JP5752035B2 - 疎水性ポリマーに由来する親水性相互貫入ポリマーネットワーク - Google Patents

疎水性ポリマーに由来する親水性相互貫入ポリマーネットワーク Download PDF

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JP5752035B2
JP5752035B2 JP2011517526A JP2011517526A JP5752035B2 JP 5752035 B2 JP5752035 B2 JP 5752035B2 JP 2011517526 A JP2011517526 A JP 2011517526A JP 2011517526 A JP2011517526 A JP 2011517526A JP 5752035 B2 JP5752035 B2 JP 5752035B2
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semi
polymer
polyurethane
acrylic acid
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JP2011527377A5 (enExample
JP2011527377A (ja
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ディヴィッド ミュン
ディヴィッド ミュン
マイケル ジェイ ジャースマ
マイケル ジェイ ジャースマ
ランプロス クルティス
ランプロス クルティス
カート フランク
カート フランク
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バイオミメディカ インコーポレイテッド
バイオミメディカ インコーポレイテッド
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    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08F—MACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
    • C08F283/00—Macromolecular compounds obtained by polymerising monomers on to polymers provided for in subclass C08G
    • C08F283/06—Macromolecular compounds obtained by polymerising monomers on to polymers provided for in subclass C08G on to polyethers, polyoxymethylenes or polyacetals
    • C08F283/065—Macromolecular compounds obtained by polymerising monomers on to polymers provided for in subclass C08G on to polyethers, polyoxymethylenes or polyacetals on to unsaturated polyethers, polyoxymethylenes or polyacetals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02—Prostheses implantable into the body
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02—Prostheses implantable into the body
    • A61F2/28—Bones
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02—Prostheses implantable into the body
    • A61F2/30—Joints
    • A61F2/30756—Cartilage endoprostheses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/14—Macromolecular materials
    • A61L27/26—Mixtures of macromolecular compounds
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08F—MACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
    • C08F220/00—Copolymers of compounds having one or more unsaturated aliphatic radicals, each having only one carbon-to-carbon double bond, and only one being terminated by only one carboxyl radical or a salt, anhydride ester, amide, imide or nitrile thereof
    • C08F220/02—Monocarboxylic acids having less than ten carbon atoms; Derivatives thereof
    • C08F220/04—Acids; Metal salts or ammonium salts thereof
    • C08F220/06—Acrylic acid; Methacrylic acid; Metal salts or ammonium salts thereof
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08F—MACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
    • C08F222/00—Copolymers of compounds having one or more unsaturated aliphatic radicals, each having only one carbon-to-carbon double bond, and at least one being terminated by a carboxyl radical and containing at least one other carboxyl radical in the molecule; Salts, anhydrides, esters, amides, imides, or nitriles thereof
    • C08F222/10—Esters
    • C08F222/1006—Esters of polyhydric alcohols or polyhydric phenols
    • C08F222/102—Esters of polyhydric alcohols or polyhydric phenols of dialcohols, e.g. ethylene glycol di(meth)acrylate or 1,4-butanediol dimethacrylate
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08F—MACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
    • C08F283/00—Macromolecular compounds obtained by polymerising monomers on to polymers provided for in subclass C08G
    • C08F283/006—Macromolecular compounds obtained by polymerising monomers on to polymers provided for in subclass C08G on to polymers provided for in C08G18/00
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08F—MACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
    • C08F283/00—Macromolecular compounds obtained by polymerising monomers on to polymers provided for in subclass C08G
