JP6049712B2 - 抗癌治療及び画像化並びに骨障害治療のための金属ビスホスホネートナノ粒子 - Google Patents

抗癌治療及び画像化並びに骨障害治療のための金属ビスホスホネートナノ粒子 Download PDF

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JP6049712B2
JP6049712B2 JP2014520238A JP2014520238A JP6049712B2 JP 6049712 B2 JP6049712 B2 JP 6049712B2 JP 2014520238 A JP2014520238 A JP 2014520238A JP 2014520238 A JP2014520238 A JP 2014520238A JP 6049712 B2 JP6049712 B2 JP 6049712B2
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nanoparticles
group
bisphosphonate
metal
zol
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JP2014520849A5 (enExample
JP2014520849A (ja
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リン ウェンビン
リン ウェンビン
リォウ デミン
リォウ デミン
デラロッカ ジョセフ
デラロッカ ジョセフ
エー クレーマー ステファニー
エー クレーマー ステファニー
ワイ プーン クリストファー
ワイ プーン クリストファー
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University of North Carolina at Chapel Hill
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    • A61K9/127—Synthetic bilayered vehicles, e.g. liposomes or liposomes with cholesterol as the only non-phosphatidyl surfactant
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    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/66—Phosphorus compounds
    • A61K31/662—Phosphorus acids or esters thereof having P—C bonds, e.g. foscarnet, trichlorfon
    • A61K31/663—Compounds having two or more phosphorus acid groups or esters thereof, e.g. clodronic acid, pamidronic acid
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JP2014520238A 2011-07-08 2012-07-09 抗癌治療及び画像化並びに骨障害治療のための金属ビスホスホネートナノ粒子 Active JP6049712B2 (ja)

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US201161505806P 2011-07-08 2011-07-08
US61/505,806 2011-07-08
PCT/US2012/045954 WO2013009701A2 (en) 2011-07-08 2012-07-09 Metal bisphosphonate nanoparticles for anti-cancer therapy and imaging and for treating bone disorders

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JP2014520849A JP2014520849A (ja) 2014-08-25
JP2014520849A5 JP2014520849A5 (enExample) 2015-08-27
JP6049712B2 true JP6049712B2 (ja) 2016-12-21

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US (3) US9693957B2 (enExample)
EP (2) EP3494974B1 (enExample)
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