JP5726182B2 - 地黄、甘草、ヨクイニン、麦芽、カリン、五加皮及び葛根抽出物を含有する脂肪細胞分化促進組成物 - Google Patents
地黄、甘草、ヨクイニン、麦芽、カリン、五加皮及び葛根抽出物を含有する脂肪細胞分化促進組成物 Download PDFInfo
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- JP5726182B2 JP5726182B2 JP2012517409A JP2012517409A JP5726182B2 JP 5726182 B2 JP5726182 B2 JP 5726182B2 JP 2012517409 A JP2012517409 A JP 2012517409A JP 2012517409 A JP2012517409 A JP 2012517409A JP 5726182 B2 JP5726182 B2 JP 5726182B2
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- karin
- licorice
- malt
- skin
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- 150000003839 salts Chemical class 0.000 description 1
- 210000004761 scalp Anatomy 0.000 description 1
- 239000003352 sequestering agent Substances 0.000 description 1
- 239000000377 silicon dioxide Substances 0.000 description 1
- 235000019812 sodium carboxymethyl cellulose Nutrition 0.000 description 1
- 229920001027 sodium carboxymethylcellulose Polymers 0.000 description 1
- 159000000000 sodium salts Chemical class 0.000 description 1
- 239000007901 soft capsule Substances 0.000 description 1
- 239000007787 solid Substances 0.000 description 1
- 239000000243 solution Substances 0.000 description 1
- 238000000638 solvent extraction Methods 0.000 description 1
- 239000000600 sorbitol Substances 0.000 description 1
- 238000010186 staining Methods 0.000 description 1
- 239000012128 staining reagent Substances 0.000 description 1
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- 239000000758 substrate Substances 0.000 description 1
- 239000005720 sucrose Substances 0.000 description 1
- 239000000829 suppository Substances 0.000 description 1
- 239000004094 surface-active agent Substances 0.000 description 1
- 239000000375 suspending agent Substances 0.000 description 1
- 239000003765 sweetening agent Substances 0.000 description 1
- 238000003786 synthesis reaction Methods 0.000 description 1
- 239000006188 syrup Substances 0.000 description 1
- 235000020357 syrup Nutrition 0.000 description 1
- 239000000454 talc Substances 0.000 description 1
- 229910052623 talc Inorganic materials 0.000 description 1
- 239000002562 thickening agent Substances 0.000 description 1
- 230000000699 topical effect Effects 0.000 description 1
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- 229930003231 vitamin Natural products 0.000 description 1
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Classifications
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/25—Araliaceae (Ginseng family), e.g. ivy, aralia, schefflera or tetrapanax
- A61K36/254—Acanthopanax or Eleutherococcus
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
- A61K8/9783—Angiosperms [Magnoliophyta]
- A61K8/9789—Magnoliopsida [dicotyledons]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/48—Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
- A61K36/484—Glycyrrhiza (licorice)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/48—Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