    • C08F283/02—Macromolecular compounds obtained by polymerising monomers on to polymers provided for in subclass C08G on to polycarbonates or saturated polyesters
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08F—MACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
    • C08F283/00—Macromolecular compounds obtained by polymerising monomers on to polymers provided for in subclass C08G
    • C08F283/06—Macromolecular compounds obtained by polymerising monomers on to polymers provided for in subclass C08G on to polyethers, polyoxymethylenes or polyacetals
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08F—MACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
    • C08F297/00—Macromolecular compounds obtained by successively polymerising different monomer systems using a catalyst of the ionic or coordination type without deactivating the intermediate polymer
    • C08F297/02—Macromolecular compounds obtained by successively polymerising different monomer systems using a catalyst of the ionic or coordination type without deactivating the intermediate polymer using a catalyst of the anionic type
    • C08F297/04—Macromolecular compounds obtained by successively polymerising different monomer systems using a catalyst of the ionic or coordination type without deactivating the intermediate polymer using a catalyst of the anionic type polymerising vinyl aromatic monomers and conjugated dienes
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
    • C08G18/00—Polymeric products of isocyanates or isothiocyanates
    • C08G18/06—Polymeric products of isocyanates or isothiocyanates with compounds having active hydrogen
    • C08G18/83—Chemically modified polymers
    • C08G18/831—Chemically modified polymers by oxygen-containing compounds inclusive of carbonic acid halogenides, carboxylic acid halogenides and epoxy halides
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08L—COMPOSITIONS OF MACROMOLECULAR COMPOUNDS
    • C08L75/00—Compositions of polyureas or polyurethanes; Compositions of derivatives of such polymers
    • C08L75/04—Polyurethanes
    • C08L75/06—Polyurethanes from polyesters
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08L—COMPOSITIONS OF MACROMOLECULAR COMPOUNDS
    • C08L75/00—Compositions of polyureas or polyurethanes; Compositions of derivatives of such polymers
    • C08L75/04—Polyurethanes
    • C08L75/14—Polyurethanes having carbon-to-carbon unsaturated bonds
    • C08L75/16—Polyurethanes having carbon-to-carbon unsaturated bonds having terminal carbon-to-carbon unsaturated bonds
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
    • C08G2270/00—Compositions for creating interpenetrating networks
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08L—COMPOSITIONS OF MACROMOLECULAR COMPOUNDS
    • C08L2205/00—Polymer mixtures characterised by other features
    • C08L2205/04—Polymer mixtures characterised by other features containing interpenetrating networks
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08L—COMPOSITIONS OF MACROMOLECULAR COMPOUNDS
    • C08L33/00—Compositions of homopolymers or copolymers of compounds having one or more unsaturated aliphatic radicals, each having only one carbon-to-carbon double bond, and only one being terminated by only one carboxyl radical, or of salts, anhydrides, esters, amides, imides or nitriles thereof; Compositions of derivatives of such polymers
    • C08L33/02—Homopolymers or copolymers of acids; Metal or ammonium salts thereof
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08L—COMPOSITIONS OF MACROMOLECULAR COMPOUNDS
    • C08L75/00—Compositions of polyureas or polyurethanes; Compositions of derivatives of such polymers
    • C08L75/04—Polyurethanes

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  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Polymers & Plastics (AREA)
  • Transplantation (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Vascular Medicine (AREA)
