JP2010538624A5 - - Google Patents
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- JP2010538624A5 JP2010538624A5 JP2010524399A JP2010524399A JP2010538624A5 JP 2010538624 A5 JP2010538624 A5 JP 2010538624A5 JP 2010524399 A JP2010524399 A JP 2010524399A JP 2010524399 A JP2010524399 A JP 2010524399A JP 2010538624 A5 JP2010538624 A5 JP 2010538624A5
- Authority
- JP
- Japan
- Prior art keywords
- seq
- nid2
- twist1
- detecting
- runx3
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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Applications Claiming Priority (7)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US96012907P | 2007-09-17 | 2007-09-17 | |
| US60/960,129 | 2007-09-17 | ||
| US7197108P | 2008-05-28 | 2008-05-28 | |
| US61/071,971 | 2008-05-28 | ||
| GBPCT/GB2008/002093 | 2008-06-19 | ||
| PCT/GB2008/002093 WO2008155549A2 (en) | 2007-06-19 | 2008-06-19 | Improved urine sample collecting and processing |
| PCT/EP2008/007465 WO2009036922A2 (en) | 2007-09-17 | 2008-09-11 | Novel markers for bladder cancer detection |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2014208231A Division JP2015051006A (ja) | 2007-09-17 | 2014-10-09 | 膀胱癌の検出のための新規なマーカー |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2010538624A JP2010538624A (ja) | 2010-12-16 |
| JP2010538624A5 true JP2010538624A5 (https=) | 2011-11-04 |
| JP5697448B2 JP5697448B2 (ja) | 2015-04-08 |
Family
ID=39945563
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2010524399A Active JP5697448B2 (ja) | 2007-09-17 | 2008-09-11 | 膀胱癌の検出のための新規なマーカー |
| JP2014208231A Pending JP2015051006A (ja) | 2007-09-17 | 2014-10-09 | 膀胱癌の検出のための新規なマーカー |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2014208231A Pending JP2015051006A (ja) | 2007-09-17 | 2014-10-09 | 膀胱癌の検出のための新規なマーカー |
Country Status (8)
| Country | Link |
|---|---|
| US (2) | US9322065B2 (https=) |
| EP (2) | EP2198042B1 (https=) |
| JP (2) | JP5697448B2 (https=) |
| CA (1) | CA2699606C (https=) |
| DK (1) | DK2198042T3 (https=) |
| ES (1) | ES2605237T3 (https=) |
| PL (1) | PL2198042T3 (https=) |
| WO (1) | WO2009036922A2 (https=) |
Families Citing this family (35)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101353695B (zh) * | 2007-07-23 | 2013-05-01 | 上海市肿瘤研究所 | 尿沉淀dna甲基化谱式分析诊断膀胱癌的方法和试剂盒 |
| US9322065B2 (en) * | 2007-09-17 | 2016-04-26 | Mdxhealth Sa | Methods for determining methylation of the TWIST1 gene for bladder cancer detection |
| CA2755358A1 (en) | 2009-03-13 | 2010-09-16 | Mdxhealth Sa | Novel markers for bladder cancer detection |
| WO2010113529A1 (ja) * | 2009-04-03 | 2010-10-07 | 国立大学法人山口大学 | 大腸腫瘍の検出方法 |
| EP3048176B1 (en) | 2009-04-20 | 2019-03-06 | Erasmus University Medical Center Rotterdam | Method of diagnosing bladder cancer |
| ES2669439T3 (es) * | 2009-06-26 | 2018-05-25 | Epigenomics Ag | Métodos y ácidos nucleicos para el análisis del carcinoma de vejiga |
| US9752187B2 (en) | 2009-12-11 | 2017-09-05 | Nucleix | Categorization of DNA samples |
| US9783850B2 (en) | 2010-02-19 | 2017-10-10 | Nucleix | Identification of source of DNA samples |
| WO2011104731A1 (en) * | 2010-02-26 | 2011-09-01 | Decode Genetics Ehf | Genetic variants as markers for use in urinary bladder cancer risk assessment, diagnosis, prognosis and treatment |
| US9328379B2 (en) * | 2010-03-12 | 2016-05-03 | The Johns Hopkins University | Hypermethylation biomarkers for detection of head and neck squamous cell cancer |
