PL2198042T3 - Nowe markery do wykrywania raka pęcherza moczowego - Google Patents
Nowe markery do wykrywania raka pęcherza moczowegoInfo
- Publication number
- PL2198042T3 PL2198042T3 PL08802026T PL08802026T PL2198042T3 PL 2198042 T3 PL2198042 T3 PL 2198042T3 PL 08802026 T PL08802026 T PL 08802026T PL 08802026 T PL08802026 T PL 08802026T PL 2198042 T3 PL2198042 T3 PL 2198042T3
- Authority
- PL
- Poland
- Prior art keywords
- bladder cancer
- cancer detection
- novel markers
- markers
- novel
- Prior art date
Links
- 206010005003 Bladder cancer Diseases 0.000 title 1
- 208000007097 Urinary Bladder Neoplasms Diseases 0.000 title 1
- 238000001514 detection method Methods 0.000 title 1
- 201000005112 urinary bladder cancer Diseases 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
- C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
- C12Q1/6886—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material for cancer
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/106—Pharmacogenomics, i.e. genetic variability in individual responses to drugs and drug metabolism
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/112—Disease subtyping, staging or classification
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/154—Methylation markers
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Engineering & Computer Science (AREA)
- Analytical Chemistry (AREA)
- Wood Science & Technology (AREA)
- Pathology (AREA)
- Genetics & Genomics (AREA)
- Immunology (AREA)
- Zoology (AREA)
- General Health & Medical Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Engineering & Computer Science (AREA)
- Molecular Biology (AREA)
- Hospice & Palliative Care (AREA)
- Microbiology (AREA)
- Biotechnology (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Physics & Mathematics (AREA)
- Oncology (AREA)
- Medicinal Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Apparatus Associated With Microorganisms And Enzymes (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US96012907P | 2007-09-17 | 2007-09-17 | |
| US7197108P | 2008-05-28 | 2008-05-28 | |
| PCT/GB2008/002093 WO2008155549A2 (en) | 2007-06-19 | 2008-06-19 | Improved urine sample collecting and processing |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PL2198042T3 true PL2198042T3 (pl) | 2017-05-31 |
Family
ID=39945563
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PL08802026T PL2198042T3 (pl) | 2007-09-17 | 2008-09-11 | Nowe markery do wykrywania raka pęcherza moczowego |
Country Status (8)
| Country | Link |
|---|---|
| US (2) | US9322065B2 (https=) |
| EP (2) | EP2198042B1 (https=) |
| JP (2) | JP5697448B2 (https=) |
| CA (1) | CA2699606C (https=) |
| DK (1) | DK2198042T3 (https=) |
| ES (1) | ES2605237T3 (https=) |
| PL (1) | PL2198042T3 (https=) |
| WO (1) | WO2009036922A2 (https=) |
Families Citing this family (35)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101353695B (zh) * | 2007-07-23 | 2013-05-01 | 上海市肿瘤研究所 | 尿沉淀dna甲基化谱式分析诊断膀胱癌的方法和试剂盒 |
| US9322065B2 (en) * | 2007-09-17 | 2016-04-26 | Mdxhealth Sa | Methods for determining methylation of the TWIST1 gene for bladder cancer detection |
| CA2755358A1 (en) | 2009-03-13 | 2010-09-16 | Mdxhealth Sa | Novel markers for bladder cancer detection |
| WO2010113529A1 (ja) * | 2009-04-03 | 2010-10-07 | 国立大学法人山口大学 | 大腸腫瘍の検出方法 |
| EP3048176B1 (en) | 2009-04-20 | 2019-03-06 | Erasmus University Medical Center Rotterdam | Method of diagnosing bladder cancer |
| ES2669439T3 (es) * | 2009-06-26 | 2018-05-25 | Epigenomics Ag | Métodos y ácidos nucleicos para el análisis del carcinoma de vejiga |
| US9752187B2 (en) | 2009-12-11 | 2017-09-05 | Nucleix | Categorization of DNA samples |
| US9783850B2 (en) | 2010-02-19 | 2017-10-10 | Nucleix | Identification of source of DNA samples |
