GB2445738A - Microfluidic device - Google Patents
Microfluidic device Download PDFInfo
- Publication number
- GB2445738A GB2445738A GB0700822A GB0700822A GB2445738A GB 2445738 A GB2445738 A GB 2445738A GB 0700822 A GB0700822 A GB 0700822A GB 0700822 A GB0700822 A GB 0700822A GB 2445738 A GB2445738 A GB 2445738A
- Authority
- GB
- United Kingdom
- Prior art keywords
- film
- films
- layer
- relatively
- melting point
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Withdrawn
Links
- 239000000463 material Substances 0.000 claims abstract description 58
- -1 polyethylene Polymers 0.000 claims abstract description 26
- 239000012530 fluid Substances 0.000 claims abstract description 23
- 238000002844 melting Methods 0.000 claims abstract description 21
- 230000008018 melting Effects 0.000 claims abstract description 21
- 239000004698 Polyethylene Substances 0.000 claims abstract description 20
- 229920000573 polyethylene Polymers 0.000 claims abstract description 20
- 229920001169 thermoplastic Polymers 0.000 claims abstract description 19
- 239000004416 thermosoftening plastic Substances 0.000 claims abstract description 19
- 229920000089 Cyclic olefin copolymer Polymers 0.000 claims abstract description 15
- 239000004713 Cyclic olefin copolymer Substances 0.000 claims abstract description 15
- 239000000203 mixture Substances 0.000 claims abstract description 8
- 239000004952 Polyamide Substances 0.000 claims abstract description 7
- 229920002647 polyamide Polymers 0.000 claims abstract description 7
- 238000001962 electrophoresis Methods 0.000 claims abstract description 5
- 229920003229 poly(methyl methacrylate) Polymers 0.000 claims abstract description 5
- 239000004926 polymethyl methacrylate Substances 0.000 claims abstract description 5
- 229920001577 copolymer Polymers 0.000 claims abstract description 4
- 239000004417 polycarbonate Substances 0.000 claims abstract description 3
- 229920000515 polycarbonate Polymers 0.000 claims abstract description 3
- 229920000728 polyester Polymers 0.000 claims abstract description 3
- 238000006243 chemical reaction Methods 0.000 claims description 30
- 238000000034 method Methods 0.000 claims description 18
- 238000004519 manufacturing process Methods 0.000 claims description 8
- 238000003856 thermoforming Methods 0.000 claims description 8
- 239000000155 melt Substances 0.000 claims description 5
- 230000015572 biosynthetic process Effects 0.000 claims description 3
- 239000011541 reaction mixture Substances 0.000 claims description 2
- 230000004888 barrier function Effects 0.000 abstract description 8
- 239000007788 liquid Substances 0.000 abstract description 4
- 239000004715 ethylene vinyl alcohol Substances 0.000 abstract description 3
- 229920000219 Ethylene vinyl alcohol Polymers 0.000 abstract description 2
- UFRKOOWSQGXVKV-UHFFFAOYSA-N ethene;ethenol Chemical compound C=C.OC=C UFRKOOWSQGXVKV-UHFFFAOYSA-N 0.000 abstract 1
- 239000010408 film Substances 0.000 description 69
- 229920001971 elastomer Polymers 0.000 description 13
- 239000000806 elastomer Substances 0.000 description 13
- 238000003752 polymerase chain reaction Methods 0.000 description 8
- 239000004743 Polypropylene Substances 0.000 description 6
- 238000004458 analytical method Methods 0.000 description 6
- 229920001155 polypropylene Polymers 0.000 description 6
- 239000011800 void material Substances 0.000 description 6
- 238000013461 design Methods 0.000 description 5
- 238000011161 development Methods 0.000 description 5
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- 239000007789 gas Substances 0.000 description 5
- 238000003475 lamination Methods 0.000 description 5
