2
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 abstract 2
- WCOXQTXVACYMLM-UHFFFAOYSA-N 2,3-bis(12-hydroxyoctadecanoyloxy)propyl 12-hydroxyoctadecanoate Chemical compound CCCCCCC(O)CCCCCCCCCCC(=O)OCC(OC(=O)CCCCCCCCCCC(O)CCCCCC)COC(=O)CCCCCCCCCCC(O)CCCCCC WCOXQTXVACYMLM-UHFFFAOYSA-N 0.000 abstract 1
- VGGSQFUCUMXWEO-UHFFFAOYSA-N Ethene Chemical compound C=C VGGSQFUCUMXWEO-UHFFFAOYSA-N 0.000 abstract 1
- 239000005977 Ethylene Substances 0.000 abstract 1
- 229920002153 Hydroxypropyl cellulose Polymers 0.000 abstract 1
- GUBGYTABKSRVRQ-QKKXKWKRSA-N Lactose Natural products OC[C@H]1O[C@@H](O[C@H]2[C@H](O)[C@@H](O)C(O)O[C@@H]2CO)[C@H](O)[C@@H](O)[C@H]1O GUBGYTABKSRVRQ-QKKXKWKRSA-N 0.000 abstract 1
- 239000004952 Polyamide Substances 0.000 abstract 1
- 239000004698 Polyethylene Substances 0.000 abstract 1
- 239000004743 Polypropylene Substances 0.000 abstract 1
- 238000005054 agglomeration Methods 0.000 abstract 1
- 230000002776 aggregation Effects 0.000 abstract 1
- 239000004203 carnauba wax Substances 0.000 abstract 1
- 235000013869 carnauba wax Nutrition 0.000 abstract 1
- 239000003814 drug Substances 0.000 abstract 1
- 229940079593 drug Drugs 0.000 abstract 1
- 238000001035 drying Methods 0.000 abstract 1
- 239000000796 flavoring agent Substances 0.000 abstract 1
- 235000019634 flavors Nutrition 0.000 abstract 1
- 229920001477 hydrophilic polymer Polymers 0.000 abstract 1
- 229920001600 hydrophobic polymer Polymers 0.000 abstract 1
- 239000001863 hydroxypropyl cellulose Substances 0.000 abstract 1
- 235000010977 hydroxypropyl cellulose Nutrition 0.000 abstract 1
- 239000001866 hydroxypropyl methyl cellulose Substances 0.000 abstract 1
- 235000010979 hydroxypropyl methyl cellulose Nutrition 0.000 abstract 1
- 229920003088 hydroxypropyl methyl cellulose Polymers 0.000 abstract 1
- UFVKGYZPFZQRLF-UHFFFAOYSA-N hydroxypropyl methyl cellulose Chemical compound OC1C(O)C(OC)OC(CO)C1OC1C(O)C(O)C(OC2C(C(O)C(OC3C(C(O)C(O)C(CO)O3)O)C(CO)O2)O)C(CO)O1 UFVKGYZPFZQRLF-UHFFFAOYSA-N 0.000 abstract 1
- 239000008101 lactose Substances 0.000 abstract 1
- 229920002647 polyamide Polymers 0.000 abstract 1
- 229920000573 polyethylene Polymers 0.000 abstract 1
- 229920000193 polymethacrylate Polymers 0.000 abstract 1
- 229920001155 polypropylene Polymers 0.000 abstract 1
- 229920001343 polytetrafluoroethylene Polymers 0.000 abstract 1
- 239000004810 polytetrafluoroethylene Substances 0.000 abstract 1
- 239000000843 powder Substances 0.000 abstract 1
- 230000002035 prolonged effect Effects 0.000 abstract 1
- 229920003176 water-insoluble polymer Polymers 0.000 abstract 1
- 239000001993 wax Substances 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
- A61K9/5005—Wall or coating material
- A61K9/5021—Organic macromolecular compounds
- A61K9/5036—Polysaccharides, e.g. gums, alginate; Cyclodextrin
- A61K9/5042—Cellulose; Cellulose derivatives, e.g. phthalate or acetate succinate esters of hydroxypropyl methylcellulose
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
- A61K9/5005—Wall or coating material
- A61K9/5063—Compounds of unknown constitution, e.g. material from plants or animals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
- A61K9/5073—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals having two or more different coatings optionally including drug-containing subcoatings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
- A61K9/5089—Processes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/02—Nutrients, e.g. vitamins, minerals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical & Material Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Medicinal Chemistry (AREA)
