CA2875069C - Agent for prophylactic and/or therapeutic treatment of peripheral neuropathic pain caused by anticancer agent - Google Patents
Agent for prophylactic and/or therapeutic treatment of peripheral neuropathic pain caused by anticancer agent Download PDFInfo
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- CA2875069C CA2875069C CA2875069A CA2875069A CA2875069C CA 2875069 C CA2875069 C CA 2875069C CA 2875069 A CA2875069 A CA 2875069A CA 2875069 A CA2875069 A CA 2875069A CA 2875069 C CA2875069 C CA 2875069C
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- 230000000144 pharmacologic effect Effects 0.000 description 1
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- 208000028591 pheochromocytoma Diseases 0.000 description 1
- 239000013612 plasmid Substances 0.000 description 1
- ONJQDTZCDSESIW-UHFFFAOYSA-N polidocanol Chemical compound CCCCCCCCCCCCOCCOCCOCCOCCOCCOCCOCCOCCOCCO ONJQDTZCDSESIW-UHFFFAOYSA-N 0.000 description 1
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Classifications
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- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/36—Blood coagulation or fibrinolysis factors
- A61K38/366—Thrombomodulin
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- A—HUMAN NECESSITIES
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- A61K38/55—Protease inhibitors
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- A—HUMAN NECESSITIES
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/337—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having four-membered rings, e.g. taxol
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- A—HUMAN NECESSITIES
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- A—HUMAN NECESSITIES
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- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
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- A—HUMAN NECESSITIES
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- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
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- A—HUMAN NECESSITIES
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
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- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/02—Antineoplastic agents specific for leukemia
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/745—Blood coagulation or fibrinolysis factors
- C07K14/7455—Thrombomodulin
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Organic Chemistry (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Gastroenterology & Hepatology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Zoology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
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- Genetics & Genomics (AREA)
- Toxicology (AREA)
- Molecular Biology (AREA)
- Biophysics (AREA)
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- Neurology (AREA)
- Biomedical Technology (AREA)
- Neurosurgery (AREA)
- Pain & Pain Management (AREA)
- Physical Education & Sports Medicine (AREA)
- Oncology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Peptides Or Proteins (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2012125316 | 2012-05-31 | ||
| JP2012-125316 | 2012-05-31 | ||
| PCT/JP2013/063743 WO2013179910A1 (ja) | 2012-05-31 | 2013-05-17 | 抗癌剤に起因する末梢性神経障害性疼痛の予防及び／又は治療剤 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CA2875069A1 CA2875069A1 (en) | 2013-12-05 |
| CA2875069C true CA2875069C (en) | 2018-01-02 |
Family
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Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA2875069A Active CA2875069C (en) | 2012-05-31 | 2013-05-17 | Agent for prophylactic and/or therapeutic treatment of peripheral neuropathic pain caused by anticancer agent |
Country Status (20)