  • Biomedical Technology (AREA)
  • Engineering & Computer Science (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • General Chemical & Material Sciences (AREA)
  • Inorganic Chemistry (AREA)
  • Dermatology (AREA)
  • Rheumatology (AREA)
  • Epidemiology (AREA)
  • Materials For Medical Uses (AREA)
  • Compositions Of Macromolecular Compounds (AREA)
  • Prostheses (AREA)
  • Processes Of Treating Macromolecular Substances (AREA)
  • Polymerisation Methods In General (AREA)
  • Graft Or Block Polymers (AREA)
JP2011517526A 2008-07-07 2009-07-07 疎水性ポリマーに由来する親水性相互貫入ポリマーネットワーク Active JP5752035B2 (ja)

Applications Claiming Priority (9)

Application Number Priority Date Filing Date Title
US7874108P 2008-07-07 2008-07-07
US61/078,741 2008-07-07
US7906008P 2008-07-08 2008-07-08
US61/079,060 2008-07-08
US9527308P 2008-09-08 2008-09-08
US61/095,273 2008-09-08
US16619409P 2009-04-02 2009-04-02
US61/166,194 2009-04-02
PCT/US2009/049846 WO2010005992A1 (en) 2008-07-07 2009-07-07 Hydrophilic interpenetrating polymer networks derived from hydrophobic polymers

Publications (3)

Publication Number Publication Date
JP2011527377A JP2011527377A (ja) 2011-10-27
JP2011527377A5 JP2011527377A5 (enExample) 2012-08-30
JP5752035B2 true JP5752035B2 (ja) 2015-07-22

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Country Status (7)

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US (5) US20100010114A1 (enExample)
EP (1) EP2297217B1 (enExample)
JP (1) JP5752035B2 (enExample)
KR (1) KR20110044219A (enExample)
AU (1) AU2009268687A1 (enExample)
CA (1) CA2727777A1 (enExample)
WO (1) WO2010005992A1 (enExample)

Families Citing this family (63)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20090088846A1 (en) * 2007-04-17 2009-04-02 David Myung Hydrogel arthroplasty device
KR20110044219A (ko) * 2008-07-07 2011-04-28 바이오미메디카, 인코포레이티드 소수성 중합체에서 유래된 친수성 상호 침투 중합체 네트워크
US20120209396A1 (en) 2008-07-07 2012-08-16 David Myung Orthopedic implants having gradient polymer alloys
US9808345B2 (en) 2008-07-24 2017-11-07 Iorthopedics, Inc. Resilient arthroplasty device
KR20110040969A (ko) 2008-08-05 2011-04-20 바이오미메디카, 인코포레이티드 폴리우레탄-그라프트된 하이드로겔
US10258473B2 (en) * 2008-11-19 2019-04-16 Softjoint Corporation Device and method for restoring joints with artificial cartilage
US20110152868A1 (en) * 2009-12-18 2011-06-23 Lampros Kourtis Method, device, and system for shaving and shaping of a joint
CN102834073B (zh) 2010-01-22 2016-01-13 R·托马斯·哥罗兹 弹性膝盖植入物及方法
US10307257B2 (en) 2010-01-22 2019-06-04 Iorthopedics, Inc. Resilient knee implant and methods
CA2789784A1 (en) * 2010-02-23 2011-09-01 University Of Connecticut Natural polymer-based orthopedic fixation screw for bone repair and regeneration
WO2011163070A1 (en) * 2010-06-25 2011-12-29 3M Innovative Properties Company Semi-interpenetrating polymer network
WO2012027678A1 (en) 2010-08-27 2012-03-01 Biomimedica, Inc. Hydrophobic and hydrophilic interpenetrating polymer networks derived from hydrophobic polymers and methods of preparing the same
US20120109328A1 (en) * 2010-10-29 2012-05-03 Biomet Manufacturing Corp. Acetabular Labrum Implant
JP2014506177A (ja) * 2011-01-10 2014-03-13 バイオミメディカ インコーポレイテッド 勾配ポリマーアロイを有する整形外科用インプラント
USD833613S1 (en) 2011-01-19 2018-11-13 Iorthopedics, Inc. Resilient knee implant
US9023112B2 (en) * 2011-02-24 2015-05-05 Depuy (Ireland) Maintaining proper mechanics THA
GB201106016D0 (en) * 2011-04-08 2011-05-25 Heales Entpr Ltd Polymers
EP2750629B1 (en) 2011-09-01 2016-07-13 R. Thomas Grotz Resilient interpositional arthroplasty device
US20130103157A1 (en) 2011-10-03 2013-04-25 Lampros Kourtis Polymeric adhesive for anchoring compliant materials to another surface
EP3335673B1 (en) * 2011-11-21 2025-07-30 Hyalex Orthopaedics, Inc. Systems for anchoring orthopaedic implants to bone
US20190218386A1 (en) * 2012-01-10 2019-07-18 Hyalex Orthopaedics, Inc. Ionic polymer compositions
KR20140123405A (ko) * 2012-01-12 2014-10-22 세키스이가가쿠 고교가부시키가이샤 수지 복합 재료 및 수지 복합 재료의 제조 방법