- Epidemiology (AREA)
- Zoology (AREA)
- Botany (AREA)
- Organic Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Hematology (AREA)
- Pain & Pain Management (AREA)
- Rheumatology (AREA)
- Obesity (AREA)
- Diabetes (AREA)
- Nutrition Science (AREA)
- Medicinal Preparation (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US13/651,977 US9107851B2 (en) | 2012-10-15 | 2012-10-15 | Solventless mixing process for coating pharmaceutical ingredients |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| AR093013A1 true AR093013A1 (es) | 2015-05-13 |
Family
ID=49474713
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ARP130103731A AR093013A1 (es) | 2012-10-15 | 2013-10-15 | Proceso de mezclado sin uso de solventes para el recubrimiento de ingredientes farmaceuticos |
Country Status (16)
| Country | Link |
|---|---|
| US (1) | US9107851B2 (cg-RX-API-DMAC7.html) |
| EP (1) | EP2906205B1 (cg-RX-API-DMAC7.html) |
| JP (1) | JP6159504B2 (cg-RX-API-DMAC7.html) |
| CN (1) | CN104853751B (cg-RX-API-DMAC7.html) |
| AR (1) | AR093013A1 (cg-RX-API-DMAC7.html) |
| BR (1) | BR112015008285B1 (cg-RX-API-DMAC7.html) |
| CY (1) | CY1121241T1 (cg-RX-API-DMAC7.html) |
| DK (1) | DK2906205T3 (cg-RX-API-DMAC7.html) |
| ES (1) | ES2688889T3 (cg-RX-API-DMAC7.html) |
| HR (1) | HRP20181463T1 (cg-RX-API-DMAC7.html) |
| HU (1) | HUE039772T2 (cg-RX-API-DMAC7.html) |
| PL (1) | PL2906205T3 (cg-RX-API-DMAC7.html) |
| PT (1) | PT2906205T (cg-RX-API-DMAC7.html) |
| RS (1) | RS57918B1 (cg-RX-API-DMAC7.html) |
| SI (1) | SI2906205T1 (cg-RX-API-DMAC7.html) |
| WO (1) | WO2014062444A1 (cg-RX-API-DMAC7.html) |
Families Citing this family (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2016011412A1 (en) | 2014-07-17 | 2016-01-21 | Ada Technologies, Inc. | Extreme long life, high energy density batteries and method of making and using the same |
| CN104587472B (zh) * | 2014-12-31 | 2017-12-15 | 广东国方医药科技有限公司 | 一种含纳米SiO2的包衣剂及其制备方法 |
| WO2016209460A2 (en) | 2015-05-21 | 2016-12-29 | Ada Technologies, Inc. | High energy density hybrid pseudocapacitors and method of making and using the same |
| US12401042B2 (en) | 2015-06-01 | 2025-08-26 | Forge Nano Inc. | Nano-engineered coatings for anode active materials, cathode active materials, and solid-state electrolytes and methods of making batteries containing nano-engineered coatings |
| US12027661B2 (en) | 2015-06-01 | 2024-07-02 | Forge Nano Inc. | Nano-engineered coatings for anode active materials, cathode active materials, and solid-state electrolytes and methods of making batteries containing nano-engineered coatings |
| US11996564B2 (en) | 2015-06-01 | 2024-05-28 | Forge Nano Inc. | Nano-engineered coatings for anode active materials, cathode active materials, and solid-state electrolytes and methods of making batteries containing nano-engineered coatings |
| US10692659B2 (en) | 2015-07-31 | 2020-06-23 | Ada Technologies, Inc. | High energy and power electrochemical device and method of making and using same |
| JP7069538B2 (ja) * | 2016-12-05 | 2022-05-18 | マルボシ酢株式会社 | 食酢含有飲料組成物 |
| US11024846B2 (en) | 2017-03-23 | 2021-06-01 | Ada Technologies, Inc. | High energy/power density, long cycle life, safe lithium-ion battery capable of long-term deep discharge/storage near zero volt and method of making and using the same |
| JPWO2019009335A1 (ja) * | 2017-07-04 | 2020-07-02 | 村上 正裕 | 微粒子の製造方法及び微粒子 |
| AU2020223894B2 (en) * | 2019-02-22 | 2025-09-18 | Catalent U.K. Swindon Zydis Limited | Minimizing agglomeration, aeration, and preserving the coating of pharmaceutical compositions comprising Ibuprofen |
