JP5796014B2 - がんを処置するためのトール様受容体およびトール様受容体アゴニストの使用 - Google Patents
がんを処置するためのトール様受容体およびトール様受容体アゴニストの使用 Download PDFInfo
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- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
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- C12N2830/00—Vector systems having a special element relevant for transcription
- C12N2830/20—Vector systems having a special element relevant for transcription transcription of more than one cistron
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| US24959609P | 2009-10-07 | 2009-10-07 | |
| US61/249,596 | 2009-10-07 | ||
| PCT/US2010/051646 WO2011044246A1 (en) | 2009-10-06 | 2010-10-06 | Use of toll-like receptor and agonist for treating cancer |
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| JP2015128384A Division JP2015165821A (ja) | 2009-10-06 | 2015-06-26 | がんを処置するためのトール様受容体およびトール様受容体アゴニストの使用 |
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| JP2015128384A Pending JP2015165821A (ja) | 2009-10-06 | 2015-06-26 | がんを処置するためのトール様受容体およびトール様受容体アゴニストの使用 |
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| EP (1) | EP2486134B1 (https=) |
| JP (2) | JP5796014B2 (https=) |
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| WO (1) | WO2011044246A1 (https=) |
| ZA (1) | ZA201202500B (https=) |
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| Publication number | Priority date | Publication date | Assignee | Title |
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| EP2460534A1 (en) | 2004-12-22 | 2012-06-06 | Cleveland Clinic Foundation | Flagellin related polypeptides and uses thereof |
| CN102170911B (zh) | 2008-08-01 | 2014-07-02 | 克里夫兰生物实验室公司 | 用于治疗再灌注损伤的方法 |
| WO2012097012A1 (en) | 2011-01-10 | 2012-07-19 | Cleveland Biolabs, Inc. | Use of toll-like receptor agonist for treating cancer |
| WO2014098649A1 (en) * | 2012-12-18 | 2014-06-26 | Obschestvo S Ogranichennoy Otvetstvennostyu "Panacela Labs" | Compositions and methods using toll-like receptor 5 and toll-like receptor agonist |
| WO2015080631A1 (en) * | 2013-11-27 | 2015-06-04 | Obschestvo S Ogranichennoy Otvetstvennost`Yu "Panacela Labs" | Improved expression vector for toll-like receptor and agonist and use for treating cancer |
| US10202426B2 (en) | 2014-07-30 | 2019-02-12 | Genome Protection, Inc. | Flagellin compositions and uses |
| EP3925968A3 (en) | 2014-10-07 | 2022-03-02 | Cytlimic Inc. | Hsp70-derived peptide, pharmaceutical composition for treating or preventing cancer using same, immunity inducer, and method for producing antigen-presenting cell |
| US10183056B2 (en) | 2014-10-16 | 2019-01-22 | Cleveland Biolabs, Inc. | Methods and compositions for the treatment of radiation-related disorders |
| CN113388021A (zh) | 2015-03-09 | 2021-09-14 | Cytlimic公司 | 源于gpc3的肽、使用其的医药组合物、免疫诱导剂、及抗原呈递细胞的制造方法 |
| RU2709015C2 (ru) * | 2015-04-07 | 2019-12-13 | Ситлимик Инк. | Лекарственное средство |
| KR101634380B1 (ko) | 2015-06-23 | 2016-06-28 | 한국생산기술연구원 | Tlr5 아고니스트 단백질의 생산방법 |
| CN105801709B (zh) * | 2016-04-29 | 2019-10-08 | 北京纽莱福生物科技有限公司 | CBLB502-Fc融合蛋白及其制备方法 |
| US11291718B2 (en) | 2016-10-11 | 2022-04-05 | Cytlimic Inc. | Method for treating cancer by administering a toll-like receptor agonist and LAG-3 IgG fusion protein |
| WO2018088933A1 (en) * | 2016-11-14 | 2018-05-17 | Limited Liability Company "Panacela Labs" | Anti-tumor effects of a viral vector encoding a toll-like receptor and a toll-like receptor agonist |
| CN113608416B (zh) * | 2016-12-28 | 2024-07-30 | Asml荷兰有限公司 | 量测图像与设计之间的模拟辅助的对准 |
| WO2018210279A1 (zh) * | 2017-05-16 | 2018-11-22 | 科济生物医药（上海）有限公司 | Toll样受体激动剂与免疫效应细胞的联用 |
| WO2019018768A1 (en) | 2017-07-20 | 2019-01-24 | Spogen Biotech Inc. | BIOACTIVE POLYPEPTIDES FOR PLANT PROTECTION, GROWTH AND PRODUCTIVITY ENHANCEMENTS |
| WO2019180051A1 (en) | 2018-03-19 | 2019-09-26 | 4D Pharma Research Limited | Compositions comprising bacterial strains |