- 239000003153 chemical reaction reagent Substances 0.000 description 4
- 238000001125 extrusion Methods 0.000 description 4
- 230000003287 optical effect Effects 0.000 description 4
- 229920000642 polymer Polymers 0.000 description 4
- WKBPZYKAUNRMKP-UHFFFAOYSA-N 1-[2-(2,4-dichlorophenyl)pentyl]1,2,4-triazole Chemical compound C=1C=C(Cl)C=C(Cl)C=1C(CCC)CN1C=NC=N1 WKBPZYKAUNRMKP-UHFFFAOYSA-N 0.000 description 3
- 238000010438 heat treatment Methods 0.000 description 3
- 238000009396 hybridization Methods 0.000 description 3
- 108020004707 nucleic acids Proteins 0.000 description 3
- 102000039446 nucleic acids Human genes 0.000 description 3
- 150000007523 nucleic acids Chemical class 0.000 description 3
- BASFCYQUMIYNBI-UHFFFAOYSA-N platinum Chemical compound [Pt] BASFCYQUMIYNBI-UHFFFAOYSA-N 0.000 description 3
- 229920001721 polyimide Polymers 0.000 description 3
- 238000012545 processing Methods 0.000 description 3
- 239000000758 substrate Substances 0.000 description 3
- 239000011031 topaz Substances 0.000 description 3
- 229910052853 topaz Inorganic materials 0.000 description 3
- 238000012546 transfer Methods 0.000 description 3
- OKTJSMMVPCPJKN-UHFFFAOYSA-N Carbon Chemical compound [C] OKTJSMMVPCPJKN-UHFFFAOYSA-N 0.000 description 2
- 108020004414 DNA Proteins 0.000 description 2
- 239000012807 PCR reagent Substances 0.000 description 2
- 239000004642 Polyimide Substances 0.000 description 2
- 238000001514 detection method Methods 0.000 description 2
- 238000005516 engineering process Methods 0.000 description 2
- 230000002708 enhancing effect Effects 0.000 description 2
- 239000011521 glass Substances 0.000 description 2
- VNWKTOKETHGBQD-UHFFFAOYSA-N methane Chemical compound C VNWKTOKETHGBQD-UHFFFAOYSA-N 0.000 description 2
- 230000035699 permeability Effects 0.000 description 2
- 229920003023 plastic Polymers 0.000 description 2
- 239000004033 plastic Substances 0.000 description 2
- 238000002360 preparation method Methods 0.000 description 2
- 230000008569 process Effects 0.000 description 2
- 229910052710 silicon Inorganic materials 0.000 description 2
- 239000010703 silicon Substances 0.000 description 2
- 238000001179 sorption measurement Methods 0.000 description 2
- 239000000126 substance Substances 0.000 description 2
- 239000010409 thin film Substances 0.000 description 2
- 108091093088 Amplicon Proteins 0.000 description 1
- 229920003313 Bynel® Polymers 0.000 description 1
- 229920000034 Plastomer Polymers 0.000 description 1
- BQCADISMDOOEFD-UHFFFAOYSA-N Silver Chemical compound [Ag] BQCADISMDOOEFD-UHFFFAOYSA-N 0.000 description 1
- 230000003321 amplification Effects 0.000 description 1
- 230000009830 antibody antigen interaction Effects 0.000 description 1
- 125000003118 aryl group Chemical group 0.000 description 1
- 239000000560 biocompatible material Substances 0.000 description 1
- 230000005540 biological transmission Effects 0.000 description 1
- 108010027090 biotin-streptavidin complex Proteins 0.000 description 1
- 229910052799 carbon Inorganic materials 0.000 description 1
- 230000009918 complex formation Effects 0.000 description 1
- 239000012141 concentrate Substances 0.000 description 1
- 239000004020 conductor Substances 0.000 description 1
- 239000013536 elastomeric material Substances 0.000 description 1
- 238000004049 embossing Methods 0.000 description 1
- 239000003623 enhancer Substances 0.000 description 1
- 229920005570 flexible polymer Polymers 0.000 description 1
- 229910002804 graphite Inorganic materials 0.000 description 1
- 239000010439 graphite Substances 0.000 description 1
- RZXDTJIXPSCHCI-UHFFFAOYSA-N hexa-1,5-diene-2,5-diol Chemical compound OC(=C)CCC(O)=C RZXDTJIXPSCHCI-UHFFFAOYSA-N 0.000 description 1
