JP5579443B2 - マイクロ流体デバイス - Google Patents
マイクロ流体デバイス Download PDFInfo
- Publication number
- JP5579443B2 JP5579443B2 JP2009545993A JP2009545993A JP5579443B2 JP 5579443 B2 JP5579443 B2 JP 5579443B2 JP 2009545993 A JP2009545993 A JP 2009545993A JP 2009545993 A JP2009545993 A JP 2009545993A JP 5579443 B2 JP5579443 B2 JP 5579443B2
- Authority
- JP
- Japan
- Prior art keywords
- film
- microfluidic device
- layer
- membrane
- melting temperature
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Active
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Classifications
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
- B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
- B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
- B01L3/5027—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
- B01L3/502707—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip characterised by the manufacture of the container or its components
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J19/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
- B01J19/0093—Microreactors, e.g. miniaturised or microfabricated reactors
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B32—LAYERED PRODUCTS
- B32B—LAYERED PRODUCTS, i.e. PRODUCTS BUILT-UP OF STRATA OF FLAT OR NON-FLAT, e.g. CELLULAR OR HONEYCOMB, FORM
- B32B27/00—Layered products comprising a layer of synthetic resin
- B32B27/06—Layered products comprising a layer of synthetic resin as the main or only constituent of a layer, which is next to another layer of the same or of a different material
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
- B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
- B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
- B01L3/5027—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
- B01L3/502738—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip characterised by integrated valves
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B32—LAYERED PRODUCTS
- B32B—LAYERED PRODUCTS, i.e. PRODUCTS BUILT-UP OF STRATA OF FLAT OR NON-FLAT, e.g. CELLULAR OR HONEYCOMB, FORM
- B32B27/00—Layered products comprising a layer of synthetic resin
- B32B27/32—Layered products comprising a layer of synthetic resin comprising polyolefins
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2200/00—Solutions for specific problems relating to chemical or physical laboratory apparatus
- B01L2200/12—Specific details about manufacturing devices
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2300/00—Additional constructional details
- B01L2300/06—Auxiliary integrated devices, integrated components
- B01L2300/0627—Sensor or part of a sensor is integrated
- B01L2300/0645—Electrodes
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2300/00—Additional constructional details
- B01L2300/08—Geometry, shape and general structure
- B01L2300/0887—Laminated structure
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2300/00—Additional constructional details
- B01L2300/12—Specific details about materials
- B01L2300/123—Flexible; Elastomeric
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2400/00—Moving or stopping fluids
- B01L2400/06—Valves, specific forms thereof
- B01L2400/0633—Valves, specific forms thereof with moving parts
- B01L2400/0638—Valves, specific forms thereof with moving parts membrane valves, flap valves
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B32—LAYERED PRODUCTS
- B32B—LAYERED PRODUCTS, i.e. PRODUCTS BUILT-UP OF STRATA OF FLAT OR NON-FLAT, e.g. CELLULAR OR HONEYCOMB, FORM
- B32B2307/00—Properties of the layers or laminate
- B32B2307/70—Other properties