| US12440536B2 (en) | 2018-05-18 | 2025-10-14 | The University Of Hong Kong | Compositions of toll-like receptor 5 (TLR5) agonist and methods of use thereof |
| EP3841112A1 (en) | 2018-08-24 | 2021-06-30 | Codiak BioSciences, Inc. | Extracellular vesicles targeting dendritic cells and uses thereof |
| CA3128386A1 (en) | 2019-02-04 | 2020-08-13 | Codiak Biosciences, Inc. | Membrane protein scaffolds for exosome engineering |
| EP3941607A1 (en) | 2019-03-21 | 2022-01-26 | Codiak BioSciences, Inc. | Process for preparing extracellular vesicles |
| BR112021018694A2 (pt) | 2019-03-21 | 2021-11-30 | Codiak Biosciences Inc | Vesículas extracelulares para distribuição de vacina |
| US20240108747A1 (en) | 2019-03-21 | 2024-04-04 | Lonza Sales Ag | Extracellular vesicle conjugates and uses thereof |
| EP3994158A1 (en) | 2019-07-03 | 2022-05-11 | Codiak BioSciences, Inc. | Extracellular vesicles targeting t cells and uses thereof |
| MX2022003570A (es) | 2019-09-25 | 2022-07-11 | Codiak Biosciences Inc | Composiciones de vesícula extracelular. |
| US20230114434A1 (en) | 2020-03-13 | 2023-04-13 | Codiak Biosciences, Inc. | Extracellular vesicles for treating neurological disorders |
| JP2023518414A (ja) | 2020-03-20 | 2023-05-01 | コディアック バイオサイエンシーズ， インコーポレイテッド | 治療のための細胞外小胞 |
| WO2021237100A1 (en) | 2020-05-21 | 2021-11-25 | Codiak Biosciences, Inc. | Methods of targeting extracellular vesicles to lung |
| WO2021246666A1 (ko) * | 2020-06-04 | 2021-12-09 | 가톨릭대학교 산학협력단 | 플라젤린으로부터 유도된 tlr5 작용제를 유효성분으로 포함하는 항암제 조성물 |
| US20230220068A1 (en) | 2020-06-05 | 2023-07-13 | Codiak Biosciences, Inc. | Anti-transferrin extracellular vesicles |
| WO2022066883A1 (en) | 2020-09-23 | 2022-03-31 | Codiak Biosciences, Inc. | Extracellular vesicles comprising kras antigens and uses thereof |
| WO2022066928A2 (en) | 2020-09-23 | 2022-03-31 | Codiak Biosciences, Inc. | Process for preparing extracellular vesicles |
| US20240082389A1 (en) | 2020-09-23 | 2024-03-14 | Lonza Sales Ag | Methods of producing extracellular vesicles |
| WO2025196053A1 (en) * | 2024-03-18 | 2025-09-25 | Istituto Europeo Di Oncologia S.R.L. | Flagellin-related peptides and uses thereof |
| EP4620482A1 (en) * | 2024-03-18 | 2025-09-24 | Istituto Europeo di Oncologia S.r.l. | Flagellin-related peptides and uses thereof |
Family Cites Families (4)
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| US8703146B2 (en) * | 2001-04-20 | 2014-04-22 | Institute For Systems Biology | Toll-like receptor 5 ligands and methods of use |
| EP2460534A1 (en) * | 2004-12-22 | 2012-06-06 | Cleveland Clinic Foundation | Flagellin related polypeptides and uses thereof |
| EP2374474A1 (en) * | 2005-01-19 | 2011-10-12 | Vaxinnate Corporation | Compositions comprising pathogen-associated molecular patterns and antigens and their use to stimulate an immune response |
| WO2009102818A1 (en) * | 2008-02-11 | 2009-08-20 | Cleveland Biolabs, Inc. | Method for reducing the effects of chemotheraphy using flagellin related polypeptides |
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| CA2777198A1 (en) | 2011-04-14 |
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| CA2777198C (en) | 2018-07-24 |
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| BR112012011331A2 (pt) | 2015-09-15 |
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| EP2486134B1 (en) | 2014-01-08 |
| IL219060A (en) | 2017-02-28 |
| US9205095B2 (en) | 2015-12-08 |
| BR112012011331B8 (pt) | 2021-05-25 |
| BR112012011331B1 (pt) | 2021-03-02 |
| CN104136614B (zh) | 2018-04-06 |
| IL219060A0 (en) | 2012-06-28 |
| EA201290140A1 (ru) | 2012-11-30 |
| US20120208871A1 (en) | 2012-08-16 |
| EA021842B1 (ru) | 2015-09-30 |
| AP2012006253A0 (en) | 2012-06-30 |
| MX2012004095A (es) | 2012-09-12 |
| KR20120104177A (ko) | 2012-09-20 |
| EP2486134A4 (en) | 2013-02-13 |
| AU2010303464B2 (en) | 2014-05-01 |
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