| US20130041047A1 (en) * | 2011-06-01 | 2013-02-14 | Aros Applied Biotechnology As | Urinary Methylation Markers for Bladder Cancer |
| US10323285B2 (en) | 2013-09-09 | 2019-06-18 | Nantomics, Llc | Proteomics analysis and discovery through DNA and RNA sequencing, systems and methods |
| US10689652B2 (en) | 2013-10-02 | 2020-06-23 | The Regents Of The University Of California | Methods for immortalization of epithelial cells |
| US9476100B1 (en) | 2015-07-06 | 2016-10-25 | Nucleix Ltd. | Methods for diagnosing bladder cancer |
| DE102015009187B3 (de) | 2015-07-16 | 2016-10-13 | Dimo Dietrich | Verfahren zur Bestimmung einer Mutation in genomischer DNA, Verwendung des Verfahrens und Kit zur Durchführung des Verfahrens |
| WO2017062517A1 (en) * | 2015-10-06 | 2017-04-13 | The Regents Of The University Of California | Non-coding rnas linked to immortality and associated methods and compositions |
| WO2017062989A1 (en) * | 2015-10-08 | 2017-04-13 | Urology Diagnostics, Inc. | Diagnostic assay for urine monitoring of bladder cancer |
| RU2612139C1 (ru) * | 2015-12-29 | 2017-03-02 | Федеральное государственное бюджетное учреждение науки институт биоорганической химии им. академиков М.М. Шемякина и Ю.А. Овчинникова Российской академии наук (ИБХ РАН) | Набор синтетических олигонуклеотидов для определения уровней экспрессии гена pdlim4 |
| WO2017171548A1 (en) | 2016-04-01 | 2017-10-05 | Nanomed Diagnostics B.V. | Detection of cancer in urine |
| EP3481965A4 (en) | 2016-07-06 | 2020-03-18 | Case Western Reserve University | METHOD AND COMPOSITIONS FOR DETECTING NEOPLASIA OF THE EYES AND / OR METAPLASIA OF THE EYES |
| WO2018047883A1 (ja) * | 2016-09-06 | 2018-03-15 | 株式会社ユカシカド | スポット尿を用いたヘルスケアシステム |
| KR20190054086A (ko) * | 2016-09-29 | 2019-05-21 | 이에이 파마 가부시키가이샤 | 고발성 대장암 발증 가능성의 판정 방법 |
| CN107014658B (zh) * | 2017-05-27 | 2023-08-25 | 四川省肿瘤医院 | 提取游离细胞的方法及试剂盒 |
| PL3662080T3 (pl) * | 2017-08-02 | 2022-04-19 | Sarstedt Ag & Co. Kg | Sposób i formulacja do stabilizacji bezkomórkowych kwasów nukleinowych i komórek |
| JP2021530214A (ja) * | 2018-07-11 | 2021-11-11 | スティヒティング フェーユーエムセー | 膀胱がんのための尿ｄｎａメチル化マーカー |
| IL265451B (en) | 2019-03-18 | 2020-01-30 | Frumkin Dan | Methods and systems for the detection of methylation changes in DNA samples |
| KR102186534B1 (ko) * | 2019-04-11 | 2020-12-03 | 차의과학대학교 산학협력단 | 수지상세포의 성숙도 측정 방법 및 조성물, 그리고 이의 용도 |
| CN110283914A (zh) * | 2019-07-29 | 2019-09-27 | 上海透景生命科技股份有限公司 | 一种膀胱癌的新型基因诊断试剂盒及其应用 |
| CN113943799B (zh) * | 2020-07-16 | 2023-12-15 | 广州达健生物科技有限公司 | 用于检测膀胱癌的组合物及其试剂盒和应用 |
| CN113957160B (zh) * | 2020-07-20 | 2024-03-29 | 深圳华大生命科学研究院 | 检测膀胱癌的标志物及检测该标志物的引物对及其应用 |
| CN115094139B (zh) * | 2022-06-22 | 2023-04-28 | 武汉艾米森生命科技有限公司 | 检测甲基化水平的试剂在制备膀胱癌诊断产品中的应用以及膀胱癌诊断试剂盒 |
| CN116004831B (zh) * | 2023-01-05 | 2024-10-01 | 武汉艾米森生命科技有限公司 | 一种用于膀胱癌的诊断或辅助诊断的试剂及检测试剂盒 |
| IL321198A (en) * | 2023-01-20 | 2025-07-01 | Grail Inc | Methods for analysis of cell-free nucleic acids in urine |
| CN117265114A (zh) * | 2023-10-13 | 2023-12-22 | 青岛瑞思德医学检验实验室有限公司 | 一种膀胱癌检测试剂盒及检测方法 |
| CN119331973A (zh) * | 2024-10-17 | 2025-01-21 | 南京科佰生物科技有限公司 | Twist1基因甲基化检测引物探针体系及其试剂盒 |
Family Cites Families (19)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4437975A (en) | 1977-07-20 | 1984-03-20 | Mobil Oil Corporation | Manufacture of lube base stock oil |
