JP5808882B2 - 分子へのアミノ酸の部位特異的な組み込み - Google Patents

分子へのアミノ酸の部位特異的な組み込み Download PDF

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JP5808882B2
JP5808882B2 JP2008557434A JP2008557434A JP5808882B2 JP 5808882 B2 JP5808882 B2 JP 5808882B2 JP 2008557434 A JP2008557434 A JP 2008557434A JP 2008557434 A JP2008557434 A JP 2008557434A JP 5808882 B2 JP5808882 B2 JP 5808882B2
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amino acid
trna
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amino acids
protein
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JP2009528824A5 (enExample
JP2009528824A (ja
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ピン ワン，
ピン ワン，
インチャン クウォン，
インチャン クウォン，
スーチン ソン，
スーチン ソン，
イー タン，
イー タン，
デイビッド エー． ティレル，
デイビッド エー． ティレル，
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カリフォルニア インスティテュート オブ テクノロジー
カリフォルニア インスティテュート オブ テクノロジー
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    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
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    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/93—Ligases (6)
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    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
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    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
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    • C12N15/67—General methods for enhancing the expression
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    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/70—Vectors or expression systems specially adapted for E. coli

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JP2008557434A 2006-03-03 2007-03-05 分子へのアミノ酸の部位特異的な組み込み Active JP5808882B2 (ja)

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US77937606P 2006-03-03 2006-03-03
US77937506P 2006-03-03 2006-03-03
US60/779,375 2006-03-03
US60/779,376 2006-03-03
PCT/US2007/005581 WO2007103307A2 (en) 2006-03-03 2007-03-05 Site-specific incorporation of amino acids into molecules

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US11492369B2 (en) 2017-12-15 2022-11-08 Chugai Seiyaku Kabushiki Kaisha Method for producing peptide, and method for processing bases
US11542299B2 (en) 2017-06-09 2023-01-03 Chugai Seiyaku Kabushiki Kaisha Method for synthesizing peptide containing N-substituted amino acid
US11732002B2 (en) 2018-11-30 2023-08-22 Chugai Seiyaku Kabushiki Kaisha Deprotection method and resin removal method in solid-phase reaction for peptide compound or amide compound, and method for producing peptide compound
US12071396B2 (en) 2019-03-15 2024-08-27 Chugai Seiyaku Kabushiki Kaisha Method for preparing aromatic amino acid derivative
US12163134B2 (en) 2015-03-13 2024-12-10 Chugai Seiyaku Kabushiki Kaisha Modified aminoacyl-tRNA synthetase and use thereof
US12312297B2 (en) 2018-11-07 2025-05-27 Chugai Seiyaku Kabushiki Kaisha O-substituted serine derivative production method
US12371454B2 (en) 2019-11-07 2025-07-29 Chugai Seiyaku Kabushiki Kaisha Cyclic peptide compound having Kras inhibitory action
US12391971B2 (en) 2017-01-31 2025-08-19 Chugai Seiyaku Kabushiki Kaisha Method for synthesizing peptides in cell-free translation system

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US12163134B2 (en) 2015-03-13 2024-12-10 Chugai Seiyaku Kabushiki Kaisha Modified aminoacyl-tRNA synthetase and use thereof
US12391971B2 (en) 2017-01-31 2025-08-19 Chugai Seiyaku Kabushiki Kaisha Method for synthesizing peptides in cell-free translation system
US11542299B2 (en) 2017-06-09 2023-01-03 Chugai Seiyaku Kabushiki Kaisha Method for synthesizing peptide containing N-substituted amino acid
US11787836B2 (en) 2017-06-09 2023-10-17 Chugai Seiyaku Kabushiki Kaisha Method for synthesizing peptide containing N-substituted amino acid
US12281141B2 (en) 2017-06-09 2025-04-22 Chugai Seiyaku Kabushiki Kaisha Method for synthesizing peptide containing N-substituted amino acid
US11492369B2 (en) 2017-12-15 2022-11-08 Chugai Seiyaku Kabushiki Kaisha Method for producing peptide, and method for processing bases
US12312297B2 (en) 2018-11-07 2025-05-27 Chugai Seiyaku Kabushiki Kaisha O-substituted serine derivative production method
US11732002B2 (en) 2018-11-30 2023-08-22 Chugai Seiyaku Kabushiki Kaisha Deprotection method and resin removal method in solid-phase reaction for peptide compound or amide compound, and method for producing peptide compound
US12331072B2 (en) 2018-11-30 2025-06-17 Chugai Seiyaku Kabushiki Kaisha Deprotection method and resin removal method in solid-phase reaction for peptide compound or amide compound, and method for producing peptide compound
US12071396B2 (en) 2019-03-15 2024-08-27 Chugai Seiyaku Kabushiki Kaisha Method for preparing aromatic amino acid derivative
US12371454B2 (en) 2019-11-07 2025-07-29 Chugai Seiyaku Kabushiki Kaisha Cyclic peptide compound having Kras inhibitory action

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EP1999259A2 (en) 2008-12-10
US8518666B2 (en) 2013-08-27
US20080044854A1 (en) 2008-02-21
AU2014202733A1 (en) 2014-06-12
WO2007103307B1 (en) 2008-05-02
US20140045261A1 (en) 2014-02-13
US8980581B2 (en) 2015-03-17
PT1999259E (pt) 2014-09-24
EP1999259B1 (en) 2014-06-25
JP2009528824A (ja) 2009-08-13
DK1999259T3 (da) 2014-10-06
WO2007103307A2 (en) 2007-09-13
CA2644474A1 (en) 2007-09-13
AU2007224019A1 (en) 2007-09-13
WO2007103307A3 (en) 2008-03-13
JP2013146274A (ja) 2013-08-01
SI1999259T1 (sl) 2014-11-28
ES2504521T3 (es) 2014-10-08
PL1999259T3 (pl) 2015-01-30

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