US20130211529A1 (en) * 2012-02-10 2013-08-15 Softjoint Corporation Joint augmentation implant and applications thereof
JP5919987B2 (ja) * 2012-04-13 2016-05-18 ユーエムジー・エービーエス株式会社 潤滑性熱可塑性樹脂組成物およびその成形品
US8952105B2 (en) * 2012-05-23 2015-02-10 Baker Hughes Incorporated Variable TG article, method of making, and use of same
CA2883907A1 (en) * 2012-09-11 2014-03-20 Mirteq Pty Limited Vinyl functional interpenetrating network polymers produced by physically mixing vinyl functional resins with thermoplastic resins compositions, methods of use and methods of preparation
WO2014055480A1 (en) 2012-10-02 2014-04-10 Mccullen Seth Implantable devices for musculoskeletal repair and regeneration
US20150282934A1 (en) * 2012-10-11 2015-10-08 Poly-Med, Inc. Multilayer polymeric compositions and methods relating thereto
ES2466065B1 (es) * 2012-12-07 2015-03-31 Universidade De Santiago De Compostela Modificación de poliuretano con polímeros sensibles a estímulos biocompatibles para carga y cesión de fármacos
US9345577B2 (en) 2013-03-14 2016-05-24 Microaire Surgical Instruments Llc Balloon implant device
DE102013016899A1 (de) * 2013-10-11 2015-05-21 Josef Jansen Gelenkspacer
WO2015151949A1 (ja) * 2014-04-02 2015-10-08 東亞合成株式会社 高強度エラストマー
WO2015157356A1 (en) * 2014-04-08 2015-10-15 Carl Deirmengian Orthopedic implant and complementary encasement for supplying a payload of beneficial agent to the implant
US20170072088A1 (en) * 2014-05-05 2017-03-16 Lubrizol Advanced Materials, Inc. Homogenous film compositions
US10034755B2 (en) 2014-10-02 2018-07-31 Seth McCullen Anatomically designed meniscus implantable devices
US10617794B2 (en) 2015-02-23 2020-04-14 Trustees Of Boston University Macroinitiators for hydrophilic coatings on latex and applications thereof
US12053384B2 (en) 2015-02-27 2024-08-06 Idr-Biomed Ltd Buffer for femoral head and neck excision
GB2535767A (en) * 2015-02-27 2016-08-31 Idr-Biomed Ltd Buffer for femoral head and neck excision
US10213284B2 (en) 2015-06-30 2019-02-26 Tela Bio, Inc. Corner-lock stitch patterns
EP3324882B1 (en) 2015-07-21 2023-10-25 Tela Bio, Inc. Compliance control stitching in substrate materials
WO2017027590A1 (en) 2015-08-10 2017-02-16 Hyale Surgical, Inc. Interpenetrating polymer networks
US11077228B2 (en) 2015-08-10 2021-08-03 Hyalex Orthopaedics, Inc. Interpenetrating polymer networks
KR101742240B1 (ko) 2015-08-31 2017-06-01 숭실대학교산학협력단 커패시터형 촉각센서 및 그 제조방법
US10626272B2 (en) 2015-11-11 2020-04-21 Dic Corporation Method for producing semi-IPN composite and method for producing moisture-permeable film
JP6112284B1 (ja) * 2015-11-11 2017-04-12 Dic株式会社 セミｉｐｎ型複合体の製造方法、及び、透湿フィルムの製造方法
JP6112285B1 (ja) * 2015-11-11 2017-04-12 Dic株式会社 セミｉｐｎ型複合体の製造方法、及び、合成皮革の製造方法
WO2017082010A1 (ja) * 2015-11-11 2017-05-18 Dic株式会社 セミｉｐｎ型複合体の製造方法、及び、合成皮革の製造方法
EP3448308B1 (en) 2016-04-26 2024-08-14 Tela Bio, Inc. Hernia repair grafts having anti-adhesion barriers
CN110709110B (zh) * 2017-04-05 2023-05-16 赛特博恩医疗有限公司 性质改变的植入物
WO2018204440A2 (en) 2017-05-02 2018-11-08 Mccullen Seth Composite joint implant
ES3044257T3 (en) * 2017-11-16 2025-11-26 Mativ Luxembourg Thermoplastic polymer film with interpenetrating polymer network
CN111587121B (zh) * 2017-12-29 2024-02-20 Bef医疗公司 用于再生人纤维软骨或弹性软骨的组合物
US11590262B2 (en) 2018-03-09 2023-02-28 Tela Bio, Inc. Surgical repair graft
CZ308284B6 (cs) * 2018-03-15 2020-04-15 Ústav makromolekulární chemie AV ČR, v. v. i. Přípravek na bázi interpenetrujících polymerních sítí pro hojení ran
US10869950B2 (en) 2018-07-17 2020-12-22 Hyalex Orthopaedics, Inc. Ionic polymer compositions
AU2019307605B2 (en) 2018-07-17 2024-08-22 Hyalex Orthopaedics, Inc. Ionic polymer compositions
WO2020185688A1 (en) 2019-03-08 2020-09-17 Tela Bio, Inc. Textured medical textiles
CN110170076A (zh) * 2019-03-18 2019-08-27 苏州恒瑞宏远医疗科技有限公司 头端可洗脱微导管
NL1043315B1 (en) * 2019-06-27 2021-02-01 Jointsphere B V Plug-shaped implant for the replacement and regeneration of biological tissue and method for preparing the implant
