JP6095366B2 - 疲労を治療又は予防するための方法 - Google Patents
疲労を治療又は予防するための方法 Download PDFInfo
- Publication number
- JP6095366B2 JP6095366B2 JP2012517622A JP2012517622A JP6095366B2 JP 6095366 B2 JP6095366 B2 JP 6095366B2 JP 2012517622 A JP2012517622 A JP 2012517622A JP 2012517622 A JP2012517622 A JP 2012517622A JP 6095366 B2 JP6095366 B2 JP 6095366B2
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- JP
- Japan
- Prior art keywords
- compound
- group
- sleep
- fatigue
- pharmaceutical composition
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
- A61K31/27—Esters, e.g. nitroglycerine, selenocyanates of carbamic or thiocarbamic acids, meprobamate, carbachol, neostigmine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/13—Amines
- A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
- A61K31/137—Arylalkylamines, e.g. amphetamine, epinephrine, salbutamol, ephedrine or methadone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/16—Amides, e.g. hydroxamic acids
- A61K31/17—Amides, e.g. hydroxamic acids having the group >N—C(O)—N< or >N—C(S)—N<, e.g. urea, thiourea, carmustine
- A61K31/175—Amides, e.g. hydroxamic acids having the group >N—C(O)—N< or >N—C(S)—N<, e.g. urea, thiourea, carmustine having the group, >N—C(O)—N=N— or, e.g. carbonohydrazides, carbazones, semicarbazides, semicarbazones; Thioanalogues thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/325—Carbamic acids; Thiocarbamic acids; Anhydrides or salts thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C271/00—Derivatives of carbamic acids, i.e. compounds containing any of the groups, the nitrogen atom not being part of nitro or nitroso groups
- C07C271/06—Esters of carbamic acids
- C07C271/08—Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms
- C07C271/10—Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms with the nitrogen atoms of the carbamate groups bound to hydrogen atoms or to acyclic carbon atoms
- C07C271/20—Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms with the nitrogen atoms of the carbamate groups bound to hydrogen atoms or to acyclic carbon atoms to carbon atoms of hydrocarbon radicals substituted by nitrogen atoms not being part of nitro or nitroso groups
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- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Organic Chemistry (AREA)
- Emergency Medicine (AREA)
- Engineering & Computer Science (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US21908209P | 2009-06-22 | 2009-06-22 | |
| US61/219,082 | 2009-06-22 | ||
| PCT/US2010/039313 WO2011005473A2 (en) | 2009-06-22 | 2010-06-21 | Methods for treating or preventing fatigue |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2015134556A Division JP6368285B2 (ja) | 2009-06-22 | 2015-07-03 | 疲労を治療又は予防するための方法 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2012530779A JP2012530779A (ja) | 2012-12-06 |
| JP2012530779A5 JP2012530779A5 (e) | 2015-01-15 |
| JP6095366B2 true JP6095366B2 (ja) | 2017-03-15 |
Family
ID=43429751
Family Applications (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2012517622A Active JP6095366B2 (ja) | 2009-06-22 | 2010-06-21 | 疲労を治療又は予防するための方法 |
| JP2015134556A Active JP6368285B2 (ja) | 2009-06-22 | 2015-07-03 | 疲労を治療又は予防するための方法 |
| JP2018128318A Pending JP2018188450A (ja) | 2009-06-22 | 2018-07-05 | 疲労を治療又は予防するための方法 |
Family Applications After (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2015134556A Active JP6368285B2 (ja) | 2009-06-22 | 2015-07-03 | 疲労を治療又は予防するための方法 |
| JP2018128318A Pending JP2018188450A (ja) | 2009-06-22 | 2018-07-05 | 疲労を治療又は予防するための方法 |
Country Status (12)
| Country | Link |
|---|---|
| US (5) | US8741950B2 (e) |
| EP (1) | EP2445490B1 (e) |
| JP (3) | JP6095366B2 (e) |
| KR (3) | KR20120098578A (e) |
| CN (2) | CN102481274A (e) |
| AU (1) | AU2010270971B2 (e) |
| BR (1) | BRPI1015233A2 (e) |
| IN (1) | IN2012DN00624A (e) |
