JP5720233B2 - マイクロチップ及び微小粒子分取装置 - Google Patents

マイクロチップ及び微小粒子分取装置 Download PDF

Info

Publication number
JP5720233B2
JP5720233B2 JP2010282167A JP2010282167A JP5720233B2 JP 5720233 B2 JP5720233 B2 JP 5720233B2 JP 2010282167 A JP2010282167 A JP 2010282167A JP 2010282167 A JP2010282167 A JP 2010282167A JP 5720233 B2 JP5720233 B2 JP 5720233B2
Authority
JP
Japan
Prior art keywords
channel
microchip
microparticles
negative pressure
suction
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
JP2010282167A
Other languages
English (en)
Japanese (ja)
Other versions
JP2012127922A (ja
JP2012127922A5 (OSRAM
Inventor
達巳 伊藤
達巳 伊藤
角田　正也
正也 角田
今西　慎悟
慎悟 今西
尚 新田
尚 新田
孝治 二村
孝治 二村
亨 高清水
亨 高清水
芦崎　浩二
浩二 芦崎
古木　基裕
基裕 古木
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sony Corp
Original Assignee
Sony Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sony Corp filed Critical Sony Corp
Priority to JP2010282167A priority Critical patent/JP5720233B2/ja
Priority to US13/315,052 priority patent/US8487273B2/en
Priority to CN201110409903.1A priority patent/CN102564925B/zh
Publication of JP2012127922A publication Critical patent/JP2012127922A/ja
Publication of JP2012127922A5 publication Critical patent/JP2012127922A5/ja
Application granted granted Critical
Publication of JP5720233B2 publication Critical patent/JP5720233B2/ja
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Images

Classifications

    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
    • B01L3/5027—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
    • B01L3/502769—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip characterised by multiphase flow arrangements
    • B01L3/502776—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip characterised by multiphase flow arrangements specially adapted for focusing or laminating flows
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
    • B01L3/5027—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
    • B01L3/502761—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip specially adapted for handling suspended solids or molecules independently from the bulk fluid flow, e.g. for trapping or sorting beads, for physically stretching molecules
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2200/00—Solutions for specific problems relating to chemical or physical laboratory apparatus
    • B01L2200/06—Fluid handling related problems
    • B01L2200/0647—Handling flowable solids, e.g. microscopic beads, cells, particles
    • B01L2200/0652—Sorting or classification of particles or molecules
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2200/00—Solutions for specific problems relating to chemical or physical laboratory apparatus
    • B01L2200/06—Fluid handling related problems
    • B01L2200/0647—Handling flowable solids, e.g. microscopic beads, cells, particles
    • B01L2200/0668—Trapping microscopic beads
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/08—Geometry, shape and general structure
    • B01L2300/0809—Geometry, shape and general structure rectangular shaped
    • B01L2300/0816—Cards, e.g. flat sample carriers usually with flow in two horizontal directions
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/08—Geometry, shape and general structure
    • B01L2300/0861—Configuration of multiple channels and/or chambers in a single devices
    • B01L2300/0864—Configuration of multiple channels and/or chambers in a single devices comprising only one inlet and multiple receiving wells, e.g. for separation, splitting
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/08—Geometry, shape and general structure
    • B01L2300/0861—Configuration of multiple channels and/or chambers in a single devices
    • B01L2300/0867—Multiple inlets and one sample wells, e.g. mixing, dilution
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2400/00—Moving or stopping fluids
    • B01L2400/04—Moving fluids with specific forces or mechanical means
    • B01L2400/0403—Moving fluids with specific forces or mechanical means specific forces
    • B01L2400/0415—Moving fluids with specific forces or mechanical means specific forces electrical forces, e.g. electrokinetic
    • B01L2400/0418—Moving fluids with specific forces or mechanical means specific forces electrical forces, e.g. electrokinetic electro-osmotic flow [EOF]
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2400/00—Moving or stopping fluids
    • B01L2400/04—Moving fluids with specific forces or mechanical means
    • B01L2400/0403—Moving fluids with specific forces or mechanical means specific forces
    • B01L2400/0433—Moving fluids with specific forces or mechanical means specific forces vibrational forces
    • B01L2400/0439—Moving fluids with specific forces or mechanical means specific forces vibrational forces ultrasonic vibrations, vibrating piezo elements
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2400/00—Moving or stopping fluids
    • B01L2400/04—Moving fluids with specific forces or mechanical means
    • B01L2400/0475—Moving fluids with specific forces or mechanical means specific mechanical means and fluid pressure
    • B01L2400/0487—Moving fluids with specific forces or mechanical means specific mechanical means and fluid pressure fluid pressure, pneumatics
    • B01L2400/049—Moving fluids with specific forces or mechanical means specific mechanical means and fluid pressure fluid pressure, pneumatics vacuum
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2400/00—Moving or stopping fluids
    • B01L2400/06—Valves, specific forms thereof
    • B01L2400/0622—Valves, specific forms thereof distribution valves, valves having multiple inlets and/or outlets, e.g. metering valves, multi-way valves
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
    • G01N15/10—Investigating individual particles
    • G01N15/14—Optical investigation techniques, e.g. flow cytometry
    • G01N15/1404—Handling flow, e.g. hydrodynamic focusing
    • G01N15/1409—Handling samples, e.g. injecting samples
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
    • G01N15/10—Investigating individual particles
    • G01N15/14—Optical investigation techniques, e.g. flow cytometry
    • G01N15/1484—Optical investigation techniques, e.g. flow cytometry microstructural devices

