JP5910412B2 - 微小粒子分取方法及び微小粒子分取用マイクロチップ - Google Patents

微小粒子分取方法及び微小粒子分取用マイクロチップ Download PDF

Info

Publication number
JP5910412B2
JP5910412B2 JP2012180317A JP2012180317A JP5910412B2 JP 5910412 B2 JP5910412 B2 JP 5910412B2 JP 2012180317 A JP2012180317 A JP 2012180317A JP 2012180317 A JP2012180317 A JP 2012180317A JP 5910412 B2 JP5910412 B2 JP 5910412B2
Authority
JP
Japan
Prior art keywords
flow path
sorting
channel
sheath
sheath liquid
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
JP2012180317A
Other languages
English (en)
Japanese (ja)
Other versions
JP2014036604A (ja
JP2014036604A5 (enExample
Inventor
達巳 伊藤
達巳 伊藤
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sony Corp
Original Assignee
Sony Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sony Corp filed Critical Sony Corp
Priority to JP2012180317A priority Critical patent/JP5910412B2/ja
Priority to US13/963,188 priority patent/US9737912B2/en
Priority to CN201310347353.4A priority patent/CN103586221B/zh
Priority to CN201611205723.0A priority patent/CN107051911B/zh
Publication of JP2014036604A publication Critical patent/JP2014036604A/ja
Publication of JP2014036604A5 publication Critical patent/JP2014036604A5/ja
Application granted granted Critical
Publication of JP5910412B2 publication Critical patent/JP5910412B2/ja
Priority to US15/658,693 priority patent/US10562074B2/en
Priority to US16/733,601 priority patent/US11148173B2/en
Priority to US17/469,335 priority patent/US11666946B2/en
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Images

