JP5777045B2 - 細胞検出方法及び該方法に用いるマイクロアレイチップ - Google Patents

細胞検出方法及び該方法に用いるマイクロアレイチップ Download PDF

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JP5777045B2
JP5777045B2 JP2010527805A JP2010527805A JP5777045B2 JP 5777045 B2 JP5777045 B2 JP 5777045B2 JP 2010527805 A JP2010527805 A JP 2010527805A JP 2010527805 A JP2010527805 A JP 2010527805A JP 5777045 B2 JP5777045 B2 JP 5777045B2
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cells
microchamber
microarray chip
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JPWO2010027003A1 (ja
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山村　昌平
昌平 山村
聖基 八代
聖基 八代
正俊 片岡
正俊 片岡
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National Institute of Advanced Industrial Science and Technology AIST
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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/02—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving viable microorganisms
    • C12Q1/04—Determining presence or kind of microorganism; Use of selective media for testing antibiotics or bacteriocides; Compositions containing a chemical indicator therefor
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    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
    • G01N33/5091—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing the pathological state of an organism
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/569—Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses
    • G01N33/56905—Protozoa

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  • Wood Science & Technology (AREA)
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  • Proteomics, Peptides & Aminoacids (AREA)
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  • General Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Physiology (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
JP2010527805A 2008-09-02 2009-09-02 細胞検出方法及び該方法に用いるマイクロアレイチップ Active JP5777045B2 (ja)

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JP2008225193 2008-09-02
JP2008225193 2008-09-02
PCT/JP2009/065370 WO2010027003A1 (ja) 2008-09-02 2009-09-02 細胞検出方法及び該方法に用いるマイクロアレイチップ
JP2010527805A JP5777045B2 (ja) 2008-09-02 2009-09-02 細胞検出方法及び該方法に用いるマイクロアレイチップ

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Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2821779A4 (en) 2012-03-29 2015-08-19 Panasonic Ip Man Co Ltd SAMPLE HOLDER, AND FLUORESCENCE DETECTION SYSTEM, AND FLUORESCENCE DETECTION DEVICE USING THE SAME
JP6244556B2 (ja) 2012-04-25 2017-12-13 パナソニックＩｐマネジメント株式会社 試料保持担体およびそれを用いた蛍光検出装置
EP2871232B1 (en) 2012-07-03 2021-05-05 Konica Minolta, Inc. Method for detecting rare cell
EP4148118A1 (en) 2012-08-24 2023-03-15 Yale University System, device and method for high-throughput multi-plexed detection
WO2014061675A1 (ja) * 2012-10-17 2014-04-24 コニカミノルタ株式会社 希少細胞の回収方法および検出方法
EP2916124A4 (en) 2012-10-30 2016-02-17 Panasonic Ip Man Co Ltd SAMPLE CARRIER AND FLUORESCENCE DETECTOR USING SAME
JP6283955B2 (ja) 2012-11-30 2018-02-28 パナソニックＩｐマネジメント株式会社 試料保持担体およびそれを用いた蛍光検出装置
WO2015034011A1 (ja) * 2013-09-04 2015-03-12 独立行政法人産業技術総合研究所 マイクロアレイチップ、及び該チップを用いた細胞解析方法
DE102013020616A1 (de) * 2013-12-15 2015-06-18 Keming Du Bauteile mit Kontaktwinkelverteilungen, deren Herstellung und deren Anwendungen
JP6303496B2 (ja) * 2013-12-26 2018-04-04 コニカミノルタ株式会社 細胞展開用デバイス
JP6465374B2 (ja) * 2014-04-25 2019-02-06 コニカミノルタ株式会社 膜タンパク質評価法
US10584366B2 (en) 2014-12-03 2020-03-10 IsoPlexis Corporation Analysis and screening of cell secretion profiles
US11353448B2 (en) 2015-02-13 2022-06-07 California Institute Of Technology Methods and compositions for quantifying metabolites and proteins from single cells
JPWO2016140327A1 (ja) * 2015-03-04 2017-12-14 国立研究開発法人産業技術総合研究所 マイクロチャンバーアレイプレート
WO2018047707A1 (ja) * 2016-09-06 2018-03-15 学校法人慶應義塾 紫外線吸収剤又は赤外線遮断剤含有水性組成物の紫外線防御効果又は赤外線防御効果の測定方法及び測定用試料作成装置
WO2018049418A1 (en) 2016-09-12 2018-03-15 IsoPlexis Corporation System and methods for multiplexed analysis of cellular and other immunotherapeutics
EP3538891B1 (en) 2016-11-11 2022-01-05 Isoplexis Corporation Compositions and methods for the simultaneous genomic, transcriptomic and proteomic analysis of single cells
US11525783B2 (en) 2016-11-22 2022-12-13 IsoPlexis Corporation Systems, devices and methods for cell capture and methods of manufacture thereof
JP2023173785A (ja) * 2022-05-26 2023-12-07 国立研究開発法人産業技術総合研究所 マイクロアレイチップおよびマイクロアレイチップを用いた細胞培養方法