| Country | Link |
|---|---|
| US (1) | US10709767B2 (enExample) |
| EP (1) | EP2857037B1 (enExample) |
| JP (3) | JP6124417B2 (enExample) |
| KR (1) | KR101672114B1 (enExample) |
| CN (1) | CN104394885B (enExample) |
| AU (1) | AU2013268725B2 (enExample) |
| BR (1) | BR112014028852A2 (enExample) |
| CA (1) | CA2875069C (enExample) |
| DK (1) | DK2857037T3 (enExample) |
| ES (1) | ES2743767T3 (enExample) |
| HU (1) | HUE045997T2 (enExample) |
| IL (1) | IL235984B (enExample) |
| IN (1) | IN2014DN10075A (enExample) |
| MX (1) | MX364934B (enExample) |
| NZ (1) | NZ702242A (enExample) |
| PL (1) | PL2857037T3 (enExample) |
| PT (1) | PT2857037T (enExample) |
| RU (1) | RU2595857C2 (enExample) |
| WO (1) | WO2013179910A1 (enExample) |
| ZA (1) | ZA201408769B (enExample) |
Families Citing this family (8)
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| US10709767B2 (en) * | 2012-05-31 | 2020-07-14 | Kinki University | Agent for prophylactic and/or therapeutic treatment of peripheral neuropathic pain caused by anticancer agent |
| JP6325036B2 (ja) * | 2016-08-19 | 2018-05-16 | 株式会社明治 | 抗がん剤に起因する末梢神経障害を改善するための組成物 |
| IL269502B (en) * | 2017-03-31 | 2022-09-01 | Toray Industries | A therapeutic or preventive factor for peripheral neuropathies |
| WO2019123144A1 (en) * | 2017-12-19 | 2019-06-27 | Synergia Life Sciences Pvt. Ltd. | Vitamin k2 compositions for the treatment of drug induced neuropathy |
| WO2020067389A1 (ja) | 2018-09-28 | 2020-04-02 | 旭化成ファーマ株式会社 | 抗悪性腫瘍剤による末梢神経障害の症状軽減及び／又は発症抑制のための医薬 |
| US11497795B2 (en) | 2018-09-28 | 2022-11-15 | Asahi Kasei Pharma Corporation | Medicament for mitigating conditions and/or suppressing onset of peripheral neuropathy induced by anti-malignant tumor agent |
| RU2707954C1 (ru) * | 2019-01-24 | 2019-12-02 | Федеральное государственное бюджетное учреждение "Ростовский научно-исследовательский онкологический институт" Министерства здравоохранения Российской Федерации | Способ лечения онкологической боли |
| AU2022226352A1 (en) * | 2021-02-26 | 2023-09-07 | Vibrosense Dynamics Ab | Biomarker for prediction of chemotherapy-induced neuropathy |
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| EP0312598B1 (en) | 1987-01-08 | 1999-05-26 | Asahi Kasei Kogyo Kabushiki Kaisha | Peptide functioning to accelerate activation of protein c with thrombin |
| DE3876124T2 (de) | 1987-04-01 | 1993-05-06 | Mitsubishi Gas Chemical Co | Immunoassay fuer thrombomodulin. |
| DK299087D0 (da) | 1987-06-12 | 1987-06-12 | Novo Industri As | Proteins and derivatives thereof |
| JPS6445398A (en) | 1987-08-13 | 1989-02-17 | Kowa Co | Antithrombin-binding substance monoclonal antibody, hybridoma producing said antibody and method for purifying and measuring thrombin-binding substance utilizing said monoclonal antibody |
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| JPH02255699A (ja) | 1989-03-28 | 1990-10-16 | Asahi Chem Ind Co Ltd | 新規血液抗凝固物質及びその製法 |
| AU643306B2 (en) | 1990-06-27 | 1993-11-11 | Mochida Pharmaceutical Co., Ltd. | Anticoagulant polypeptides |
| JPH05213998A (ja) | 1990-08-03 | 1993-08-24 | Asahi Chem Ind Co Ltd | 新規なポリペプチド及びこれを有効成分とする 医薬組成物 |
| US5571786A (en) | 1990-08-16 | 1996-11-05 | Immuno Aktiengesellschaft | Use of protein C or the activation peptide of protein C for preparing a pharmaceutical preparation |
| JPH05310787A (ja) | 1992-05-01 | 1993-11-22 | Asahi Chem Ind Co Ltd | 新規なポリペプチド |
| JPH06205692A (ja) | 1993-01-08 | 1994-07-26 | Asahi Chem Ind Co Ltd | 新規な抗ヒトトロンボモジュリンモノクロ−ナル抗体およびその抗体を用いたヒトトロンボモジュリンの高感度測定方法 |
| DE69434942T2 (de) | 1993-02-25 | 2007-11-29 | Abbott Laboratories, Abbott Park | Mehrzweckreagenzsystem zur schnellen lysierung von vollblutproben |
| JP3007785B2 (ja) | 1993-03-16 | 2000-02-07 | 旭化成工業株式会社 | トロンボモジュリン組成物およびその変性防止方法 |
