JP5777045B2 - 細胞検出方法及び該方法に用いるマイクロアレイチップ - Google Patents

細胞検出方法及び該方法に用いるマイクロアレイチップ Download PDF

Info

Publication number
JP5777045B2
JP5777045B2 JP2010527805A JP2010527805A JP5777045B2 JP 5777045 B2 JP5777045 B2 JP 5777045B2 JP 2010527805 A JP2010527805 A JP 2010527805A JP 2010527805 A JP2010527805 A JP 2010527805A JP 5777045 B2 JP5777045 B2 JP 5777045B2
Authority
JP
Japan
Prior art keywords
cells
microchamber
microarray chip
cell
specific
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
JP2010527805A
Other languages
English (en)
Japanese (ja)
Other versions
JPWO2010027003A1 (ja
Inventor
山村 昌平
昌平 山村
聖基 八代
聖基 八代
正俊 片岡
正俊 片岡
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
National Institute of Advanced Industrial Science and Technology AIST
Original Assignee
National Institute of Advanced Industrial Science and Technology AIST
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by National Institute of Advanced Industrial Science and Technology AIST filed Critical National Institute of Advanced Industrial Science and Technology AIST
Priority to JP2010527805A priority Critical patent/JP5777045B2/ja
Publication of JPWO2010027003A1 publication Critical patent/JPWO2010027003A1/ja
Application granted granted Critical
Publication of JP5777045B2 publication Critical patent/JP5777045B2/ja
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Images

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/02Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving viable microorganisms
    • C12Q1/04Determining presence or kind of microorganism; Use of selective media for testing antibiotics or bacteriocides; Compositions containing a chemical indicator therefor
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/5005Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
    • G01N33/5091Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing the pathological state of an organism
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/569Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses
    • G01N33/56905Protozoa

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Physics & Mathematics (AREA)
  • Biotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • Microbiology (AREA)
  • Organic Chemistry (AREA)
  • Biochemistry (AREA)
  • Analytical Chemistry (AREA)
  • Cell Biology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Food Science & Technology (AREA)
  • Zoology (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Wood Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biophysics (AREA)
  • Toxicology (AREA)
  • Virology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Physiology (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
JP2010527805A 2008-09-02 2009-09-02 細胞検出方法及び該方法に用いるマイクロアレイチップ Active JP5777045B2 (ja)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP2010527805A JP5777045B2 (ja) 2008-09-02 2009-09-02 細胞検出方法及び該方法に用いるマイクロアレイチップ

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
JP2008225193 2008-09-02
JP2008225193 2008-09-02
PCT/JP2009/065370 WO2010027003A1 (ja) 2008-09-02 2009-09-02 細胞検出方法及び該方法に用いるマイクロアレイチップ
JP2010527805A JP5777045B2 (ja) 2008-09-02 2009-09-02 細胞検出方法及び該方法に用いるマイクロアレイチップ

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2014260136A Division JP5995251B2 (ja) 2008-09-02 2014-12-24 細胞検出方法及び該方法に用いるマイクロアレイチップ

Publications (2)

Publication Number Publication Date
JPWO2010027003A1 JPWO2010027003A1 (ja) 2012-02-02
JP5777045B2 true JP5777045B2 (ja) 2015-09-09

Family

ID=41797169

Family Applications (2)

Application Number Title Priority Date Filing Date
JP2010527805A Active JP5777045B2 (ja) 2008-09-02 2009-09-02 細胞検出方法及び該方法に用いるマイクロアレイチップ
JP2014260136A Active JP5995251B2 (ja) 2008-09-02 2014-12-24 細胞検出方法及び該方法に用いるマイクロアレイチップ

Family Applications After (1)

Application Number Title Priority Date Filing Date
JP2014260136A Active JP5995251B2 (ja) 2008-09-02 2014-12-24 細胞検出方法及び該方法に用いるマイクロアレイチップ

Country Status (4)

Country Link
US (1) US9249445B2 (https=)
EP (1) EP2336348B1 (https=)
JP (2) JP5777045B2 (https=)
WO (1) WO2010027003A1 (https=)

