JP2009510129A5 - - Google Patents

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Publication number
JP2009510129A5
JP2009510129A5 JP2008533792A JP2008533792A JP2009510129A5 JP 2009510129 A5 JP2009510129 A5 JP 2009510129A5 JP 2008533792 A JP2008533792 A JP 2008533792A JP 2008533792 A JP2008533792 A JP 2008533792A JP 2009510129 A5 JP2009510129 A5 JP 2009510129A5
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JP
Japan
Prior art keywords
pharmaceutical composition
composition according
agent
modulator
solvate
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Application number
JP2008533792A
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English (en)
Japanese (ja)
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JP2009510129A (ja
JP5517454B2 (ja
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Priority claimed from PCT/US2006/038823 external-priority patent/WO2007041632A2/en
Publication of JP2009510129A publication Critical patent/JP2009510129A/ja
Publication of JP2009510129A5 publication Critical patent/JP2009510129A5/ja
Application granted granted Critical
Publication of JP5517454B2 publication Critical patent/JP5517454B2/ja
Expired - Fee Related legal-status Critical Current
Anticipated expiration legal-status Critical

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JP2008533792A 2005-09-30 2006-10-02 C型肝炎感染の治療及び予防のための方法及び医薬組成物 Expired - Fee Related JP5517454B2 (ja)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US72267905P 2005-09-30 2005-09-30
US60/722,679 2005-09-30
US78754906P 2006-03-29 2006-03-29
US60/787,549 2006-03-29
PCT/US2006/038823 WO2007041632A2 (en) 2005-09-30 2006-10-02 Methods and pharmaceutical compositions for the treatment and prevention of hepatitis c infection

Publications (3)

Publication Number Publication Date
JP2009510129A JP2009510129A (ja) 2009-03-12
JP2009510129A5 true JP2009510129A5 (cg-RX-API-DMAC7.html) 2009-11-19
JP5517454B2 JP5517454B2 (ja) 2014-06-11

Family

ID=37906852

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2008533792A Expired - Fee Related JP5517454B2 (ja) 2005-09-30 2006-10-02 C型肝炎感染の治療及び予防のための方法及び医薬組成物

Country Status (13)

Country Link
US (1) US7754685B2 (cg-RX-API-DMAC7.html)
EP (1) EP1933859A2 (cg-RX-API-DMAC7.html)
JP (1) JP5517454B2 (cg-RX-API-DMAC7.html)
KR (1) KR20080059270A (cg-RX-API-DMAC7.html)
CN (1) CN105169369B (cg-RX-API-DMAC7.html)
AU (1) AU2006299426B2 (cg-RX-API-DMAC7.html)
BR (1) BRPI0616476A2 (cg-RX-API-DMAC7.html)
CA (1) CA2623865A1 (cg-RX-API-DMAC7.html)
IL (1) IL190478A0 (cg-RX-API-DMAC7.html)
NZ (1) NZ567262A (cg-RX-API-DMAC7.html)
RU (1) RU2440822C2 (cg-RX-API-DMAC7.html)
WO (1) WO2007041632A2 (cg-RX-API-DMAC7.html)
ZA (1) ZA200803493B (cg-RX-API-DMAC7.html)