- 238000001746 injection moulding Methods 0.000 description 1
- 239000000976 ink Substances 0.000 description 1
- 238000011835 investigation Methods 0.000 description 1
- 238000002386 leaching Methods 0.000 description 1
- 229920001912 maleic anhydride grafted polyethylene Polymers 0.000 description 1
- 229920001911 maleic anhydride grafted polypropylene Polymers 0.000 description 1
- 238000007567 mass-production technique Methods 0.000 description 1
- 238000005459 micromachining Methods 0.000 description 1
- 238000000386 microscopy Methods 0.000 description 1
- 238000003199 nucleic acid amplification method Methods 0.000 description 1
- 229910052697 platinum Inorganic materials 0.000 description 1
- 229920000307 polymer substrate Polymers 0.000 description 1
- 238000003825 pressing Methods 0.000 description 1
- 238000007639 printing Methods 0.000 description 1
- 108090000623 proteins and genes Proteins 0.000 description 1
- 102000004169 proteins and genes Human genes 0.000 description 1
- 238000011002 quantification Methods 0.000 description 1
- 238000003753 real-time PCR Methods 0.000 description 1
- 238000011160 research Methods 0.000 description 1
- 239000011347 resin Substances 0.000 description 1
- 229920005989 resin Polymers 0.000 description 1
- 239000004065 semiconductor Substances 0.000 description 1
- 239000004332 silver Substances 0.000 description 1
- 229910052709 silver Inorganic materials 0.000 description 1
- 239000000243 solution Substances 0.000 description 1
- 238000012360 testing method Methods 0.000 description 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 1
Classifications
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B32—LAYERED PRODUCTS
- B32B—LAYERED PRODUCTS, i.e. PRODUCTS BUILT-UP OF STRATA OF FLAT OR NON-FLAT, e.g. CELLULAR OR HONEYCOMB, FORM
- B32B27/00—Layered products comprising a layer of synthetic resin
- B32B27/06—Layered products comprising a layer of synthetic resin as the main or only constituent of a layer, which is next to another layer of the same or of a different material
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
- B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
- B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
- B01L3/5027—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
- B01L3/502707—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip characterised by the manufacture of the container or its components
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J19/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
- B01J19/0093—Microreactors, e.g. miniaturised or microfabricated reactors
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
- B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
- B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
- B01L3/5027—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
- B01L3/502738—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip characterised by integrated valves
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B32—LAYERED PRODUCTS
- B32B—LAYERED PRODUCTS, i.e. PRODUCTS BUILT-UP OF STRATA OF FLAT OR NON-FLAT, e.g. CELLULAR OR HONEYCOMB, FORM
- B32B27/00—Layered products comprising a layer of synthetic resin
- B32B27/32—Layered products comprising a layer of synthetic resin comprising polyolefins
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2200/00—Solutions for specific problems relating to chemical or physical laboratory apparatus
- B01L2200/12—Specific details about manufacturing devices
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2300/00—Additional constructional details