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2013146364A1 (ja) 2012-03-29 2013-10-03 三洋電機株式会社 試料保持担体およびそれを用いた蛍光検出システム、蛍光検出装置
JP6244556B2 (ja) 2012-04-25 2017-12-13 パナソニックIpマネジメント株式会社 試料保持担体およびそれを用いた蛍光検出装置
JP6218185B2 (ja) 2012-07-03 2017-10-25 コニカミノルタ株式会社 細胞展開用デバイスおよび希少細胞の検出方法
CN108267581A (zh) 2012-08-24 2018-07-10 耶鲁大学 用于高通量多重检测的系统、装置和方法
US10866169B2 (en) * 2012-10-17 2020-12-15 Konica Minolta, Inc. Method for recovering rare cells and method for detecting rare cells
WO2014068951A1 (ja) 2012-10-30 2014-05-08 パナソニック株式会社 試料保持担体およびそれを用いた蛍光検出装置
JP6283955B2 (ja) 2012-11-30 2018-02-28 パナソニックIpマネジメント株式会社 試料保持担体およびそれを用いた蛍光検出装置
WO2015034011A1 (ja) * 2013-09-04 2015-03-12 独立行政法人産業技術総合研究所 マイクロアレイチップ、及び該チップを用いた細胞解析方法
DE102013020616A1 (de) * 2013-12-15 2015-06-18 Keming Du Bauteile mit Kontaktwinkelverteilungen, deren Herstellung und deren Anwendungen
JP6303496B2 (ja) * 2013-12-26 2018-04-04 コニカミノルタ株式会社 細胞展開用デバイス
JP6465374B2 (ja) * 2014-04-25 2019-02-06 コニカミノルタ株式会社 膜タンパク質評価法
CN112782140A (zh) 2014-12-03 2021-05-11 伊索普莱西斯公司 细胞分泌特征的分析和筛选
US11353448B2 (en) 2015-02-13 2022-06-07 California Institute Of Technology Methods and compositions for quantifying metabolites and proteins from single cells
WO2016140327A1 (ja) * 2015-03-04 2016-09-09 国立研究開発法人産業技術総合研究所 マイクロチャンバーアレイプレート
US11525779B2 (en) * 2016-09-06 2022-12-13 Keio University Method and device for measuring absorbance of aqueous compositions using a substrate having a surface with an adjusted contact angle with water
EP3510398B1 (en) 2016-09-12 2026-02-25 Isoplexis Corporation System and methods for multiplexed analysis of cellular and other immunotherapeutics
EP4036578A1 (en) 2016-11-11 2022-08-03 Isoplexis Corporation Compositions and methods for the simultaneous genomic, transcriptomic and proteomic analysis of single cells
CN110226084A (zh) 2016-11-22 2019-09-10 伊索普莱克西斯公司 用于细胞捕获的系统、装置和方法,以及其制造方法
JP2023173785A (ja) * 2022-05-26 2023-12-07 国立研究開発法人産業技術総合研究所 マイクロアレイチップおよびマイクロアレイチップを用いた細胞培養方法

Citations (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2004144526A (ja) * 2002-10-22 2004-05-20 Japan Science & Technology Agency マラリア感染診断剤及びマラリア原虫染色剤
JP2004187676A (ja) * 2002-11-29 2004-07-08 Atsushi Muraguchi 抗原特異的リンパ球抗原受容体遺伝子のクローニング方法
WO2004086010A1 (ja) * 2003-03-24 2004-10-07 Hitachi Software Engineering Co., Ltd. 吸光度読取装置、吸光度読取装置制御方法及び吸光度算出プログラム
JP2006061023A (ja) * 2004-08-24 2006-03-09 Suntory Ltd マイクロチャンバーアレイを用いたスクリーニング方法およびスクリーニング装置
JP2006101708A (ja) * 2004-09-30 2006-04-20 Sysmex Corp マラリア感染赤血球の測定方法、測定装置、測定用試薬、及びマラリア原虫の測定方法、測定装置、測定用試薬
JP2006181407A (ja) * 2004-12-27 2006-07-13 Pentax Corp Pdms製シート
JP2008082961A (ja) * 2006-09-28 2008-04-10 Sumitomo Bakelite Co Ltd マイクロ流路デバイス

