JP5720233B2 - マイクロチップ及び微小粒子分取装置 - Google Patents

マイクロチップ及び微小粒子分取装置 Download PDF

Info

Publication number
JP5720233B2
JP5720233B2 JP2010282167A JP2010282167A JP5720233B2 JP 5720233 B2 JP5720233 B2 JP 5720233B2 JP 2010282167 A JP2010282167 A JP 2010282167A JP 2010282167 A JP2010282167 A JP 2010282167A JP 5720233 B2 JP5720233 B2 JP 5720233B2
Authority
JP
Japan
Prior art keywords
channel
microchip
microparticles
negative pressure
suction
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
JP2010282167A
Other languages
English (en)
Japanese (ja)
Other versions
JP2012127922A (ja
JP2012127922A5 (enExample
Inventor
達巳 伊藤
達巳 伊藤
角田　正也
正也 角田
今西　慎悟
慎悟 今西
尚 新田
尚 新田
孝治 二村
孝治 二村
亨 高清水
亨 高清水
芦崎　浩二
浩二 芦崎
古木　基裕
基裕 古木
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sony Corp
Original Assignee
Sony Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sony Corp filed Critical Sony Corp
Priority to JP2010282167A priority Critical patent/JP5720233B2/ja
Priority to US13/315,052 priority patent/US8487273B2/en
Priority to CN201110409903.1A priority patent/CN102564925B/zh
Publication of JP2012127922A publication Critical patent/JP2012127922A/ja
Publication of JP2012127922A5 publication Critical patent/JP2012127922A5/ja
Application granted granted Critical
Publication of JP5720233B2 publication Critical patent/JP5720233B2/ja
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Images

Classifications

    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
    • B01L3/5027—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
    • B01L3/502769—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip characterised by multiphase flow arrangements
    • B01L3/502776—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip characterised by multiphase flow arrangements specially adapted for focusing or laminating flows
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
    • B01L3/5027—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
    • B01L3/502761—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip specially adapted for handling suspended solids or molecules independently from the bulk fluid flow, e.g. for trapping or sorting beads, for physically stretching molecules
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2200/00—Solutions for specific problems relating to chemical or physical laboratory apparatus
    • B01L2200/06—Fluid handling related problems
    • B01L2200/0647—Handling flowable solids, e.g. microscopic beads, cells, particles
    • B01L2200/0652—Sorting or classification of particles or molecules
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2200/00—Solutions for specific problems relating to chemical or physical laboratory apparatus
    • B01L2200/06—Fluid handling related problems
    • B01L2200/0647—Handling flowable solids, e.g. microscopic beads, cells, particles
    • B01L2200/0668—Trapping microscopic beads
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/08—Geometry, shape and general structure
    • B01L2300/0809—Geometry, shape and general structure rectangular shaped
    • B01L2300/0816—Cards, e.g. flat sample carriers usually with flow in two horizontal directions
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/08—Geometry, shape and general structure
    • B01L2300/0861—Configuration of multiple channels and/or chambers in a single devices
    • B01L2300/0864—Configuration of multiple channels and/or chambers in a single devices comprising only one inlet and multiple receiving wells, e.g. for separation, splitting
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/08—Geometry, shape and general structure
    • B01L2300/0861—Configuration of multiple channels and/or chambers in a single devices
    • B01L2300/0867—Multiple inlets and one sample wells, e.g. mixing, dilution
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2400/00—Moving or stopping fluids
    • B01L2400/04—Moving fluids with specific forces or mechanical means
    • B01L2400/0403—Moving fluids with specific forces or mechanical means specific forces
    • B01L2400/0415—Moving fluids with specific forces or mechanical means specific forces electrical forces, e.g. electrokinetic
    • B01L2400/0418—Moving fluids with specific forces or mechanical means specific forces electrical forces, e.g. electrokinetic electro-osmotic flow [EOF]
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2400/00—Moving or stopping fluids
    • B01L2400/04—Moving fluids with specific forces or mechanical means
    • B01L2400/0403—Moving fluids with specific forces or mechanical means specific forces
    • B01L2400/0433—Moving fluids with specific forces or mechanical means specific forces vibrational forces
    • B01L2400/0439—Moving fluids with specific forces or mechanical means specific forces vibrational forces ultrasonic vibrations, vibrating piezo elements
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2400/00—Moving or stopping fluids
    • B01L2400/04—Moving fluids with specific forces or mechanical means
    • B01L2400/0475—Moving fluids with specific forces or mechanical means specific mechanical means and fluid pressure
    • B01L2400/0487—Moving fluids with specific forces or mechanical means specific mechanical means and fluid pressure fluid pressure, pneumatics
    • B01L2400/049—Moving fluids with specific forces or mechanical means specific mechanical means and fluid pressure fluid pressure, pneumatics vacuum
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2400/00—Moving or stopping fluids
    • B01L2400/06—Valves, specific forms thereof
    • B01L2400/0622—Valves, specific forms thereof distribution valves, valves having multiple inlets and/or outlets, e.g. metering valves, multi-way valves
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
    • G01N15/10—Investigating individual particles
    • G01N15/14—Optical investigation techniques, e.g. flow cytometry
    • G01N15/1404—Handling flow, e.g. hydrodynamic focusing
    • G01N15/1409—Handling samples, e.g. injecting samples
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
    • G01N15/10—Investigating individual particles
    • G01N15/14—Optical investigation techniques, e.g. flow cytometry
    • G01N15/1484—Optical investigation techniques, e.g. flow cytometry microstructural devices

