JP5513126B2 - 肝疾患を予防および/または制御するための、キサントフモールまたはイソキサントフモールの活性物質としての使用 - Google Patents

肝疾患を予防および/または制御するための、キサントフモールまたはイソキサントフモールの活性物質としての使用 Download PDF

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JP5513126B2
JP5513126B2 JP2009541912A JP2009541912A JP5513126B2 JP 5513126 B2 JP5513126 B2 JP 5513126B2 JP 2009541912 A JP2009541912 A JP 2009541912A JP 2009541912 A JP2009541912 A JP 2009541912A JP 5513126 B2 JP5513126 B2 JP 5513126B2
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xanthohumol
isoxanthohumol
active substance
liver
weight
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JP2010513360A5 (cg-RX-API-DMAC7.html
JP2010513360A (ja
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ヘレルブランド、クラウス
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フラキサン ゲーエムベーハー ウント コー. カーゲー
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/335Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/35Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
    • A61K31/352Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom condensed with carbocyclic rings, e.g. methantheline 
    • A61K31/3533,4-Dihydrobenzopyrans, e.g. chroman, catechin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/12Ketones
    • A61K31/121Ketones acyclic
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/12Ketones
    • A61K31/122Ketones having the oxygen directly attached to a ring, e.g. quinones, vitamin K1, anthralin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/348Cannabaceae
    • A61K36/3486Humulus
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/16Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/04Anorexiants; Antiobesity agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/08Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • A61P31/14Antivirals for RNA viruses
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • A61P31/20Antivirals for DNA viruses
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P39/00General protective or antinoxious agents
    • A61P39/06Free radical scavengers or antioxidants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Natural Medicines & Medicinal Plants (AREA)
  • Virology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Diabetes (AREA)
  • Biotechnology (AREA)
  • Oncology (AREA)
  • Obesity (AREA)
  • Communicable Diseases (AREA)
  • Hematology (AREA)
  • Alternative & Traditional Medicine (AREA)
  • Molecular Biology (AREA)
  • Mycology (AREA)
  • Microbiology (AREA)
  • Medical Informatics (AREA)
  • Botany (AREA)
  • Toxicology (AREA)
  • Child & Adolescent Psychology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Endocrinology (AREA)
  • Emergency Medicine (AREA)
  • Biochemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Coloring Foods And Improving Nutritive Qualities (AREA)
JP2009541912A 2006-12-22 2007-12-21 肝疾患を予防および/または制御するための、キサントフモールまたはイソキサントフモールの活性物質としての使用 Expired - Fee Related JP5513126B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
DE102006062264A DE102006062264A1 (de) 2006-12-22 2006-12-22 Verwendung von Xanthohumol zur Vorbeugung und/oder Bekämpfung von Lebererkrankungen
DE102006062264.2 2006-12-22
PCT/EP2007/011358 WO2008077618A1 (de) 2006-12-22 2007-12-21 Verwendung von xanthohumol bzw. isoxanthohumol als wirkstoff zur vorbeugung und/oder bekämpfung von lebererkrankungen

Publications (3)

Publication Number Publication Date
JP2010513360A JP2010513360A (ja) 2010-04-30
JP2010513360A5 JP2010513360A5 (cg-RX-API-DMAC7.html) 2011-01-13
JP5513126B2 true JP5513126B2 (ja) 2014-06-04

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JP2009541912A Expired - Fee Related JP5513126B2 (ja) 2006-12-22 2007-12-21 肝疾患を予防および/または制御するための、キサントフモールまたはイソキサントフモールの活性物質としての使用

Country Status (7)

Country Link
US (1) US20100029757A1 (cg-RX-API-DMAC7.html)
EP (1) EP2120906B1 (cg-RX-API-DMAC7.html)
JP (1) JP5513126B2 (cg-RX-API-DMAC7.html)
CA (1) CA2672155C (cg-RX-API-DMAC7.html)
DE (1) DE102006062264A1 (cg-RX-API-DMAC7.html)
RU (1) RU2454996C2 (cg-RX-API-DMAC7.html)
WO (1) WO2008077618A1 (cg-RX-API-DMAC7.html)