WO2021222612A1 (en) * 2020-04-29 2021-11-04 The Board Of Trustees Of The Leland Stanford Junior University Hydrogels for in situ-forming tissue constructs0
US20240276886A1 (en) * 2021-05-14 2024-08-15 The Regents Of The University Of California A processable, high-performance dielectric elastomer and multilayer dielectric elastomer actuator
US11801143B2 (en) * 2021-07-01 2023-10-31 Hyalex Orthopaedics, Inc. Multi-layered biomimetic osteochondral implants and methods of using thereof
CN115814152A (zh) * 2022-11-23 2023-03-21 中国人民解放军陆军军医大学 一种具有定向排列纤维微结构的高强度互穿网络水凝胶血管的制备方法

Family Cites Families (128)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4192827A (en) * 1974-06-27 1980-03-11 Ciba-Geigy Corporation Water-insoluble hydrophilic copolymers
DE2914737C3 (de) * 1979-04-11 1981-12-10 Feldmühle AG, 4000 Düsseldorf Hüftkopf-Kappen-Endoprothese
US4423099A (en) * 1980-07-28 1983-12-27 Ciba-Geigy Corporation Membrane modified hydrogels
US4320709A (en) * 1980-09-29 1982-03-23 Pyro-Sciences, Inc. Hazardous materials incineration system
US4439583A (en) * 1980-11-12 1984-03-27 Tyndale Plains-Hunter, Ltd. Polyurethane diacrylate compositions useful in forming canulae
US4502161A (en) * 1981-09-21 1985-03-05 Wall W H Prosthetic meniscus for the repair of joints
US4500676A (en) * 1983-12-15 1985-02-19 Biomatrix, Inc. Hyaluronate modified polymeric articles
US4575539A (en) * 1985-06-03 1986-03-11 E. R. Squibb & Sons, Inc. Drug delivery systems including novel interpenetrating polymer networks and method
US5114627A (en) * 1986-10-16 1992-05-19 Cbs Lens Method for producing a collagen hydrogel
US5112350A (en) * 1986-10-16 1992-05-12 Cbs Lens, A California General Partnership Method for locating on a cornea an artificial lens fabricated from a collagen-hydrogel for promoting epithelial cell growth and regeneration of the stroma
US5100689A (en) * 1987-04-10 1992-03-31 University Of Florida Surface modified surgical instruments, devices, implants, contact lenses and the like
US5094876A (en) * 1987-04-10 1992-03-10 University Of Florida Surface modified surgical instruments, devices, implants, contact lenses and the like
US5290548A (en) * 1987-04-10 1994-03-01 University Of Florida Surface modified ocular implants, surgical instruments, devices, prostheses, contact lenses and the like
US5282851A (en) * 1987-07-07 1994-02-01 Jacob Labarre Jean Intraocular prostheses
US5087392A (en) * 1988-05-31 1992-02-11 Sola Usa, Inc. Method of mold contact lenses
US5091205A (en) * 1989-01-17 1992-02-25 Union Carbide Chemicals & Plastics Technology Corporation Hydrophilic lubricious coatings
US5115056A (en) * 1989-06-20 1992-05-19 Ciba-Geigy Corporation Fluorine and/or silicone containing poly(alkylene-oxide)-block copolymers and contact lenses thereof
DE69104853T2 (de) * 1990-01-25 1995-03-16 Howmedica Knochenzement.
CA2101773A1 (en) * 1991-01-31 1992-08-01 Toyoichi Tanaka Interpenetrating-polymer network phase-transition gels
JP3007903B2 (ja) * 1991-03-29 2000-02-14 京セラ株式会社 人工椎間板
WO1993011751A1 (en) * 1991-12-18 1993-06-24 Scimed Life Systems, Inc. Lubricous polymer network
AU650156B2 (en) * 1992-08-05 1994-06-09 Lions Eye Institute Limited Keratoprosthesis and method of producing the same
WO1994003129A1 (en) * 1992-08-07 1994-02-17 Keravision Inc. Hybrid intrastromal corneal ring
JPH06287443A (ja) * 1993-04-01 1994-10-11 Bando Chem Ind Ltd 水膨潤性ポリウレタン組成物
US6140452A (en) * 1994-05-06 2000-10-31 Advanced Bio Surfaces, Inc. Biomaterial for in situ tissue repair
US5591170A (en) * 1994-10-14 1997-01-07 Genesis Orthopedics Intramedullary bone cutting saw
US5576072A (en) * 1995-02-01 1996-11-19 Schneider (Usa), Inc. Process for producing slippery, tenaciously adhering hydrogel coatings containing a polyurethane-urea polymer hydrogel commingled with at least one other, dissimilar polymer hydrogel
US6027742A (en) * 1995-05-19 2000-02-22 Etex Corporation Bioresorbable ceramic composites
