JP6013303B2 - ピペット装置および検査液のピペット操作方法 - Google Patents

ピペット装置および検査液のピペット操作方法 Download PDF

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JP6013303B2
JP6013303B2 JP2013210414A JP2013210414A JP6013303B2 JP 6013303 B2 JP6013303 B2 JP 6013303B2 JP 2013210414 A JP2013210414 A JP 2013210414A JP 2013210414 A JP2013210414 A JP 2013210414A JP 6013303 B2 JP6013303 B2 JP 6013303B2
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liquid
test
nozzle
amount
pipetting
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JP2014081371A5 (enExample
JP2014081371A (ja
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フッター ローランド
フッター ローランド
ストエクリ ローランド
ストエクリ ローランド
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エフ ホフマン−ラ ロッシュ アクチェン ゲゼルシャフト
エフ ホフマン−ラ ロッシュ アクチェン ゲゼルシャフト
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    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/02—Burettes; Pipettes
    • B01L3/021—Pipettes, i.e. with only one conduit for withdrawing and redistributing liquids
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L13/00—Cleaning or rinsing apparatus
    • B01L13/02—Cleaning or rinsing apparatus for receptacle or instruments
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N35/10—Devices for transferring samples or any liquids to, in, or from, the analysis apparatus, e.g. suction devices, injection devices
    • G01N35/1004—Cleaning sample transfer devices
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N35/10—Devices for transferring samples or any liquids to, in, or from, the analysis apparatus, e.g. suction devices, injection devices
    • G01N35/1009—Characterised by arrangements for controlling the aspiration or dispense of liquids
    • G01N35/1016—Control of the volume dispensed or introduced
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2200/00—Solutions for specific problems relating to chemical or physical laboratory apparatus
    • B01L2200/06—Fluid handling related problems
    • B01L2200/0615—Loss of fluid by dripping
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2200/00—Solutions for specific problems relating to chemical or physical laboratory apparatus
    • B01L2200/06—Fluid handling related problems
    • B01L2200/0684—Venting, avoiding backpressure, avoid gas bubbles
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2200/00—Solutions for specific problems relating to chemical or physical laboratory apparatus
    • B01L2200/14—Process control and prevention of errors
    • B01L2200/141—Preventing contamination, tampering
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2200/00—Solutions for specific problems relating to chemical or physical laboratory apparatus
    • B01L2200/14—Process control and prevention of errors
    • B01L2200/143—Quality control, feedback systems
    • B01L2200/146—Employing pressure sensors
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2400/00—Moving or stopping fluids
    • B01L2400/04—Moving fluids with specific forces or mechanical means
    • B01L2400/0475—Moving fluids with specific forces or mechanical means specific mechanical means and fluid pressure
    • B01L2400/0487—Moving fluids with specific forces or mechanical means specific mechanical means and fluid pressure fluid pressure, pneumatics
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N35/10—Devices for transferring samples or any liquids to, in, or from, the analysis apparatus, e.g. suction devices, injection devices
    • G01N35/1009—Characterised by arrangements for controlling the aspiration or dispense of liquids
    • G01N35/1016—Control of the volume dispensed or introduced
    • G01N2035/1018—Detecting inhomogeneities, e.g. foam, bubbles, clots
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T436/00—Chemistry: analytical and immunological testing
    • Y10T436/25—Chemistry: analytical and immunological testing including sample preparation
    • Y10T436/2575—Volumetric liquid transfer

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  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Physics & Mathematics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Clinical Laboratory Science (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Immunology (AREA)
  • Pathology (AREA)
  • Automatic Analysis And Handling Materials Therefor (AREA)
  • Sampling And Sample Adjustment (AREA)
JP2013210414A 2012-10-12 2013-10-07 ピペット装置および検査液のピペット操作方法 Active JP6013303B2 (ja)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP12188267.4 2012-10-12
EP12188267.4A EP2719461B8 (en) 2012-10-12 2012-10-12 Method of pipetting a test liquid