- A61K36/488—Pueraria (kudzu)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/73—Rosaceae (Rose family), e.g. strawberry, chokeberry, blackberry, pear or firethorn
- A61K36/732—Chaenomeles, e.g. flowering quince
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/80—Scrophulariaceae (Figwort family)
- A61K36/804—Rehmannia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/88—Liliopsida (monocotyledons)
- A61K36/899—Poaceae or Gramineae (Grass family), e.g. bamboo, corn or sugar cane
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/88—Liliopsida (monocotyledons)
- A61K36/899—Poaceae or Gramineae (Grass family), e.g. bamboo, corn or sugar cane
- A61K36/8994—Coix (Job's tears)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
- A61K8/9783—Angiosperms [Magnoliophyta]
- A61K8/9794—Liliopsida [monocotyledons]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
- A61Q19/06—Preparations for care of the skin for countering cellulitis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
- A61Q19/08—Anti-ageing preparations
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
- A61K2800/80—Process related aspects concerning the preparation of the cosmetic composition or the storage or application thereof
- A61K2800/91—Injection
Landscapes
- Health & Medical Sciences (AREA)
- Natural Medicines & Medicinal Plants (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Microbiology (AREA)
- Biotechnology (AREA)
- Engineering & Computer Science (AREA)
- Botany (AREA)
- Mycology (AREA)
- Epidemiology (AREA)
- Pharmacology & Pharmacy (AREA)
- Medical Informatics (AREA)
- Alternative & Traditional Medicine (AREA)
- Medicinal Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Birds (AREA)
- Dermatology (AREA)
- Gerontology & Geriatric Medicine (AREA)
- Medicines Containing Plant Substances (AREA)
- Cosmetics (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| KR10-2009-0058929 | 2009-06-30 | ||
| KR1020090058929A KR20110001407A (ko) | 2009-06-30 | 2009-06-30 | 지황, 감초, 의이인, 맥아, 모과, 오가피, 또는 갈근 추출물을 함유하는 지방 세포 분화 촉진 조성물 |
| PCT/KR2010/004243 WO2011002223A2 (ko) | 2009-06-30 | 2010-06-30 | 지황, 감초, 의이인, 맥아, 모과, 오가피 또는 갈근 추출물을 함유하는 지방 세포 분화 촉진 조성물 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2012532098A JP2012532098A (ja) | 2012-12-13 |
| JP2012532098A5 JP2012532098A5 (enExample) | 2013-08-15 |
| JP5726182B2 true JP5726182B2 (ja) | 2015-05-27 |
Family
ID=43411601
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2012517409A Expired - Fee Related JP5726182B2 (ja) | 2009-06-30 | 2010-06-30 | 地黄、甘草、ヨクイニン、麦芽、カリン、五加皮及び葛根抽出物を含有する脂肪細胞分化促進組成物 |
Country Status (5)
| Country | Link |
|---|---|
| US (1) | US9028885B2 (enExample) |
| JP (1) | JP5726182B2 (enExample) |
| KR (1) | KR20110001407A (enExample) |
| CN (1) | CN102470097B (enExample) |
| WO (1) | WO2011002223A2 (enExample) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR101710005B1 (ko) * | 2016-05-10 | 2017-03-08 | 주식회사 코리아나화장품 | 천정팔진단을 유효성분으로 함유하는 화장료 조성물 |