Citations (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2004144526A (ja) * 2002-10-22 2004-05-20 Japan Science & Technology Agency マラリア感染診断剤及びマラリア原虫染色剤
JP2004187676A (ja) * 2002-11-29 2004-07-08 Atsushi Muraguchi 抗原特異的リンパ球抗原受容体遺伝子のクローニング方法
WO2004086010A1 (ja) * 2003-03-24 2004-10-07 Hitachi Software Engineering Co., Ltd. 吸光度読取装置、吸光度読取装置制御方法及び吸光度算出プログラム
JP2006061023A (ja) * 2004-08-24 2006-03-09 Suntory Ltd マイクロチャンバーアレイを用いたスクリーニング方法およびスクリーニング装置
JP2006101708A (ja) * 2004-09-30 2006-04-20 Sysmex Corp マラリア感染赤血球の測定方法、測定装置、測定用試薬、及びマラリア原虫の測定方法、測定装置、測定用試薬
JP2006181407A (ja) * 2004-12-27 2006-07-13 Pentax Corp Ｐｄｍｓ製シート
JP2008082961A (ja) * 2006-09-28 2008-04-10 Sumitomo Bakelite Co Ltd マイクロ流路デバイス

Family Cites Families (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH08163979A (ja) 1994-10-12 1996-06-25 Sumitomo Bakelite Co Ltd 細胞培養器の包装方法
CA2180082A1 (en) 1995-06-29 1996-12-30 Leslie S. Grushkin-Lerner Culture vessel for use with coverslips
CN1137999C (zh) 2000-07-04 2004-02-11 清华大学 集成式微阵列装置
US6783735B2 (en) * 2000-09-15 2004-08-31 Agfa-Gevaert Web material having wells for combinatorial applications
US7033821B2 (en) * 2000-11-08 2006-04-25 Surface Logix, Inc. Device for monitoring cell motility in real-time
JP2002338306A (ja) 2001-05-14 2002-11-27 Tohpe Corp ガラスの親水化方法、親水化ガラスおよびその製造方法ならびに親水化ガラス製品
ATE349276T1 (de) 2001-06-08 2007-01-15 Centre Nat Rech Scient METHODE ZUR HERSTELLUNG EINER MIKROFLÜSSIGKEITSSTRUKTUR, INSBESONDERE EINES ßBIOCHIPSß, UND DAMIT ERZEUGTE STRUKTUR
US7169577B2 (en) * 2001-07-27 2007-01-30 Surface Logix, Inc. Cell isolation and screening device and method of using same
JP2004125781A (ja) 2002-07-29 2004-04-22 Kanagawa Acad Of Sci & Technol 対細胞作用調査用支持体及びそれを用いた物質の対細胞作用調査方法
AU2003266712A1 (en) * 2002-11-14 2004-06-23 Hiroyuki Kishi Microwell array chip for detecting antigen-specific lymphocyte, method of detecting antigen-specific lymphocyte and method of cloning antigen-specific lymphocyte antigen receptor gene
EP2381255A1 (en) 2003-09-25 2011-10-26 Toyama Prefecture Microwell array chip and its manufacturing method
JP2006055157A (ja) 2004-07-23 2006-03-02 Chisso Corp 細胞培養器具及びその製造方法
KR100839390B1 (ko) * 2004-08-12 2008-06-19 도꾸리쯔 교세이호징 노우교 · 쇼쿠힝 산교 기쥬쯔 소고 겡뀨 기꼬우 마이크로 채널 어레이
CA2599364A1 (en) 2005-03-03 2006-09-08 Iowa State University Research Foundation, Inc. Fluorous-based microarrays
WO2007035633A2 (en) * 2005-09-16 2007-03-29 President & Fellows Of Harvard College Screening assays and methods
JP2008005781A (ja) * 2006-06-29 2008-01-17 Olympus Corp 試料処理方法
JP4425892B2 (ja) * 2006-08-08 2010-03-03 パナソニック株式会社 細胞電気生理センサおよびその製造方法
JP2008139133A (ja) * 2006-12-01 2008-06-19 Matsushita Electric Ind Co Ltd 細胞電気生理センサ