| MX (1) | MX2012000034A (e) |
| RU (1) | RU2567801C2 (e) |
| TW (1) | TWI453014B (e) |
| WO (1) | WO2011005473A2 (e) |
Families Citing this family (24)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101217949B (zh) | 2005-06-08 | 2012-10-17 | 爱思开生物制药株式会社 | 治疗睡眠-清醒病症 |
| RU2567801C2 (ru) * | 2009-06-22 | 2015-11-10 | Ск Биофармасъютиклс Ко., Лтд. | Способы лечения и профилактики усталости |
| PL2496228T3 (pl) | 2009-11-06 | 2014-06-30 | Sk Biopharmaceuticals Co Ltd | Sposoby leczenia zespołu nadpobudliwości psychoruchowej/deficytu uwagi |
| AU2010316172B2 (en) | 2009-11-06 | 2015-11-12 | Sk Biopharmaceuticals Co., Ltd. | Methods for treating fibromyalgia syndrome |
| US8623913B2 (en) | 2010-06-30 | 2014-01-07 | Sk Biopharmaceuticals Co., Ltd. | Methods for treating restless legs syndrome |
| US9610274B2 (en) | 2010-06-30 | 2017-04-04 | Sk Biopharmaceuticals Co., Ltd. | Methods for treating bipolar disorder |
| CA2853779C (en) | 2011-12-21 | 2016-04-26 | Innobioscience, Llc | Combined therapy with interferon and andrographolides for multiple sclerosis |
| HRP20221018T1 (hr) | 2013-03-13 | 2023-01-06 | Jazz Pharmaceuticals Ireland Limited | Liječenje katapleksije |
| KR20210152011A (ko) * | 2013-07-12 | 2021-12-14 | 에스케이바이오팜 주식회사 | 금연의 촉진 |
| PL3021838T3 (pl) | 2013-07-18 | 2021-03-08 | Jazz Pharmaceuticals Ireland Limited | Leczenie otyłości |
| DK3065751T3 (da) * | 2013-11-08 | 2020-03-09 | Legacy Healthcare Ltd | Metode til behandling af kræft og kræftkomorbiditet |
| US10888542B2 (en) | 2014-02-28 | 2021-01-12 | Sk Biopharmaceuticals Co., Ltd. | Aminocarbonylcarbamate compounds |
| TWI698415B (zh) | 2014-02-28 | 2020-07-11 | 南韓商愛思開生物製藥股份有限公司 | 胺基羰基胺基甲酸酯化合物 |
| US10195151B2 (en) | 2016-09-06 | 2019-02-05 | Jazz Pharmaceuticals International Iii Limited | Formulations of (R)-2-amino-3-phenylpropyl carbamate |
| JP7219213B2 (ja) | 2016-09-06 | 2023-02-07 | ジャズ ファーマスティカルズ アイルランド リミテッド | (r)-2-アミノ-3-フェニルプロピルカルバメートの溶媒和物フォーム |
| EP4316592A3 (en) * | 2016-10-06 | 2024-05-01 | Axsome Malta Ltd. | Carbamoyl phenylalaninol compounds and uses thereof |
| JP2020514465A (ja) * | 2016-12-30 | 2020-05-21 | ドンジン セミケム カンパニー リミテッドDongjin Semichem Co., Ltd. | コーティング組成物およびこれから製造されるフィルム |
| US10959976B2 (en) | 2017-06-02 | 2021-03-30 | Jazz Pharmaceuticals Ireland Limited | Methods and compositions for treating excessive sleepiness |
| EP3661911A4 (en) | 2017-07-31 | 2021-04-14 | Jazz Pharmaceuticals Ireland Limited | CARBAMOYL-PHENYLALANINOL ANALOGS AND USES THEREOF |
| JP7428480B2 (ja) * | 2019-06-06 | 2024-02-06 | 雪印メグミルク株式会社 | 睡眠改善用組成物及び組成物を含む食品、医薬品、飼料 |
| US10940133B1 (en) | 2020-03-19 | 2021-03-09 | Jazz Pharmaceuticals Ireland Limited | Methods of providing solriamfetol therapy to subjects with impaired renal function |
| KR102390194B1 (ko) | 2020-08-03 | 2022-04-25 | 셀라이온바이오메드 주식회사 | 페닐알킬 카바메이트 화합물을 포함하는 Kca3.1채널 매개질환 치료용 조성물 |
| WO2023091921A1 (en) * | 2021-11-16 | 2023-05-25 | Axsome Malta Ltd. | Methods and compositions for treating cognitive impairment |
| WO2025006965A1 (en) | 2023-06-29 | 2025-01-02 | Axsome Therapeutics, Inc. | Methods of administering solriamfetol to lactating women |
Family Cites Families (24)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| NZ260667A (en) | 1993-06-10 | 1997-05-26 | Lilly Co Eli | Preventing emesis or treating sexual dysfunction using tetrahydrobenz[cd]indole 6-carboxamides |
| KR100197892B1 (ko) * | 1994-09-09 | 1999-06-15 | 남창우 | 신규한 페닐알킬아미노 카바메이트 화합물과 그의 제조방법 |
| KR0173862B1 (ko) | 1995-02-11 | 1999-04-01 | 조규향 | O-카바모일-(d)-페닐알라닌올 화합물과 그의 약제학적으로 유용한 염 및 이들의 제조방법 |
| US5756817C1 (en) | 1995-02-11 | 2001-04-17 | Sk Corp | O-carbamoyl-phenylananinol compounds their pharmaceutically useful salts and process for preparing the same |
| KR0173863B1 (ko) | 1995-04-10 | 1999-04-01 | 조규향 | 페닐에 치환체가 있는 o-카바모일-페닐알라닌올 화합물과 그의 약제학적으로 유용한 염 및 이들의 제조방법 |
