JP5670440B2 - １１β−ヒドロキシステロイドデヒドロゲナーゼ１の環状阻害剤 - Google Patents

１１β−ヒドロキシステロイドデヒドロゲナーゼ１の環状阻害剤 Download PDF

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JP5670440B2
JP5670440B2 JP2012513586A JP2012513586A JP5670440B2 JP 5670440 B2 JP5670440 B2 JP 5670440B2 JP 2012513586 A JP2012513586 A JP 2012513586A JP 2012513586 A JP2012513586 A JP 2012513586A JP 5670440 B2 JP5670440 B2 JP 5670440B2
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alkyl
alkoxy
optionally substituted
hydroxy
halo
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JP2012528822A (ja
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ヒンメルスバッハ，フランク
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ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング
ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング
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    • C07D265/04—1,3-Oxazines; Hydrogenated 1,3-oxazines
    • C07D265/06—1,3-Oxazines; Hydrogenated 1,3-oxazines not condensed with other rings
    • C07D265/08—1,3-Oxazines; Hydrogenated 1,3-oxazines not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D265/10—1,3-Oxazines; Hydrogenated 1,3-oxazines not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with oxygen atoms directly attached to ring carbon atoms
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    • C07D413/10—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing aromatic rings

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  • Diabetes (AREA)
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  • Heart & Thoracic Surgery (AREA)
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  • Ophthalmology & Optometry (AREA)
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JP2012513586A 2009-06-02 2010-06-01 １１β−ヒドロキシステロイドデヒドロゲナーゼ１の環状阻害剤 Active JP5670440B2 (ja)

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US21760909P 2009-06-02 2009-06-02
US61/217,609 2009-06-02
PCT/EP2010/057581 WO2010139673A1 (en) 2009-06-02 2010-06-01 Cyclic inhibitors of 11beta-hydroxysteroid dehydrogenase 1

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JP2012528822A JP2012528822A (ja) 2012-11-15
JP2012528822A5 JP2012528822A5 (enExample) 2013-07-18
JP5670440B2 true JP5670440B2 (ja) 2015-02-18

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US (1) US8703765B2 (enExample)
EP (1) EP2438049B1 (enExample)
JP (1) JP5670440B2 (enExample)
WO (1) WO2010139673A1 (enExample)

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US8703765B2 (en) 2014-04-22
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