- B01L2300/06—Auxiliary integrated devices, integrated components
- B01L2300/0627—Sensor or part of a sensor is integrated
- B01L2300/0645—Electrodes
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2300/00—Additional constructional details
- B01L2300/08—Geometry, shape and general structure
- B01L2300/0887—Laminated structure
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2300/00—Additional constructional details
- B01L2300/12—Specific details about materials
- B01L2300/123—Flexible; Elastomeric
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2400/00—Moving or stopping fluids
- B01L2400/06—Valves, specific forms thereof
- B01L2400/0633—Valves, specific forms thereof with moving parts
- B01L2400/0638—Valves, specific forms thereof with moving parts membrane valves, flap valves
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B32—LAYERED PRODUCTS
- B32B—LAYERED PRODUCTS, i.e. PRODUCTS BUILT-UP OF STRATA OF FLAT OR NON-FLAT, e.g. CELLULAR OR HONEYCOMB, FORM
- B32B2307/00—Properties of the layers or laminate
- B32B2307/70—Other properties
- B32B2307/726—Permeability to liquids, absorption
- B32B2307/7265—Non-permeable
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B32—LAYERED PRODUCTS
- B32B—LAYERED PRODUCTS, i.e. PRODUCTS BUILT-UP OF STRATA OF FLAT OR NON-FLAT, e.g. CELLULAR OR HONEYCOMB, FORM
- B32B2323/00—Polyalkenes
- B32B2323/04—Polyethylene
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B32—LAYERED PRODUCTS
- B32B—LAYERED PRODUCTS, i.e. PRODUCTS BUILT-UP OF STRATA OF FLAT OR NON-FLAT, e.g. CELLULAR OR HONEYCOMB, FORM
- B32B2323/00—Polyalkenes
- B32B2323/10—Polypropylene
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Clinical Laboratory Science (AREA)
- General Health & Medical Sciences (AREA)
- Hematology (AREA)
- Analytical Chemistry (AREA)
- Dispersion Chemistry (AREA)
- Organic Chemistry (AREA)
- Physical Or Chemical Processes And Apparatus (AREA)
- Micromachines (AREA)
- Laminated Bodies (AREA)
- Automatic Analysis And Handling Materials Therefor (AREA)
- Apparatus Associated With Microorganisms And Enzymes (AREA)
Priority Applications (6)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB0700822A GB2445738A (en) | 2007-01-16 | 2007-01-16 | Microfluidic device |
| EP08701821.4A EP2114570B1 (en) | 2007-01-16 | 2008-01-16 | Microfluidic device |
| PCT/GB2008/000143 WO2008087405A1 (en) | 2007-01-16 | 2008-01-16 | Microfluidic device |
| JP2009545993A JP5579443B2 (ja) | 2007-01-16 | 2008-01-16 | マイクロ流体デバイス |
| CN2008800065615A CN101674888B (zh) | 2007-01-16 | 2008-01-16 | 微流体器件 |
| US12/523,500 US20100175999A1 (en) | 2007-01-16 | 2008-01-16 | Microfluidic device |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB0700822A GB2445738A (en) | 2007-01-16 | 2007-01-16 | Microfluidic device |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| GB0700822D0 GB0700822D0 (en) | 2007-02-21 |
| GB2445738A true GB2445738A (en) | 2008-07-23 |
Family
ID=37810038
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB0700822A Withdrawn GB2445738A (en) | 2007-01-16 | 2007-01-16 | Microfluidic device |
Country Status (6)
| Country | Link |
|---|---|
| US (1) | US20100175999A1 (enExample) |
| EP (1) | EP2114570B1 (enExample) |
| JP (1) | JP5579443B2 (enExample) |
| CN (1) | CN101674888B (enExample) |
| GB (1) | GB2445738A (enExample) |
| WO (1) | WO2008087405A1 (enExample) |
Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| RU2280769C2 (ru) * | 2000-10-24 | 2006-07-27 | Ханс Енсен Лубрикаторс А/С | Дозирующая система |
| WO2012028595A1 (de) * | 2010-09-01 | 2012-03-08 | Boehringer Ingelheim Microparts Gmbh | Verfahren zum herstellen einer mikrofluidischen vorrichtung sowie diesbezügliche laminiereinrichtungen |
