JP5826494B2 - 試料の構造を空間的に高分解能で結像するための装置および方法 - Google Patents

試料の構造を空間的に高分解能で結像するための装置および方法 Download PDF

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JP5826494B2
JP5826494B2 JP2010546236A JP2010546236A JP5826494B2 JP 5826494 B2 JP5826494 B2 JP 5826494B2 JP 2010546236 A JP2010546236 A JP 2010546236A JP 2010546236 A JP2010546236 A JP 2010546236A JP 5826494 B2 JP5826494 B2 JP 5826494B2
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light
molecules
excitation
objective lens
switching
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JP2011511966A5 (enExample
JP2011511966A (ja
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ヴォレシェンスキー、ラルフ
リッペルト、ヘルムート
パワー、クリストファー
ラット、ベンノ
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Carl Zeiss Microscopy GmbH
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    • G—PHYSICS
    • G02—OPTICS
    • G02B—OPTICAL ELEMENTS, SYSTEMS OR APPARATUS
    • G02B21/00—Microscopes
    • G02B21/0004—Microscopes specially adapted for specific applications
    • G02B21/002—Scanning microscopes
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
    • G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
    • G01N21/64—Fluorescence; Phosphorescence
    • G01N21/645—Specially adapted constructive features of fluorimeters
    • G01N21/6456—Spatial resolved fluorescence measurements; Imaging
    • G01N21/6458—Fluorescence microscopy
    • G—PHYSICS
    • G02—OPTICS
    • G02B—OPTICAL ELEMENTS, SYSTEMS OR APPARATUS
    • G02B21/00—Microscopes
    • G02B21/06—Means for illuminating specimens
    • G02B21/08—Condensers
    • G02B21/10—Condensers affording dark-field illumination
    • G—PHYSICS
    • G02—OPTICS
    • G02B—OPTICAL ELEMENTS, SYSTEMS OR APPARATUS
    • G02B21/00—Microscopes
    • G02B21/36—Microscopes arranged for photographic purposes or projection purposes or digital imaging or video purposes including associated control and data processing arrangements
    • G02B21/365—Control or image processing arrangements for digital or video microscopes
    • G02B21/367—Control or image processing arrangements for digital or video microscopes providing an output produced by processing a plurality of individual source images, e.g. image tiling, montage, composite images, depth sectioning, image comparison
    • G—PHYSICS
    • G02—OPTICS
    • G02B—OPTICAL ELEMENTS, SYSTEMS OR APPARATUS
    • G02B27/00—Optical systems or apparatus not provided for by any of the groups G02B1/00 - G02B26/00, G02B30/00
    • G02B27/58—Optics for apodization or superresolution; Optical synthetic aperture systems

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  • Physics & Mathematics (AREA)
  • General Physics & Mathematics (AREA)
  • Chemical & Material Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Optics & Photonics (AREA)
  • Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Pathology (AREA)
  • Engineering & Computer Science (AREA)
  • Multimedia (AREA)
  • Computer Vision & Pattern Recognition (AREA)
  • Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
  • Microscoopes, Condenser (AREA)
JP2010546236A 2008-02-13 2009-02-03 試料の構造を空間的に高分解能で結像するための装置および方法 Active JP5826494B2 (ja)

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DE102008009216.9 2008-02-13
DE102008009216A DE102008009216A1 (de) 2008-02-13 2008-02-13 Vorrichtung und Verfahren zum räumlich hochauflösenden Abbilden einer Struktur einer Probe
PCT/EP2009/000677 WO2009100830A1 (de) 2008-02-13 2009-02-03 Vorrichtung und verfahren zum räumlichen hochauflösenden abbilden einer struktur einer probe

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JP2011511966A5 JP2011511966A5 (enExample) 2012-06-07
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US (1) US8362448B2 (enExample)
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DE (1) DE102008009216A1 (enExample)
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JP2015215629A (ja) 2015-12-03
WO2009100830A1 (de) 2009-08-20
EP2245494B1 (de) 2021-01-27
DE102008009216A1 (de) 2009-08-20
US20110036996A1 (en) 2011-02-17
EP2245494A1 (de) 2010-11-03
JP2011511966A (ja) 2011-04-14
US8362448B2 (en) 2013-01-29
JP6039760B2 (ja) 2016-12-07

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