| AU4567597A (en) | 1996-10-08 | 1998-05-05 | Institute Of Child Health | Mutant ciita molecule and uses thereof |
| JP4068154B2 (ja) * | 1996-10-10 | 2008-03-26 | エス ケー コーポレイション | O―カルバモイル―フェニルアラニノール化合物とその薬剤学的に有用な塩及びその製造方法 |
| WO1998017636A1 (en) | 1996-10-22 | 1998-04-30 | Ortho Pharmaceutical Corporation | Phenylalaninol derivatives for the treatment of central nervous system disorders |
| US20040229951A1 (en) | 2003-05-15 | 2004-11-18 | Arthur Vanmoor | Method of treating fatigue by enhancing the effectiveness of the human immune system |
| RU2267319C2 (ru) * | 2003-07-15 | 2006-01-10 | Общество с ограниченной ответственностью "Интер-Кэр" | Фармацевтическая композиция и способ лечения синдрома хронической усталости с ее использованием |
| US20050080268A1 (en) | 2003-10-08 | 2005-04-14 | Yong-Moon Choi | Process of preparing O-carbamoyl compounds in the presence of active amine group |
| BRPI0518233A2 (pt) | 2004-10-28 | 2008-11-11 | Sk Corp | terapia adjunta para depressço |
| CN101217949B (zh) * | 2005-06-08 | 2012-10-17 | 爱思开生物制药株式会社 | 治疗睡眠-清醒病症 |
| ATE459393T1 (de) | 2005-06-22 | 2010-03-15 | Sk Holdings Co Ltd | Behandlung der sexuellen dysfunktion |
| CN101272776B (zh) | 2005-07-26 | 2012-10-03 | 詹森药业有限公司 | 氨基甲酸酯在制备治疗物质滥用相关疾病药物中的用途 |
| JP2010506845A (ja) | 2006-10-13 | 2010-03-04 | ジヤンセン・フアーマシユーチカ・ナームローゼ・フエンノートシヤツプ | フェニルアルキルアミノカルバメート組成物 |
| RU2567801C2 (ru) | 2009-06-22 | 2015-11-10 | Ск Биофармасъютиклс Ко., Лтд. | Способы лечения и профилактики усталости |
| US8232315B2 (en) | 2009-06-26 | 2012-07-31 | Sk Biopharmaceuticals Co., Ltd. | Methods for treating drug addiction and improving addiction-related behavior |
| PL2496228T3 (pl) | 2009-11-06 | 2014-06-30 | Sk Biopharmaceuticals Co Ltd | Sposoby leczenia zespołu nadpobudliwości psychoruchowej/deficytu uwagi |
| AU2010316172B2 (en) | 2009-11-06 | 2015-11-12 | Sk Biopharmaceuticals Co., Ltd. | Methods for treating fibromyalgia syndrome |
| US9610274B2 (en) | 2010-06-30 | 2017-04-04 | Sk Biopharmaceuticals Co., Ltd. | Methods for treating bipolar disorder |
| US8623913B2 (en) | 2010-06-30 | 2014-01-07 | Sk Biopharmaceuticals Co., Ltd. | Methods for treating restless legs syndrome |
| HRP20221018T1 (hr) * | 2013-03-13 | 2023-01-06 | Jazz Pharmaceuticals Ireland Limited | Liječenje katapleksije |
| JP6215740B2 (ja) * | 2014-03-14 | 2017-10-18 | 本田技研工業株式会社 | 部品の締結構造 |
-
2010
- 2010-06-21 RU RU2012101947/15A patent/RU2567801C2/ru active
- 2010-06-21 EP EP10797541.9A patent/EP2445490B1/en active Active
- 2010-06-21 BR BRPI1015233A patent/BRPI1015233A2/pt not_active Application Discontinuation
- 2010-06-21 WO PCT/US2010/039313 patent/WO2011005473A2/en not_active Ceased
- 2010-06-21 KR KR1020127001795A patent/KR20120098578A/ko not_active Ceased
- 2010-06-21 US US13/379,793 patent/US8741950B2/en active Active
- 2010-06-21 KR KR1020197026173A patent/KR102173587B1/ko active Active
- 2010-06-21 CN CN2010800277527A patent/CN102481274A/zh active Pending
- 2010-06-21 CN CN201710080968.3A patent/CN106727486A/zh active Pending
- 2010-06-21 IN IN624DEN2012 patent/IN2012DN00624A/en unknown
- 2010-06-21 KR KR1020177020249A patent/KR102021075B1/ko active Active
- 2010-06-21 JP JP2012517622A patent/JP6095366B2/ja active Active
- 2010-06-21 AU AU2010270971A patent/AU2010270971B2/en active Active
- 2010-06-21 MX MX2012000034A patent/MX2012000034A/es active IP Right Grant
- 2010-06-22 TW TW099120382A patent/TWI453014B/zh active
-
2014
- 2014-05-07 US US14/271,503 patent/US9464041B2/en active Active
-
2015
- 2015-07-03 JP JP2015134556A patent/JP6368285B2/ja active Active
-
2016
- 2016-09-16 US US15/268,060 patent/US9999609B2/en active Active
-
2018
- 2018-05-18 US US15/983,944 patent/US10507192B2/en active Active
- 2018-07-05 JP JP2018128318A patent/JP2018188450A/ja active Pending
-
2019
- 2019-10-31 US US16/670,382 patent/US20200061017A1/en not_active Abandoned
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