JP5670183B2 - 原核生物フェニルアラニンアンモニアリアーゼの組成物、及び、その組成物の使用方法 - Google Patents

原核生物フェニルアラニンアンモニアリアーゼの組成物、及び、その組成物の使用方法 Download PDF

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JP5670183B2
JP5670183B2 JP2010509405A JP2010509405A JP5670183B2 JP 5670183 B2 JP5670183 B2 JP 5670183B2 JP 2010509405 A JP2010509405 A JP 2010509405A JP 2010509405 A JP2010509405 A JP 2010509405A JP 5670183 B2 JP5670183 B2 JP 5670183B2
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avpal
pal
protein
peg
pegylated
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JP2010529835A (ja
JP2010529835A5 (enExample
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シー．ベルラルド ミクヘル
シー．ベルラルド ミクヘル
エー．フイトズパトリクク パウル
エー．フイトズパトリクク パウル
ディー．カッキス エミル
ディー．カッキス エミル
ジェイ．ウエンドト ダニエル
ジェイ．ウエンドト ダニエル
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ビオマリン プハルマセウトイカル インコーポレイテッド
ビオマリン プハルマセウトイカル インコーポレイテッド
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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/88—Lyases (4.)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/43—Enzymes; Proenzymes; Derivatives thereof
    • A61K38/51—Lyases (4)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/02—Antineoplastic agents specific for leukemia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Zoology (AREA)
  • Genetics & Genomics (AREA)
  • Wood Science & Technology (AREA)
  • Biomedical Technology (AREA)
  • Hematology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Diabetes (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Immunology (AREA)
  • Epidemiology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Oncology (AREA)
  • Obesity (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Peptides Or Proteins (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
JP2010509405A 2007-05-25 2008-05-23 原核生物フェニルアラニンアンモニアリアーゼの組成物、及び、その組成物の使用方法 Active JP5670183B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US11/807,227 US7534595B2 (en) 2006-06-12 2007-05-25 Compositions of prokaryotic phenylalanine ammonia-lyase and methods of using compositions thereof
US11/807,227 2007-05-25
PCT/US2008/006661 WO2008153776A1 (en) 2007-05-25 2008-05-23 Compositions of prokaryotic phenylalanine ammonia-lyase and methods of using said compositions

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JP2010529835A JP2010529835A (ja) 2010-09-02
JP2010529835A5 JP2010529835A5 (enExample) 2011-07-07
JP5670183B2 true JP5670183B2 (ja) 2015-02-18

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US (1) US7534595B2 (enExample)
EP (2) EP2152868B1 (enExample)
JP (1) JP5670183B2 (enExample)
KR (2) KR101603796B1 (enExample)
CN (1) CN101842482B (enExample)
AR (2) AR066716A1 (enExample)
AU (1) AU2008263190B2 (enExample)
BR (1) BRPI0811267B8 (enExample)
CA (1) CA2687450C (enExample)
CL (1) CL2008001497A1 (enExample)
CY (2) CY1116894T1 (enExample)
DK (1) DK2152868T3 (enExample)
EA (1) EA018443B1 (enExample)
ES (1) ES2551315T3 (enExample)
HR (1) HRP20151268T1 (enExample)
HU (2) HUE025784T2 (enExample)
IL (1) IL202132A (enExample)
LT (1) LTC2152868I2 (enExample)
LU (1) LUC00133I2 (enExample)
MX (1) MX2009012453A (enExample)
MY (1) MY151413A (enExample)
NL (1) NL301011I2 (enExample)
NO (1) NO2019037I1 (enExample)
PE (1) PE20090315A1 (enExample)
PL (1) PL2152868T3 (enExample)
PT (1) PT2152868E (enExample)
SI (1) SI2152868T1 (enExample)
TW (1) TWI418633B (enExample)
WO (1) WO2008153776A1 (enExample)

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TW202144575A (zh) 2020-04-03 2021-12-01 美商拜奧馬林製藥公司 使用ａａｖ及治療調配物之苯酮尿症治療
JP2023539632A (ja) 2020-08-28 2023-09-15 コデクシス， インコーポレイテッド 操作されたプロテアーゼバリアント
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LUC00133I2 (enExample) 2020-07-16
LTPA2019517I1 (lt) 2019-10-25
EP2657335A1 (en) 2013-10-30
SI2152868T1 (sl) 2015-12-31
LTC2152868I2 (lt) 2020-09-25
EP2152868B1 (en) 2015-09-02
MY151413A (en) 2014-05-30
MX2009012453A (es) 2010-01-25
IL202132A0 (en) 2010-06-16
EA018443B1 (ru) 2013-08-30
HRP20151268T1 (hr) 2015-12-18
WO2008153776A8 (en) 2009-07-30
WO2008153776A1 (en) 2008-12-18
TWI418633B (zh) 2013-12-11
AU2008263190B2 (en) 2014-04-17
CY2019039I1 (el) 2020-05-29
HUE025784T2 (en) 2016-05-30
JP2010529835A (ja) 2010-09-02
EA200970980A1 (ru) 2010-04-30
AR110834A2 (es) 2019-05-08
KR20150038753A (ko) 2015-04-08
TW200902052A (en) 2009-01-16
US7534595B2 (en) 2009-05-19
LUC00133I1 (enExample) 2019-10-16
CA2687450A1 (en) 2008-12-18
CY1116894T1 (el) 2017-04-05
BRPI0811267B1 (pt) 2020-11-10
CL2008001497A1 (es) 2009-01-09
ES2551315T3 (es) 2015-11-18
AR066716A1 (es) 2009-09-09
BRPI0811267B8 (pt) 2021-05-25
IL202132A (en) 2017-06-29
PL2152868T3 (pl) 2016-01-29
CN101842482A (zh) 2010-09-22
KR101603796B1 (ko) 2016-03-17
HK1135141A1 (zh) 2010-05-28
NO2019037I1 (no) 2019-10-16
CY2019039I2 (el) 2020-05-29
NL301011I2 (nl) 2020-05-13
BRPI0811267A2 (pt) 2014-10-07
CN101842482B (zh) 2014-10-22
US20080008695A1 (en) 2008-01-10
EP2152868A1 (en) 2010-02-17
KR20100024437A (ko) 2010-03-05
NL301011I1 (nl) 2019-10-16
CA2687450C (en) 2019-03-26
PT2152868E (pt) 2015-11-13
PE20090315A1 (es) 2009-03-19
AU2008263190A1 (en) 2008-12-18
HUS1900049I1 (hu) 2019-11-28
DK2152868T3 (en) 2015-11-16

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