BRPI0518233A2 - terapia adjunta para depressço - Google Patents

terapia adjunta para depressço

Info

Publication number
BRPI0518233A2
BRPI0518233A2 BRPI0518233-6A BRPI0518233A BRPI0518233A2 BR PI0518233 A2 BRPI0518233 A2 BR PI0518233A2 BR PI0518233 A BRPI0518233 A BR PI0518233A BR PI0518233 A2 BRPI0518233 A2 BR PI0518233A2
Authority
BR
Brazil
Prior art keywords
carbon atoms
hydrogen
group
depression
atoms
Prior art date
Application number
BRPI0518233-6A
Other languages
English (en)
Inventor
Jonathan Sporn
Original Assignee
Sk Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sk Corp filed Critical Sk Corp
Publication of BRPI0518233A2 publication Critical patent/BRPI0518233A2/pt

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/27—Esters, e.g. nitroglycerine, selenocyanates of carbamic or thiocarbamic acids, meprobamate, carbachol, neostigmine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00—Medicinal preparations containing inorganic active ingredients
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Abstract

TERAPIA ADJUNTA PARA DEPRESSçO. A presente invenção refere-se a um método de tratamento de depressão em um indivíduo compreendendo a etapa da administração de uma quantidade terapeuticamente eficaz de um antidepressivo convencional e, em adição, administração ao indivíduo de uma quantidade terapeutica- mente eficaz de um composto da Fórmula (1) ou um sal ou éster farmaceuticamente aceitável do mesmo onde Rx é um membro selecionado do grupo consistindo em hidrogênio, alquila inferior de 1 a 8 átomos de carbono, halogênio selecionado de F, Cl, Br e 1, alcóxi contendo 1 a 3 átomos de carbono, nitro, hidróxi, trifluormetila e tioalcóxi contendo 1 a 3 átomos de carbono; x é um inteiro de 1 a 3, contanto que R possa ser igual ou diferente quando x for 2 ou 3; R1 e R2 podem ser iguais ou diferentes um do outro e são independentemente selecionados do grupo consistindo em hidrogênio, alquila inferior de 1 a 8 átomos de carbono, ana, arilalquila, cicloalquila de 3 a 7 átomos de carbono; R1 e R2 podem ser unidos para formarem um heterociclo de 5 a 7 membros substituído com um membro selecionado do grupo consistindo em grupos hidrogênio, alquila e arila, onde o composto cíclico pode compreender 1 a 2 átomos de nitrogênio e O a 1 átomo de oxigênio, onde os átomos de nitrogênio não estão diretamente conectados uns aos outros ou com o átomo de oxigênio.
BRPI0518233-6A 2004-10-28 2005-10-26 terapia adjunta para depressço BRPI0518233A2 (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US62304404P 2004-10-28 2004-10-28
PCT/US2005/038804 WO2006050037A1 (en) 2004-10-28 2005-10-26 Adjunctive therapy for depression

Publications (1)

Publication Number Publication Date
BRPI0518233A2 true BRPI0518233A2 (pt) 2008-11-11

Family

ID=35966035

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI0518233-6A BRPI0518233A2 (pt) 2004-10-28 2005-10-26 terapia adjunta para depressço

Country Status (12)

Country Link
US (1) US8729120B2 (pt)
EP (1) EP1819328A1 (pt)
JP (1) JP2008518921A (pt)
KR (1) KR20070083826A (pt)
CN (1) CN101132787A (pt)
AU (1) AU2005302589B2 (pt)
BR (1) BRPI0518233A2 (pt)
CA (1) CA2587481A1 (pt)
IL (1) IL182746A (pt)
MX (1) MX2007005172A (pt)
RU (1) RU2007119648A (pt)
WO (1) WO2006050037A1 (pt)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
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CN101217949B (zh) 2005-06-08 2012-10-17 爱思开生物制药株式会社 治疗睡眠-清醒病症
ATE459393T1 (de) * 2005-06-22 2010-03-15 Sk Holdings Co Ltd Behandlung der sexuellen dysfunktion
MX2009004770A (es) * 2006-10-30 2009-08-17 Janssen Pharmaceutica Nv Compuestos de carbamato para usarse en el tratamiento de la depresion.
KR20120098578A (ko) * 2009-06-22 2012-09-05 에스케이바이오팜 주식회사 피로의 치료 또는 예방 방법
AU2010316106B2 (en) 2009-11-06 2015-10-22 Sk Biopharmaceuticals Co., Ltd. Methods for treating attention-deficit/hyperactivity disorder
US8927602B2 (en) * 2009-11-06 2015-01-06 Sk Biopharmaceuticals Co., Ltd. Methods for treating fibromyalgia syndrome
US8623913B2 (en) 2010-06-30 2014-01-07 Sk Biopharmaceuticals Co., Ltd. Methods for treating restless legs syndrome
US9610274B2 (en) 2010-06-30 2017-04-04 Sk Biopharmaceuticals Co., Ltd. Methods for treating bipolar disorder
SI2968208T1 (sl) 2013-03-13 2023-02-28 Jazz Pharmaceuticals Ireland Limited, Zdravljenje katapleksije
KR20160030955A (ko) * 2013-07-12 2016-03-21 에스케이바이오팜 주식회사 금연의 촉진
EP3021838B1 (en) 2013-07-18 2020-05-27 Jazz Pharmaceuticals Ireland Limited Treatment for obesity
TWI655179B (zh) 2014-02-28 2019-04-01 南韓商愛思開生物製藥股份有限公司 胺基羰基胺基甲酸酯化合物
US10888542B2 (en) 2014-02-28 2021-01-12 Sk Biopharmaceuticals Co., Ltd. Aminocarbonylcarbamate compounds
JP6466792B2 (ja) * 2015-07-03 2019-02-06 エスケー バイオファーマスティカルズ カンパニー リミテッド 注意欠陥／多動性障害（ａｄｈｄ）の治療方法
US10195151B2 (en) 2016-09-06 2019-02-05 Jazz Pharmaceuticals International Iii Limited Formulations of (R)-2-amino-3-phenylpropyl carbamate
MY197630A (en) 2016-09-06 2023-06-29 Sk Biopharmaceuticals Co Ltd Solvate form of (r)-2-amino-3-phenylpropyl carbamate
EP4316592A2 (en) * 2016-10-06 2024-02-07 Axsome Malta Ltd. Carbamoyl phenylalaninol compounds and uses thereof
BR112019025286A2 (pt) 2017-06-02 2020-06-23 Jazz Pharmaceuticals Ireland Limited Métodos e composições para tratamento de sonolência excessiva
CA3071779A1 (en) 2017-07-31 2019-02-07 Jazz Pharmaceuticals Ireland Limited Carbamoyl phenylalaninol analogs and uses thereof
CN110655500B (zh) * 2018-06-28 2020-12-08 浙江京新药业股份有限公司 氨基甲酸酯衍生物及其制备方法和用途
US10940133B1 (en) 2020-03-19 2021-03-09 Jazz Pharmaceuticals Ireland Limited Methods of providing solriamfetol therapy to subjects with impaired renal function