Classifications

    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B07—SEPARATING SOLIDS FROM SOLIDS; SORTING
    • B07C—POSTAL SORTING; SORTING INDIVIDUAL ARTICLES, OR BULK MATERIAL FIT TO BE SORTED PIECE-MEAL, e.g. BY PICKING
    • B07C5/00—Sorting according to a characteristic or feature of the articles or material being sorted, e.g. by control effected by devices which detect or measure such characteristic or feature; Sorting by manually actuated devices, e.g. switches
    • B07C5/34—Sorting according to other particular properties
    • B07C5/342—Sorting according to other particular properties according to optical properties, e.g. colour
    • B07C5/3425—Sorting according to other particular properties according to optical properties, e.g. colour of granular material, e.g. ore particles, grain
    • B07C5/3427—Sorting according to other particular properties according to optical properties, e.g. colour of granular material, e.g. ore particles, grain by changing or intensifying the optical properties prior to scanning, e.g. by inducing fluorescence under UV or x-radiation, subjecting the material to a chemical reaction
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B07—SEPARATING SOLIDS FROM SOLIDS; SORTING
    • B07C—POSTAL SORTING; SORTING INDIVIDUAL ARTICLES, OR BULK MATERIAL FIT TO BE SORTED PIECE-MEAL, e.g. BY PICKING
    • B07C5/00—Sorting according to a characteristic or feature of the articles or material being sorted, e.g. by control effected by devices which detect or measure such characteristic or feature; Sorting by manually actuated devices, e.g. switches
    • B07C5/34—Sorting according to other particular properties
    • B07C5/3416—Sorting according to other particular properties according to radiation transmissivity, e.g. for light, x-rays, particle radiation
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
    • B01L3/5027—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
    • B01L3/502769—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip characterised by multiphase flow arrangements
    • B01L3/502776—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip characterised by multiphase flow arrangements specially adapted for focusing or laminating flows
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B07—SEPARATING SOLIDS FROM SOLIDS; SORTING
    • B07C—POSTAL SORTING; SORTING INDIVIDUAL ARTICLES, OR BULK MATERIAL FIT TO BE SORTED PIECE-MEAL, e.g. BY PICKING
    • B07C5/00—Sorting according to a characteristic or feature of the articles or material being sorted, e.g. by control effected by devices which detect or measure such characteristic or feature; Sorting by manually actuated devices, e.g. switches
    • B07C5/34—Sorting according to other particular properties
    • B07C5/342—Sorting according to other particular properties according to optical properties, e.g. colour
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B07—SEPARATING SOLIDS FROM SOLIDS; SORTING
    • B07C—POSTAL SORTING; SORTING INDIVIDUAL ARTICLES, OR BULK MATERIAL FIT TO BE SORTED PIECE-MEAL, e.g. BY PICKING
    • B07C5/00—Sorting according to a characteristic or feature of the articles or material being sorted, e.g. by control effected by devices which detect or measure such characteristic or feature; Sorting by manually actuated devices, e.g. switches
    • B07C5/36—Sorting apparatus characterised by the means used for distribution
    • F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
    • F16—ENGINEERING ELEMENTS AND UNITS; GENERAL MEASURES FOR PRODUCING AND MAINTAINING EFFECTIVE FUNCTIONING OF MACHINES OR INSTALLATIONS; THERMAL INSULATION IN GENERAL
    • F16K—VALVES; TAPS; COCKS; ACTUATING-FLOATS; DEVICES FOR VENTING OR AERATING
    • F16K99/00—Subject matter not provided for in other groups of this subclass
    • F16K99/0001—Microvalves
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
    • G01N15/10—Investigating individual particles
    • G01N15/14—Optical investigation techniques, e.g. flow cytometry
    • G01N15/1456—Optical investigation techniques, e.g. flow cytometry without spatial resolution of the texture or inner structure of the particle, e.g. processing of pulse signals
    • G01N15/1459—Optical investigation techniques, e.g. flow cytometry without spatial resolution of the texture or inner structure of the particle, e.g. processing of pulse signals the analysis being performed on a sample stream
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
    • G01N15/10—Investigating individual particles
    • G01N15/14—Optical investigation techniques, e.g. flow cytometry
    • G01N15/1484—Optical investigation techniques, e.g. flow cytometry microstructural devices
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/84—Systems specially adapted for particular applications
    • G01N21/85—Investigating moving fluids or granular solids
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2200/00—Solutions for specific problems relating to chemical or physical laboratory apparatus
    • B01L2200/06—Fluid handling related problems
    • B01L2200/0647—Handling flowable solids, e.g. microscopic beads, cells, particles
    • B01L2200/0652—Sorting or classification of particles or molecules
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/08—Geometry, shape and general structure
    • B01L2300/0809—Geometry, shape and general structure rectangular shaped
    • B01L2300/0816—Cards, e.g. flat sample carriers usually with flow in two horizontal directions
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/08—Geometry, shape and general structure
    • B01L2300/0809—Geometry, shape and general structure rectangular shaped
    • B01L2300/0819—Microarrays; Biochips
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/08—Geometry, shape and general structure
    • B01L2300/0861—Configuration of multiple channels and/or chambers in a single devices
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2400/00—Moving or stopping fluids
    • B01L2400/04—Moving fluids with specific forces or mechanical means
    • B01L2400/0475—Moving fluids with specific forces or mechanical means specific mechanical means and fluid pressure
    • B01L2400/0487—Moving fluids with specific forces or mechanical means specific mechanical means and fluid pressure fluid pressure, pneumatics
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
    • B01L3/5027—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
    • B01L3/502761—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip specially adapted for handling suspended solids or molecules independently from the bulk fluid flow, e.g. for trapping or sorting beads, for physically stretching molecules
    • F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
    • F16—ENGINEERING ELEMENTS AND UNITS; GENERAL MEASURES FOR PRODUCING AND MAINTAINING EFFECTIVE FUNCTIONING OF MACHINES OR INSTALLATIONS; THERMAL INSULATION IN GENERAL
    • F16K—VALVES; TAPS; COCKS; ACTUATING-FLOATS; DEVICES FOR VENTING OR AERATING
    • F16K99/00—Subject matter not provided for in other groups of this subclass
    • F16K99/0001—Microvalves
    • F16K99/0003—Constructional types of microvalves; Details of the cutting-off member
    • F16K99/0028—Valves having multiple inlets or outlets
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
    • G01N15/10—Investigating individual particles
    • G01N15/14—Optical investigation techniques, e.g. flow cytometry
    • G01N15/149—Optical investigation techniques, e.g. flow cytometry specially adapted for sorting particles, e.g. by their size or optical properties
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
    • G01N15/10—Investigating individual particles
    • G01N2015/1006—Investigating individual particles for cytology