| HUE064287T2 (hu) * | 2019-02-22 | 2024-02-28 | Catalent Uk Swindon Zydis Ltd | Hatóanyagrészecske-bevonóanyag agglomerálódásának minimalizálása tárolás során, gyógyszerészeti termékek szétesési idejének stabilizálására |
| EP3927313B1 (en) * | 2019-02-22 | 2025-12-24 | Catalent U.K. Swindon Zydis Limited | Preserving functionally-coated api particles produced by solventless mixing processes in aqueous suspension |
| ES2961850T3 (es) | 2019-02-22 | 2024-03-14 | Catalent Uk Swindon Zydis Ltd | Minimización de la aireación de suspensiones durante la mezcla en línea |
| US20210009767A1 (en) * | 2019-07-11 | 2021-01-14 | International Flavors & Fragrances Inc. | Solventless particle coating via acoustic mixing |
| US12285731B2 (en) | 2019-09-12 | 2025-04-29 | United States Of America, As Represented By The Secretary Of The Army | Acoustic mixing system for creating propellant mixture |
| MX2023001004A (es) | 2020-07-31 | 2023-03-01 | Catalent Uk Swindon Zydis Ltd | Composiciones farmaceuticas que comprenden un ingrediente farmaceutico activo (api) recubierto. |
Family Cites Families (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5628945A (en) | 1992-08-03 | 1997-05-13 | Riman; Richard E. | Multicomponent powder mixing process and compositions produced thereby |
| WO1994015374A1 (fr) * | 1992-12-25 | 1994-07-07 | Tdk Corporation | Element secondaire au lithium |
| US5769917A (en) * | 1996-12-09 | 1998-06-23 | Belko; William C. | Process for producing low shrink ceramic bodies |
| US6740341B1 (en) | 1998-11-25 | 2004-05-25 | Cima Labs Inc. | Taste masking rapid release coating system |
| DE10062176A1 (de) * | 2000-12-14 | 2002-07-04 | Wacker Polymer Systems Gmbh | Polyvinylacetal-gepfropfte Polymerisate |
| US8163114B2 (en) | 2004-04-07 | 2012-04-24 | New Jersey Institute Of Technology | Netshape manufacturing processes and compositions |
| DE102004059792A1 (de) * | 2004-12-10 | 2006-06-14 | Röhm GmbH & Co. KG | Multipartikuläre Arzneiform, enthaltend mucoadhaesiv formulierte Nukleinsäure-Wirkstoffe, sowie ein Verfahren zur Herstellung der Arzneiform |
| US20060210694A1 (en) * | 2005-03-18 | 2006-09-21 | Chappell Rulon A | Anti-caking agents and methods |
| WO2007014464A1 (en) | 2005-08-03 | 2007-02-08 | The University Of Western Ontario | Direct coating solid dosage forms using powdered materials |
| PT2570120T (pt) | 2010-06-08 | 2018-01-09 | Nippon Soda Co | Partículas revestidas e processo de produção de partículas revestidas |
| GB201205632D0 (en) | 2012-03-30 | 2012-05-16 | Vectura Ltd | Method and apparatus |
| US8993041B2 (en) * | 2012-10-15 | 2015-03-31 | New Jersey Institute Of Technology | Taste masked active pharmaceutical powder compositions and processes for making them |
-
2012
- 2012-10-15 US US13/651,977 patent/US9107851B2/en active Active
-
2013
- 2013-10-09 CN CN201380053927.5A patent/CN104853751B/zh active Active
- 2013-10-09 BR BR112015008285-8A patent/BR112015008285B1/pt active IP Right Grant
- 2013-10-09 SI SI201331167T patent/SI2906205T1/sl unknown
- 2013-10-09 ES ES13780276.5T patent/ES2688889T3/es active Active
- 2013-10-09 HU HUE13780276A patent/HUE039772T2/hu unknown
- 2013-10-09 HR HRP20181463TT patent/HRP20181463T1/hr unknown
- 2013-10-09 PL PL13780276T patent/PL2906205T3/pl unknown
- 2013-10-09 PT PT13780276T patent/PT2906205T/pt unknown
- 2013-10-09 JP JP2015536852A patent/JP6159504B2/ja active Active
- 2013-10-09 RS RS20181079A patent/RS57918B1/sr unknown
- 2013-10-09 DK DK13780276.5T patent/DK2906205T3/en active
- 2013-10-09 EP EP13780276.5A patent/EP2906205B1/en active Active
- 2013-10-09 WO PCT/US2013/064058 patent/WO2014062444A1/en not_active Ceased
- 2013-10-15 AR ARP130103731A patent/AR093013A1/es not_active Application Discontinuation
-
2018
- 2018-09-13 CY CY20181100951T patent/CY1121241T1/el unknown
Also Published As
| Publication number | Publication date |
|---|---|
| ES2688889T3 (es) | 2018-11-07 |
| PT2906205T (pt) | 2018-11-07 |
| JP6159504B2 (ja) | 2017-07-05 |
| CN104853751A (zh) | 2015-08-19 |
| US20140106059A1 (en) | 2014-04-17 |
| CN104853751B (zh) | 2018-06-22 |
| HUE039772T2 (hu) | 2019-02-28 |
| HRP20181463T1 (hr) | 2018-12-14 |
| PL2906205T3 (pl) | 2019-03-29 |
| BR112015008285A2 (pt) | 2017-07-04 |
| EP2906205B1 (en) | 2018-06-13 |
| SI2906205T1 (sl) | 2018-12-31 |
| US9107851B2 (en) | 2015-08-18 |
| JP2015533162A (ja) | 2015-11-19 |
| BR112015008285B1 (pt) | 2022-11-16 |
| CY1121241T1 (el) | 2020-05-29 |
| EP2906205A1 (en) | 2015-08-19 |
| RS57918B1 (sr) | 2019-01-31 |
| DK2906205T3 (en) | 2018-09-24 |
| WO2014062444A1 (en) | 2014-04-24 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| AR093013A1 (es) | Proceso de mezclado sin uso de solventes para el recubrimiento de ingredientes farmaceuticos | |
| Anjani et al. | Elucidating the impact of surfactants on the performance of dissolving microneedle array patches | |
| Maleki et al. | Mesoporous silica materials: From physico-chemical properties to enhanced dissolution of poorly water-soluble drugs | |
| Buwalda et al. | Hydrogels in a historical perspective: From simple networks to smart materials | |
| EP4218724A3 (en) | Microstructure array for delivery of active agents | |
| CN104383609B (zh) | 一种可调控细胞粘附的材料在筛选内皮细胞和平滑肌细胞中的应用 | |
| Mundargi et al. | Encapsulation and controlled release formulations of 5-fluorouracil from natural Lycopodium clavatum spores | |
| RU2015129771A (ru) | Микроматрица для доставки терапевтического средства и способы использования | |
| Ghanbar et al. | Preparation of porous microsphere-scaffolds by electrohydrodynamic forming and thermally induced phase separation | |
| RU2014145442A (ru) | Постобработка медицинского устройства для регулирования морфологии и механических свойств | |
| MX387477B (es) | Formulaciones de depósito. | |
| AR093012A1 (es) | Composiciones farmaceuticas en polvo, activas, con enmascaramiento del sabor y procesos para su fabricacion | |
| UY38673A (es) | Producto farmacéutico combinado que contiene leuprolido, un polímero biodegradable y gnrh o agonista | |
| Agnello et al. | Microfluidic production of hyaluronic acid derivative microfibers to control drug release | |
| JP2018510204A (ja) | 薬物の生分解性ポリマー内における均質化システム：スマートポリマーシステム | |
| Mukai et al. | PET imaging with macro-and middle-sized molecular probes | |
| KR101703050B1 (ko) | 경피전달용 미세돌기 구조체 | |
| Shen et al. | Mesoporous materials and technologies for development of oral medicine | |
| WO2017123315A3 (en) | Nanocrystals formed in a microenvironment | |
| JP2016518358A5 (cg-RX-API-DMAC7.html) | ||
| EA201990127A1 (ru) | Депо-препарат | |
| US20110256231A1 (en) | Method for preparing a micro-particle drug in hemisphere-shaped dosage form and applications thereof | |
| AU2020367398B2 (en) | Microsphere-drug combination | |
| US12514931B2 (en) | Microsphere-drug combination | |
| Dang et al. | Microfluidic Encapsulation of Vorinostat in Calcium Alginate Microparticles: Prolonged Release and Enhanced in vitro Cytotoxicity |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FC | Refusal |