- B32B2307/726—Permeability to liquids, absorption
- B32B2307/7265—Non-permeable
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B32—LAYERED PRODUCTS
- B32B—LAYERED PRODUCTS, i.e. PRODUCTS BUILT-UP OF STRATA OF FLAT OR NON-FLAT, e.g. CELLULAR OR HONEYCOMB, FORM
- B32B2323/00—Polyalkenes
- B32B2323/04—Polyethylene
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B32—LAYERED PRODUCTS
- B32B—LAYERED PRODUCTS, i.e. PRODUCTS BUILT-UP OF STRATA OF FLAT OR NON-FLAT, e.g. CELLULAR OR HONEYCOMB, FORM
- B32B2323/00—Polyalkenes
- B32B2323/10—Polypropylene
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Clinical Laboratory Science (AREA)
- General Health & Medical Sciences (AREA)
- Hematology (AREA)
- Analytical Chemistry (AREA)
- Dispersion Chemistry (AREA)
- Organic Chemistry (AREA)
- Physical Or Chemical Processes And Apparatus (AREA)
- Micromachines (AREA)
- Automatic Analysis And Handling Materials Therefor (AREA)
- Apparatus Associated With Microorganisms And Enzymes (AREA)
- Laminated Bodies (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB0700822.0 | 2007-01-16 | ||
| GB0700822A GB2445738A (en) | 2007-01-16 | 2007-01-16 | Microfluidic device |
| PCT/GB2008/000143 WO2008087405A1 (en) | 2007-01-16 | 2008-01-16 | Microfluidic device |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2010515924A JP2010515924A (ja) | 2010-05-13 |
| JP2010515924A5 JP2010515924A5 (enExample) | 2010-12-09 |
| JP5579443B2 true JP5579443B2 (ja) | 2014-08-27 |
Family
ID=37810038
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2009545993A Active JP5579443B2 (ja) | 2007-01-16 | 2008-01-16 | マイクロ流体デバイス |
Country Status (6)
| Country | Link |
|---|---|
| US (1) | US20100175999A1 (enExample) |
| EP (1) | EP2114570B1 (enExample) |
| JP (1) | JP5579443B2 (enExample) |
| CN (1) | CN101674888B (enExample) |
| GB (1) | GB2445738A (enExample) |
| WO (1) | WO2008087405A1 (enExample) |
Families Citing this family (36)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP4685329B2 (ja) * | 2000-10-24 | 2011-05-18 | ハンス イエンセン ルブリカトーズ アクティーゼルスカブ | 分配装置 |
| ES2548567T3 (es) | 2004-04-07 | 2015-10-19 | Levine, Robert Aaron | Cámara desechable para analizar fluidos biológicos |
| US8715446B2 (en) * | 2004-10-13 | 2014-05-06 | Rheonix, Inc. | Latent solvent-based microfluidic apparatus, methods, and applications |
| US7731901B2 (en) | 2005-10-19 | 2010-06-08 | Abbott Laboratories | Apparatus and method for performing counts within a biologic fluid sample |
| GB2445739A (en) | 2007-01-16 | 2008-07-23 | Lab901 Ltd | Polymeric laminates containing heat seals |
| ES2352581T3 (es) * | 2008-06-02 | 2011-02-21 | Boehringer Ingelheim Microparts Gmbh | Estructura de lámina microfluídica para dosificar líquidos. |
| JP2011030522A (ja) * | 2009-08-04 | 2011-02-17 | Aida Engineering Ltd | マイクロ流体デバイス |
| EP2512647A2 (en) * | 2009-12-18 | 2012-10-24 | Abbott Point Of Care, Inc. | Biologic fluid analysis cartridge |
| US8720036B2 (en) | 2010-03-09 | 2014-05-13 | Netbio, Inc. | Unitary biochip providing sample-in to results-out processing and methods of manufacture |
| KR101796110B1 (ko) | 2010-03-09 | 2017-11-10 | 네트바이오, 인코포레이티드 | 샘플 투입 및 결과 발생 처리를 제공하기 위한 단일한 바이오칩 및 이의 제조 방법 |
| CN101823686B (zh) * | 2010-04-21 | 2012-07-04 | 大连理工大学 | 一种热塑性聚合物多层微流控芯片封合方法 |
| JP5582049B2 (ja) * | 2010-05-31 | 2014-09-03 | 横河電機株式会社 | 化学処理用カートリッジシステム |
| WO2012028595A1 (de) * | 2010-09-01 | 2012-03-08 | Boehringer Ingelheim Microparts Gmbh | Verfahren zum herstellen einer mikrofluidischen vorrichtung sowie diesbezügliche laminiereinrichtungen |