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Dispersion Chemistry (AREA)
  • Analytical Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Biochemistry (AREA)
  • General Physics & Mathematics (AREA)
  • Immunology (AREA)
  • Clinical Laboratory Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • General Engineering & Computer Science (AREA)
  • Hematology (AREA)
  • Toxicology (AREA)
  • Mechanical Engineering (AREA)
  • Automatic Analysis And Handling Materials Therefor (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Separation Of Solids By Using Liquids Or Pneumatic Power (AREA)
JP2012180317A 2012-08-16 2012-08-16 微小粒子分取方法及び微小粒子分取用マイクロチップ Active JP5910412B2 (ja)

Priority Applications (7)

Application Number Priority Date Filing Date Title
JP2012180317A JP5910412B2 (ja) 2012-08-16 2012-08-16 微小粒子分取方法及び微小粒子分取用マイクロチップ
CN201310347353.4A CN103586221B (zh) 2012-08-16 2013-08-09 微粒分选方法和用于微粒分选的微芯片
CN201611205723.0A CN107051911B (zh) 2012-08-16 2013-08-09 用于微粒分选的微芯片、装置及配套元件
US13/963,188 US9737912B2 (en) 2012-08-16 2013-08-09 Microparticle sorting method and microchip for sorting microparticles
US15/658,693 US10562074B2 (en) 2012-08-16 2017-07-25 Microparticle sorting method and microchip for sorting microparticles
US16/733,601 US11148173B2 (en) 2012-08-16 2020-01-03 Microparticle sorting method and microchip for sorting microparticles
US17/469,335 US11666946B2 (en) 2012-08-16 2021-09-08 Microparticle sorting method and microchip for sorting microparticles

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP2012180317A JP5910412B2 (ja) 2012-08-16 2012-08-16 微小粒子分取方法及び微小粒子分取用マイクロチップ

Publications (3)

Publication Number Publication Date
JP2014036604A JP2014036604A (ja) 2014-02-27
JP2014036604A5 JP2014036604A5 (enExample) 2015-03-05
JP5910412B2 true JP5910412B2 (ja) 2016-04-27

Family

ID=50076657

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2012180317A Active JP5910412B2 (ja) 2012-08-16 2012-08-16 微小粒子分取方法及び微小粒子分取用マイクロチップ

Country Status (3)

Country Link
US (4) US9737912B2 (enExample)
JP (1) JP5910412B2 (enExample)
CN (2) CN103586221B (enExample)

