JP5851022B2 - アルツハイマー病を処置するための組成物および方法 - Google Patents

アルツハイマー病を処置するための組成物および方法 Download PDF

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JP5851022B2
JP5851022B2 JP2014510427A JP2014510427A JP5851022B2 JP 5851022 B2 JP5851022 B2 JP 5851022B2 JP 2014510427 A JP2014510427 A JP 2014510427A JP 2014510427 A JP2014510427 A JP 2014510427A JP 5851022 B2 JP5851022 B2 JP 5851022B2
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inhibitor
patient
disease
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alzheimer
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JP2014513694A (ja
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ジョン ジャハンガー アラム，
ジョン ジャハンガー アラム，
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イーアイピー ファーマ， エルエルシー
イーアイピー ファーマ， エルエルシー
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    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
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    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4418—Non condensed pyridines; Hydrogenated derivatives thereof having a carbocyclic group directly attached to the heterocyclic ring, e.g. cyproheptadine
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    • A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
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    • A61K31/5375—1,4-Oxazines, e.g. morpholine
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    • C07D211/08—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms
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    • C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
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JP2014510427A 2011-05-09 2012-05-09 アルツハイマー病を処置するための組成物および方法 Expired - Fee Related JP5851022B2 (ja)

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AU2011343039B2 (en) 2010-12-14 2017-03-02 Electrophoretics Limited Casein kinase 1delta (CK1delta) inhibitors
JP5851022B2 (ja) 2011-05-09 2016-02-03 イーアイピー ファーマ， エルエルシー アルツハイマー病を処置するための組成物および方法
WO2013162027A1 (ja) * 2012-04-27 2013-10-31 学校法人 慶應義塾 神経分化促進剤
EP3842424B1 (en) 2013-03-15 2024-12-11 The Trustees of Columbia University in the City of New York Map kinase modulators and uses thereof in the tretament of tauopathies
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