JP5746137B2 - アルギナーゼの部位指定的ペグ化並びにその抗がん剤及び抗ウイルス剤としての使用 - Google Patents
アルギナーゼの部位指定的ペグ化並びにその抗がん剤及び抗ウイルス剤としての使用 Download PDFInfo
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- JP5746137B2 JP5746137B2 JP2012501126A JP2012501126A JP5746137B2 JP 5746137 B2 JP5746137 B2 JP 5746137B2 JP 2012501126 A JP2012501126 A JP 2012501126A JP 2012501126 A JP2012501126 A JP 2012501126A JP 5746137 B2 JP5746137 B2 JP 5746137B2
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- arginase
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- bacillus
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- arginine
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| JP2023522888A (ja) * | 2020-04-17 | 2023-06-01 | バイオ－キャンサー・トリートメント・インターナショナル・リミテッド | アルギナーゼを使用してウイルス感染症を処置する方法 |
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| US9382525B2 (en) * | 2009-03-26 | 2016-07-05 | The Hong Kong Polytechnic University | Site-directed pegylation of arginases and the use thereof as anti-cancer and anti-viral agents |
| US8679479B2 (en) * | 2009-06-29 | 2014-03-25 | Aerase, Inc. | Methods for purifying pegylated arginase |
| ES2735530T3 (es) | 2010-01-26 | 2019-12-19 | Bioregency Inc | Composiciones y métodos relacionados con la argininosuccinato sintetasa |
| US20130295073A1 (en) * | 2010-12-21 | 2013-11-07 | Bio-Cancer Treatment International Ltd. | Use of pegylated recombinant human arginase for treatment of leukemia |
| CN103184208B (zh) | 2011-12-27 | 2015-09-16 | 拜奥生物科技（上海）有限公司 | 人精氨酸酶和定点聚乙二醇化人精氨酸酶及其应用 |
| US9011845B2 (en) | 2012-06-26 | 2015-04-21 | Board Of Supervisors Of Louisiana State University And Agricultural And Mechanical College | Methods for treatment of inflammatory and infectious viral diseases |
| US8877183B2 (en) | 2012-06-26 | 2014-11-04 | National Institutes Of Health (Nih) | Methods for treatment of ocular diseases |
| CA2944554A1 (en) | 2014-04-29 | 2015-11-05 | Bio-Cancer Treatment International Limited | Methods and compositions for modulating the immune system with arginase i |
| CN105112391B (zh) * | 2015-09-22 | 2018-07-06 | 浙江道尔生物科技有限公司 | 一种人源精氨酸酶突变体及其制备方法和用途 |
| CN106692961B (zh) * | 2015-11-17 | 2020-12-11 | 长春市福迪奥美科技有限公司 | 精氨酸酶组合物、精氨酸酶激活剂及其应用 |
| CN106434710A (zh) * | 2016-10-14 | 2017-02-22 | 江南大学 | 一种耐热精氨酸酶的基因表达序列和应用 |
| CN108265044B (zh) * | 2016-12-31 | 2021-05-11 | 江苏众红生物工程创药研究院有限公司 | 聚乙二醇定点修饰的精氨酸脱亚胺酶及其制备方法与应用 |
| TW201910513A (zh) * | 2017-08-16 | 2019-03-16 | 香港商鎧耀波麗堂（香港）有限公司 | 胺基酸耗竭治療的組合物及方法 |
| EP3802621B8 (en) | 2018-05-31 | 2025-10-15 | The Chinese University of Hong Kong | Composition and application of arginine-depleting agents for cancer, obesity, metabolic disorders, and related complications and comorbidities |
| CA3116736A1 (en) | 2018-10-19 | 2020-04-23 | Aerase, Inc. | Arginine depletion therapy for treatment of gamt deficiency |
| CN109793917B (zh) * | 2019-02-11 | 2020-10-09 | 海南建科药业有限公司 | 一种预防结直肠手术后吻合口瘘的凝胶的制备方法 |
| CA3149592A1 (en) | 2019-08-30 | 2021-03-04 | Scott W. Rowlinson | Methods for production of human recombinant arginase 1 and uses thereof |
| EP4069280A4 (en) * | 2019-12-02 | 2024-01-03 | The Hong Kong Polytechnic University | METHODS FOR INDUCING INTERMITTENT FASTING AND MODULATING AUTOPHAGY |
| WO2021228875A1 (en) * | 2020-05-14 | 2021-11-18 | Kyon Biotech Ag | Treatment of respiratory viral infections |
| US20230348884A1 (en) * | 2020-09-23 | 2023-11-02 | The Hong Kong Polytechnic University | Fluorescent Biosensor for Rapid Determination of L-arginine |
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| AU2003216109A1 (en) * | 2002-01-25 | 2003-09-02 | Cancer Treatments International | Therapeutic composition for treatment of cancer by arginine depletion |
| AU2003250371B2 (en) | 2002-06-20 | 2009-01-29 | Bio-Cancer Treatment International Limited | Pharmaceutical preparation and method of treatment of human malignancies with arginine deprivation |
| HK1053577A2 (en) * | 2002-06-20 | 2003-10-10 | Bio-Cancer Treatment International Limited | Pharmaceutical composition and method of treatment of human malignanices with arginine deprivation |
| EP1539210A4 (en) | 2002-09-06 | 2006-06-07 | Bayer Pharmaceuticals Corp | GLP-1 RECEPTOR MODIFIED AGONISTS AND THEIR PHARMACOLOGICAL METHODS OF USE |
| CN1745847A (zh) | 2004-09-08 | 2006-03-15 | 康达医药科技有限公司 | 用精氨酸酶治疗肝炎的药物组合物和方法 |
| WO2006058486A1 (en) | 2004-12-03 | 2006-06-08 | Bio-Cancer Treatment International Limited | Use of arginase in combination with 5fu and other compounds for treatment of human malignancies |
| US8679479B2 (en) * | 2009-06-29 | 2014-03-25 | Aerase, Inc. | Methods for purifying pegylated arginase |
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2010
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- 2010-03-26 CN CN201080023256.4A patent/CN102481345B/zh active Active
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- 2010-03-26 CA CA2756442A patent/CA2756442C/en active Active
- 2010-03-26 AU AU2010242422A patent/AU2010242422B2/en active Active
- 2010-03-26 JP JP2012501126A patent/JP5746137B2/ja active Active
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Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2023522888A (ja) * | 2020-04-17 | 2023-06-01 | バイオ－キャンサー・トリートメント・インターナショナル・リミテッド | アルギナーゼを使用してウイルス感染症を処置する方法 |
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| AU2010242422B2 (en) | 2014-12-04 |
| CA2756442A1 (en) | 2010-11-04 |
| EP2411040A1 (en) | 2012-02-01 |
| US20100247508A1 (en) | 2010-09-30 |
| EP2411040B1 (en) | 2015-09-23 |
| US8507245B2 (en) | 2013-08-13 |
| WO2010124547A1 (en) | 2010-11-04 |
| JP2012521201A (ja) | 2012-09-13 |
| CN102481345B (zh) | 2015-04-22 |
| CA2756442C (en) | 2016-03-29 |
| AU2010242422A1 (en) | 2011-10-27 |
| CN102481345A (zh) | 2012-05-30 |
| EP2411040A4 (en) | 2012-09-12 |
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