Families Citing this family (42)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US10670514B2 (en) * 2014-10-01 2020-06-02 Water Optics Technology Pte. Ltd. Sensor for particle detection in a fluid
WO2016116535A1 (en) * 2015-01-21 2016-07-28 Sbt Aqua Aps Microfluidic particle analysis device
CN105510191B (zh) * 2015-11-19 2019-02-05 江苏卓微生物科技有限公司 流式微粒检测方法
JP6953679B2 (ja) 2016-03-30 2021-10-27 ソニーグループ株式会社 試料分取キット、試料分取装置
CN109073532B (zh) 2016-05-17 2021-10-22 索尼公司 颗粒提取装置和颗粒提取方法
CN107442186B (zh) * 2016-05-31 2020-06-09 深圳汇芯生物医疗科技有限公司 微流控芯片、基于微流控芯片的分析装置及分析方法
CN108251291A (zh) * 2016-12-29 2018-07-06 上海新微技术研发中心有限公司 一种细胞筛选装置和细胞筛选方法
JP6919215B2 (ja) * 2017-02-17 2021-08-18 ソニーグループ株式会社 マイクロチップ及び微小粒子分取装置
WO2018163943A1 (ja) 2017-03-08 2018-09-13 ソニー株式会社 細胞サンプル液送液用バッグ、細胞サンプル液送液方法、及び細胞サンプル液送液装置
WO2018179647A1 (ja) 2017-03-31 2018-10-04 ソニー株式会社 流路ユニット及び微小粒子分析装置
WO2018216269A1 (ja) 2017-05-24 2018-11-29 ソニー株式会社 微小粒子の吸引条件の最適化方法及び微小粒子分取装置
EP3633347B1 (en) 2017-05-26 2023-07-19 Sony Group Corporation Method for optimizing suction conditions for microparticles, and microparticle separation device
WO2019006190A1 (en) 2017-06-28 2019-01-03 Bio-Rad Laboratories, Inc. SYSTEM AND METHOD FOR DROPLELET DETECTION
WO2019089979A1 (en) 2017-11-01 2019-05-09 Bio-Rad Laboratories, Inc. Microfluidic system and method for arranging objects
JP7167935B2 (ja) * 2017-11-14 2022-11-09 ソニーグループ株式会社 微粒子分取用マイクロチップ及び微粒子分取装置
CN111771116B (zh) 2018-03-02 2024-03-05 索尼公司 用于优化微粒吸入条件的方法、微粒分选装置和系统
JP7276551B2 (ja) * 2018-03-27 2023-05-18 ソニーグループ株式会社 微小粒子分取方法、微小粒子分取用プログラム及び微小粒子分取用システム
JP7059747B2 (ja) 2018-03-27 2022-04-26 ソニーグループ株式会社 微小粒子分取方法、微小粒子分取用プログラム及び微小粒子分取用システム
WO2019230489A1 (ja) 2018-06-01 2019-12-05 ソニー株式会社 マイクロチップ及びサンプル分取キット
WO2020054196A1 (ja) 2018-09-10 2020-03-19 ソニー株式会社 微小粒子分取用流路ユニット及び微小粒子分取装置
JP7338336B2 (ja) 2018-09-10 2023-09-05 ソニーグループ株式会社 微小粒子分取装置、細胞治療薬製造装置、微小粒子分取方法、及びプログラム
JP7326787B2 (ja) * 2019-03-15 2023-08-16 株式会社リコー 選別装置
CN110343603B (zh) * 2019-07-04 2024-10-15 中国科学院苏州生物医学工程技术研究所 利用鞘液逆流防止细胞阻塞的微流控芯片
CN110339877B (zh) * 2019-07-04 2024-05-17 中国科学院苏州生物医学工程技术研究所 具有三维聚焦功能的单层微流控芯片
JP7388131B2 (ja) * 2019-10-31 2023-11-29 ソニーグループ株式会社 微小粒子回収方法、微小粒子分取用マイクロチップ、微小粒子回収装置、エマルションの製造方法、及びエマルション
US12371652B2 (en) 2019-11-05 2025-07-29 Sony Group Corporation Priming method of microparticle sorting microchip, microparticle sorting method, microparticle sorting device, and program
JP2021076455A (ja) 2019-11-07 2021-05-20 ソニー株式会社 分取制御装置、該分取制御装置を用いた粒子分取装置及び粒子分取システム、並びに分取制御方法、及び制御プログラム
USD1039403S1 (en) * 2019-11-20 2024-08-20 Sony Corporation Disposable kit for flow cytometer
JP7528950B2 (ja) * 2019-11-20 2024-08-06 ソニーグループ株式会社 マイクロチップ、サンプル分取キット及び微小粒子分取装置
CN111151034B (zh) * 2020-01-03 2021-11-09 中国核电工程有限公司 流量调节装置及混合澄清槽
JP7694568B2 (ja) * 2020-07-28 2025-06-18 ソニーグループ株式会社 微小粒子分取装置及び微小粒子分取方法
US20230273108A1 (en) * 2020-07-28 2023-08-31 Sony Group Corporation Microparticle analysis device, microparticle sorting system, and microparticle analysis method
JPWO2022209374A1 (enExample) 2021-03-31 2022-10-06
WO2022216275A1 (en) * 2021-04-06 2022-10-13 Hewlett-Packard Development Company, L.P. Microfluidic device channel splitting
CN114073997B (zh) * 2021-11-30 2022-07-05 南京林业大学 一种低流速下实现细胞快速精准分选的微流控芯片及方法
EP4528249A4 (en) * 2022-05-16 2025-08-27 Sony Group Corp MICROPARTICLE ISOLATION DEVICE AND MICROPARTICLE ISOLATION METHOD
US12186748B2 (en) 2022-06-24 2025-01-07 Hewlett-Packard Development Company, L.P. Self-priming microfluidic structures
KR102515270B1 (ko) * 2022-08-24 2023-03-29 주식회사 팍스웰 바이오 칩을 이용한 세포 분석 장치
KR102553905B1 (ko) * 2022-08-24 2023-07-10 주식회사 팍스웰 세포 분석을 위한 바이오 칩
CN115555068B (zh) * 2022-11-08 2024-09-27 余姚市机器人研究中心 一种阈值可调的微流控液滴尺寸分选装置
KR102874554B1 (ko) * 2023-10-19 2025-10-22 주식회사 팍스웰 세포 분석을 위한 유세포 분석기
CN120082423B (zh) * 2025-05-06 2025-09-12 杭州谱康医学科技有限公司 微粒分选装置和方法