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Dispersion Chemistry (AREA)
  • Analytical Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Hematology (AREA)
  • Clinical Laboratory Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Physics & Mathematics (AREA)
  • Fluid Mechanics (AREA)
  • Automatic Analysis And Handling Materials Therefor (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
JP2010282167A 2010-12-17 2010-12-17 マイクロチップ及び微小粒子分取装置 Active JP5720233B2 (ja)

Priority Applications (3)

Application Number Priority Date Filing Date Title
JP2010282167A JP5720233B2 (ja) 2010-12-17 2010-12-17 マイクロチップ及び微小粒子分取装置
US13/315,052 US8487273B2 (en) 2010-12-17 2011-12-08 Microchip and particulate fractional collection apparatus
CN201110409903.1A CN102564925B (zh) 2010-12-17 2011-12-09 微芯片和微粒分取装置

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP2010282167A JP5720233B2 (ja) 2010-12-17 2010-12-17 マイクロチップ及び微小粒子分取装置

Publications (3)

Publication Number Publication Date
JP2012127922A JP2012127922A (ja) 2012-07-05
JP2012127922A5 JP2012127922A5 (OSRAM) 2013-12-19
JP5720233B2 true JP5720233B2 (ja) 2015-05-20

Family

ID=46233158

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2010282167A Active JP5720233B2 (ja) 2010-12-17 2010-12-17 マイクロチップ及び微小粒子分取装置

Country Status (2)

Country Link
US (1) US8487273B2 (OSRAM)
JP (1) JP5720233B2 (OSRAM)