JP3580611B2 (ja) * 1995-09-18 2004-10-27 日本エヌエスシー株式会社 架橋性ウレタン変成アクリル複合樹脂水分散体およびその製造方法
CN1098863C (zh) * 1995-11-15 2003-01-15 生化学株式会社 光固化交联透明质酸凝胶、其制备方法和生物医学材料
JP2000507997A (ja) * 1996-02-09 2000-06-27 サーフェス ソルーションズ ラボラトリーズ インコーポレイテッド 水性の親水性被覆組成物及びそれから製造した物品
US5817704A (en) * 1996-03-08 1998-10-06 The Procter & Gamble Company Heterogeneous foam materials
FR2749753B1 (fr) * 1996-06-14 1998-12-24 Mosseri Raphael Prothese totale de hanche destinee a etre posee par voie endo-articulaire et son dispositif ancillaire
CA2259364A1 (en) * 1996-08-13 1998-02-19 H.B. Fuller Licensing & Financing, Inc. Water-based sulfonated polymer compositions
EP0891753A4 (en) * 1996-11-13 1999-09-22 Menicon Co Ltd ARTIFICIAL CORNEA
DK0958495T3 (da) 1997-02-06 2003-03-10 Therasense Inc In vitro analysand sensor med lille volumen
US5904927A (en) * 1997-03-14 1999-05-18 Northeastern University Drug delivery using pH-sensitive semi-interpenetrating network hydrogels
US6224893B1 (en) * 1997-04-11 2001-05-01 Massachusetts Institute Of Technology Semi-interpenetrating or interpenetrating polymer networks for drug delivery and tissue engineering
ATE201031T1 (de) * 1997-04-14 2001-05-15 Degussa Verfahren zur modifizierung der oberfläche von polymersubstraten durch pfropfpolymerisation
US5981826A (en) * 1997-05-05 1999-11-09 Georgia Tech Research Corporation Poly(vinyl alcohol) cryogel
US6221467B1 (en) * 1997-06-03 2001-04-24 Scimed Life Systems, Inc. Coating gradient for lubricious coatings on balloon catheters
US6166127A (en) * 1997-06-27 2000-12-26 The Sherwin-Williams Company Interpenetrating networks of polymers
WO1999042528A2 (en) * 1998-02-23 1999-08-26 Mnemoscience Gmbh Shape memory polymers
US7019192B2 (en) * 1998-02-27 2006-03-28 Musculoskeletal Transplant Foundation Composition for filling bone defects
ES2165733T3 (es) * 1998-04-15 2002-03-16 Alcon Lab Inc Lentes intraoculares bicompuestas y metodo para su preparacion.
US6022925A (en) * 1998-06-23 2000-02-08 The Sherwin-Williams Company Partial interpenetrating networks of polymers
US6057406A (en) * 1998-08-03 2000-05-02 The University Of Southern Mississippi Functionally gradient polymeric materials
US6331578B1 (en) * 1998-11-18 2001-12-18 Josephine Turner Process for preparing interpenetrating polymer networks of controlled morphology
US6361560B1 (en) * 1998-12-23 2002-03-26 Anamed, Inc. Corneal implant and method of manufacture
US6376742B1 (en) * 1999-02-17 2002-04-23 Richard J. Zdrahala In vivo tissue engineering with biodegradable polymers
US6239209B1 (en) * 1999-02-23 2001-05-29 Reichhold, Inc. Air curable water-borne urethane-acrylic hybrids
US6332887B1 (en) * 1999-04-06 2001-12-25 Benjamin D. Knox Spinal fusion instrumentation system
US6673079B1 (en) * 1999-08-16 2004-01-06 Washington University Device for lengthening and reshaping bone by distraction osteogenesis
US7008635B1 (en) * 1999-09-10 2006-03-07 Genzyme Corporation Hydrogels for orthopedic repair
US6264695B1 (en) * 1999-09-30 2001-07-24 Replication Medical, Inc. Spinal nucleus implant
US7491236B2 (en) * 2000-02-16 2009-02-17 Trans1, Inc. Dual anchor prosthetic nucleus apparatus
US6626945B2 (en) * 2000-03-14 2003-09-30 Chondrosite, Llc Cartilage repair plug
US9314339B2 (en) * 2000-03-27 2016-04-19 Formae, Inc. Implants for replacing cartilage, with negatively-charged hydrogel surfaces and flexible matrix reinforcement
US6689165B2 (en) * 2000-03-31 2004-02-10 Board Of Supervisors Of Louisana State University And Agricultural And Mechanical College Surface modifications for enhanced epithelialization
US6846875B2 (en) * 2000-04-10 2005-01-25 Pharmacia Groningen Bv Hydrogels and methods for their production
US6372815B1 (en) * 2000-04-18 2002-04-16 Ocular Sciences Inc Ophthalmic lenses and compositions, and methods for producing same
CA2407154A1 (en) * 2000-04-27 2001-11-01 Verion, Inc Zero order release and temperature-controlled microcapsules and process for the preparation thereof
