JP5517454B2 - Ｃ型肝炎感染の治療及び予防のための方法及び医薬組成物 - Google Patents

Ｃ型肝炎感染の治療及び予防のための方法及び医薬組成物 Download PDF

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JP5517454B2
JP5517454B2 JP2008533792A JP2008533792A JP5517454B2 JP 5517454 B2 JP5517454 B2 JP 5517454B2 JP 2008533792 A JP2008533792 A JP 2008533792A JP 2008533792 A JP2008533792 A JP 2008533792A JP 5517454 B2 JP5517454 B2 JP 5517454B2
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acid
cyclosporine
agent
hcv
compound
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JP2009510129A (ja
JP2009510129A5 (cg-RX-API-DMAC7.html
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レンウィクク ホウクク ダビド
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スシネキス インク
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/12—Cyclic peptides, e.g. bacitracins; Polymyxins; Gramicidins S, C; Tyrocidins A, B or C
    • A61K38/13—Cyclosporins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/19—Cytokines; Lymphokines; Interferons
    • A61K38/21—Interferons [IFN]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2300/00—Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Immunology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Epidemiology (AREA)
  • Virology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Zoology (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Molecular Biology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Peptides Or Proteins (AREA)
JP2008533792A 2005-09-30 2006-10-02 Ｃ型肝炎感染の治療及び予防のための方法及び医薬組成物 Expired - Fee Related JP5517454B2 (ja)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US72267905P 2005-09-30 2005-09-30
US60/722,679 2005-09-30
US78754906P 2006-03-29 2006-03-29
US60/787,549 2006-03-29
PCT/US2006/038823 WO2007041632A2 (en) 2005-09-30 2006-10-02 Methods and pharmaceutical compositions for the treatment and prevention of hepatitis c infection

Publications (3)

Publication Number Publication Date
JP2009510129A JP2009510129A (ja) 2009-03-12
JP2009510129A5 JP2009510129A5 (cg-RX-API-DMAC7.html) 2009-11-19
JP5517454B2 true JP5517454B2 (ja) 2014-06-11

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JP2008533792A Expired - Fee Related JP5517454B2 (ja) 2005-09-30 2006-10-02 Ｃ型肝炎感染の治療及び予防のための方法及び医薬組成物

Country Status (13)

Country Link
US (1) US7754685B2 (cg-RX-API-DMAC7.html)
EP (1) EP1933859A2 (cg-RX-API-DMAC7.html)
JP (1) JP5517454B2 (cg-RX-API-DMAC7.html)
KR (1) KR20080059270A (cg-RX-API-DMAC7.html)
CN (1) CN105169369B (cg-RX-API-DMAC7.html)
AU (1) AU2006299426B2 (cg-RX-API-DMAC7.html)
BR (1) BRPI0616476A2 (cg-RX-API-DMAC7.html)
CA (1) CA2623865A1 (cg-RX-API-DMAC7.html)
IL (1) IL190478A0 (cg-RX-API-DMAC7.html)
NZ (1) NZ567262A (cg-RX-API-DMAC7.html)
RU (1) RU2440822C2 (cg-RX-API-DMAC7.html)
WO (1) WO2007041632A2 (cg-RX-API-DMAC7.html)
ZA (1) ZA200803493B (cg-RX-API-DMAC7.html)

