ES2878130T3 - Derivados de purina y deazapurina como compuestos farmacéuticos - Google Patents

Derivados de purina y deazapurina como compuestos farmacéuticos Download PDF

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Publication number
ES2878130T3
ES2878130T3 ES18182786T ES18182786T ES2878130T3 ES 2878130 T3 ES2878130 T3 ES 2878130T3 ES 18182786 T ES18182786 T ES 18182786T ES 18182786 T ES18182786 T ES 18182786T ES 2878130 T3 ES2878130 T3 ES 2878130T3
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ES
Spain
Prior art keywords
group
groups
compound
carbocyclic
mmol
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
ES18182786T
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English (en)
Spanish (es)
Inventor
Thomas Davies
Robert Boyle
Ian Collins
Michelle Garrett
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Institute of Cancer Research Royal Cancer Hospital
Cancer Research Technology Ltd
Astex Therapeutics Ltd
Original Assignee
Institute of Cancer Research Royal Cancer Hospital
Cancer Research Technology Ltd
Astex Therapeutics Ltd
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Filing date
Publication date
Priority claimed from GB0608176A external-priority patent/GB0608176D0/en
Priority claimed from GB0608179A external-priority patent/GB0608179D0/en
Application filed by Institute of Cancer Research Royal Cancer Hospital, Cancer Research Technology Ltd, Astex Therapeutics Ltd filed Critical Institute of Cancer Research Royal Cancer Hospital
Application granted granted Critical
Publication of ES2878130T3 publication Critical patent/ES2878130T3/es
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D473/00—Heterocyclic compounds containing purine ring systems
    • C07D473/26—Heterocyclic compounds containing purine ring systems with an oxygen, sulphur, or nitrogen atom directly attached in position 2 or 6, but not in both
    • C07D473/32—Nitrogen atom
    • C07D473/34—Nitrogen atom attached in position 6, e.g. adenine
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
ES18182786T 2006-04-25 2007-04-25 Derivados de purina y deazapurina como compuestos farmacéuticos Active ES2878130T3 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB0608176A GB0608176D0 (en) 2006-04-25 2006-04-25 Pharmaceutical Compounds
GB0608179A GB0608179D0 (en) 2006-04-25 2006-04-25 Pharmaceutical compounds

Publications (1)

Publication Number Publication Date
ES2878130T3 true ES2878130T3 (es) 2021-11-18

Family

ID=38255445

Family Applications (2)

Application Number Title Priority Date Filing Date
ES18182786T Active ES2878130T3 (es) 2006-04-25 2007-04-25 Derivados de purina y deazapurina como compuestos farmacéuticos
ES19216213T Active ES3043833T3 (en) 2006-04-25 2007-04-25 Purine and deazapurine derivatives as pharmaceutical compounds

Family Applications After (1)

Application Number Title Priority Date Filing Date
ES19216213T Active ES3043833T3 (en) 2006-04-25 2007-04-25 Purine and deazapurine derivatives as pharmaceutical compounds

Country Status (7)

Country Link
US (1) US8796293B2 (enExample)
EP (3) EP3719018B1 (enExample)
JP (1) JP5606734B2 (enExample)
DK (2) DK3421471T3 (enExample)
ES (2) ES2878130T3 (enExample)
FI (1) FI3719018T3 (enExample)
WO (1) WO2007125321A2 (enExample)

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Also Published As

Publication number Publication date
EP3421471B1 (en) 2021-05-26
DK3421471T3 (da) 2021-06-14
EP2043655A2 (en) 2009-04-08
JP2009534455A (ja) 2009-09-24
JP5606734B2 (ja) 2014-10-15
HK1257844A1 (en) 2019-11-01
FI3719018T3 (fi) 2025-10-07
ES3043833T3 (en) 2025-11-25
WO2007125321A2 (en) 2007-11-08
US20100022564A1 (en) 2010-01-28
WO2007125321A3 (en) 2007-12-27
US8796293B2 (en) 2014-08-05
EP3421471A1 (en) 2019-01-02
EP3719018B1 (en) 2025-08-27
EP3719018A1 (en) 2020-10-07
DK3719018T3 (da) 2025-09-29

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