| ES2533839T3 (es) | 2010-12-30 | 2015-04-15 | Abbott Point Of Care, Inc. | Cartucho de análisis de fluido biológico con porción de manipulación de muestra y porción de cámara de análisis |
| US20130137144A1 (en) * | 2011-06-08 | 2013-05-30 | Bio-Rad Laboratories, Inc. LSG - GXD Division | Thermal block with built-in thermoelectric elements |
| CN103890590B (zh) | 2011-08-24 | 2016-03-09 | 艾博特健康公司 | 生物流体样品分析盒 |
| WO2013102071A1 (en) * | 2011-12-30 | 2013-07-04 | Abbott Molecular, Inc. | Chemical reaction vessels |
| EP2869922B1 (en) * | 2013-01-09 | 2019-11-20 | Tecan Trading AG | Disposable cartridge for microfluidics systems |
| WO2014116979A1 (en) | 2013-01-24 | 2014-07-31 | Sabic Innovative Plastics Ip B.V. | Microwell plate made from a polyester-polycarbonate |
| EP2948251A1 (en) | 2013-01-24 | 2015-12-02 | SABIC Global Technologies B.V. | Microwell plate made from a polyester-polycarbonate |
| WO2014116951A2 (en) | 2013-01-24 | 2014-07-31 | Sabic Innovative Plastics Ip B.V. | Polycarbonate microfluidic articles |
| JP6012518B2 (ja) * | 2013-03-21 | 2016-10-25 | 株式会社日立ハイテクノロジーズ | 生化学カートリッジ用温調機構、温調ブロック及び生化学処理装置 |
| EP3129652A4 (en) | 2014-04-11 | 2018-01-10 | President and Fellows of Harvard College | High throughput fabrication of soft machines |
| CN104607256A (zh) * | 2014-12-31 | 2015-05-13 | 北京同方生物芯片技术有限公司 | 等离子体辅助热压键合微流控芯片及其制备方法 |
| US9845499B2 (en) * | 2016-04-04 | 2017-12-19 | Combinati Incorporated | Microfluidic siphoning array for nucleic acid quantification |
| US11285478B2 (en) | 2016-04-04 | 2022-03-29 | Combinati Incorporated | Microfluidic siphoning array for nucleic acid quantification |
| AU2017363076B2 (en) | 2016-11-17 | 2021-04-29 | Combinati Incorporated | Methods and systems for nucleic acid analysis and quantification |
| EP3384987A3 (en) * | 2017-04-03 | 2018-10-24 | CSEM Centre Suisse d'Electronique et de Microtechnique SA - Recherche et Développement | Vessel for performing electrochemical measurements and method for manufacturing such vessel |
| WO2019035079A1 (en) | 2017-08-17 | 2019-02-21 | Abbott Point Of Care Inc. | DEVICES, SYSTEMS AND METHODS FOR PERFORMING OPTICAL AND ELECTROCHEMICAL ASSAYS |
| CN110869745B (zh) | 2017-08-17 | 2023-08-11 | 雅培医护站股份有限公司 | 用于执行光学测定的设备、系统和方法 |
| CN107739706B (zh) * | 2017-09-26 | 2020-04-14 | 南京岚煜生物科技有限公司 | 主动控制流路的多通量微流控核酸检测芯片及其使用方法 |
| DE102018217907B3 (de) * | 2018-10-19 | 2019-12-19 | SpinDiag GmbH | Probenbehälter |
| CA3122712A1 (en) | 2018-12-10 | 2020-06-18 | Combinati Incorporated | Microfluidic array for sample digitization |
| CN112569881B (zh) * | 2020-07-24 | 2021-07-20 | 苏州恒瑞宏远医疗科技有限公司 | 一种反应装置及其加工方法 |
| DE102020202767B3 (de) * | 2020-03-04 | 2021-05-27 | Hahn-Schickard-Gesellschaft für angewandte Forschung e.V. | Herstellung eines Verbunds aus Polymersubstraten und gesiegelte mikrofluidische Kartusche |
| CA3195362A1 (en) | 2020-09-28 | 2022-03-31 | Combinati Incorporated | Devices and methods for sample processing |
Family Cites Families (26)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4333968A (en) * | 1980-01-25 | 1982-06-08 | Mobil Oil Corporation | Thermoplastic packaging films with improved heat-seal characteristics |
| WO1994026414A1 (en) * | 1993-05-17 | 1994-11-24 | Syntex (U.S.A.) Inc. | Reaction container for specific binding assays and method for its use |
| US5500071A (en) * | 1994-10-19 | 1996-03-19 | Hewlett-Packard Company | Miniaturized planar columns in novel support media for liquid phase analysis |
| US5658413A (en) * | 1994-10-19 | 1997-08-19 | Hewlett-Packard Company | Miniaturized planar columns in novel support media for liquid phase analysis |