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Dispersion Chemistry (AREA)
  • Analytical Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Hematology (AREA)
  • Clinical Laboratory Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Physics & Mathematics (AREA)
  • Fluid Mechanics (AREA)
  • Automatic Analysis And Handling Materials Therefor (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
JP2010282167A 2010-12-17 2010-12-17 マイクロチップ及び微小粒子分取装置 Active JP5720233B2 (ja)

Priority Applications (3)

Application Number Priority Date Filing Date Title
JP2010282167A JP5720233B2 (ja) 2010-12-17 2010-12-17 マイクロチップ及び微小粒子分取装置
US13/315,052 US8487273B2 (en) 2010-12-17 2011-12-08 Microchip and particulate fractional collection apparatus
CN201110409903.1A CN102564925B (zh) 2010-12-17 2011-12-09 微芯片和微粒分取装置

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP2010282167A JP5720233B2 (ja) 2010-12-17 2010-12-17 マイクロチップ及び微小粒子分取装置

Publications (3)

Publication Number Publication Date
JP2012127922A JP2012127922A (ja) 2012-07-05
JP2012127922A5 JP2012127922A5 (enExample) 2013-12-19
JP5720233B2 true JP5720233B2 (ja) 2015-05-20

Family

ID=46233158

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2010282167A Active JP5720233B2 (ja) 2010-12-17 2010-12-17 マイクロチップ及び微小粒子分取装置

Country Status (2)

Country Link
US (1) US8487273B2 (enExample)
JP (1) JP5720233B2 (enExample)