Families Citing this family (47)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6808075B2 (en) 2002-04-17 2004-10-26 Cytonome, Inc. Method and apparatus for sorting particles
US6976590B2 (en) * 2002-06-24 2005-12-20 Cytonome, Inc. Method and apparatus for sorting particles
US9943847B2 (en) 2002-04-17 2018-04-17 Cytonome/St, Llc Microfluidic system including a bubble valve for regulating fluid flow through a microchannel
ZA200603614B (en) 2003-10-30 2007-09-26 Cytonome Inc Multilayer hydrodynamic sheath flow structure
US9260693B2 (en) 2004-12-03 2016-02-16 Cytonome/St, Llc Actuation of parallel microfluidic arrays
JP6172147B2 (ja) * 2012-07-18 2017-08-02 ソニー株式会社 微小粒子分取装置及び微小粒子分取方法
JP6036496B2 (ja) * 2012-07-24 2016-11-30 ソニー株式会社 微小粒子分取方法
JP5910412B2 (ja) 2012-08-16 2016-04-27 ソニー株式会社 微小粒子分取方法及び微小粒子分取用マイクロチップ
JP5480455B1 (ja) 2012-09-06 2014-04-23 古河電気工業株式会社 検体識別分取装置および検体識別分取方法
US9731293B2 (en) * 2012-10-03 2017-08-15 The United States Of America, As Represented By The Secretary Of The Navy Paired laser and electrokinetic separation, manipulation, and analysis device
CN105283753B (zh) 2013-03-14 2020-07-10 塞通诺米/St有限责任公司 流体动力聚焦设备和方法
JP6186812B2 (ja) * 2013-04-04 2017-08-30 ソニー株式会社 粒子分取装置及び粒子分取方法
CA2929275C (en) * 2013-10-30 2022-03-08 Premium Genetics (Uk) Ltd. Microfluidic system and method with focused energy apparatus
EP3151967A2 (en) * 2014-06-09 2017-04-12 Ascent Bio-Nano Technologies, Inc. System for manipulation and sorting of particles
CN105642173B (zh) * 2016-01-11 2018-09-14 中国科学院理化技术研究所 一种电渗微混合器
JP6953679B2 (ja) 2016-03-30 2021-10-27 ソニーグループ株式会社 試料分取キット、試料分取装置
BR112018074178A2 (pt) 2016-07-26 2019-03-06 Hewlett Packard Development Co aparelhos microfluídicos
JP6783153B2 (ja) * 2017-01-13 2020-11-11 アークレイ株式会社 フローセル及び測定装置
JP6919215B2 (ja) 2017-02-17 2021-08-18 ソニーグループ株式会社 マイクロチップ及び微小粒子分取装置
WO2018163943A1 (ja) 2017-03-08 2018-09-13 ソニー株式会社 細胞サンプル液送液用バッグ、細胞サンプル液送液方法、及び細胞サンプル液送液装置
EP3599456B1 (en) 2017-03-31 2025-06-11 Sony Group Corporation Channel unit and microparticle analysis device
JP7088177B2 (ja) * 2017-05-24 2022-06-21 ソニーグループ株式会社 微小粒子の吸引条件の最適化方法及び微小粒子分取装置
EP3633347B1 (en) 2017-05-26 2023-07-19 Sony Group Corporation Method for optimizing suction conditions for microparticles, and microparticle separation device
WO2019006190A1 (en) 2017-06-28 2019-01-03 Bio-Rad Laboratories, Inc. SYSTEM AND METHOD FOR DROPLELET DETECTION
JP6508265B2 (ja) * 2017-08-02 2019-05-08 ソニー株式会社 粒子分取装置及び粒子分取方法
WO2019089979A1 (en) 2017-11-01 2019-05-09 Bio-Rad Laboratories, Inc. Microfluidic system and method for arranging objects
WO2019167510A1 (ja) 2018-03-02 2019-09-06 ソニー株式会社 微小粒子の吸引条件の最適化方法、微小粒子分取用装置、微小粒子分取用システム及び微小粒子分取用プログラム
JP7059747B2 (ja) * 2018-03-27 2022-04-26 ソニーグループ株式会社 微小粒子分取方法、微小粒子分取用プログラム及び微小粒子分取用システム
JP2019190991A (ja) * 2018-04-25 2019-10-31 ソニー株式会社 微小粒子測定装置及び微小粒子測定方法
WO2019230489A1 (ja) * 2018-06-01 2019-12-05 ソニー株式会社 マイクロチップ及びサンプル分取キット
WO2020054735A1 (en) 2018-09-10 2020-03-19 Sony Corporation Microparticle sorting device, cell therapeutic agent manufacturing device, microparticle sorting method and program
JP7287399B2 (ja) 2018-09-10 2023-06-06 ソニーグループ株式会社 微小粒子分取用流路ユニット及び微小粒子分取装置
JP6791295B2 (ja) * 2019-04-04 2020-11-25 ソニー株式会社 粒子分取装置及び粒子分取方法
JP7312135B2 (ja) * 2019-04-08 2023-07-20 アークレイ株式会社 送液方法及び分析装置
JP7388131B2 (ja) * 2019-10-31 2023-11-29 ソニーグループ株式会社 微小粒子回収方法、微小粒子分取用マイクロチップ、微小粒子回収装置、エマルションの製造方法、及びエマルション
JP2021071441A (ja) 2019-11-01 2021-05-06 ソニー株式会社 チップ固定装置及び粒子検査装置
WO2021090555A1 (ja) 2019-11-05 2021-05-14 ソニー株式会社 微小粒子分取用マイクロチップのプライミング方法、微小粒子分取方法、微小粒子分取装置、及びプログラム
CN114616454A (zh) 2019-11-06 2022-06-10 索尼集团公司 光学测量设备和信息处理系统
WO2021090574A1 (ja) 2019-11-06 2021-05-14 ソニー株式会社 位置調整方法、微小粒子分析装置、及びプログラム
JP2021076455A (ja) 2019-11-07 2021-05-20 ソニー株式会社 分取制御装置、該分取制御装置を用いた粒子分取装置及び粒子分取システム、並びに分取制御方法、及び制御プログラム
US12436082B2 (en) 2019-11-20 2025-10-07 Sony Group Corporation Microchip, sample sorting kit, and microparticle sorting device
JP2022017705A (ja) 2020-07-14 2022-01-26 ソニーグループ株式会社 微小粒子分取装置、微小粒子分取方法、プログラム、及び微小粒子分取システム
JP2020190575A (ja) * 2020-08-25 2020-11-26 ソニー株式会社 粒子分取装置及び粒子分取方法
US12379304B2 (en) 2021-01-14 2025-08-05 Sony Group Corporation Particle analyzer, particle analysis method, and optical measurement device
JPWO2022201959A1 (OSRAM) 2021-03-26 2022-09-29
EP4317940A4 (en) 2021-03-31 2025-03-05 Sony Group Corporation Sample liquid accommodation container, sample liquid stirring device, microparticle sorting kit, and microparticle sorting device
WO2024071301A1 (ja) * 2022-09-29 2024-04-04 シンクサイト株式会社 マイクロ流路、及び測定装置