Family Cites Families (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU4113297A (en) * 1996-09-04 1998-03-26 Technical University Of Denmark A micro flow system for particle separation and analysis
US6976590B2 (en) * 2002-06-24 2005-12-20 Cytonome, Inc. Method and apparatus for sorting particles
BR0309321A (pt) * 2002-04-17 2005-03-29 Cytonome Inc Método e aparelho para selecionar partìculas
WO2003102737A2 (en) * 2002-06-04 2003-12-11 Protasis Corporation Method and device for ultrasonically manipulating particles within a fluid
WO2004025266A2 (en) * 2002-09-16 2004-03-25 Cytonome, Inc Method and apparatus for sorting particles
CN1735466A (zh) * 2002-09-16 2006-02-15 塞通诺米公司 颗粒分选的设备和方法
JP2005214691A (ja) * 2004-01-28 2005-08-11 Noritake Co Ltd フローセル装置
US7392908B2 (en) * 2005-01-12 2008-07-01 Beckman Coulter, Inc. Methods and apparatus for sorting particles hydraulically
US7355696B2 (en) * 2005-02-01 2008-04-08 Arryx, Inc Method and apparatus for sorting cells
JP4539707B2 (ja) 2007-10-25 2010-09-08 ソニー株式会社 微小粒子分取装置及び微小粒子分取用基板、並びに微小粒子分取方法
WO2009119698A1 (ja) * 2008-03-24 2009-10-01 日本電気株式会社 マイクロチップの流路制御機構
WO2009131677A1 (en) * 2008-04-25 2009-10-29 Claros Diagnostics, Inc. Flow control in microfluidic systems
JP2010038866A (ja) * 2008-08-08 2010-02-18 Sony Corp マイクロチップ、微小粒子分取装置及び送流方法
US9134221B2 (en) * 2009-03-10 2015-09-15 The Regents Of The University Of California Fluidic flow cytometry devices and particle sensing based on signal-encoding
JP2011145185A (ja) * 2010-01-15 2011-07-28 Sony Corp 流路構造、マイクロチップ及び送流方法
US8941062B2 (en) * 2010-11-16 2015-01-27 1087 Systems, Inc. System for identifying and sorting living cells
JP5720233B2 (ja) * 2010-12-17 2015-05-20 ソニー株式会社 マイクロチップ及び微小粒子分取装置

