JP5697448B2 - 膀胱癌の検出のための新規なマーカー - Google Patents

膀胱癌の検出のための新規なマーカー Download PDF

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JP5697448B2
JP5697448B2 JP2010524399A JP2010524399A JP5697448B2 JP 5697448 B2 JP5697448 B2 JP 5697448B2 JP 2010524399 A JP2010524399 A JP 2010524399A JP 2010524399 A JP2010524399 A JP 2010524399A JP 5697448 B2 JP5697448 B2 JP 5697448B2
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gene
bladder cancer
nid2
sample
twist1
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JP2010538624A5 (https=
JP2010538624A (ja
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イザベル レナール，
イザベル レナール，
クリエキンジェ， ウィム ファン
クリエキンジェ， ウィム ファン
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エムディーエックスヘルス エスエー
エムディーエックスヘルス エスエー
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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • C12Q1/6886—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material for cancer
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/106—Pharmacogenomics, i.e. genetic variability in individual responses to drugs and drug metabolism
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/112—Disease subtyping, staging or classification
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/154—Methylation markers

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  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Engineering & Computer Science (AREA)
  • Analytical Chemistry (AREA)
  • Wood Science & Technology (AREA)
  • Pathology (AREA)
  • Genetics & Genomics (AREA)
  • Immunology (AREA)
  • Zoology (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Hospice & Palliative Care (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Physics & Mathematics (AREA)
  • Oncology (AREA)
  • Medicinal Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
JP2010524399A 2007-09-17 2008-09-11 膀胱癌の検出のための新規なマーカー Active JP5697448B2 (ja)

Applications Claiming Priority (7)

Application Number Priority Date Filing Date Title
US96012907P 2007-09-17 2007-09-17
US60/960,129 2007-09-17
US7197108P 2008-05-28 2008-05-28
US61/071,971 2008-05-28
GBPCT/GB2008/002093 2008-06-19
PCT/GB2008/002093 WO2008155549A2 (en) 2007-06-19 2008-06-19 Improved urine sample collecting and processing
PCT/EP2008/007465 WO2009036922A2 (en) 2007-09-17 2008-09-11 Novel markers for bladder cancer detection

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2014208231A Division JP2015051006A (ja) 2007-09-17 2014-10-09 膀胱癌の検出のための新規なマーカー

Publications (3)

Publication Number Publication Date
JP2010538624A JP2010538624A (ja) 2010-12-16
JP2010538624A5 JP2010538624A5 (https=) 2011-11-04
JP5697448B2 true JP5697448B2 (ja) 2015-04-08

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JP2010524399A Active JP5697448B2 (ja) 2007-09-17 2008-09-11 膀胱癌の検出のための新規なマーカー
JP2014208231A Pending JP2015051006A (ja) 2007-09-17 2014-10-09 膀胱癌の検出のための新規なマーカー

Family Applications After (1)

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JP2014208231A Pending JP2015051006A (ja) 2007-09-17 2014-10-09 膀胱癌の検出のための新規なマーカー

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US (2) US9322065B2 (https=)
EP (2) EP2198042B1 (https=)
JP (2) JP5697448B2 (https=)
CA (1) CA2699606C (https=)
DK (1) DK2198042T3 (https=)
ES (1) ES2605237T3 (https=)
PL (1) PL2198042T3 (https=)
WO (1) WO2009036922A2 (https=)

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* Cited by examiner, † Cited by third party
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JP2015051006A (ja) * 2007-09-17 2015-03-19 エムディーエックスヘルス エスエー 膀胱癌の検出のための新規なマーカー

