JP5797376B2 - 定量吸入器を用いたトレプロスチニル投与 - Google Patents

定量吸入器を用いたトレプロスチニル投与 Download PDF

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Publication number
JP5797376B2
JP5797376B2 JP2009511194A JP2009511194A JP5797376B2 JP 5797376 B2 JP5797376 B2 JP 5797376B2 JP 2009511194 A JP2009511194 A JP 2009511194A JP 2009511194 A JP2009511194 A JP 2009511194A JP 5797376 B2 JP5797376 B2 JP 5797376B2
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Prior art keywords
treprostinil
tre
inhalation
pulmonary
acceptable salt
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Japanese (ja)
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JP2009537246A (ja
JP2009537246A5 (enExample
Inventor
オルシェウスキー，ホルスト
ロシーニョ，ロバート
ルビン，ルイス，ジェイ．
シュメール，トーマス
シーガー，ワーナー
ステリット，カール
ヴォスウインケル，ロバート
Original Assignee
ユナイテッド セラピューティクス コーポレーション
ユナイテッド セラピューティクス コーポレーション
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Application filed by ユナイテッド セラピューティクス コーポレーション, ユナイテッド セラピューティクス コーポレーション filed Critical ユナイテッド セラピューティクス コーポレーション
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/557—Eicosanoids, e.g. leukotrienes or prostaglandins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/192—Carboxylic acids, e.g. valproic acid having aromatic groups, e.g. sulindac, 2-aryl-propionic acids, ethacrynic acid 
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/007—Pulmonary tract; Aromatherapy
    • A61K9/0073—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
    • A61K9/0078—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy for inhalation via a nebulizer such as a jet nebulizer, ultrasonic nebulizer, e.g. in the form of aqueous drug solutions or dispersions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/007—Pulmonary tract; Aromatherapy
    • A61K9/0073—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
    • A61K9/008—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy comprising drug dissolved or suspended in liquid propellant for inhalation via a pressurized metered dose inhaler [MDI]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/12—Aerosols; Foams
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Pulmonology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Otolaryngology (AREA)
  • Dispersion Chemistry (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
JP2009511194A 2006-05-15 2007-05-14 定量吸入器を用いたトレプロスチニル投与 Active JP5797376B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US80001606P 2006-05-15 2006-05-15
US60/800,016 2006-05-15
PCT/US2007/068884 WO2007134292A2 (en) 2006-05-15 2007-05-14 Treprostinil administration using a metered dose inhaler

Related Child Applications (2)

Application Number Title Priority Date Filing Date
JP2013185229A Division JP2014114269A (ja) 2006-05-15 2013-09-06 定量吸入器を用いたトレプロスチニル投与
JP2015142794A Division JP2016006066A (ja) 2006-05-15 2015-07-17 定量吸入器を用いたトレプロスチニル投与

Publications (3)

Publication Number Publication Date
JP2009537246A JP2009537246A (ja) 2009-10-29
JP2009537246A5 JP2009537246A5 (enExample) 2010-06-17
JP5797376B2 true JP5797376B2 (ja) 2015-10-21

Family

ID=38544006

Family Applications (4)

Application Number Title Priority Date Filing Date
JP2009511194A Active JP5797376B2 (ja) 2006-05-15 2007-05-14 定量吸入器を用いたトレプロスチニル投与
JP2013185229A Withdrawn JP2014114269A (ja) 2006-05-15 2013-09-06 定量吸入器を用いたトレプロスチニル投与
JP2015142794A Withdrawn JP2016006066A (ja) 2006-05-15 2015-07-17 定量吸入器を用いたトレプロスチニル投与
JP2019038370A Pending JP2019112434A (ja) 2006-05-15 2019-03-04 定量吸入器を用いたトレプロスチニル投与

Family Applications After (3)

Application Number Title Priority Date Filing Date
JP2013185229A Withdrawn JP2014114269A (ja) 2006-05-15 2013-09-06 定量吸入器を用いたトレプロスチニル投与
JP2015142794A Withdrawn JP2016006066A (ja) 2006-05-15 2015-07-17 定量吸入器を用いたトレプロスチニル投与
JP2019038370A Pending JP2019112434A (ja) 2006-05-15 2019-03-04 定量吸入器を用いたトレプロスチニル投与

Country Status (8)

Country Link
US (10) US20080200449A1 (enExample)
EP (1) EP2026816B1 (enExample)
JP (4) JP5797376B2 (enExample)
KR (1) KR101390579B1 (enExample)
CN (1) CN101495122B (enExample)
CA (1) CA2654492C (enExample)
ES (1) ES2707548T3 (enExample)
WO (1) WO2007134292A2 (enExample)

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US9358240B2 (en) 2016-06-07
US20100076083A1 (en) 2010-03-25
US20200171044A1 (en) 2020-06-04
US10716793B2 (en) 2020-07-21
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US20220323459A1 (en) 2022-10-13
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US20220218720A1 (en) 2022-07-14
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US9339507B2 (en) 2016-05-17
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