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH01170853A (ja) * 1987-12-25 1989-07-05 Hitachi Ltd 細胞選別装置
JP2001050887A (ja) * 1999-08-11 2001-02-23 Sysmex Corp 粒子分析装置
JP2003274924A (ja) 2002-03-26 2003-09-30 Kikuchi Jun 細胞分離方法及び装置
CA2480728A1 (en) * 2002-04-01 2003-10-16 Fluidigm Corporation Microfluidic particle-analysis systems
BR0309321A (pt) * 2002-04-17 2005-03-29 Cytonome Inc Método e aparelho para selecionar partìculas
CA2499245A1 (en) 2002-09-16 2004-03-25 Cytonome, Inc. Method and apparatus for sorting particles
JP4203548B2 (ja) 2002-09-23 2009-01-07 禅 高村 細胞分離方法、細胞分離装置および細胞分離装置の製造方法
WO2005108963A1 (en) * 2004-05-06 2005-11-17 Nanyang Technological University Microfluidic cell sorter system
US20070240495A1 (en) 2004-05-25 2007-10-18 Shuzo Hirahara Microfluidic Device and Analyzing/Sorting Apparatus Using The Same
JP4679847B2 (ja) 2004-07-12 2011-05-11 オリンパス株式会社 細胞の解析方法
JP2007330201A (ja) 2006-06-16 2007-12-27 Ab Size:Kk 細胞分取用マイクロチップ及び細胞分取方法
KR20080110167A (ko) * 2007-06-14 2008-12-18 삼성전자주식회사 시료 중의 입자를 집중화하고 검출하기 위한 장치 및 그를제조하는 방법
JP2010151777A (ja) * 2008-11-19 2010-07-08 Sony Corp 微小粒子解析装置、微小粒子解析用マイクロチップ及び微小粒子解析方法

Also Published As

Publication number Publication date
CN102564925A (zh) 2012-07-11
JP2012127922A (ja) 2012-07-05
US20120153185A1 (en) 2012-06-21
US8487273B2 (en) 2013-07-16

Similar Documents

Publication Publication Date Title
JP5720233B2 (ja) マイクロチップ及び微小粒子分取装置
JP7354368B2 (ja) マイクロ流体チャネルを使用してマイクロ粒子のバルク選別を行う方法及び装置
CN101609088B (zh) 微流控芯片和微流控芯片中的送流方法
KR101683066B1 (ko) 미소 입자 분취를 위한 장치 및 마이크로칩
US10315194B2 (en) Chip device and a particle analyzing apparatus
CN101644703B (zh) 微流控芯片、微粒分类装置以及流控方法
US9109197B2 (en) Device for concentrating and separating cells
JP6922281B2 (ja) マイクロチップ、及び微小粒子測定装置
CN108432132A (zh) 微流体颗粒操纵
JP2021181991A (ja) マイクロチップ及び微小粒子分取装置
US20220381670A1 (en) Sorting control device, particle sorting device and particle sorting system using sorting control device, sorting control method, and control program
JP5316530B2 (ja) マイクロチップとその流路構造
CN102564925B (zh) 微芯片和微粒分取装置
JP7287399B2 (ja) 微小粒子分取用流路ユニット及び微小粒子分取装置
JP4745755B2 (ja) 分画マイクロチップ及び分画装置
JP6965953B2 (ja) マイクロチップ及び微小粒子分析装置
US20240238786A1 (en) Droplet sortation

Legal Events

Date Code Title Description
A521 Request for written amendment filed

Free format text: JAPANESE INTERMEDIATE CODE: A523

Effective date: 20131105

A621 Written request for application examination

Free format text: JAPANESE INTERMEDIATE CODE: A621

Effective date: 20131105

A977 Report on retrieval

Free format text: JAPANESE INTERMEDIATE CODE: A971007

Effective date: 20140312

A131 Notification of reasons for refusal

Free format text: JAPANESE INTERMEDIATE CODE: A131

Effective date: 20141216

A521 Request for written amendment filed

Free format text: JAPANESE INTERMEDIATE CODE: A523

Effective date: 20150129

TRDD Decision of grant or rejection written
A01 Written decision to grant a patent or to grant a registration (utility model)

Free format text: JAPANESE INTERMEDIATE CODE: A01

Effective date: 20150224

A61 First payment of annual fees (during grant procedure)

Free format text: JAPANESE INTERMEDIATE CODE: A61

Effective date: 20150309

R151 Written notification of patent or utility model registration

Ref document number: 5720233

Country of ref document: JP

Free format text: JAPANESE INTERMEDIATE CODE: R151

R250 Receipt of annual fees

Free format text: JAPANESE INTERMEDIATE CODE: R250

R250 Receipt of annual fees

Free format text: JAPANESE INTERMEDIATE CODE: R250

R250 Receipt of annual fees

Free format text: JAPANESE INTERMEDIATE CODE: R250