| US5525405A (en) * | 1994-12-14 | 1996-06-11 | E. I. Du Pont De Nemours And Company | Adhesiveless aromatic polyimide laminate |
| JP3839524B2 (ja) * | 1995-06-07 | 2006-11-01 | アジレント・テクノロジーズ・インク | 小型化全分析システム |
| US5932799A (en) * | 1997-07-21 | 1999-08-03 | Ysi Incorporated | Microfluidic analyzer module |
| US6375871B1 (en) * | 1998-06-18 | 2002-04-23 | 3M Innovative Properties Company | Methods of manufacturing microfluidic articles |
| US6627159B1 (en) * | 2000-06-28 | 2003-09-30 | 3M Innovative Properties Company | Centrifugal filling of sample processing devices |
| US20020150502A1 (en) * | 2001-04-03 | 2002-10-17 | Weigl Bernhard H. | Surface tension reduction channel |
| WO2002086333A1 (en) * | 2001-04-25 | 2002-10-31 | President And Fellows Of Harvard College | Fluidic switches and method for controlling flow in fluidic systems |
| US20030118804A1 (en) * | 2001-05-02 | 2003-06-26 | 3M Innovative Properties Company | Sample processing device with resealable process chamber |
| JP2003028877A (ja) * | 2001-07-17 | 2003-01-29 | Sekisui Chem Co Ltd | 反応チップ用担体及び反応チップ |
| GB0128350D0 (en) * | 2001-11-27 | 2002-01-16 | Lab901 Ltd | Non-rigid apparatus for microfluidic applications |
| JP2003220330A (ja) * | 2002-01-31 | 2003-08-05 | Asahi Kasei Corp | 透明ポリマーチップ |
| TWI227196B (en) * | 2002-02-22 | 2005-02-01 | Clopay Plastic Prod Co | Film, laminated sheet and methods of making same |
| US20040101657A1 (en) * | 2002-08-19 | 2004-05-27 | Moles Donald R. | Method of microfluidic construction using composite polymer films |
| US7431888B2 (en) * | 2002-09-20 | 2008-10-07 | The Regents Of The University Of California | Photoinitiated grafting of porous polymer monoliths and thermoplastic polymers for microfluidic devices |
| CA2772050C (en) * | 2002-12-26 | 2016-09-06 | Meso Scale Technologies, Llc. | Assay cartridges and methods of using the same |
| EP2574400B1 (en) * | 2003-02-05 | 2016-09-28 | Iquum, Inc. | Sample processing |
| AU2004228678A1 (en) * | 2003-04-03 | 2004-10-21 | Fluidigm Corp. | Microfluidic devices and methods of using same |
| JP2006076246A (ja) * | 2004-09-13 | 2006-03-23 | Rohm Co Ltd | 基板の貼り合わせ方法、その貼り合わせ方法を用いたチップ形成方法及びチップ |
| JP4547216B2 (ja) * | 2004-09-17 | 2010-09-22 | 東洋製罐株式会社 | ガスバリアー性及び層間接着性に優れた多層容器 |
| CA2594483C (en) * | 2005-01-28 | 2014-08-26 | Duke University | Apparatuses and methods for manipulating droplets on a printed circuit board |
| US20060272716A1 (en) * | 2005-05-12 | 2006-12-07 | University Of Washington | Method of adhesiveless lamination of polymer films into microfluidic networks with high dimensional fidelity |
| US20100291588A1 (en) * | 2005-06-24 | 2010-11-18 | The Board Of Regents Of The University Of Texas System | Systems and methods including self-contained cartridges with detection systems and fluid delivery systems |
-
2007
- 2007-01-16 GB GB0700822A patent/GB2445738A/en not_active Withdrawn
-
2008
- 2008-01-16 WO PCT/GB2008/000143 patent/WO2008087405A1/en not_active Ceased
- 2008-01-16 EP EP08701821.4A patent/EP2114570B1/en active Active
- 2008-01-16 JP JP2009545993A patent/JP5579443B2/ja active Active
- 2008-01-16 CN CN2008800065615A patent/CN101674888B/zh active Active
- 2008-01-16 US US12/523,500 patent/US20100175999A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| CN101674888A (zh) | 2010-03-17 |
| US20100175999A1 (en) | 2010-07-15 |
| WO2008087405A1 (en) | 2008-07-24 |
| EP2114570B1 (en) | 2013-06-05 |
| EP2114570A1 (en) | 2009-11-11 |
| JP2010515924A (ja) | 2010-05-13 |
| GB2445738A (en) | 2008-07-23 |
| CN101674888B (zh) | 2012-06-13 |
| GB0700822D0 (en) | 2007-02-21 |
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