Publications (3)

Publication Number Publication Date
JP2014081371A JP2014081371A (ja) 2014-05-08
JP2014081371A5 JP2014081371A5 (enExample) 2015-12-10
JP6013303B2 true JP6013303B2 (ja) 2016-10-25

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JP2013210414A Active JP6013303B2 (ja) 2012-10-12 2013-10-07 ピペット装置および検査液のピペット操作方法

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Country Link
US (1) US9878322B2 (enExample)
EP (1) EP2719461B8 (enExample)
JP (1) JP6013303B2 (enExample)
CN (1) CN103728461B (enExample)

Families Citing this family (37)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN103008037B (zh) * 2012-12-31 2015-04-01 浙江大学 一种具有皮升级精度的自动化微液滴阵列筛选系统的使用方法
JP6230450B2 (ja) * 2014-03-10 2017-11-15 株式会社日立ハイテクノロジーズ 分注装置及び分注方法
JP2015175837A (ja) * 2014-03-18 2015-10-05 ソニー株式会社 ピペットチップ用板状部材、ピペットチップ、液体撹拌用キット及び液体撹拌装置
CN104049045A (zh) * 2014-05-21 2014-09-17 江苏德峰药业有限公司 一种高粘度或高凝固点物质的气相针维护方法
CN105334332B (zh) * 2014-07-01 2018-10-16 深圳迈瑞生物医疗电子股份有限公司 样本分析仪及其样本采集和分配方法
CN107533079B (zh) * 2015-04-24 2021-06-29 株式会社日立高新技术 自动分析装置及方法
EP3314269A4 (en) 2015-06-26 2019-01-23 Abbott Laboratories REACTION TANK EXCHANGER DEVICE FOR DIAGNOSTIC ANALYZER
ES2560110B1 (es) * 2015-06-26 2016-09-09 Grifols, S.A. Aparato para la realización automática de análisis de inmunohematología en tarjetas de gel
JP6676300B2 (ja) * 2015-07-28 2020-04-08 ヤマハ発動機株式会社 対象物移動方法及び装置
DE102015011970B4 (de) * 2015-09-09 2017-04-06 Scienion Ag Dispensiergerät und entsprechendes Dispensierverfahren
JP6823364B2 (ja) * 2015-09-15 2021-02-03 サッポロビール株式会社 樽洗浄方法及び樽洗浄装置
JP6648764B2 (ja) * 2015-11-13 2020-02-14 コニカミノルタ株式会社 反応方法
CN105413773B (zh) * 2015-12-22 2017-12-12 江苏四新界面剂科技有限公司 具有自动判别液体储罐内压功能的取液器
WO2017223214A1 (en) 2016-06-22 2017-12-28 Abbott Laboratories Liquid level sensing apparatus and related methods
US10503177B2 (en) * 2016-08-03 2019-12-10 Safe Harbor Associates LLC Additive delivery system with sensors
JP2018096915A (ja) * 2016-12-15 2018-06-21 株式会社堀場製作所 自動分析装置
US11231432B2 (en) * 2017-03-08 2022-01-25 Hitachi High-Tech Corporation Automatic analysis device and automatic analysis method
EP3381560A1 (de) * 2017-03-28 2018-10-03 Eppendorf AG Verfahren und dosiervorrichtung zum kontaktdosieren von flüssigkeiten
LU100170B1 (de) * 2017-04-13 2018-10-15 Cytena Gmbh Verfahren zum Prozessieren einer flüssigen Probe
US20200264207A1 (en) * 2017-08-25 2020-08-20 Beckman Coulter, Inc. Substance dispense system for biological sample analysis instrument
WO2019060716A1 (en) * 2017-09-25 2019-03-28 Freenome Holdings, Inc. SAMPLE EXTRACTION METHODS AND SYSTEMS
EP3477307B1 (en) * 2017-10-24 2020-07-22 F. Hoffmann-La Roche AG Pipetting device and pipetting device positioning system
EP3502656B1 (en) * 2017-12-22 2022-09-21 Tecan Trading Ag A pipetting apparatus, a liquid handling system and a method of controlling pipetting
US11590491B2 (en) * 2017-12-28 2023-02-28 Formulatrix, Inc. Automatic liquid transfer optimization pipetting apparatus and method
JP7456719B2 (ja) * 2017-12-28 2024-03-27 シスメックス株式会社 検体測定装置および検体測定方法
JP7376905B2 (ja) * 2019-07-02 2023-11-09 株式会社ピーエムティー 希釈装置
CN110404597B (zh) * 2019-08-08 2024-08-16 天津药明康德新药开发有限公司 一种多功能自清洁移液装置及其使用方法
EP3832315B1 (en) * 2019-12-06 2025-05-28 F. Hoffmann-La Roche AG Pipetting unit and pipetting method for closed liquid containers
JP7417463B2 (ja) * 2020-04-24 2024-01-18 株式会社日立ハイテク 分注装置、自動分析装置、分注方法
EP4193131A4 (en) * 2020-08-10 2024-10-16 Agilent Technologies, Inc. PRESSURE BASED LIQUID LEVEL DETECTION
US20220268796A1 (en) * 2021-02-19 2022-08-25 Roche Molecular Systems, Inc. Method of Operating a Laboratory Instrument
GB2607892A (en) * 2021-06-11 2022-12-21 Spt Labtech Ltd Liquid aspirating or dispensing method and apparatus
US12226776B2 (en) 2021-11-04 2025-02-18 Instrumentation Laboratory Company Preparing substances in a medical diagnostic system
JPWO2023100791A1 (enExample) * 2021-12-03 2023-06-08
WO2023159085A1 (en) * 2022-02-15 2023-08-24 Gate Scientific, Inc. Sample testing devices and methods
CN115407077B (zh) * 2022-05-19 2025-05-13 中元汇吉生物技术股份有限公司 样本加注设备、方法及分析仪
CN115747050A (zh) * 2022-11-18 2023-03-07 上海英医达医疗器械用品有限公司 减少气泡与残液的移液方法