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| US5916874A (en) | 1994-04-20 | 1999-06-29 | Asahi Kasei Kogyo Kabushiki Kaisha | Method for treating liver injury |
| JPH083065A (ja) | 1994-04-20 | 1996-01-09 | Asahi Chem Ind Co Ltd | 肝臓障害に対する治療剤 |
| JP2824392B2 (ja) | 1994-05-31 | 1998-11-11 | 旭化成工業株式会社 | トロンビンによるプロテインｃの活性化を促進する作用を有するペプチドを含有する培養上澄液 |
| US5827832A (en) | 1995-03-06 | 1998-10-27 | Interneuron Pharmaceuticals, Inc. | Method of protecting brain tissue from cerebral infarction subsequent to ischemia |
| US5872108A (en) | 1995-03-06 | 1999-02-16 | Interneuron Pharmaceuticals, Inc. | Reduction of infarct volume using citicoline |
| JPH11511732A (ja) | 1995-03-06 | 1999-10-12 | インターニューロン ファーマシューティカルズ，インコーポレーテッド | シチコリンを用いる梗塞容積の低減 |
| JP3789147B2 (ja) | 1995-04-11 | 2006-06-21 | 旭化成ファーマ株式会社 | 脊髄損傷後の神経障害に対する治療剤 |
| JPH08301783A (ja) | 1995-05-11 | 1996-11-19 | Mochida Pharmaceut Co Ltd | 吸収性骨疾患予防・治療剤 |
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| JP3931353B2 (ja) | 1995-06-30 | 2007-06-13 | 持田製薬株式会社 | 創傷治癒剤 |
| JP3745805B2 (ja) | 1995-10-24 | 2006-02-15 | 日本ケミカルリサーチ株式会社 | トロンボモジュリンの精製方法 |
| JPH101439A (ja) | 1996-06-11 | 1998-01-06 | Mochida Pharmaceut Co Ltd | 神経変性疾患治療剤 |
| JP4157644B2 (ja) | 1998-03-30 | 2008-10-01 | 旭化成ファーマ株式会社 | 高純度可溶性トロンボモジュリンの製造方法 |
| WO2001072328A2 (en) * | 2000-03-28 | 2001-10-04 | Eli Lilly And Company | Methods of treating diseases with activated protein c |
| US20020111296A1 (en) | 2000-08-31 | 2002-08-15 | Festoff Barry W. | Thrombomodulin analogs for use in recovery of spinal cord injury |
| JP4340540B2 (ja) * | 2002-01-18 | 2009-10-07 | 旭化成ファーマ株式会社 | 可溶性トロンボモジュリン高濃度含有製剤 |
| DK1664041T3 (da) * | 2003-09-22 | 2008-10-27 | Euro Celtique Sa | Phenylcarboxamidforbindelser, der er egnede til behandling af smerter |
| KR20070106027A (ko) * | 2005-02-16 | 2007-10-31 | 와이어쓰 | 백혈병의 진단, 예후 및 치료법의 선택을 위한 방법 및시스템 |
| US9394267B2 (en) | 2007-07-13 | 2016-07-19 | The Cleveland Clinic Foundation | Heterocyclic modulators of cannabinoid receptors |
| WO2009012221A1 (en) | 2007-07-13 | 2009-01-22 | Board Of Regents, The University Of Texas System | Heterocyclic modulators of cannabinoid receptors |
| HUE036546T2 (hu) * | 2008-02-18 | 2018-07-30 | Esteve Labor Dr | Szigma-receptor ligandumokhoz kötõdõ vegyületek alkalmazása kemoterápia következményeként kifejlõdõ neuropátiás fájdalom kezelésére |
| WO2010006634A1 (en) * | 2008-07-16 | 2010-01-21 | Paion Deutschland Gmbh | Prevention and treatment of radiation injury |
| TWI438009B (zh) * | 2010-02-19 | 2014-05-21 | Teikoku Pharma Usa Inc | 紫杉烷前－乳劑調配物及其製造與使用之方法 |
| JP2011178687A (ja) * | 2010-02-26 | 2011-09-15 | Kochi Univ | 造血細胞移植に伴う疼痛の予防および／または治療剤 |
| US20110287110A1 (en) * | 2010-04-23 | 2011-11-24 | Mark Wesley Dewhirst | Combination cancer treatment |
| JP5924611B2 (ja) | 2010-06-16 | 2016-05-25 | 国立大学法人高知大学 | 造血細胞移植に伴う生着症候群の予防及び／又は治療のための医薬 |
| WO2012015758A2 (en) * | 2010-07-30 | 2012-02-02 | Saint Louis University | Methods of treating pain |
| US10709767B2 (en) | 2012-05-31 | 2020-07-14 | Kinki University | Agent for prophylactic and/or therapeutic treatment of peripheral neuropathic pain caused by anticancer agent |
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2013
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- 2013-05-17 RU RU2014148171/15A patent/RU2595857C2/ru active
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- 2013-05-17 WO PCT/JP2013/063743 patent/WO2013179910A1/ja not_active Ceased
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- 2013-05-17 PT PT13796572T patent/PT2857037T/pt unknown
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- 2013-05-17 NZ NZ702242A patent/NZ702242A/en unknown
- 2013-05-17 CN CN201380028318.4A patent/CN104394885B/zh active Active
- 2013-05-17 JP JP2014518384A patent/JP6124417B2/ja active Active
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