| WO2013102071A1 (en) * | 2011-12-30 | 2013-07-04 | Abbott Molecular, Inc. | Chemical reaction vessels |
| US10704537B2 (en) | 2014-04-11 | 2020-07-07 | President And Fellows Of Harvard College | High throughput fabrication of soft machines |
Families Citing this family (32)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP1733226B1 (en) | 2004-04-07 | 2015-07-29 | Levine, Robert Aaron | Disposable chamber for analyzing biologic fluids |
| US8715446B2 (en) * | 2004-10-13 | 2014-05-06 | Rheonix, Inc. | Latent solvent-based microfluidic apparatus, methods, and applications |
| US7731901B2 (en) | 2005-10-19 | 2010-06-08 | Abbott Laboratories | Apparatus and method for performing counts within a biologic fluid sample |
| GB2445739A (en) | 2007-01-16 | 2008-07-23 | Lab901 Ltd | Polymeric laminates containing heat seals |
| ES2352581T3 (es) * | 2008-06-02 | 2011-02-21 | Boehringer Ingelheim Microparts Gmbh | Estructura de lámina microfluídica para dosificar líquidos. |
| JP2011030522A (ja) * | 2009-08-04 | 2011-02-17 | Aida Engineering Ltd | マイクロ流体デバイス |
| CN102762289B (zh) | 2009-12-18 | 2016-08-03 | 艾博特健康公司 | 生物流体分析卡盒 |
| US8720036B2 (en) | 2010-03-09 | 2014-05-13 | Netbio, Inc. | Unitary biochip providing sample-in to results-out processing and methods of manufacture |
| EP3690433B9 (en) * | 2010-03-09 | 2022-12-21 | ANDE Corporation | Biochip with reagent storage |
| CN101823686B (zh) * | 2010-04-21 | 2012-07-04 | 大连理工大学 | 一种热塑性聚合物多层微流控芯片封合方法 |
| JP5582049B2 (ja) * | 2010-05-31 | 2014-09-03 | 横河電機株式会社 | 化学処理用カートリッジシステム |
| CN103282123B (zh) | 2010-12-30 | 2015-05-06 | 艾博特健康公司 | 带有样品处理区和分析室区的生物液体分析卡式盒 |
| US20130137144A1 (en) * | 2011-06-08 | 2013-05-30 | Bio-Rad Laboratories, Inc. LSG - GXD Division | Thermal block with built-in thermoelectric elements |
| US8797527B2 (en) | 2011-08-24 | 2014-08-05 | Abbott Point Of Care, Inc. | Biologic fluid sample analysis cartridge |
| JP6033959B2 (ja) * | 2013-01-09 | 2016-11-30 | テカン・トレーディング・アクチェンゲゼルシャフトＴＥＣＡＮ Ｔｒａｄｉｎｇ ＡＧ | マイクロ流体システム用使い捨てカートリッジ |
| CN104955575A (zh) | 2013-01-24 | 2015-09-30 | 沙特基础全球技术有限公司 | 由聚酯-聚碳酸酯制成的微流体装置和微孔 |
| EP2948252A1 (en) | 2013-01-24 | 2015-12-02 | SABIC Global Technologies B.V. | Microwell plate made from a polyester-polycarbonate |
| WO2014116955A1 (en) | 2013-01-24 | 2014-07-31 | Sabic Innovative Plastics Ip B.V. | Microwell plate made from a polyester-polycarbonate |
| JP6012518B2 (ja) * | 2013-03-21 | 2016-10-25 | 株式会社日立ハイテクノロジーズ | 生化学カートリッジ用温調機構、温調ブロック及び生化学処理装置 |
| CN104607256A (zh) * | 2014-12-31 | 2015-05-13 | 北京同方生物芯片技术有限公司 | 等离子体辅助热压键合微流控芯片及其制备方法 |
| US11285478B2 (en) | 2016-04-04 | 2022-03-29 | Combinati Incorporated | Microfluidic siphoning array for nucleic acid quantification |
| US9845499B2 (en) * | 2016-04-04 | 2017-12-19 | Combinati Incorporated | Microfluidic siphoning array for nucleic acid quantification |
| CN115044655A (zh) | 2016-11-17 | 2022-09-13 | 康比纳提公司 | 用于核酸分析和定量的方法和系统 |
| EP3384987A3 (en) * | 2017-04-03 | 2018-10-24 | CSEM Centre Suisse d'Electronique et de Microtechnique SA - Recherche et Développement | Vessel for performing electrochemical measurements and method for manufacturing such vessel |
| EP3669179B1 (en) | 2017-08-17 | 2023-07-19 | Abbott Point Of Care Inc | Systems for performing optical and electrochemical assays |
| CN110869745B (zh) | 2017-08-17 | 2023-08-11 | 雅培医护站股份有限公司 | 用于执行光学测定的设备、系统和方法 |
| CN107739706B (zh) * | 2017-09-26 | 2020-04-14 | 南京岚煜生物科技有限公司 | 主动控制流路的多通量微流控核酸检测芯片及其使用方法 |
| DE102018217907B3 (de) * | 2018-10-19 | 2019-12-19 | SpinDiag GmbH | Probenbehälter |
| CA3122712A1 (en) | 2018-12-10 | 2020-06-18 | Combinati Incorporated | Microfluidic array for sample digitization |