US7163541B2 (en) * 2002-12-03 2007-01-16 Arthrosurface Incorporated Tibial resurfacing system
US6520964B2 (en) * 2000-05-01 2003-02-18 Std Manufacturing, Inc. System and method for joint resurface repair
US6679917B2 (en) * 2000-05-01 2004-01-20 Arthrosurface, Incorporated System and method for joint resurface repair
US7678151B2 (en) * 2000-05-01 2010-03-16 Ek Steven W System and method for joint resurface repair
WO2002027388A1 (en) * 2000-09-28 2002-04-04 Novartis Ag Fenestrated lens for increased tear flow and method for making the same
US7335205B2 (en) * 2001-03-02 2008-02-26 Woodwelding Ag Implants, device and method for joining tissue parts
EP1423093A4 (en) * 2001-04-23 2005-11-30 Wisconsin Alumni Res Found BIFUNCTIONAL MODIFIED HYDROGEL
US20070083266A1 (en) * 2001-05-25 2007-04-12 Vertegen, Inc. Devices and methods for treating facet joints, uncovertebral joints, costovertebral joints and other joints
US6844028B2 (en) * 2001-06-26 2005-01-18 Accelr8 Technology Corporation Functional surface coating
US20040266941A1 (en) * 2001-06-27 2004-12-30 Houston Michael R. Biomedical molding materials from semi-solid precursors
US6747090B2 (en) * 2001-07-16 2004-06-08 Pharmacia Groningen Bv Compositions capable of forming hydrogels in the eye
DE10150737A1 (de) * 2001-10-15 2003-04-30 Hilti Ag Mehrkomponenten-Ortschaumsystem und dessen Verwendung
JP4095794B2 (ja) * 2001-12-03 2008-06-04 日東電工株式会社 複合フィルム及び半導体製品保持シート
US7458991B2 (en) * 2002-02-08 2008-12-02 Howmedica Osteonics Corp. Porous metallic scaffold for tissue ingrowth
CA2476315A1 (en) * 2002-02-15 2003-08-28 Zms, Llc Polymerization process and materials for biomedical applications
US6955716B2 (en) * 2002-03-01 2005-10-18 American Dental Association Foundation Self-hardening calcium phosphate materials with high resistance to fracture, controlled strength histories and tailored macropore formation rates
DE10217351B3 (de) * 2002-04-18 2004-02-12 Mnemoscience Gmbh Interpenetrierende Netzwerke
AU2002309026A1 (en) 2002-05-01 2003-11-17 Hokkaido Technology Licensing Office Co., Ltd. Gel having multiple network structure and method for preparation thereof
US7235102B2 (en) * 2002-05-10 2007-06-26 Ferree Bret A Prosthetic components with contained compressible resilient members
US7476398B1 (en) * 2002-06-28 2009-01-13 Universite Laval Corneal implant and uses thereof
CA2492030A1 (en) * 2002-07-11 2004-01-22 Advanced Bio Surfaces, Inc. Method and kit for interpositional arthroplasty
JP2005534485A (ja) * 2002-08-02 2005-11-17 アメリカ合衆国 架橋した一酸化窒素−放出ポリアミン被覆基質、それを含む組成物及びその製造方法
US20040028804A1 (en) * 2002-08-07 2004-02-12 Anderson Daniel G. Production of polymeric microarrays
US7959636B2 (en) * 2002-08-15 2011-06-14 Arthrex, Inc. Osteochondral repair using plug fashioned from whole distal femur or condyle formed of hydrogel composition
US7008226B2 (en) * 2002-08-23 2006-03-07 Woodwelding Ag Implant, in particular a dental implant
US7264634B2 (en) * 2002-09-20 2007-09-04 Arthrex, Inc. Method and instrumentation for osteochondral repair using preformed implants
US8673333B2 (en) * 2002-09-25 2014-03-18 The Johns Hopkins University Cross-linked polymer matrices, and methods of making and using same
US7049351B2 (en) * 2002-11-01 2006-05-23 Novartis Ag Moldings and preparation and uses thereof
US6733533B1 (en) * 2002-11-19 2004-05-11 Zimmer Technology, Inc. Artificial spinal disc
WO2004055057A1 (en) * 2002-12-18 2004-07-01 The University Of Melbourne Hydrogel preparation and process of manufacture thereof
US7220491B2 (en) * 2002-12-19 2007-05-22 Kimberly-Clark Worldwide, Inc. Lubricious coating for medical devices
EP1592728A2 (en) * 2003-01-16 2005-11-09 Carnegie-Mellon University Biodegradable polyurethanes and use thereof
US7160305B2 (en) * 2003-03-07 2007-01-09 Arthrex, Inc. Retrodrill technique for insertion of autograft, allograft or synthetic osteochondral implants
US7758497B2 (en) * 2003-06-20 2010-07-20 Contura A/S Endoscopic attachment device