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US7196161B2 (en) * 2004-10-01 2007-03-27 Scynexis Inc. 3-ether and 3-thioether substituted cyclosporin derivatives for the treatment and prevention of hepatitis C infection
DK1802650T3 (da) * 2004-10-01 2012-02-06 Scynexis Inc 3-ether- og 3-thioether-substituerede cyklosporinderivater til behandling og forebyggelse af hepatitis C-infektion
US8329658B2 (en) 2005-09-30 2012-12-11 Scynexis, Inc. Arylalkyl and heteroarylalkyl derivatives of cyclosporine A for the treatment and prevention of viral infection
US7754685B2 (en) 2005-09-30 2010-07-13 Scynexis, Inc. Methods and pharmaceutical compositions for the treatment and prevention of hepatitis C infection
DK2023918T3 (da) 2006-05-19 2011-04-26 Scynexis Inc Cyclosporiner til behandlingen og forebyggelse af okulære lidelser
JP2009539292A (ja) * 2006-06-02 2009-11-12 ぺリション、クロード、アニー 活性電子の管理
CA2659461A1 (en) * 2006-08-25 2008-02-28 Wyeth Identification and characterization of hcv replicon variants with reduced susceptibility to hcv-796, and methods related thereto
WO2008069917A2 (en) 2006-11-20 2008-06-12 Scynexis, Inc. Novel cyclic peptides
WO2008127613A1 (en) * 2007-04-11 2008-10-23 Scynexis, Inc. New pharmaceutical compositions
JP2010526143A (ja) 2007-05-04 2010-07-29 バーテックス ファーマシューティカルズ インコーポレイテッド Hcv感染の処置のための併用療法
EP2116602A1 (en) 2008-05-07 2009-11-11 Institut Gustave Roussy Combination products for treating cancer
WO2010002428A2 (en) 2008-06-06 2010-01-07 Scynexis, Inc. Novel macrocyclic peptides
US20090306033A1 (en) * 2008-06-06 2009-12-10 Keqiang Li Novel cyclic peptides
KR101068160B1 (ko) * 2008-12-30 2011-09-27 건국대학교 산학협력단 C형 간염 바이러스 rna핵산 중합효소의 활성을 저해하는 신규 플라보놀 유도체
JP5780969B2 (ja) 2008-12-31 2015-09-16 サイネクシス,インコーポレーテッド シクロスポリンaの誘導体
MX2011007194A (es) * 2009-01-07 2013-07-12 Scynexis Inc Combinacion de un derivado ciclosporina y nucleosidos para tratar virus de hepatitis c (vhc).
EP2483406A2 (en) 2009-09-30 2012-08-08 President and Fellows of Harvard College Methods for modulation of autophagy through the modulation of autophagy-inhibiting gene products
JP2014520835A (ja) 2011-07-15 2014-08-25 ビーエーエスエフ ソシエタス・ヨーロピア 動物有害生物を駆除するための置換3−ピリジルチアゾール化合物および誘導体iを使用した有害生物防除方法
RU2639388C1 (ru) * 2016-10-11 2017-12-21 Федеральное государственное бюджетное учреждение "Государственный научный центр "Институт иммунологии" Федерального медико-биологического агентства России Композиция для терапии вирусного гепатита С
WO2020037530A1 (en) 2018-08-22 2020-02-27 Waterstone Pharmaceuticals (Wuhan) Co., Ltd. Crystalline form of compound and uses thereof in medicine
CN114245744A (zh) * 2020-04-15 2022-03-25 睿诺医疗科技(上海)有限公司 器官损伤的预防和治疗