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS54155088A (en) * 1978-05-29 1979-12-06 Hitachi Ltd Liquid sample partial injection method and its device
JPS57208461A (en) * 1981-06-18 1982-12-21 Shimadzu Corp Distributing method for liquid sample
JPS62228954A (ja) * 1986-03-31 1987-10-07 Toshiba Corp 自動化学分析装置の分注方法
US5918291A (en) * 1995-06-07 1999-06-29 Inacu; Fulga Method for liquid aspiration from a sealed container
US6370942B1 (en) * 2000-05-15 2002-04-16 Dade Behring Inc. Method for verifying the integrity of a fluid transfer
JP4783170B2 (ja) * 2006-02-13 2011-09-28 株式会社東芝 自動分析装置
EP1947463A1 (en) * 2007-01-16 2008-07-23 Roche Diagnostics GmbH Collection of liquid analytical samples for clinical analytical purpose
JP2008281480A (ja) * 2007-05-11 2008-11-20 Olympus Corp ノズル洗浄方法およびノズル洗浄装置ならびに自動分析装置
JP2010133924A (ja) * 2008-10-28 2010-06-17 Sysmex Corp 液体吸引機構および試料分析装置

Also Published As

Publication number Publication date
US9878322B2 (en) 2018-01-30
EP2719461B8 (en) 2023-08-16
US20140106467A1 (en) 2014-04-17
EP2719461B1 (en) 2023-07-12
EP2719461C0 (en) 2023-07-12
CN103728461B (zh) 2017-10-24
JP2014081371A (ja) 2014-05-08
CN103728461A (zh) 2014-04-16
EP2719461A1 (en) 2014-04-16

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