| WO2011104731A1 (en) * | 2010-02-26 | 2011-09-01 | Decode Genetics Ehf | Genetic variants as markers for use in urinary bladder cancer risk assessment, diagnosis, prognosis and treatment |
| US9328379B2 (en) * | 2010-03-12 | 2016-05-03 | The Johns Hopkins University | Hypermethylation biomarkers for detection of head and neck squamous cell cancer |
| US20130041047A1 (en) * | 2011-06-01 | 2013-02-14 | Aros Applied Biotechnology As | Urinary Methylation Markers for Bladder Cancer |
| US10323285B2 (en) | 2013-09-09 | 2019-06-18 | Nantomics, Llc | Proteomics analysis and discovery through DNA and RNA sequencing, systems and methods |
| US10689652B2 (en) | 2013-10-02 | 2020-06-23 | The Regents Of The University Of California | Methods for immortalization of epithelial cells |
| US9476100B1 (en) | 2015-07-06 | 2016-10-25 | Nucleix Ltd. | Methods for diagnosing bladder cancer |
| DE102015009187B3 (de) | 2015-07-16 | 2016-10-13 | Dimo Dietrich | Verfahren zur Bestimmung einer Mutation in genomischer DNA, Verwendung des Verfahrens und Kit zur Durchführung des Verfahrens |
| WO2017062517A1 (en) * | 2015-10-06 | 2017-04-13 | The Regents Of The University Of California | Non-coding rnas linked to immortality and associated methods and compositions |
| WO2017062989A1 (en) * | 2015-10-08 | 2017-04-13 | Urology Diagnostics, Inc. | Diagnostic assay for urine monitoring of bladder cancer |
| RU2612139C1 (ru) * | 2015-12-29 | 2017-03-02 | Федеральное государственное бюджетное учреждение науки институт биоорганической химии им. академиков М.М. Шемякина и Ю.А. Овчинникова Российской академии наук (ИБХ РАН) | Набор синтетических олигонуклеотидов для определения уровней экспрессии гена pdlim4 |
| WO2017171548A1 (en) | 2016-04-01 | 2017-10-05 | Nanomed Diagnostics B.V. | Detection of cancer in urine |
| EP3481965A4 (en) | 2016-07-06 | 2020-03-18 | Case Western Reserve University | METHOD AND COMPOSITIONS FOR DETECTING NEOPLASIA OF THE EYES AND / OR METAPLASIA OF THE EYES |
| WO2018047883A1 (ja) * | 2016-09-06 | 2018-03-15 | 株式会社ユカシカド | スポット尿を用いたヘルスケアシステム |
| KR20190054086A (ko) * | 2016-09-29 | 2019-05-21 | 이에이 파마 가부시키가이샤 | 고발성 대장암 발증 가능성의 판정 방법 |
| CN107014658B (zh) * | 2017-05-27 | 2023-08-25 | 四川省肿瘤医院 | 提取游离细胞的方法及试剂盒 |
| PL3662080T3 (pl) * | 2017-08-02 | 2022-04-19 | Sarstedt Ag & Co. Kg | Sposób i formulacja do stabilizacji bezkomórkowych kwasów nukleinowych i komórek |
| JP2021530214A (ja) * | 2018-07-11 | 2021-11-11 | スティヒティング フェーユーエムセー | 膀胱がんのための尿ｄｎａメチル化マーカー |
| IL265451B (en) | 2019-03-18 | 2020-01-30 | Frumkin Dan | Methods and systems for the detection of methylation changes in DNA samples |
| KR102186534B1 (ko) * | 2019-04-11 | 2020-12-03 | 차의과학대학교 산학협력단 | 수지상세포의 성숙도 측정 방법 및 조성물, 그리고 이의 용도 |
| CN110283914A (zh) * | 2019-07-29 | 2019-09-27 | 上海透景生命科技股份有限公司 | 一种膀胱癌的新型基因诊断试剂盒及其应用 |
| CN113943799B (zh) * | 2020-07-16 | 2023-12-15 | 广州达健生物科技有限公司 | 用于检测膀胱癌的组合物及其试剂盒和应用 |
| CN113957160B (zh) * | 2020-07-20 | 2024-03-29 | 深圳华大生命科学研究院 | 检测膀胱癌的标志物及检测该标志物的引物对及其应用 |
| CN115094139B (zh) * | 2022-06-22 | 2023-04-28 | 武汉艾米森生命科技有限公司 | 检测甲基化水平的试剂在制备膀胱癌诊断产品中的应用以及膀胱癌诊断试剂盒 |
| CN116004831B (zh) * | 2023-01-05 | 2024-10-01 | 武汉艾米森生命科技有限公司 | 一种用于膀胱癌的诊断或辅助诊断的试剂及检测试剂盒 |
| IL321198A (en) * | 2023-01-20 | 2025-07-01 | Grail Inc | Methods for analysis of cell-free nucleic acids in urine |
| CN117265114A (zh) * | 2023-10-13 | 2023-12-22 | 青岛瑞思德医学检验实验室有限公司 | 一种膀胱癌检测试剂盒及检测方法 |
| CN119331973A (zh) * | 2024-10-17 | 2025-01-21 | 南京科佰生物科技有限公司 | Twist1基因甲基化检测引物探针体系及其试剂盒 |
Family Cites Families (19)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4437975A (en) | 1977-07-20 | 1984-03-20 | Mobil Oil Corporation | Manufacture of lube base stock oil |
| CA1340843C (en) | 1987-07-31 | 1999-12-07 | J. Lawrence Burg | Selective amplification of target polynucleotide sequences |
| CA2005589C (en) | 1988-12-16 | 2001-02-06 | Akzo Nobel Nv | Self-sustained, sequence replication system |