Families Citing this family (26)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2013032331A (ja) * | 2011-07-06 | 2013-02-14 | Kose Corp | 脂質産生抑制剤、皮脂産生抑制剤およびトリアシルグリセロール産生抑制剤 |
| JP5947047B2 (ja) * | 2012-02-06 | 2016-07-06 | 花王株式会社 | Ｐｐａｒ活性化剤 |
| CN104116655A (zh) * | 2013-04-26 | 2014-10-29 | 上海珍馨化工科技有限公司 | 一种薏苡仁面贴膜用乳液、面贴膜及其制备方法 |
| JP2015093848A (ja) * | 2013-11-12 | 2015-05-18 | 丸善製薬株式会社 | 皮膚化粧料及び頭髪化粧料 |
| CN103690448A (zh) * | 2013-12-26 | 2014-04-02 | 蔡旭升 | 一种具有祛斑功效的面膜 |
| KR102175468B1 (ko) | 2014-01-20 | 2020-11-06 | (주)아모레퍼시픽 | 히드록시 피라논 유도체 화합물을 포함하는 지방세포 분화 촉진용 화장료 조성물 |
| CN103876150B (zh) * | 2014-04-06 | 2015-10-28 | 王兴伟 | 一种中药组合物 |
| KR102294232B1 (ko) | 2014-04-30 | 2021-08-26 | 킴벌리-클라크 월드와이드, 인크. | 산화 스트레스를 감소시키기 위한 조성물 및 방법 |
| WO2015167547A1 (en) | 2014-04-30 | 2015-11-05 | Kimberly-Clark Worldwide, Inc. | Methods of reducing signs of skin aging |
| AU2014392682B2 (en) * | 2014-04-30 | 2020-07-09 | Kimberly-Clark Worldwide, Inc. | Methods of reducing signs of skin aging using a combination of extracts |
| BR112016023653B1 (pt) | 2014-04-30 | 2020-12-08 | Kimberly-Clark Worldwide, Inc | composição tópica |
| US10123964B2 (en) | 2014-04-30 | 2018-11-13 | Kimberly-Clark Worldwide, Inc. | Topical composition including a combination of extracts for reducing signs of skin aging |
| US11154491B2 (en) | 2014-04-30 | 2021-10-26 | Kimberly-Clark Worldwide, Inc. | Use of Undaria extract to reduce signs of skin aging |
| KR102224631B1 (ko) * | 2014-05-13 | 2021-03-08 | 주식회사 코리아나화장품 | 지황 추출물을 함유하는 화장료 조성물 |
| CN103961294A (zh) * | 2014-05-31 | 2014-08-06 | 广州丹奇日用化工厂有限公司 | 一种地黄提取液及其制备方法和应用 |
| JP6427375B2 (ja) * | 2014-09-25 | 2018-11-21 | 花王株式会社 | インテグリン発現促進剤 |
| JP2016104707A (ja) * | 2014-12-01 | 2016-06-09 | 株式会社クラブコスメチックス | コラゲナーゼ活性阻害剤 |
| KR102560153B1 (ko) | 2015-04-17 | 2023-07-26 | 주식회사 엘지생활건강 | 피부 볼륨 증진용 용해성 미세바늘 패치 |
| CN106333880B (zh) * | 2016-10-21 | 2019-12-17 | 皖南医学院 | 一种稀薄乳液基质的爽肤水及其制备方法 |
| KR102700608B1 (ko) * | 2016-11-29 | 2024-08-30 | 주식회사 엘지생활건강 | 레마피크로사이드를 포함하는 화장료 조성물 |
| CN108813608A (zh) * | 2018-05-25 | 2018-11-16 | 陕西黄龙国寿堂生物工程有限公司 | 一种沙棘刺五加膏的制作方法 |
| JP7338842B2 (ja) * | 2018-10-19 | 2023-09-05 | 丸善製薬株式会社 | しわ改善用組成物およびしわ改善用皮膚化粧料 |
| JPWO2021167097A1 (enExample) * | 2020-02-19 | 2021-08-26 | ||
| JP7655530B2 (ja) * | 2020-12-11 | 2025-04-02 | 日本メナード化粧品株式会社 | 真皮幹細胞の分化促進剤 |
| JP2023086263A (ja) * | 2021-12-10 | 2023-06-22 | 日本メナード化粧品株式会社 | コラーゲン産生促進剤、ｍｍｐ阻害剤、ヒアルロン酸産生促進剤、細胞増殖促進剤及び内用剤 |
| CN118995592B (zh) * | 2024-09-24 | 2025-07-01 | 广东医科大学附属医院 | 五加皮外泌体样纳米囊泡成骨诱导培养基及其制备方法以及成骨诱导分化方法和用途 |
Family Cites Families (22)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP3536111B2 (ja) * | 1992-06-29 | 2004-06-07 | 株式会社ナリス化粧品 | ムコ多糖類断片化抑制剤および化粧料 |
| JPH08283172A (ja) | 1995-04-14 | 1996-10-29 | Kose Corp | 活性酸素消去剤及びこれを含有する皮膚外用剤 |
