JP5756105B2 - パーキンソン病の治療のための組成物および方法 - Google Patents

パーキンソン病の治療のための組成物および方法 Download PDF

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JP5756105B2
JP5756105B2 JP2012521920A JP2012521920A JP5756105B2 JP 5756105 B2 JP5756105 B2 JP 5756105B2 JP 2012521920 A JP2012521920 A JP 2012521920A JP 2012521920 A JP2012521920 A JP 2012521920A JP 5756105 B2 JP5756105 B2 JP 5756105B2
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parkinson
days
disease
haloperidol
dopamine
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Japanese (ja)
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JP2013500943A (ja
JP2013500943A5 (enExample
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フィリップ シーマン
フィリップ シーマン
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クレラ インコーポレイティッド
クレラ インコーポレイティッド
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445Non condensed piperidines, e.g. piperocaine
    • A61K31/4515Non condensed piperidines, e.g. piperocaine having a butyrophenone group in position 1, e.g. haloperidol
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0053Mouth and digestive tract, i.e. intraoral and peroral administration
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/14Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A61P25/16Anti-Parkinson drugs
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/28Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2121/00Preparations for use in therapy

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  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Neurosurgery (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Hospice & Palliative Care (AREA)
  • Psychology (AREA)
  • Psychiatry (AREA)
  • Nutrition Science (AREA)
  • Physiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
JP2012521920A 2009-07-31 2010-07-30 パーキンソン病の治療のための組成物および方法 Expired - Fee Related JP5756105B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US23026409P 2009-07-31 2009-07-31
US61/230,264 2009-07-31
PCT/CA2010/001185 WO2011011886A1 (en) 2009-07-31 2010-07-30 Compositions and methods for treating parkinson's disease

Publications (3)

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JP2013500943A JP2013500943A (ja) 2013-01-10
JP2013500943A5 JP2013500943A5 (enExample) 2013-09-19
JP5756105B2 true JP5756105B2 (ja) 2015-07-29

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ID=43528672

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JP2012521920A Expired - Fee Related JP5756105B2 (ja) 2009-07-31 2010-07-30 パーキンソン病の治療のための組成物および方法

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Country Link
US (1) US9192605B2 (enExample)
EP (1) EP2459194A4 (enExample)
JP (1) JP5756105B2 (enExample)
KR (1) KR20120103557A (enExample)
CN (1) CN102548555A (enExample)
AU (1) AU2010278645A1 (enExample)
BR (1) BR112012008193A2 (enExample)
CA (1) CA2769149A1 (enExample)
IL (1) IL217149A0 (enExample)
MX (1) MX2012001290A (enExample)
NZ (1) NZ598247A (enExample)
WO (1) WO2011011886A1 (enExample)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA3178035A1 (en) 2012-12-24 2014-07-03 Neurogastrx, Inc. Methods for treating gi tract disorders
JP6371716B2 (ja) * 2014-04-01 2018-08-08 東京エレクトロン株式会社 基板液処理装置及び基板液処理方法並びに基板液処理プログラムを記録したコンピュータ読み取り可能な記録媒体
WO2015200369A1 (en) 2014-06-24 2015-12-30 Neurogastrx, Inc. Prodrugs of metopimazine
US10836757B1 (en) 2020-04-02 2020-11-17 Neurogastrx, Inc. Polymorphic forms of metopimazine
CN114601928B (zh) * 2022-04-02 2023-03-17 首都医科大学 一种钙超载介导神经元死亡的标志物及应用

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1219667B (it) * 1988-06-21 1990-05-24 Polifarma Spa Impiego di uridina nel trattamento farmacologico di disturbi dovuti ad alterato equilibrio dopaminergico
RU2057529C1 (ru) * 1994-05-30 1996-04-10 Алексей Михайлович Коршунов Способ лечения синдрома паркинсонизма
US20010056101A1 (en) * 1998-06-29 2001-12-27 Carol A. Tamminga Use of dopamine receptor antagonists in combination with partial dopamine agonist to prevent tolerance in treating nervous disorders related to dopamine dysfunction
DE10111486A1 (de) * 2001-03-09 2002-10-02 Ralph R Dawirs Verwendung einer oder mehrerer neuroaktiver Substanzen zur Behandlung der Parkinsonschen Krankheit
ES2286453T3 (es) * 2002-09-17 2007-12-01 Motac Neuroscience Limited Tratamiento de la discinesia.
CN1802153A (zh) * 2002-10-22 2006-07-12 药物滥用科学研究公司 用选择性多巴胺d1受体激动剂治疗认知损害
CA2628298A1 (en) * 2004-11-03 2006-05-11 Clera Inc. Method to detect dopamine receptors in the functional d2high state
AU2009212065B2 (en) * 2008-02-05 2014-03-20 Clera Inc. Compositions and methods for alleviating depression or improving cognition

Also Published As

Publication number Publication date
CA2769149A1 (en) 2011-02-03
US9192605B2 (en) 2015-11-24
EP2459194A4 (en) 2012-12-19
JP2013500943A (ja) 2013-01-10
IL217149A0 (en) 2012-02-29
AU2010278645A1 (en) 2012-03-08
CN102548555A (zh) 2012-07-04
US20120115910A1 (en) 2012-05-10
BR112012008193A2 (pt) 2016-03-01
NZ598247A (en) 2014-01-31
MX2012001290A (es) 2012-06-12
WO2011011886A1 (en) 2011-02-03
EP2459194A1 (en) 2012-06-06
KR20120103557A (ko) 2012-09-19

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