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CA2755358A1 (en) 2009-03-13 2010-09-16 Mdxhealth Sa Novel markers for bladder cancer detection
WO2010113529A1 (ja) * 2009-04-03 2010-10-07 国立大学法人山口大学 大腸腫瘍の検出方法
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US9783850B2 (en) 2010-02-19 2017-10-10 Nucleix Identification of source of DNA samples
WO2011104731A1 (en) * 2010-02-26 2011-09-01 Decode Genetics Ehf Genetic variants as markers for use in urinary bladder cancer risk assessment, diagnosis, prognosis and treatment
US9328379B2 (en) * 2010-03-12 2016-05-03 The Johns Hopkins University Hypermethylation biomarkers for detection of head and neck squamous cell cancer
US20130041047A1 (en) * 2011-06-01 2013-02-14 Aros Applied Biotechnology As Urinary Methylation Markers for Bladder Cancer
US10323285B2 (en) 2013-09-09 2019-06-18 Nantomics, Llc Proteomics analysis and discovery through DNA and RNA sequencing, systems and methods
US10689652B2 (en) 2013-10-02 2020-06-23 The Regents Of The University Of California Methods for immortalization of epithelial cells
US9476100B1 (en) 2015-07-06 2016-10-25 Nucleix Ltd. Methods for diagnosing bladder cancer
DE102015009187B3 (de) 2015-07-16 2016-10-13 Dimo Dietrich Verfahren zur Bestimmung einer Mutation in genomischer DNA, Verwendung des Verfahrens und Kit zur Durchführung des Verfahrens
WO2017062517A1 (en) * 2015-10-06 2017-04-13 The Regents Of The University Of California Non-coding rnas linked to immortality and associated methods and compositions
WO2017062989A1 (en) * 2015-10-08 2017-04-13 Urology Diagnostics, Inc. Diagnostic assay for urine monitoring of bladder cancer
RU2612139C1 (ru) * 2015-12-29 2017-03-02 Федеральное государственное бюджетное учреждение науки институт биоорганической химии им. академиков М.М. Шемякина и Ю.А. Овчинникова Российской академии наук (ИБХ РАН) Набор синтетических олигонуклеотидов для определения уровней экспрессии гена pdlim4
WO2017171548A1 (en) 2016-04-01 2017-10-05 Nanomed Diagnostics B.V. Detection of cancer in urine
EP3481965A4 (en) 2016-07-06 2020-03-18 Case Western Reserve University METHOD AND COMPOSITIONS FOR DETECTING NEOPLASIA OF THE EYES AND / OR METAPLASIA OF THE EYES
WO2018047883A1 (ja) * 2016-09-06 2018-03-15 株式会社ユカシカド スポット尿を用いたヘルスケアシステム
KR20190054086A (ko) * 2016-09-29 2019-05-21 이에이 파마 가부시키가이샤 고발성 대장암 발증 가능성의 판정 방법
CN107014658B (zh) * 2017-05-27 2023-08-25 四川省肿瘤医院 提取游离细胞的方法及试剂盒
PL3662080T3 (pl) * 2017-08-02 2022-04-19 Sarstedt Ag & Co. Kg Sposób i formulacja do stabilizacji bezkomórkowych kwasów nukleinowych i komórek
JP2021530214A (ja) * 2018-07-11 2021-11-11 スティヒティング フェーユーエムセー 膀胱がんのための尿ｄｎａメチル化マーカー
IL265451B (en) 2019-03-18 2020-01-30 Frumkin Dan Methods and systems for the detection of methylation changes in DNA samples
KR102186534B1 (ko) * 2019-04-11 2020-12-03 차의과학대학교 산학협력단 수지상세포의 성숙도 측정 방법 및 조성물, 그리고 이의 용도
CN110283914A (zh) * 2019-07-29 2019-09-27 上海透景生命科技股份有限公司 一种膀胱癌的新型基因诊断试剂盒及其应用
CN113943799B (zh) * 2020-07-16 2023-12-15 广州达健生物科技有限公司 用于检测膀胱癌的组合物及其试剂盒和应用
CN113957160B (zh) * 2020-07-20 2024-03-29 深圳华大生命科学研究院 检测膀胱癌的标志物及检测该标志物的引物对及其应用
CN115094139B (zh) * 2022-06-22 2023-04-28 武汉艾米森生命科技有限公司 检测甲基化水平的试剂在制备膀胱癌诊断产品中的应用以及膀胱癌诊断试剂盒
CN116004831B (zh) * 2023-01-05 2024-10-01 武汉艾米森生命科技有限公司 一种用于膀胱癌的诊断或辅助诊断的试剂及检测试剂盒
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CN117265114A (zh) * 2023-10-13 2023-12-22 青岛瑞思德医学检验实验室有限公司 一种膀胱癌检测试剂盒及检测方法
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* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2015051006A (ja) * 2007-09-17 2015-03-19 エムディーエックスヘルス エスエー 膀胱癌の検出のための新規なマーカー

Also Published As

Publication number Publication date
US20100280134A1 (en) 2010-11-04
WO2009036922A2 (en) 2009-03-26
US10113202B2 (en) 2018-10-30
EP2198042B1 (en) 2016-11-02
CA2699606C (en) 2023-04-11
PL2198042T3 (pl) 2017-05-31
EP2198042A2 (en) 2010-06-23
JP2010538624A (ja) 2010-12-16
JP2015051006A (ja) 2015-03-19
ES2605237T3 (es) 2017-03-13
US9322065B2 (en) 2016-04-26
CA2699606A1 (en) 2009-03-26
DK2198042T3 (en) 2017-01-23
WO2009036922A3 (en) 2009-05-28
US20160208341A1 (en) 2016-07-21
EP3147375A1 (en) 2017-03-29

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