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR100197892B1 (ko) 1994-09-09 1999-06-15 남창우 신규한 페닐알킬아미노 카바메이트 화합물과 그의 제조방법
KR0173862B1 (ko) 1995-02-11 1999-04-01 조규향 O-카바모일-(d)-페닐알라닌올 화합물과 그의 약제학적으로 유용한 염 및 이들의 제조방법
US5756817C1 (en) * 1995-02-11 2001-04-17 Sk Corp O-carbamoyl-phenylananinol compounds their pharmaceutically useful salts and process for preparing the same
KR0173863B1 (ko) 1995-04-10 1999-04-01 조규향 페닐에 치환체가 있는 o-카바모일-페닐알라닌올 화합물과 그의 약제학적으로 유용한 염 및 이들의 제조방법
US6627653B2 (en) * 2000-08-02 2003-09-30 Ortho-Mcneil Pharmaceutical, Inc. Anticonvulsant derivatives useful for the treatment of depression
AR042806A1 (es) * 2002-12-27 2005-07-06 Otsuka Pharma Co Ltd Combinacion de derivados de carboestirilo e inhibidores de la reabsorcion de serotonina para el tratamiento de trastornos del animo
DK1575590T3 (da) 2002-12-27 2008-02-11 Otsuka Pharma Co Ltd Carbostyrilderivater og serotoningenoptagelsesinhibitorer til behandling af sindsstemningslidelser

Also Published As

Publication number Publication date
AU2005302589A1 (en) 2006-05-11
MX2007005172A (es) 2007-06-22
US8729120B2 (en) 2014-05-20
IL182746A0 (en) 2007-09-20
AU2005302589B2 (en) 2010-09-16
RU2007119648A (ru) 2008-12-10
US20080039529A1 (en) 2008-02-14
JP2008518921A (ja) 2008-06-05
CN101132787A (zh) 2008-02-27
CA2587481A1 (en) 2006-05-11
WO2006050037A1 (en) 2006-05-11
KR20070083826A (ko) 2007-08-24
IL182746A (en) 2014-08-31
EP1819328A1 (en) 2007-08-22

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Legal Events

Date Code Title Description
B25D Requested change of name of applicant approved

Owner name: SK HOLDINGS CO., LTD. (KR)

Free format text: ALTERADO DE: SK CORPORATION

B06T Formal requirements before examination [chapter 6.20 patent gazette]
B06F Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette]
B07D Technical examination (opinion) related to article 229 of industrial property law [chapter 7.4 patent gazette]

Free format text: DE ACORDO COM O ARTIGO 229-C DA LEI NO 10196/2001, QUE MODIFICOU A LEI NO 9279/96, A CONCESSAO DA PATENTE ESTA CONDICIONADA A ANUENCIA PREVIA DA ANVISA. CONSIDERANDO A APROVACAO DOS TERMOS DO PARECER NO 337/PGF/EA/2010, BEM COMO A PORTARIA INTERMINISTERIAL NO 1065 DE 24/05/2012, ENCAMINHA-SE O PRESENTE PEDIDO PARA AS PROVIDENCIAS CABIVEIS.

B07E Notification of approval relating to section 229 industrial property law [chapter 7.5 patent gazette]
B07A Application suspended after technical examination (opinion) [chapter 7.1 patent gazette]
B09B Patent application refused [chapter 9.2 patent gazette]
B25A Requested transfer of rights approved

Owner name: SK BIOPHARMACEUTICALS CO., LTD. (KR)

B09B Patent application refused [chapter 9.2 patent gazette]

Free format text: MANTIDO O INDEFERIMENTO UMA VEZ QUE NAO FOI APRESENTADO RECURSO DENTRO DO PRAZO LEGAL