JP5606734B2 - 医薬化合物 - Google Patents

医薬化合物 Download PDF

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Publication number
JP5606734B2
JP5606734B2 JP2009507156A JP2009507156A JP5606734B2 JP 5606734 B2 JP5606734 B2 JP 5606734B2 JP 2009507156 A JP2009507156 A JP 2009507156A JP 2009507156 A JP2009507156 A JP 2009507156A JP 5606734 B2 JP5606734 B2 JP 5606734B2
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JP
Japan
Prior art keywords
group
groups
formula
acid
compound
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Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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JP2009507156A
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English (en)
Japanese (ja)
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JP2009534455A5 (enExample
JP2009534455A (ja
Inventor
トーマス、グランモア、デービス
ミシェル、ドーン、ガレット
ロバート、ジョージ、ボイル
イアン、コリンズ
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Cancer Research Technology Ltd
Astex Therapeutics Ltd
Original Assignee
Cancer Research Technology Ltd
Astex Therapeutics Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB0608179A external-priority patent/GB0608179D0/en
Priority claimed from GB0608176A external-priority patent/GB0608176D0/en
Application filed by Cancer Research Technology Ltd, Astex Therapeutics Ltd filed Critical Cancer Research Technology Ltd
Publication of JP2009534455A publication Critical patent/JP2009534455A/ja
Publication of JP2009534455A5 publication Critical patent/JP2009534455A5/ja
Application granted granted Critical
Publication of JP5606734B2 publication Critical patent/JP5606734B2/ja
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D473/00—Heterocyclic compounds containing purine ring systems
    • C07D473/26—Heterocyclic compounds containing purine ring systems with an oxygen, sulphur, or nitrogen atom directly attached in position 2 or 6, but not in both
    • C07D473/32—Nitrogen atom
    • C07D473/34—Nitrogen atom attached in position 6, e.g. adenine
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
JP2009507156A 2006-04-25 2007-04-25 医薬化合物 Active JP5606734B2 (ja)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
GB0608176.4 2006-04-25
GB0608179.8 2006-04-25
GB0608179A GB0608179D0 (en) 2006-04-25 2006-04-25 Pharmaceutical compounds
GB0608176A GB0608176D0 (en) 2006-04-25 2006-04-25 Pharmaceutical Compounds
PCT/GB2007/001518 WO2007125321A2 (en) 2006-04-25 2007-04-25 Purine and deazapurine derivatives as pharmaceutical compounds

Publications (3)

Publication Number Publication Date
JP2009534455A JP2009534455A (ja) 2009-09-24
JP2009534455A5 JP2009534455A5 (enExample) 2010-06-17
JP5606734B2 true JP5606734B2 (ja) 2014-10-15

Family

ID=38255445

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2009507156A Active JP5606734B2 (ja) 2006-04-25 2007-04-25 医薬化合物

Country Status (7)

Country Link
US (1) US8796293B2 (enExample)
EP (3) EP3719018B1 (enExample)
JP (1) JP5606734B2 (enExample)
DK (2) DK3719018T3 (enExample)
ES (2) ES2878130T3 (enExample)
FI (1) FI3719018T3 (enExample)
WO (1) WO2007125321A2 (enExample)

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Also Published As

Publication number Publication date
EP3719018B1 (en) 2025-08-27
US20100022564A1 (en) 2010-01-28
EP3719018A1 (en) 2020-10-07
EP3421471A1 (en) 2019-01-02
DK3421471T3 (da) 2021-06-14
WO2007125321A2 (en) 2007-11-08
DK3719018T3 (da) 2025-09-29
WO2007125321A3 (en) 2007-12-27
EP2043655A2 (en) 2009-04-08
HK1257844A1 (en) 2019-11-01
ES3043833T3 (en) 2025-11-25
FI3719018T3 (fi) 2025-10-07
US8796293B2 (en) 2014-08-05
JP2009534455A (ja) 2009-09-24
EP3421471B1 (en) 2021-05-26
ES2878130T3 (es) 2021-11-18

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