Families Citing this family (47)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9943847B2 (en) 2002-04-17 2018-04-17 Cytonome/St, Llc Microfluidic system including a bubble valve for regulating fluid flow through a microchannel
US6808075B2 (en) 2002-04-17 2004-10-26 Cytonome, Inc. Method and apparatus for sorting particles
US6976590B2 (en) 2002-06-24 2005-12-20 Cytonome, Inc. Method and apparatus for sorting particles
CN1886315B (zh) 2003-10-30 2012-11-28 塞通诺米/St有限责任公司 多层流体动力学鞘流结构
US9260693B2 (en) 2004-12-03 2016-02-16 Cytonome/St, Llc Actuation of parallel microfluidic arrays
JP6172147B2 (ja) * 2012-07-18 2017-08-02 ソニー株式会社 微小粒子分取装置及び微小粒子分取方法
JP6036496B2 (ja) * 2012-07-24 2016-11-30 ソニー株式会社 微小粒子分取方法
JP5910412B2 (ja) * 2012-08-16 2016-04-27 ソニー株式会社 微小粒子分取方法及び微小粒子分取用マイクロチップ
WO2014038640A1 (ja) * 2012-09-06 2014-03-13 古河電気工業株式会社 検体識別分取装置および検体識別分取方法
US9731293B2 (en) * 2012-10-03 2017-08-15 The United States Of America, As Represented By The Secretary Of The Navy Paired laser and electrokinetic separation, manipulation, and analysis device
US10583439B2 (en) 2013-03-14 2020-03-10 Cytonome/St, Llc Hydrodynamic focusing apparatus and methods
JP6186812B2 (ja) 2013-04-04 2017-08-30 ソニー株式会社 粒子分取装置及び粒子分取方法
CN115266543A (zh) * 2013-10-30 2022-11-01 Abs全球公司 识别对象的装置及相关方法
CN106536059B (zh) 2014-06-09 2019-01-11 阿森特生物纳米科技股份有限公司 用于颗粒的控制和分拣系统
CN105642173B (zh) * 2016-01-11 2018-09-14 中国科学院理化技术研究所 一种电渗微混合器
JP6953679B2 (ja) 2016-03-30 2021-10-27 ソニーグループ株式会社 試料分取キット、試料分取装置
CN109313117B (zh) 2016-07-26 2022-01-14 惠普发展公司，有限责任合伙企业 微流体装置、用于控制流体的方法以及微流体系统
JP6783153B2 (ja) * 2017-01-13 2020-11-11 アークレイ株式会社 フローセル及び測定装置
JP6919215B2 (ja) 2017-02-17 2021-08-18 ソニーグループ株式会社 マイクロチップ及び微小粒子分取装置
EP3594654B1 (en) * 2017-03-08 2025-05-14 Sony Group Corporation Cell sample liquid feed bag, cell sample liquid feed method, and cell sample liquid feed device
EP3599456B1 (en) 2017-03-31 2025-06-11 Sony Group Corporation Channel unit and microparticle analysis device
US11525767B2 (en) 2017-05-24 2022-12-13 Sony Corporation Optimizing method of suction condition of microparticle and microparticle fractionating device
EP3633347B1 (en) 2017-05-26 2023-07-19 Sony Group Corporation Method for optimizing suction conditions for microparticles, and microparticle separation device
CN113474084B (zh) * 2017-06-28 2024-02-09 生物辐射实验室股份有限公司 用于液滴检测的系统和方法
JP6508265B2 (ja) * 2017-08-02 2019-05-08 ソニー株式会社 粒子分取装置及び粒子分取方法
US11045805B2 (en) 2017-11-01 2021-06-29 Bio-Rad Laboratories, Inc. Microfluidic system and method for arranging objects
CN111771116B (zh) 2018-03-02 2024-03-05 索尼公司 用于优化微粒吸入条件的方法、微粒分选装置和系统
JP7059747B2 (ja) * 2018-03-27 2022-04-26 ソニーグループ株式会社 微小粒子分取方法、微小粒子分取用プログラム及び微小粒子分取用システム
JP2019190991A (ja) * 2018-04-25 2019-10-31 ソニー株式会社 微小粒子測定装置及び微小粒子測定方法
WO2019230489A1 (ja) * 2018-06-01 2019-12-05 ソニー株式会社 マイクロチップ及びサンプル分取キット
JP7287399B2 (ja) 2018-09-10 2023-06-06 ソニーグループ株式会社 微小粒子分取用流路ユニット及び微小粒子分取装置
WO2020054735A1 (en) 2018-09-10 2020-03-19 Sony Corporation Microparticle sorting device, cell therapeutic agent manufacturing device, microparticle sorting method and program
JP6791295B2 (ja) * 2019-04-04 2020-11-25 ソニー株式会社 粒子分取装置及び粒子分取方法
JP7312135B2 (ja) * 2019-04-08 2023-07-20 アークレイ株式会社 送液方法及び分析装置
JP7388131B2 (ja) * 2019-10-31 2023-11-29 ソニーグループ株式会社 微小粒子回収方法、微小粒子分取用マイクロチップ、微小粒子回収装置、エマルションの製造方法、及びエマルション
JP2021071441A (ja) 2019-11-01 2021-05-06 ソニー株式会社 チップ固定装置及び粒子検査装置
CN114556085A (zh) 2019-11-05 2022-05-27 索尼集团公司 微粒分选微芯片的灌注方法、微粒分选方法、微粒分选装置和程序
US20220349806A1 (en) 2019-11-06 2022-11-03 Sony Group Corporation Position adjusting method, microparticle analysis device, and program
WO2021090708A1 (ja) 2019-11-06 2021-05-14 ソニー株式会社 光学測定装置及び情報処理システム
JP2021076455A (ja) 2019-11-07 2021-05-20 ソニー株式会社 分取制御装置、該分取制御装置を用いた粒子分取装置及び粒子分取システム、並びに分取制御方法、及び制御プログラム
JP7528950B2 (ja) 2019-11-20 2024-08-06 ソニーグループ株式会社 マイクロチップ、サンプル分取キット及び微小粒子分取装置
JP2022017705A (ja) 2020-07-14 2022-01-26 ソニーグループ株式会社 微小粒子分取装置、微小粒子分取方法、プログラム、及び微小粒子分取システム
JP2020190575A (ja) * 2020-08-25 2020-11-26 ソニー株式会社 粒子分取装置及び粒子分取方法
CN116670493A (zh) 2021-01-14 2023-08-29 索尼集团公司 粒子分析器、粒子分析方法和光学测量装置
CN117015696A (zh) 2021-03-26 2023-11-07 索尼集团公司 生物粒子分选装置和用于调整生物粒子分选装置的分选条件的方法
JPWO2022209374A1 (enExample) 2021-03-31 2022-10-06
JPWO2024071301A1 (enExample) * 2022-09-29 2024-04-04