| US6017704A (en) | 1996-06-03 | 2000-01-25 | The Johns Hopkins University School Of Medicine | Method of detection of methylated nucleic acid using agents which modify unmethylated cytosine and distinguishing modified methylated and non-methylated nucleic acids |
| GB9710995D0 (en) * | 1997-05-28 | 1997-07-23 | Marie Curie Research Inst | Tumour suppressor locus and gene at 9q32-33 |
| ATE275956T1 (de) * | 1998-10-19 | 2004-10-15 | Methylgene Inc | Veränderung der dns methyltransferase durch kombinationstherapie |
| KR100475649B1 (ko) * | 2001-01-29 | 2005-03-10 | 배석철 | 항암활성을 나타내는 ｒｕｎｘ３ 유전자 및 그의 용도 |
| JP2005535283A (ja) | 2001-11-13 | 2005-11-24 | ルビコン ゲノミクス インコーポレイテッド | ランダムフラグメント化により生成されたｄｎａ分子を用いたｄｎａ増幅および配列決定 |
| WO2004067726A2 (en) | 2003-01-29 | 2004-08-12 | Keck Graduate Institute | Isothermal reactions for the amplification of oligonucleotides |
| US20040209299A1 (en) | 2003-03-07 | 2004-10-21 | Rubicon Genomics, Inc. | In vitro DNA immortalization and whole genome amplification using libraries generated from randomly fragmented DNA |
| EP1604040B1 (en) | 2003-03-07 | 2010-10-13 | Rubicon Genomics, Inc. | Amplification and analysis of whole genome and whole transcriptome libraries generated by a dna polymerization process |
| WO2005042713A2 (en) * | 2003-10-28 | 2005-05-12 | The Johns Hopkins University | Quantitative multiplex methylation-specific pcr |
| JP4590893B2 (ja) | 2004-03-23 | 2010-12-01 | Ｊｓｒ株式会社 | 接着剤用液状硬化性樹脂組成物 |
| ES2446250T3 (es) * | 2005-05-02 | 2014-03-06 | University Of Southern California | Marcadores de metilación del ADN asociados con el fenotipo metilador de islas CpG (CIMP) en el cáncer colorrectal humano |
| WO2006135886A2 (en) | 2005-06-13 | 2006-12-21 | The Regents Of The University Of Michigan | Compositions and methods for treating and diagnosing cancer |
| CN101365806B (zh) * | 2005-12-01 | 2016-11-16 | 医学预后研究所 | 用于鉴定治疗反应的生物标记的方法和装置及其预测疗效的用途 |
| WO2007116417A1 (en) * | 2006-04-07 | 2007-10-18 | Silvia Sabbioni | Novel dna methylation markers useful for the diagnosis of neoplastic diseases |
| WO2008155549A2 (en) * | 2007-06-19 | 2008-12-24 | Oncomethylome Sciences Sa | Improved urine sample collecting and processing |
| US9322065B2 (en) * | 2007-09-17 | 2016-04-26 | Mdxhealth Sa | Methods for determining methylation of the TWIST1 gene for bladder cancer detection |
-
2008
- 2008-09-11 US US12/678,696 patent/US9322065B2/en active Active
- 2008-09-11 CA CA2699606A patent/CA2699606C/en active Active
- 2008-09-11 PL PL08802026T patent/PL2198042T3/pl unknown
- 2008-09-11 EP EP08802026.8A patent/EP2198042B1/en active Active
- 2008-09-11 WO PCT/EP2008/007465 patent/WO2009036922A2/en not_active Ceased
- 2008-09-11 JP JP2010524399A patent/JP5697448B2/ja active Active
- 2008-09-11 EP EP16196638.7A patent/EP3147375A1/en not_active Withdrawn
- 2008-09-11 DK DK08802026.8T patent/DK2198042T3/en active
- 2008-09-11 ES ES08802026.8T patent/ES2605237T3/es active Active
-
2014
- 2014-10-09 JP JP2014208231A patent/JP2015051006A/ja active Pending
-
2016
- 2016-03-24 US US15/079,948 patent/US10113202B2/en active Active
Also Published As
| Publication number | Publication date |
|---|---|
| US20100280134A1 (en) | 2010-11-04 |
| WO2009036922A2 (en) | 2009-03-26 |
| US10113202B2 (en) | 2018-10-30 |
| EP2198042B1 (en) | 2016-11-02 |
| CA2699606C (en) | 2023-04-11 |
| EP2198042A2 (en) | 2010-06-23 |
| JP5697448B2 (ja) | 2015-04-08 |
| JP2010538624A (ja) | 2010-12-16 |
| JP2015051006A (ja) | 2015-03-19 |
| ES2605237T3 (es) | 2017-03-13 |
| US9322065B2 (en) | 2016-04-26 |
| CA2699606A1 (en) | 2009-03-26 |
| DK2198042T3 (en) | 2017-01-23 |
| WO2009036922A3 (en) | 2009-05-28 |
| US20160208341A1 (en) | 2016-07-21 |
| EP3147375A1 (en) | 2017-03-29 |
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