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CA2159219A1 (en) 1993-03-31 1994-10-13 Minoru Maeda Cholestasis ameliorant
US5846964A (en) 1993-07-19 1998-12-08 Tokyo Tanabe Company Limited Hepatitis C virus proliferation inhibitor
US5948884A (en) 1995-07-17 1999-09-07 C-Chem Ag Cyclosporin derivatives with anti-HIV effect
FR2757522B1 (fr) 1996-12-24 1999-01-29 Rhone Poulenc Rorer Sa Derives de cyclosporine, leur preparation et les compositions pharmaceutiques qui les contiennent
FR2757521B1 (fr) 1996-12-24 1999-01-29 Rhone Poulenc Rorer Sa Nouveaux derives de cyclosporine, leur preparation et les compositions pharmaceutiques qui les contiennent
FR2757520B1 (fr) 1996-12-24 1999-01-29 Rhone Poulenc Rorer Sa Derive de cyclosporine, sa preparation et les compositions pharmaceutiques qui le contiennent
FR2762843B1 (fr) 1997-04-30 1999-12-10 Rhone Poulenc Rorer Sa Nouveaux derives de cyclosporine, leur preparation et les compositions pharmaceutiques qui les contiennent
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HUP0102833A3 (en) * 1998-06-12 2002-03-28 Chem Ag C Cyclosporins, process for preparation thereof and their use
FR2780061B1 (fr) 1998-06-22 2001-09-07 Rhone Poulenc Rorer Sa Nouveau procede de preparation de derives de cyclosporine
WO2000001715A1 (fr) 1998-07-01 2000-01-13 Debiopharm S.A. Nouvelle cyclosporine ayant un profil d'activite ameliore
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CN1678326A (zh) 2002-06-28 2005-10-05 埃迪尼克斯(开曼)有限公司 用于治疗黄病毒感染的2'-c-甲基-3'-o-l-缬氨酸酯核糖呋喃基胞苷
US20050009877A1 (en) 2003-05-15 2005-01-13 Henry Lu Methods of identifying HCV NS5B polymerase inhibitors and their uses
AR044694A1 (es) * 2003-06-17 2005-09-21 Schering Corp Proceso y compuestos intermedios para la preparacion de (1r, 2s,5s) - 3 azabiciclo [3,1,0] hexano-2- carboxamida, n- [3- amino-1- (ciclobutilmetil) - 2, 3 - dioxopropil] -3- [ (2s) - 2 - [[ [ 1,1- dimetiletil] amino] carbonilamino] -3,3-dimetil -1- oxobutil]-6,6 dimetilo
GB0320638D0 (en) 2003-09-03 2003-10-01 Novartis Ag Organic compounds
CA2573207C (en) 2004-07-14 2013-04-16 Novartis Ag Use of a combination of cyclosporin and pegylated interferons for treating hepatitis c (hcv)
US20060025267A1 (en) 2004-07-29 2006-02-02 Mircea Gradu Differential with torque vectoring capabilities
NZ554412A (en) 2004-10-01 2011-01-28 Debiopharm Sa Use of [D-MeAla]3-[EtVal]4-cyclosporin for the treatment of hepatitis C infection and pharmaceutical composition comprising said [D-MeAla]3-[EtVal]4-cyclosporin
DK1802650T3 (da) * 2004-10-01 2012-02-06 Scynexis Inc 3-ether- og 3-thioether-substituerede cyklosporinderivater til behandling og forebyggelse af hepatitis C-infektion
US7196161B2 (en) 2004-10-01 2007-03-27 Scynexis Inc. 3-ether and 3-thioether substituted cyclosporin derivatives for the treatment and prevention of hepatitis C infection
CN101076350A (zh) 2004-12-23 2007-11-21 诺瓦提斯公司 用于hcv治疗的组合物
KR20070089954A (ko) 2004-12-23 2007-09-04 노파르티스 아게 플라비비리대 치료용 화합물
US7473688B2 (en) 2005-09-13 2009-01-06 Bristol-Myers Squibb Company Indolobenzazepine HCV NS5B inhibitors
US8329658B2 (en) 2005-09-30 2012-12-11 Scynexis, Inc. Arylalkyl and heteroarylalkyl derivatives of cyclosporine A for the treatment and prevention of viral infection
US7754685B2 (en) 2005-09-30 2010-07-13 Scynexis, Inc. Methods and pharmaceutical compositions for the treatment and prevention of hepatitis C infection
DK2023918T3 (da) 2006-05-19 2011-04-26 Scynexis Inc Cyclosporiner til behandlingen og forebyggelse af okulære lidelser
WO2008069917A2 (en) 2006-11-20 2008-06-12 Scynexis, Inc. Novel cyclic peptides
WO2008127613A1 (en) 2007-04-11 2008-10-23 Scynexis, Inc. New pharmaceutical compositions
WO2008143996A1 (en) 2007-05-18 2008-11-27 Scynexis, Inc. New chemical processes

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