Patent Citations (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2004144526A (ja) * 2002-10-22 2004-05-20 Japan Science & Technology Agency マラリア感染診断剤及びマラリア原虫染色剤
JP2004187676A (ja) * 2002-11-29 2004-07-08 Atsushi Muraguchi 抗原特異的リンパ球抗原受容体遺伝子のクローニング方法
WO2004086010A1 (ja) * 2003-03-24 2004-10-07 Hitachi Software Engineering Co., Ltd. 吸光度読取装置、吸光度読取装置制御方法及び吸光度算出プログラム
JP2006061023A (ja) * 2004-08-24 2006-03-09 Suntory Ltd マイクロチャンバーアレイを用いたスクリーニング方法およびスクリーニング装置
JP2006101708A (ja) * 2004-09-30 2006-04-20 Sysmex Corp マラリア感染赤血球の測定方法、測定装置、測定用試薬、及びマラリア原虫の測定方法、測定装置、測定用試薬
JP2006181407A (ja) * 2004-12-27 2006-07-13 Pentax Corp Ｐｄｍｓ製シート
JP2008082961A (ja) * 2006-09-28 2008-04-10 Sumitomo Bakelite Co Ltd マイクロ流路デバイス

Non-Patent Citations (6)

* Cited by examiner, † Cited by third party
Title
JPN6014015736; 岩波　理化学辞典 第５版, 2003, 第７３９頁 *
JPN6014015740; ＲＥＶＺＩＮ，　Ａ．　ｅｔ　ａｌ．: Ｌａｂ　Ｃｈｉｐ Ｖｏｌ．５, 2005, ｐｐ．３０-３７ *
JPN6014015743; ＲＥＴＴＩＧ，　Ｊ．Ｒ．　ａｎｄ　ＦＯＬＣＨ，　Ａ．: Ａｎａｌ．　Ｃｈｅｍ． Ｖｏｌ．７７, 2005, ｐｐ．５６２８-５６３４ *
JPN6014015745; ＹＡＭＡＭＵＲＡ，　Ｓ．　ｅｔ　ａｌ．: Ａｎａｌ．　Ｃｈｅｍ． Ｖｏｌ．７７, 2005, ｐｐ．８０５０-８０５６ *
JPN6014015749; ＯＳＴＵＮＩ，　Ｅ．　ｅｔ　ａｌ．: Ｌａｎｇｍｕｉｒ Ｖｏｌ．１７, 2001, ｐｐ．２８２８-２８３４ *
JPN6014015751; ＣＡＲＬＯ，　Ｄ．Ｄ．　ａｎｄ　ＬＥＥ，　Ｌ．Ｐ．: Ａｎａｌ．　Ｃｈｅｍ． Ｖｏｌ．７８, 2006, ｐｐ．７９１８-７９２５ *

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WO2010027003A1 (ja) 2010-03-11
US9249445B2 (en) 2016-02-02
EP2336348A4 (en) 2012-01-11
JPWO2010027003A1 (ja) 2012-02-02
JP5995251B2 (ja) 2016-09-21
JP2015083012A (ja) 2015-04-30
US20110189723A1 (en) 2011-08-04
EP2336348B1 (en) 2014-11-05
EP2336348A1 (en) 2011-06-22

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