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US7196161B2 (en) * 2004-10-01 2007-03-27 Scynexis Inc. 3-ether and 3-thioether substituted cyclosporin derivatives for the treatment and prevention of hepatitis C infection
DK1802650T3 (da) * 2004-10-01 2012-02-06 Scynexis Inc 3-ether- og 3-thioether-substituerede cyklosporinderivater til behandling og forebyggelse af hepatitis C-infektion
US8329658B2 (en) 2005-09-30 2012-12-11 Scynexis, Inc. Arylalkyl and heteroarylalkyl derivatives of cyclosporine A for the treatment and prevention of viral infection
US7754685B2 (en) 2005-09-30 2010-07-13 Scynexis, Inc. Methods and pharmaceutical compositions for the treatment and prevention of hepatitis C infection
DK2023918T3 (da) 2006-05-19 2011-04-26 Scynexis Inc Cyclosporiner til behandlingen og forebyggelse af okulære lidelser
JP2009539292A (ja) * 2006-06-02 2009-11-12 ぺリション、クロード、アニー 活性電子の管理
CA2659461A1 (en) * 2006-08-25 2008-02-28 Wyeth Identification and characterization of hcv replicon variants with reduced susceptibility to hcv-796, and methods related thereto
WO2008069917A2 (en) 2006-11-20 2008-06-12 Scynexis, Inc. Novel cyclic peptides
WO2008127613A1 (en) * 2007-04-11 2008-10-23 Scynexis, Inc. New pharmaceutical compositions
JP2010526143A (ja) 2007-05-04 2010-07-29 バーテックス ファーマシューティカルズ インコーポレイテッド Ｈｃｖ感染の処置のための併用療法
EP2116602A1 (en) 2008-05-07 2009-11-11 Institut Gustave Roussy Combination products for treating cancer
WO2010002428A2 (en) 2008-06-06 2010-01-07 Scynexis, Inc. Novel macrocyclic peptides
US20090306033A1 (en) * 2008-06-06 2009-12-10 Keqiang Li Novel cyclic peptides
KR101068160B1 (ko) * 2008-12-30 2011-09-27 건국대학교 산학협력단 Ｃ형 간염 바이러스 ｒｎａ핵산 중합효소의 활성을 저해하는 신규 플라보놀 유도체
JP5780969B2 (ja) 2008-12-31 2015-09-16 サイネクシス，インコーポレーテッド シクロスポリンａの誘導体
MX2011007194A (es) * 2009-01-07 2013-07-12 Scynexis Inc Combinacion de un derivado ciclosporina y nucleosidos para tratar virus de hepatitis c (vhc).
EP2483406A2 (en) 2009-09-30 2012-08-08 President and Fellows of Harvard College Methods for modulation of autophagy through the modulation of autophagy-inhibiting gene products
JP2014520835A (ja) 2011-07-15 2014-08-25 ビーエーエスエフ ソシエタス・ヨーロピア 動物有害生物を駆除するための置換３−ピリジルチアゾール化合物および誘導体ｉを使用した有害生物防除方法
RU2639388C1 (ru) * 2016-10-11 2017-12-21 Федеральное государственное бюджетное учреждение "Государственный научный центр "Институт иммунологии" Федерального медико-биологического агентства России Композиция для терапии вирусного гепатита С
WO2020037530A1 (en) 2018-08-22 2020-02-27 Waterstone Pharmaceuticals (Wuhan) Co., Ltd. Crystalline form of compound and uses thereof in medicine
CN114245744A (zh) * 2020-04-15 2022-03-25 睿诺医疗科技（上海）有限公司 器官损伤的预防和治疗

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US5948884A (en) 1995-07-17 1999-09-07 C-Chem Ag Cyclosporin derivatives with anti-HIV effect
FR2757522B1 (fr) 1996-12-24 1999-01-29 Rhone Poulenc Rorer Sa Derives de cyclosporine, leur preparation et les compositions pharmaceutiques qui les contiennent
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KR20070089954A (ko) 2004-12-23 2007-09-04 노파르티스 아게 플라비비리대 치료용 화합물
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DK2023918T3 (da) 2006-05-19 2011-04-26 Scynexis Inc Cyclosporiner til behandlingen og forebyggelse af okulære lidelser
WO2008069917A2 (en) 2006-11-20 2008-06-12 Scynexis, Inc. Novel cyclic peptides
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Also Published As

Publication number Publication date
AU2006299426B2 (en) 2012-07-26
JP2009510129A (ja) 2009-03-12
WO2007041632A2 (en) 2007-04-12
RU2008117157A (ru) 2009-11-10
AU2006299426A1 (en) 2007-04-12
US7754685B2 (en) 2010-07-13
IL190478A0 (en) 2008-11-03
WO2007041632A3 (en) 2007-12-13
CA2623865A1 (en) 2007-04-12
US20070173440A1 (en) 2007-07-26
NZ567262A (en) 2011-12-22
RU2440822C2 (ru) 2012-01-27
CN105169369A (zh) 2015-12-23
CN105169369B (zh) 2019-10-18
EP1933859A2 (en) 2008-06-25
KR20080059270A (ko) 2008-06-26
BRPI0616476A2 (pt) 2011-06-21
ZA200803493B (en) 2009-12-30

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