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH01170853A (ja) * 1987-12-25 1989-07-05 Hitachi Ltd 細胞選別装置
JP2001050887A (ja) * 1999-08-11 2001-02-23 Sysmex Corp 粒子分析装置
JP2003274924A (ja) 2002-03-26 2003-09-30 Kikuchi Jun 細胞分離方法及び装置
EP2666849A3 (en) * 2002-04-01 2014-05-28 Fluidigm Corporation Microfluidic particle-analysis systems
AU2003228630B2 (en) * 2002-04-17 2009-10-22 Cytonome/St, Llc Method and apparatus for sorting particles
WO2004025266A2 (en) 2002-09-16 2004-03-25 Cytonome, Inc Method and apparatus for sorting particles
JP4203548B2 (ja) 2002-09-23 2009-01-07 禅 高村 細胞分離方法、細胞分離装置および細胞分離装置の製造方法
US20080213821A1 (en) * 2004-05-06 2008-09-04 Nanyang Technological University Microfluidic Cell Sorter System
US20070240495A1 (en) 2004-05-25 2007-10-18 Shuzo Hirahara Microfluidic Device and Analyzing/Sorting Apparatus Using The Same
JP4679847B2 (ja) 2004-07-12 2011-05-11 オリンパス株式会社 細胞の解析方法
JP2007330201A (ja) 2006-06-16 2007-12-27 Ab Size:Kk 細胞分取用マイクロチップ及び細胞分取方法
KR20080110167A (ko) * 2007-06-14 2008-12-18 삼성전자주식회사 시료 중의 입자를 집중화하고 검출하기 위한 장치 및 그를제조하는 방법
JP2010151777A (ja) * 2008-11-19 2010-07-08 Sony Corp 微小粒子解析装置、微小粒子解析用マイクロチップ及び微小粒子解析方法

Also Published As

Publication number Publication date
CN102564925A (zh) 2012-07-11
US20120153185A1 (en) 2012-06-21
JP2012127922A (ja) 2012-07-05
US8487273B2 (en) 2013-07-16

Similar Documents

Publication Publication Date Title
JP5720233B2 (ja) マイクロチップ及び微小粒子分取装置
JP7354368B2 (ja) マイクロ流体チャネルを使用してマイクロ粒子のバルク選別を行う方法及び装置
CN101609088B (zh) 微流控芯片和微流控芯片中的送流方法
US8096421B2 (en) Micro-fluidic chip, micro-particle sorting device and flow controlling method
KR101683066B1 (ko) 미소 입자 분취를 위한 장치 및 마이크로칩
KR101615177B1 (ko) 마이크로칩, 유로 구조, 유체 분석 장치, 미소입자 분별 장치 및 송액 방법
US9459182B2 (en) Microchip and particle analyzing apparatus
JP6954979B2 (ja) 音響場を用いて整列された自由飛行液滴中の粒子を分配するための装置および方法
JP6922281B2 (ja) マイクロチップ、及び微小粒子測定装置
CN108432132A (zh) 微流体颗粒操纵
JP2010252785A (ja) 細胞濃縮分離装置
JP2021181991A (ja) マイクロチップ及び微小粒子分取装置
US20220381670A1 (en) Sorting control device, particle sorting device and particle sorting system using sorting control device, sorting control method, and control program
JP5316530B2 (ja) マイクロチップとその流路構造
CN102564925B (zh) 微芯片和微粒分取装置
JP7287399B2 (ja) 微小粒子分取用流路ユニット及び微小粒子分取装置
US20240238786A1 (en) Droplet sortation

Legal Events

Date Code Title Description
A521 Request for written amendment filed

Free format text: JAPANESE INTERMEDIATE CODE: A523

Effective date: 20131105

A621 Written request for application examination

Free format text: JAPANESE INTERMEDIATE CODE: A621

Effective date: 20131105

A977 Report on retrieval

Free format text: JAPANESE INTERMEDIATE CODE: A971007

Effective date: 20140312

A131 Notification of reasons for refusal

Free format text: JAPANESE INTERMEDIATE CODE: A131

Effective date: 20141216

A521 Request for written amendment filed

Free format text: JAPANESE INTERMEDIATE CODE: A523

Effective date: 20150129

TRDD Decision of grant or rejection written
A01 Written decision to grant a patent or to grant a registration (utility model)

Free format text: JAPANESE INTERMEDIATE CODE: A01

Effective date: 20150224

A61 First payment of annual fees (during grant procedure)

Free format text: JAPANESE INTERMEDIATE CODE: A61

Effective date: 20150309

R151 Written notification of patent or utility model registration

Ref document number: 5720233

Country of ref document: JP

Free format text: JAPANESE INTERMEDIATE CODE: R151

R250 Receipt of annual fees

Free format text: JAPANESE INTERMEDIATE CODE: R250

R250 Receipt of annual fees

Free format text: JAPANESE INTERMEDIATE CODE: R250

R250 Receipt of annual fees

Free format text: JAPANESE INTERMEDIATE CODE: R250