Family Cites Families (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH08163979A (ja) 1994-10-12 1996-06-25 Sumitomo Bakelite Co Ltd 細胞培養器の包装方法
EP0751215A3 (en) 1995-06-29 1997-03-05 Becton Dickinson Co Culture container for use with culture plates
CN1137999C (zh) 2000-07-04 2004-02-11 清华大学 集成式微阵列装置
US6783735B2 (en) 2000-09-15 2004-08-31 Agfa-Gevaert Web material having wells for combinatorial applications
US7033821B2 (en) * 2000-11-08 2006-04-25 Surface Logix, Inc. Device for monitoring cell motility in real-time
JP2002338306A (ja) 2001-05-14 2002-11-27 Tohpe Corp ガラスの親水化方法、親水化ガラスおよびその製造方法ならびに親水化ガラス製品
ATE349276T1 (de) 2001-06-08 2007-01-15 Centre Nat Rech Scient METHODE ZUR HERSTELLUNG EINER MIKROFLÜSSIGKEITSSTRUKTUR, INSBESONDERE EINES ßBIOCHIPSß, UND DAMIT ERZEUGTE STRUKTUR
US7169577B2 (en) * 2001-07-27 2007-01-30 Surface Logix, Inc. Cell isolation and screening device and method of using same
JP2004125781A (ja) 2002-07-29 2004-04-22 Kanagawa Acad Of Sci & Technol 対細胞作用調査用支持体及びそれを用いた物質の対細胞作用調査方法
DK1566635T3 (da) 2002-11-14 2012-03-19 Vivalis Chip med array af mikrobrønde til påvisning af antigenspecifik lymfocyt, fremgangsmåde til påvisning af antigenspecifik lymfocyt og fremgangsmåde til kloning af antigenspecifik lymfocyt-antigenreceptorgen
JP4069171B2 (ja) 2003-09-25 2008-04-02 富山県 マイクロウェルアレイチップ及びその製造方法
JP2006055157A (ja) 2004-07-23 2006-03-02 Chisso Corp 細胞培養器具及びその製造方法
AU2005272546B2 (en) 2004-08-12 2010-11-11 Yuji Kikuchi Micro channel array
CA2599364A1 (en) 2005-03-03 2006-09-08 Iowa State University Research Foundation, Inc. Fluorous-based microarrays
WO2007035633A2 (en) * 2005-09-16 2007-03-29 President & Fellows Of Harvard College Screening assays and methods
JP2008005781A (ja) * 2006-06-29 2008-01-17 Olympus Corp 試料処理方法
JP4425892B2 (ja) * 2006-08-08 2010-03-03 パナソニック株式会社 細胞電気生理センサおよびその製造方法
JP2008139133A (ja) * 2006-12-01 2008-06-19 Matsushita Electric Ind Co Ltd 細胞電気生理センサ

Patent Citations (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2004144526A (ja) * 2002-10-22 2004-05-20 Japan Science & Technology Agency マラリア感染診断剤及びマラリア原虫染色剤
JP2004187676A (ja) * 2002-11-29 2004-07-08 Atsushi Muraguchi 抗原特異的リンパ球抗原受容体遺伝子のクローニング方法
WO2004086010A1 (ja) * 2003-03-24 2004-10-07 Hitachi Software Engineering Co., Ltd. 吸光度読取装置、吸光度読取装置制御方法及び吸光度算出プログラム
JP2006061023A (ja) * 2004-08-24 2006-03-09 Suntory Ltd マイクロチャンバーアレイを用いたスクリーニング方法およびスクリーニング装置
JP2006101708A (ja) * 2004-09-30 2006-04-20 Sysmex Corp マラリア感染赤血球の測定方法、測定装置、測定用試薬、及びマラリア原虫の測定方法、測定装置、測定用試薬
JP2006181407A (ja) * 2004-12-27 2006-07-13 Pentax Corp Pdms製シート
JP2008082961A (ja) * 2006-09-28 2008-04-10 Sumitomo Bakelite Co Ltd マイクロ流路デバイス

Non-Patent Citations (6)

* Cited by examiner, † Cited by third party
Title
JPN6014015736; 岩波 理化学辞典 第5版, 2003, 第739頁 *
JPN6014015740; REVZIN, A. et al.: Lab Chip Vol.5, 2005, pp.30-37 *
JPN6014015743; RETTIG, J.R. and FOLCH, A.: Anal. Chem. Vol.77, 2005, pp.5628-5634 *
JPN6014015745; YAMAMURA, S. et al.: Anal. Chem. Vol.77, 2005, pp.8050-8056 *
JPN6014015749; OSTUNI, E. et al.: Langmuir Vol.17, 2001, pp.2828-2834 *
JPN6014015751; CARLO, D.D. and LEE, L.P.: Anal. Chem. Vol.78, 2006, pp.7918-7925 *

