JP6124417B2 - 抗癌剤に起因する末梢性神経障害性疼痛の予防及び／又は治療剤 - Google Patents

抗癌剤に起因する末梢性神経障害性疼痛の予防及び／又は治療剤 Download PDF

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JP6124417B2
JP6124417B2 JP2014518384A JP2014518384A JP6124417B2 JP 6124417 B2 JP6124417 B2 JP 6124417B2 JP 2014518384 A JP2014518384 A JP 2014518384A JP 2014518384 A JP2014518384 A JP 2014518384A JP 6124417 B2 JP6124417 B2 JP 6124417B2
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thrombomodulin
cancer
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amino acid
administration
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JPWO2013179910A1 (ja
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川畑　篤史
篤史 川畑
鈴木　秀明
秀明 鈴木
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Asahi Kasei Pharma Corp
Kindai University
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Kindai University
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/36—Blood coagulation or fibrinolysis factors
    • A61K38/366—Thrombomodulin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/55—Protease inhibitors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/337—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having four-membered rings, e.g. taxol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00—Drugs for disorders of the muscular or neuromuscular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/02—Antineoplastic agents specific for leukemia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/745—Blood coagulation or fibrinolysis factors
    • C07K14/7455—Thrombomodulin

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Organic Chemistry (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Zoology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Hematology (AREA)
  • Immunology (AREA)
  • Biophysics (AREA)
  • Toxicology (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Neurology (AREA)
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  • Biomedical Technology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Pain & Pain Management (AREA)
  • Oncology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Peptides Or Proteins (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
JP2014518384A 2012-05-31 2013-05-17 抗癌剤に起因する末梢性神経障害性疼痛の予防及び／又は治療剤 Active JP6124417B2 (ja)

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JP2014518384A JP6124417B2 (ja) 2012-05-31 2013-05-17 抗癌剤に起因する末梢性神経障害性疼痛の予防及び／又は治療剤

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JP2012125316 2012-05-31
JP2012125316 2012-05-31
PCT/JP2013/063743 WO2013179910A1 (ja) 2012-05-31 2013-05-17 抗癌剤に起因する末梢性神経障害性疼痛の予防及び／又は治療剤
JP2014518384A JP6124417B2 (ja) 2012-05-31 2013-05-17 抗癌剤に起因する末梢性神経障害性疼痛の予防及び／又は治療剤

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JP6124417B2 true JP6124417B2 (ja) 2017-05-10

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JP2017071200A Active JP6279788B2 (ja) 2012-05-31 2017-03-31 抗癌剤に起因する末梢性神経障害性疼痛の予防及び／又は治療剤
JP2018005582A Active JP6427284B2 (ja) 2012-05-31 2018-01-17 抗癌剤に起因する末梢性神経障害性疼痛の予防及び／又は治療剤

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JP2018005582A Active JP6427284B2 (ja) 2012-05-31 2018-01-17 抗癌剤に起因する末梢性神経障害性疼痛の予防及び／又は治療剤

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KR (1) KR101672114B1 (enExample)
CN (1) CN104394885B (enExample)
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HU (1) HUE045997T2 (enExample)
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IN (1) IN2014DN10075A (enExample)
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NZ (1) NZ702242A (enExample)
PL (1) PL2857037T3 (enExample)
PT (1) PT2857037T (enExample)
RU (1) RU2595857C2 (enExample)
WO (1) WO2013179910A1 (enExample)
ZA (1) ZA201408769B (enExample)

Cited By (2)

* Cited by examiner, † Cited by third party
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JP2017141268A (ja) * 2012-05-31 2017-08-17 学校法人近畿大学 抗癌剤に起因する末梢性神経障害性疼痛の予防及び／又は治療剤
US11497795B2 (en) 2018-09-28 2022-11-15 Asahi Kasei Pharma Corporation Medicament for mitigating conditions and/or suppressing onset of peripheral neuropathy induced by anti-malignant tumor agent

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MX394717B (es) * 2017-03-31 2025-03-24 Toray Industries Agente terapeutico o profilactico para neuropatias perifericas.
EP3727367A4 (en) * 2017-12-19 2021-10-27 Synergia Life Sciences Pvt. Ltd VITAMIN K2 COMPOSITIONS FOR THE TREATMENT OF DRUG-INDUCED NEUROPATHY
AU2019347406B9 (en) * 2018-09-28 2023-11-16 Asahi Kasei Pharma Corporation Medicament for mitigating conditions and/or suppressing onset of peripheral neuropathy induced by anti-malignant tumor agent
RU2707954C1 (ru) * 2019-01-24 2019-12-02 Федеральное государственное бюджетное учреждение "Ростовский научно-исследовательский онкологический институт" Министерства здравоохранения Российской Федерации Способ лечения онкологической боли

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Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2017141268A (ja) * 2012-05-31 2017-08-17 学校法人近畿大学 抗癌剤に起因する末梢性神経障害性疼痛の予防及び／又は治療剤
JP2018095652A (ja) * 2012-05-31 2018-06-21 学校法人近畿大学 抗癌剤に起因する末梢性神経障害性疼痛の予防及び／又は治療剤
US10709767B2 (en) 2012-05-31 2020-07-14 Kinki University Agent for prophylactic and/or therapeutic treatment of peripheral neuropathic pain caused by anticancer agent
US11497795B2 (en) 2018-09-28 2022-11-15 Asahi Kasei Pharma Corporation Medicament for mitigating conditions and/or suppressing onset of peripheral neuropathy induced by anti-malignant tumor agent

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PL2857037T3 (pl) 2019-12-31
JP2018095652A (ja) 2018-06-21
HK1203846A1 (en) 2015-11-06
WO2013179910A1 (ja) 2013-12-05
AU2013268725A1 (en) 2014-12-18
CN104394885A (zh) 2015-03-04
ZA201408769B (en) 2015-12-23
AU2013268725B2 (en) 2017-02-16
NZ702242A (en) 2016-03-31
MX364934B (es) 2019-03-28
CN104394885B (zh) 2017-06-30
IL235984A0 (en) 2015-01-29
DK2857037T3 (da) 2019-07-22
KR20150004855A (ko) 2015-01-13
KR101672114B1 (ko) 2016-11-02
JP6427284B2 (ja) 2018-11-21
US20150148296A1 (en) 2015-05-28
BR112014028852A2 (pt) 2018-04-24
CA2875069C (en) 2018-01-02
JPWO2013179910A1 (ja) 2016-01-18
MX2014014505A (es) 2015-06-02
PT2857037T (pt) 2019-07-19
ES2743767T3 (es) 2020-02-20
HUE045997T2 (hu) 2020-01-28
RU2595857C2 (ru) 2016-08-27
EP2857037A1 (en) 2015-04-08
CA2875069A1 (en) 2013-12-05
RU2014148171A (ru) 2016-07-20
EP2857037A4 (en) 2016-04-06
IL235984B (en) 2019-09-26
US10709767B2 (en) 2020-07-14
IN2014DN10075A (enExample) 2015-08-21
EP2857037B1 (en) 2019-06-26
JP6279788B2 (ja) 2018-02-14
JP2017141268A (ja) 2017-08-17

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