WO2005016175A2 (en) * 2003-06-27 2005-02-24 Advanced Bio Surfaces, Inc. Meniscus preserving implant method and apparatus
US7176247B1 (en) * 2003-06-27 2007-02-13 The United States Of America As Represented By The Secretary Of The Army Interpenetrating polymer network
US7582698B2 (en) * 2003-07-02 2009-09-01 Lubrizol Advanced Materials, Inc. Water dispersions of non-uniform polyurethane particles
US20050065616A1 (en) * 2003-08-08 2005-03-24 Contura Sa Implantable hydrogel with resorbable shell for use as an endoprothesis
US10583220B2 (en) * 2003-08-11 2020-03-10 DePuy Synthes Products, Inc. Method and apparatus for resurfacing an articular surface
US20050054774A1 (en) * 2003-09-09 2005-03-10 Scimed Life Systems, Inc. Lubricious coating
US7544381B2 (en) * 2003-09-09 2009-06-09 Boston Scientific Scimed, Inc. Lubricious coatings for medical device
EP1722717B1 (en) * 2003-10-02 2013-06-19 Kevin A. Mansmann Hydrogels having charged surfaces for cartilage replacement
US20050113836A1 (en) * 2003-11-25 2005-05-26 Lozier Antony J. Expandable reamer
US8911234B2 (en) * 2004-02-20 2014-12-16 Woodwelding Ag Implant that can be implanted in osseous tissue, method for producing said implant and corresponding implant
US20070100457A1 (en) * 2004-03-04 2007-05-03 Hyde Edward R Jr Paramagnetic liquid interface
JP4709956B2 (ja) * 2004-06-18 2011-06-29 国立大学法人北海道大学 人工半月板
EP1611877A1 (en) * 2004-06-28 2006-01-04 Universidade de Coimbra Method for preparing sustained-release therapeutic ophthalmic articles using compressed fluids for impregnation of drugs
EP1627615A3 (en) * 2004-08-18 2006-11-02 Arthrex, Inc. Modular joint replacement implant with hydrogel surface
US20090088846A1 (en) * 2007-04-17 2009-04-02 David Myung Hydrogel arthroplasty device
US7857849B2 (en) * 2004-10-05 2010-12-28 The Board Of Trustees Of The Leland Stanford Junior Iniversity Artificial corneal implant
TW200640061A (en) * 2005-01-04 2006-11-16 Hitachi Chemical Co Ltd Phase separation type polymer electrolyte film, electrode/phase separation type polymer electrolyte film assembly employing the same, processes for producing the same, and fuel cell employing the same
US7651701B2 (en) * 2005-08-29 2010-01-26 Sanatis Gmbh Bone cement composition and method of making the same
US8420605B2 (en) * 2005-09-07 2013-04-16 The University Of Strathclyde Hydrogel compositions
US20070088444A1 (en) * 2005-10-13 2007-04-19 Robert A Hodorek Method for repairing a bone defect using a formable implant which hardens in vivo
JP2007210398A (ja) 2006-02-08 2007-08-23 Nissan Motor Co Ltd サスペンションのスプリングシート
US20080035344A1 (en) * 2006-08-07 2008-02-14 Nadir Odeh Delayed polyacrylamide-co-aluminum hydroxyl chloride gel
US20080058954A1 (en) * 2006-08-22 2008-03-06 Hai Trieu Methods of treating spinal injuries using injectable flowable compositions comprising organic materials
US7731988B2 (en) 2007-08-03 2010-06-08 Zimmer, Inc. Multi-polymer hydrogels
WO2009032071A2 (en) * 2007-08-29 2009-03-12 Spinemedica Corporation Orthopaedic cement mixtures with low weight percent polyvinyl alcohol (pva) solution
US8062739B2 (en) * 2007-08-31 2011-11-22 Zimmer, Inc. Hydrogels with gradient
US20100056646A1 (en) * 2008-03-12 2010-03-04 Shalaby Shalaby W Hydroswellable, segmented, aliphatic polyurethane ureas and intra-articular devices therefrom
US20090240337A1 (en) * 2008-03-21 2009-09-24 David Myung Methods, Devices and Compositions for Adhering Hydrated Polymer Implants to Bone
KR20110044219A (ko) * 2008-07-07 2011-04-28 바이오미메디카, 인코포레이티드 소수성 중합체에서 유래된 친수성 상호 침투 중합체 네트워크
US7874109B2 (en) 2008-07-30 2011-01-25 Honeywell International Inc. Fireproof panels and methods of fabricating the same
WO2012027678A1 (en) * 2010-08-27 2012-03-01 Biomimedica, Inc. Hydrophobic and hydrophilic interpenetrating polymer networks derived from hydrophobic polymers and methods of preparing the same
JP6115237B2 (ja) 2013-03-27 2017-04-19 セイコーエプソン株式会社 液体吐出装置

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