Also Published As

Publication number Publication date
US20170320104A1 (en) 2017-11-09
JP2014036604A (ja) 2014-02-27
US20200139408A1 (en) 2020-05-07
US20140048458A1 (en) 2014-02-20
US10562074B2 (en) 2020-02-18
US11148173B2 (en) 2021-10-19
US9737912B2 (en) 2017-08-22
CN107051911A (zh) 2017-08-18
US11666946B2 (en) 2023-06-06
CN103586221A (zh) 2014-02-19
CN103586221B (zh) 2017-03-01
US20210402440A1 (en) 2021-12-30
CN107051911B (zh) 2019-06-14

Similar Documents

Publication Publication Date Title
JP5910412B2 (ja) 微小粒子分取方法及び微小粒子分取用マイクロチップ
JP6172147B2 (ja) 微小粒子分取装置及び微小粒子分取方法
US9018556B2 (en) Microparticle sorting method
JP6003020B2 (ja) マイクロチップ及び微小粒子分析装置
JP7298652B2 (ja) 粒子分取装置及び粒子分取方法
JP7167935B2 (ja) 微粒子分取用マイクロチップ及び微粒子分取装置
JP2019184337A (ja) マイクロチップ、微小粒子測定装置、及び微小粒子測定方法
JP7207394B2 (ja) 微小粒子の吸引条件の最適化方法、微小粒子分取用装置、微小粒子分取用システム及び微小粒子分取用プログラム
JP5316530B2 (ja) マイクロチップとその流路構造
JP7287399B2 (ja) 微小粒子分取用流路ユニット及び微小粒子分取装置
JP6708978B2 (ja) マイクロチップ及び微小粒子分析装置
JP6965953B2 (ja) マイクロチップ及び微小粒子分析装置
JP7632298B2 (ja) 粒子分取キット
CN102564925B (zh) 微芯片和微粒分取装置
CN102564925A (zh) 微芯片和微粒分取装置

Legal Events

Date Code Title Description
A521 Request for written amendment filed

Free format text: JAPANESE INTERMEDIATE CODE: A523

Effective date: 20150116

A621 Written request for application examination

Free format text: JAPANESE INTERMEDIATE CODE: A621

Effective date: 20150116

A977 Report on retrieval

Free format text: JAPANESE INTERMEDIATE CODE: A971007

Effective date: 20151028

A131 Notification of reasons for refusal

Free format text: JAPANESE INTERMEDIATE CODE: A131

Effective date: 20151104

A521 Request for written amendment filed

Free format text: JAPANESE INTERMEDIATE CODE: A523

Effective date: 20151130

TRDD Decision of grant or rejection written
A01 Written decision to grant a patent or to grant a registration (utility model)

Free format text: JAPANESE INTERMEDIATE CODE: A01

Effective date: 20160301

A61 First payment of annual fees (during grant procedure)

Free format text: JAPANESE INTERMEDIATE CODE: A61

Effective date: 20160314

R151 Written notification of patent or utility model registration

Ref document number: 5910412

Country of ref document: JP

Free format text: JAPANESE INTERMEDIATE CODE: R151

R250 Receipt of annual fees

Free format text: JAPANESE INTERMEDIATE CODE: R250

R250 Receipt of annual fees

Free format text: JAPANESE INTERMEDIATE CODE: R250