| CA1340843C (en) | 1987-07-31 | 1999-12-07 | J. Lawrence Burg | Selective amplification of target polynucleotide sequences |
| CA2005589C (en) | 1988-12-16 | 2001-02-06 | Akzo Nobel Nv | Self-sustained, sequence replication system |
| US6017704A (en) | 1996-06-03 | 2000-01-25 | The Johns Hopkins University School Of Medicine | Method of detection of methylated nucleic acid using agents which modify unmethylated cytosine and distinguishing modified methylated and non-methylated nucleic acids |
| GB9710995D0 (en) * | 1997-05-28 | 1997-07-23 | Marie Curie Research Inst | Tumour suppressor locus and gene at 9q32-33 |
| ATE275956T1 (de) * | 1998-10-19 | 2004-10-15 | Methylgene Inc | Veränderung der dns methyltransferase durch kombinationstherapie |
| KR100475649B1 (ko) * | 2001-01-29 | 2005-03-10 | 배석철 | 항암활성을 나타내는 ｒｕｎｘ３ 유전자 및 그의 용도 |
| JP2005535283A (ja) | 2001-11-13 | 2005-11-24 | ルビコン ゲノミクス インコーポレイテッド | ランダムフラグメント化により生成されたｄｎａ分子を用いたｄｎａ増幅および配列決定 |
| WO2004067726A2 (en) | 2003-01-29 | 2004-08-12 | Keck Graduate Institute | Isothermal reactions for the amplification of oligonucleotides |
| US20040209299A1 (en) | 2003-03-07 | 2004-10-21 | Rubicon Genomics, Inc. | In vitro DNA immortalization and whole genome amplification using libraries generated from randomly fragmented DNA |
| EP1604040B1 (en) | 2003-03-07 | 2010-10-13 | Rubicon Genomics, Inc. | Amplification and analysis of whole genome and whole transcriptome libraries generated by a dna polymerization process |
| WO2005042713A2 (en) * | 2003-10-28 | 2005-05-12 | The Johns Hopkins University | Quantitative multiplex methylation-specific pcr |
| JP4590893B2 (ja) | 2004-03-23 | 2010-12-01 | Ｊｓｒ株式会社 | 接着剤用液状硬化性樹脂組成物 |
| ES2446250T3 (es) * | 2005-05-02 | 2014-03-06 | University Of Southern California | Marcadores de metilación del ADN asociados con el fenotipo metilador de islas CpG (CIMP) en el cáncer colorrectal humano |
| WO2006135886A2 (en) | 2005-06-13 | 2006-12-21 | The Regents Of The University Of Michigan | Compositions and methods for treating and diagnosing cancer |
| CN101365806B (zh) * | 2005-12-01 | 2016-11-16 | 医学预后研究所 | 用于鉴定治疗反应的生物标记的方法和装置及其预测疗效的用途 |
| WO2007116417A1 (en) * | 2006-04-07 | 2007-10-18 | Silvia Sabbioni | Novel dna methylation markers useful for the diagnosis of neoplastic diseases |
| WO2008155549A2 (en) * | 2007-06-19 | 2008-12-24 | Oncomethylome Sciences Sa | Improved urine sample collecting and processing |
| US9322065B2 (en) * | 2007-09-17 | 2016-04-26 | Mdxhealth Sa | Methods for determining methylation of the TWIST1 gene for bladder cancer detection |
-
2008
- 2008-09-11 US US12/678,696 patent/US9322065B2/en active Active
- 2008-09-11 CA CA2699606A patent/CA2699606C/en active Active
- 2008-09-11 PL PL08802026T patent/PL2198042T3/pl unknown
- 2008-09-11 EP EP08802026.8A patent/EP2198042B1/en active Active
- 2008-09-11 WO PCT/EP2008/007465 patent/WO2009036922A2/en not_active Ceased
- 2008-09-11 JP JP2010524399A patent/JP5697448B2/ja active Active
- 2008-09-11 EP EP16196638.7A patent/EP3147375A1/en not_active Withdrawn
- 2008-09-11 DK DK08802026.8T patent/DK2198042T3/en active
- 2008-09-11 ES ES08802026.8T patent/ES2605237T3/es active Active
-
2014
- 2014-10-09 JP JP2014208231A patent/JP2015051006A/ja active Pending
-
2016
- 2016-03-24 US US15/079,948 patent/US10113202B2/en active Active
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