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* Cited by examiner, † Cited by third party
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US10722575B2 (en) 2009-11-26 2020-07-28 Genfit Use of 1,3-diphenylprop-2-en-1-one derivatives for treating liver disorders
EP2641596B1 (en) * 2009-11-26 2018-05-02 Genfit Use of 1,3-diphenylprop-2-en-1-one derivatives for treating liver disorders
US9221751B2 (en) 2009-11-26 2015-12-29 Genfit Use of 1,3-diphenylprop-2-en-1-one derivatives for treating liver disorders
US9358185B2 (en) 2012-06-18 2016-06-07 3M Innovative Properties Company Powder composition for air polishing the surface of hard dental tissue
ES2822575T3 (es) * 2012-07-26 2021-05-04 Arcaini Antonio Usos de composiciones que contienen un extracto tostado y xantohumol
EP2742898A1 (en) 2012-12-17 2014-06-18 3M Innovative Properties Company Powder jet device for dispensing a dental material
US9662180B2 (en) 2012-12-17 2017-05-30 3M Innovative Properties Company Device for dispensing a dental material with locking mechanism
EP2742897A1 (en) 2012-12-17 2014-06-18 3M Innovative Properties Company Nozzle head, hand piece and powder jet device for applying a dental material
JP2018519342A (ja) * 2015-07-02 2018-07-19 フラクサン ゲーエムベーハー ウント コー. カーゲー ホップに基づく物質およびその物質の使用
KR20190099481A (ko) * 2016-12-20 2019-08-27 산토리 홀딩스 가부시키가이샤 이소잔토휴몰을 함유하는 지질 대사 촉진용 조성물
FI3651804T3 (en) 2017-07-11 2023-10-04 Aquanova Ag CELL BILISATE CONTAINING CURCUMINE, BOSWELLIA AND XANTHOHUMOL
FI3820527T3 (en) 2018-07-11 2023-09-28 Aquanova Ag XANTHOHUMOL CELL BILISATE
EP3820527B1 (de) * 2018-07-11 2023-08-23 Aquanova AG Xanthohumol-solubilisat
WO2020031957A1 (ja) * 2018-08-10 2020-02-13 サントリーホールディングス株式会社 腸内環境改善用組成物及び腸内細菌叢改善方法
SG11202100265XA (en) * 2018-08-10 2021-02-25 Suntory Holdings Ltd Composition for promoting uric acid excretion, composition for inhibiting urat1 and composition for lowering blood uric acid level
AU2019317043A1 (en) * 2018-08-10 2021-02-04 Suntory Holdings Limited Composition and method for suppressing increase in blood glucose level
SG11202100258PA (en) * 2018-08-10 2021-02-25 Suntory Holdings Ltd Agent for suppressing microbial growth, method for preventing microbial contamination, and beverage
EP4291307A4 (en) * 2021-02-09 2025-01-22 Oregon State University Xanthohumol derivatives and methods for making and using
CA3225379A1 (en) * 2021-07-09 2023-01-12 Devrim ARAN Prenylated chalcone and flavonoid compositions for use in treating cancer

Family Cites Families (14)

* Cited by examiner, † Cited by third party
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JPH07285856A (ja) 1994-04-21 1995-10-31 Hoechst Japan Ltd 骨粗鬆症治療剤
JP2000504035A (ja) * 1996-08-30 2000-04-04 エヌピーエス パーマシューティカルズ インク. イソ吉草酸cns抑制剤による痙縮、痙攣の治療
WO2001003681A2 (en) 1999-07-08 2001-01-18 Prendergast Patrick T Use of flavones, coumarins and related compounds to treat infections
JP3293601B2 (ja) * 1999-09-03 2002-06-17 松下電器産業株式会社 管球およびその製造方法
EP1666051A3 (en) * 2000-04-10 2009-10-07 Takara Bio, