BR112015008285A2 - processo para preparar uma formulação farmacêutica particulada - Google Patents
processo para preparar uma formulação farmacêutica particuladaInfo
- Publication number
- BR112015008285A2 BR112015008285A2 BR112015008285A BR112015008285A BR112015008285A2 BR 112015008285 A2 BR112015008285 A2 BR 112015008285A2 BR 112015008285 A BR112015008285 A BR 112015008285A BR 112015008285 A BR112015008285 A BR 112015008285A BR 112015008285 A2 BR112015008285 A2 BR 112015008285A2
- Authority
- BR
- Brazil
- Prior art keywords
- particles
- preparing
- particulate pharmaceutical
- pharmaceutical formulation
- solvent
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
- A61K9/5005—Wall or coating material
- A61K9/5021—Organic macromolecular compounds
- A61K9/5036—Polysaccharides, e.g. gums, alginate; Cyclodextrin
- A61K9/5042—Cellulose; Cellulose derivatives, e.g. phthalate or acetate succinate esters of hydroxypropyl methylcellulose
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
- A61K9/5005—Wall or coating material
- A61K9/5063—Compounds of unknown constitution, e.g. material from plants or animals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
- A61K9/5073—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals having two or more different coatings optionally including drug-containing subcoatings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
- A61K9/5089—Processes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/02—Nutrients, e.g. vitamins, minerals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical & Material Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Medicinal Chemistry (AREA)
- Epidemiology (AREA)
- Botany (AREA)
- Zoology (AREA)
- Organic Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Hematology (AREA)
- Pain & Pain Management (AREA)
- Rheumatology (AREA)
- Obesity (AREA)
- Diabetes (AREA)
- Nutrition Science (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Abstract
1 / 1 resumo âprocesso para preparar uma formulaãão farmacãutica particuladaâ a presente invenã§ã£o ã© um mã©todo sem solvente para produzir ingrediente farmaceuticamente ativo revestido com polãmero que tem o sabor mascarado e pode ser liberado em um tempo relativamente curto. o processo emprega vibraã§ãµes de alta energia ou misturaã§ã£o acãºstica de partãculas api, partãculas de material de revestimento solãºveis em ã¡gua e partãculas de polãmero hidrofã³bico, com ou sem o uso de outros pã³s farmaceuticamente relevantes como meio. adicionalmente o mã©todo ã© capaz de produzir partãculas de droga revestidas individualmente sem aglomeraã§ã£o ou os longos tempos de secagem associados com mã©todos de revestimento com base em solvente.
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US13/651,977 US9107851B2 (en) | 2012-10-15 | 2012-10-15 | Solventless mixing process for coating pharmaceutical ingredients |
US13/651,977 | 2012-10-15 | ||
PCT/US2013/064058 WO2014062444A1 (en) | 2012-10-15 | 2013-10-09 | Solventless mixing process for coating pharmaceutical ingredients |
Publications (2)
Publication Number | Publication Date |
---|---|
BR112015008285A2 true BR112015008285A2 (pt) | 2017-07-04 |
BR112015008285B1 BR112015008285B1 (pt) | 2022-11-16 |
Family
ID=49474713
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
BR112015008285-8A BR112015008285B1 (pt) | 2012-10-15 | 2013-10-09 | Processo para preparar uma formulação farmacêutica particulada |
Country Status (16)
Country | Link |
---|---|
US (1) | US9107851B2 (pt) |
EP (1) | EP2906205B1 (pt) |
JP (1) | JP6159504B2 (pt) |
CN (1) | CN104853751B (pt) |
AR (1) | AR093013A1 (pt) |
BR (1) | BR112015008285B1 (pt) |
CY (1) | CY1121241T1 (pt) |
DK (1) | DK2906205T3 (pt) |
ES (1) | ES2688889T3 (pt) |
HR (1) | HRP20181463T1 (pt) |
HU (1) | HUE039772T2 (pt) |
PL (1) | PL2906205T3 (pt) |
PT (1) | PT2906205T (pt) |
RS (1) | RS57918B1 (pt) |
SI (1) | SI2906205T1 (pt) |
WO (1) | WO2014062444A1 (pt) |
Families Citing this family (13)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US9755235B2 (en) | 2014-07-17 | 2017-09-05 | Ada Technologies, Inc. | Extreme long life, high energy density batteries and method of making and using the same |
CN104587472B (zh) * | 2014-12-31 | 2017-12-15 | 广东国方医药科技有限公司 | 一种含纳米SiO2的包衣剂及其制备方法 |
US10217571B2 (en) | 2015-05-21 | 2019-02-26 | Ada Technologies, Inc. | High energy density hybrid pseudocapacitors and method of making and using the same |
US11996564B2 (en) | 2015-06-01 | 2024-05-28 | Forge Nano Inc. | Nano-engineered coatings for anode active materials, cathode active materials, and solid-state electrolytes and methods of making batteries containing nano-engineered coatings |
WO2017023797A1 (en) | 2015-07-31 | 2017-02-09 | Ada Technologies, Inc. | High energy and power electrochemical device and method of making and using same |
JP7069538B2 (ja) * | 2016-12-05 | 2022-05-18 | マルボシ酢株式会社 | 食酢含有飲料組成物 |
US11024846B2 (en) | 2017-03-23 | 2021-06-01 | Ada Technologies, Inc. | High energy/power density, long cycle life, safe lithium-ion battery capable of long-term deep discharge/storage near zero volt and method of making and using the same |
WO2019009335A1 (ja) * | 2017-07-04 | 2019-01-10 | 村上 正裕 | 微粒子の製造方法及び微粒子 |
AU2020225818A1 (en) | 2019-02-22 | 2021-10-14 | Catalent U.K. Swindon Zydis Limited | Preserving functionally-coated API particles produced by solventless mixing processes in aqueous suspension |
EP3927314B1 (en) * | 2019-02-22 | 2023-08-23 | Catalent U.K. Swindon Zydis Limited | Minimizing agglomeration of drug particle coating material during storage to stabilize disintegration times of pharmaceutical products |
CA3129395A1 (en) | 2019-02-22 | 2020-08-27 | Catalent U.K. Swindon Zydis Limited | Minimizing agglomeration, aeration, and preserving the coating of pharmaceutical compositions comprising ibuprofen |
US20210009767A1 (en) * | 2019-07-11 | 2021-01-14 | International Flavors & Fragrances Inc. | Solventless particle coating via acoustic mixing |
MX2023001004A (es) * | 2020-07-31 | 2023-03-01 | Catalent Uk Swindon Zydis Ltd | Composiciones farmaceuticas que comprenden un ingrediente farmaceutico activo (api) recubierto. |
Family Cites Families (12)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5628945A (en) | 1992-08-03 | 1997-05-13 | Riman; Richard E. | Multicomponent powder mixing process and compositions produced thereby |
WO1994015374A1 (en) * | 1992-12-25 | 1994-07-07 | Tdk Corporation | Lithium secondary cell |
US5769917A (en) * | 1996-12-09 | 1998-06-23 | Belko; William C. | Process for producing low shrink ceramic bodies |
US6740341B1 (en) | 1998-11-25 | 2004-05-25 | Cima Labs Inc. | Taste masking rapid release coating system |
DE10062176A1 (de) * | 2000-12-14 | 2002-07-04 | Wacker Polymer Systems Gmbh | Polyvinylacetal-gepfropfte Polymerisate |
US8163114B2 (en) | 2004-04-07 | 2012-04-24 | New Jersey Institute Of Technology | Netshape manufacturing processes and compositions |
DE102004059792A1 (de) * | 2004-12-10 | 2006-06-14 | Röhm GmbH & Co. KG | Multipartikuläre Arzneiform, enthaltend mucoadhaesiv formulierte Nukleinsäure-Wirkstoffe, sowie ein Verfahren zur Herstellung der Arzneiform |
US20060210694A1 (en) * | 2005-03-18 | 2006-09-21 | Chappell Rulon A | Anti-caking agents and methods |
CA2617190C (en) | 2005-08-03 | 2017-07-18 | The University Of Western Ontario | Direct coating solid dosage forms using powdered materials |
EP2570120B1 (en) | 2010-06-08 | 2017-10-25 | Kobe Gakuin Educational Foundation | Coated particle and method for producing coated particle |
GB201205632D0 (en) | 2012-03-30 | 2012-05-16 | Vectura Ltd | Method and apparatus |
US8993041B2 (en) * | 2012-10-15 | 2015-03-31 | New Jersey Institute Of Technology | Taste masked active pharmaceutical powder compositions and processes for making them |
-
2012
- 2012-10-15 US US13/651,977 patent/US9107851B2/en active Active
-
2013
- 2013-10-09 RS RS20181079A patent/RS57918B1/sr unknown
- 2013-10-09 ES ES13780276.5T patent/ES2688889T3/es active Active
- 2013-10-09 PL PL13780276T patent/PL2906205T3/pl unknown
- 2013-10-09 PT PT13780276T patent/PT2906205T/pt unknown
- 2013-10-09 HU HUE13780276A patent/HUE039772T2/hu unknown
- 2013-10-09 WO PCT/US2013/064058 patent/WO2014062444A1/en active Application Filing
- 2013-10-09 DK DK13780276.5T patent/DK2906205T3/en active
- 2013-10-09 BR BR112015008285-8A patent/BR112015008285B1/pt active IP Right Grant
- 2013-10-09 SI SI201331167T patent/SI2906205T1/sl unknown
- 2013-10-09 CN CN201380053927.5A patent/CN104853751B/zh active Active
- 2013-10-09 JP JP2015536852A patent/JP6159504B2/ja active Active
- 2013-10-09 EP EP13780276.5A patent/EP2906205B1/en active Active
- 2013-10-15 AR ARP130103731A patent/AR093013A1/es not_active Application Discontinuation
-
2018
- 2018-09-13 HR HRP20181463TT patent/HRP20181463T1/hr unknown
- 2018-09-13 CY CY20181100951T patent/CY1121241T1/el unknown
Also Published As
Publication number | Publication date |
---|---|
AR093013A1 (es) | 2015-05-13 |
SI2906205T1 (sl) | 2018-12-31 |
PT2906205T (pt) | 2018-11-07 |
JP6159504B2 (ja) | 2017-07-05 |
BR112015008285B1 (pt) | 2022-11-16 |
DK2906205T3 (en) | 2018-09-24 |
WO2014062444A1 (en) | 2014-04-24 |
ES2688889T3 (es) | 2018-11-07 |
US9107851B2 (en) | 2015-08-18 |
HUE039772T2 (hu) | 2019-02-28 |
US20140106059A1 (en) | 2014-04-17 |
CY1121241T1 (el) | 2020-05-29 |
JP2015533162A (ja) | 2015-11-19 |
EP2906205B1 (en) | 2018-06-13 |
HRP20181463T1 (hr) | 2018-12-14 |
RS57918B1 (sr) | 2019-01-31 |
EP2906205A1 (en) | 2015-08-19 |
CN104853751A (zh) | 2015-08-19 |
PL2906205T3 (pl) | 2019-03-29 |
CN104853751B (zh) | 2018-06-22 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
B07D | Technical examination (opinion) related to article 229 of industrial property law [chapter 7.4 patent gazette] | ||
B06F | Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette] | ||
B06F | Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette] | ||
B06I | Publication of requirement cancelled [chapter 6.9 patent gazette] |
Free format text: ANULADA A PUBLICACAO CODIGO 6.6.1 NA RPI NO 2462 DE 13/03/2018 POR TER SIDO INDEVIDA. |
|
B07E | Notification of approval relating to section 229 industrial property law [chapter 7.5 patent gazette] |
Free format text: NOTIFICACAO DE ANUENCIA RELACIONADA COM O ART 229 DA LPI |
|
B06U | Preliminary requirement: requests with searches performed by other patent offices: procedure suspended [chapter 6.21 patent gazette] | ||
B06A | Patent application procedure suspended [chapter 6.1 patent gazette] | ||
B09A | Decision: intention to grant [chapter 9.1 patent gazette] | ||
B16A | Patent or certificate of addition of invention granted [chapter 16.1 patent gazette] |
Free format text: PRAZO DE VALIDADE: 20 (VINTE) ANOS CONTADOS A PARTIR DE 09/10/2013, OBSERVADAS AS CONDICOES LEGAIS |