| JP3542665B2 (ja) * | 1995-07-07 | 2004-07-14 | 株式会社資生堂 | 抗老化皮膚外用剤、コラーゲン架橋阻害皮膚外用剤及び抗紫外線皮膚外用剤 |
| JPH09315988A (ja) * | 1996-05-27 | 1997-12-09 | Shiseido Co Ltd | 抗酸化剤 |
| JPH10130162A (ja) | 1996-10-31 | 1998-05-19 | Kanebo Ltd | ヒアルロン酸分解阻害剤、ヒアルロン酸異常分解疾患治療剤および化粧料 |
| JP4035258B2 (ja) * | 1999-05-10 | 2008-01-16 | 花王株式会社 | 皮膚外用剤 |
| JP2001288066A (ja) * | 2000-03-31 | 2001-10-16 | Shiseido Co Ltd | 皮膚バリアー機能改善剤 |
| BR0111109A (pt) | 2000-05-23 | 2003-03-11 | Oreal | Uso de extratos de vegetais em uma composição cosmética para proteção de fibras queratinosas |
| CN1277839A (zh) | 2000-05-23 | 2000-12-27 | 李雪涛 | 竹营养面膜及其生物制作方法 |
| JP2002097149A (ja) * | 2000-09-20 | 2002-04-02 | Noevir Co Ltd | 皮膚外用剤 |
| JP5122060B2 (ja) * | 2002-06-25 | 2013-01-16 | 株式会社 資生堂 | 抗老化剤 |
| JP2004075573A (ja) * | 2002-08-12 | 2004-03-11 | Naris Cosmetics Co Ltd | 皮膚化粧料 |
| CN100463666C (zh) * | 2002-11-07 | 2009-02-25 | 株式会社高丝 | 皮肤外用剂组成物 |
| US20040223942A1 (en) * | 2003-03-06 | 2004-11-11 | Kao Corporation | Skin aging-preventing or improving agent |
| KR20060116206A (ko) * | 2003-11-17 | 2006-11-14 | 가부시키가이샤 게오 | 화장 조성물 |
| US20050154066A1 (en) * | 2004-01-08 | 2005-07-14 | Kaneka Corporation | Antiaging composition |
| EP1604647B1 (en) * | 2004-05-12 | 2008-05-07 | Chisso Corporation | Cosmetic composition containing polyorganosiloxane-containing epsilon-polylysine polymer, and polyhydric alcohol, and production thereof |
| KR100611796B1 (ko) * | 2005-01-28 | 2006-08-10 | 한국화장품주식회사 | 십전대보단 성분을 함유한 화장료 조성물 및 이의 제조 방법 |
| KR101252548B1 (ko) | 2006-01-19 | 2013-04-08 | (주)아모레퍼시픽 | 해송자 추출물을 유효성분으로 함유하는 화장료 조성물 |
| KR20080065726A (ko) | 2007-01-10 | 2008-07-15 | 주식회사 코리아나화장품 | 한방 생약 추출물을 배합시킨 액정 유화 베이스를 포함하는피부보호용 화장료 조성물 |
| CN101015514B (zh) | 2007-01-15 | 2010-04-14 | 焦克明 | 驱蚊防晒润肤液 |
| JP2009073777A (ja) * | 2007-09-21 | 2009-04-09 | Kao Corp | 化粧料 |
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2009
- 2009-06-30 KR KR1020090058929A patent/KR20110001407A/ko not_active Ceased
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2010
- 2010-06-30 WO PCT/KR2010/004243 patent/WO2011002223A2/ko not_active Ceased
- 2010-06-30 JP JP2012517409A patent/JP5726182B2/ja not_active Expired - Fee Related
- 2010-06-30 US US13/381,169 patent/US9028885B2/en not_active Expired - Fee Related
- 2010-06-30 CN CN201080038210XA patent/CN102470097B/zh not_active Expired - Fee Related
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR101710005B1 (ko) * | 2016-05-10 | 2017-03-08 | 주식회사 코리아나화장품 | 천정팔진단을 유효성분으로 함유하는 화장료 조성물 |
Also Published As
| Publication number | Publication date |
|---|---|
| WO2011002223A3 (ko) | 2011-05-19 |
| CN102470097A (zh) | 2012-05-23 |
| HK1164746A1 (en) | 2012-09-28 |
| WO2011002223A2 (ko) | 2011-01-06 |
| US20120107427A1 (en) | 2012-05-03 |
| US9028885B2 (en) | 2015-05-12 |
| JP2012532098A (ja) | 2012-12-13 |
| KR20110001407A (ko) | 2011-01-06 |
| CN102470097B (zh) | 2013-06-12 |
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