| CN112569881B (zh) * | 2020-07-24 | 2021-07-20 | 苏州恒瑞宏远医疗科技有限公司 | 一种反应装置及其加工方法 |
| DE102020202767B3 (de) * | 2020-03-04 | 2021-05-27 | Hahn-Schickard-Gesellschaft für angewandte Forschung e.V. | Herstellung eines Verbunds aus Polymersubstraten und gesiegelte mikrofluidische Kartusche |
| CN116368213A (zh) | 2020-09-28 | 2023-06-30 | 康比纳蒂股份有限公司 | 用于样品处理的装置和方法 |
Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2003220330A (ja) * | 2002-01-31 | 2003-08-05 | Asahi Kasei Corp | 透明ポリマーチップ |
| US20060272716A1 (en) * | 2005-05-12 | 2006-12-07 | University Of Washington | Method of adhesiveless lamination of polymer films into microfluidic networks with high dimensional fidelity |
Family Cites Families (24)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4333968A (en) * | 1980-01-25 | 1982-06-08 | Mobil Oil Corporation | Thermoplastic packaging films with improved heat-seal characteristics |
| WO1994026414A1 (en) * | 1993-05-17 | 1994-11-24 | Syntex (U.S.A.) Inc. | Reaction container for specific binding assays and method for its use |
| US5658413A (en) * | 1994-10-19 | 1997-08-19 | Hewlett-Packard Company | Miniaturized planar columns in novel support media for liquid phase analysis |
| US5500071A (en) * | 1994-10-19 | 1996-03-19 | Hewlett-Packard Company | Miniaturized planar columns in novel support media for liquid phase analysis |
| US5525405A (en) * | 1994-12-14 | 1996-06-11 | E. I. Du Pont De Nemours And Company | Adhesiveless aromatic polyimide laminate |
| JP3839524B2 (ja) * | 1995-06-07 | 2006-11-01 | アジレント・テクノロジーズ・インク | 小型化全分析システム |
| US5932799A (en) * | 1997-07-21 | 1999-08-03 | Ysi Incorporated | Microfluidic analyzer module |
| US6375871B1 (en) * | 1998-06-18 | 2002-04-23 | 3M Innovative Properties Company | Methods of manufacturing microfluidic articles |
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- 2008-01-16 US US12/523,500 patent/US20100175999A1/en not_active Abandoned
- 2008-01-16 CN CN2008800065615A patent/CN101674888B/zh active Active
- 2008-01-16 JP JP2009545993A patent/JP5579443B2/ja active Active
- 2008-01-16 EP EP08701821.4A patent/EP2114570B1/en active Active
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| US20060272716A1 (en) * | 2005-05-12 | 2006-12-07 | University Of Washington | Method of adhesiveless lamination of polymer films into microfluidic networks with high dimensional fidelity |
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| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| RU2280769C2 (ru) * | 2000-10-24 | 2006-07-27 | Ханс Енсен Лубрикаторс А/С | Дозирующая система |
| WO2012028595A1 (de) * | 2010-09-01 | 2012-03-08 | Boehringer Ingelheim Microparts Gmbh | Verfahren zum herstellen einer mikrofluidischen vorrichtung sowie diesbezügliche laminiereinrichtungen |
| US9522520B2 (en) | 2010-09-01 | 2016-12-20 | Boehringer Ingelheim Microparts Gmbh | Process for producing a microfluidic apparatus and related laminating devices |
| WO2013102071A1 (en) * | 2011-12-30 | 2013-07-04 | Abbott Molecular, Inc. | Chemical reaction vessels |
| US10704537B2 (en) | 2014-04-11 | 2020-07-07 | President And Fellows Of Harvard College | High throughput fabrication of soft machines |
Also Published As
| Publication number | Publication date |
|---|---|
| JP5579443B2 (ja) | 2014-08-27 |
| EP2114570A1 (en) | 2009-11-11 |
| CN101674888A (zh) | 2010-03-17 |
| GB0700822D0 (en) | 2007-02-21 |
| CN101674888B (zh) | 2012-06-13 |
| EP2114570B1 (en) | 2013-06-05 |
| US20100175999A1 (en) | 2010-07-15 |
| JP2010515924A (ja) | 2010-05-13 |
| WO2008087405A1 (en) | 2008-07-24 |
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