Also Published As

Publication number Publication date
JP5995251B2 (ja) 2016-09-21
JPWO2010027003A1 (ja) 2012-02-02
EP2336348A4 (en) 2012-01-11
JP2015083012A (ja) 2015-04-30
EP2336348A1 (en) 2011-06-22
US20110189723A1 (en) 2011-08-04
WO2010027003A1 (ja) 2010-03-11
EP2336348B1 (en) 2014-11-05
US9249445B2 (en) 2016-02-02

Similar Documents

Publication Publication Date Title
JP5995251B2 (ja) 細胞検出方法及び該方法に用いるマイクロアレイチップ
US12442029B2 (en) Method and system for imaging a blood sample
KR101087809B1 (ko) 단일 세포 및 콜로니의 수집을 위한 시스템
EP2356249B1 (en) Genetic analysis in microwells
TW201104253A (en) Microarray chip and method of fabricating for the same
CN102460171A (zh) 细胞群和混合细胞群变化的检测
JP2005506083A (ja) 相互作用型透明個別細胞バイオチッププロセッサー
Zhang et al. Microfluidic flow cytometry for blood-based biomarker analysis
JP5289064B2 (ja) 生物学的サンプルの画像化および修飾のための装置および方法
WO2016112344A1 (en) Position-defined cell culture and characterization platform
JPWO2016140327A1 (ja) マイクロチャンバーアレイプレート
JP6395712B2 (ja) マイクロアレイチップ、及び該チップを用いた細胞解析方法
Schiffenbauer et al. A cell chip for sequential imaging of individual non-adherent live cells reveals transients and oscillations
WO2007138568A2 (en) A device for microscopy flow-through experiments on non-adherent live cells
JP4336812B2 (ja) 細胞に発現する表面抗原を迅速に同定するための分析方法
WO2010040804A2 (en) Methods for controlled seeding of adherent cell types on high density patterned cell cultures
JP2018134026A (ja) 細胞保持方法

Legal Events

Date Code Title Description
A621 Written request for application examination

Free format text: JAPANESE INTERMEDIATE CODE: A621

Effective date: 20111116

A131 Notification of reasons for refusal

Free format text: JAPANESE INTERMEDIATE CODE: A131

Effective date: 20130716

A521 Request for written amendment filed

Free format text: JAPANESE INTERMEDIATE CODE: A523

Effective date: 20130906

A131 Notification of reasons for refusal

Free format text: JAPANESE INTERMEDIATE CODE: A131

Effective date: 20140415

A521 Request for written amendment filed

Free format text: JAPANESE INTERMEDIATE CODE: A523

Effective date: 20140610

A521 Request for written amendment filed

Free format text: JAPANESE INTERMEDIATE CODE: A821

Effective date: 20140610

A02 Decision of refusal

Free format text: JAPANESE INTERMEDIATE CODE: A02

Effective date: 20140924

A521 Request for written amendment filed

Free format text: JAPANESE INTERMEDIATE CODE: A523

Effective date: 20141224

A911 Transfer to examiner for re-examination before appeal (zenchi)

Free format text: JAPANESE INTERMEDIATE CODE: A911

Effective date: 20150218

A912 Re-examination (zenchi) completed and case transferred to appeal board

Free format text: JAPANESE INTERMEDIATE CODE: A912

Effective date: 20150306

A521 Request for written amendment filed

Free format text: JAPANESE INTERMEDIATE CODE: A821

Effective date: 20150320

A521 Request for written amendment filed

Free format text: JAPANESE INTERMEDIATE CODE: A523

Effective date: 20150529

A61 First payment of annual fees (during grant procedure)

Free format text: JAPANESE INTERMEDIATE CODE: A61

Effective date: 20150630

R150 Certificate of patent or registration of utility model

Ref document number: 5777045

Country of ref document: JP

Free format text: JAPANESE INTERMEDIATE CODE: R150

R250 Receipt of annual fees

Free format text: JAPANESE INTERMEDIATE CODE: R250

R250 Receipt of annual fees

Free format text: JAPANESE INTERMEDIATE CODE: R250

R250 Receipt of annual fees

Free format text: JAPANESE INTERMEDIATE CODE: R250

R250 Receipt of annual fees

Free format text: JAPANESE INTERMEDIATE CODE: R250

R250 Receipt of annual fees

Free format text: JAPANESE INTERMEDIATE CODE: R250

R250 Receipt of annual fees

Free format text: JAPANESE INTERMEDIATE CODE: R250

R250 Receipt of annual fees

Free format text: JAPANESE INTERMEDIATE CODE: R250

R250 Receipt of annual fees

Free format text: JAPANESE INTERMEDIATE CODE: R250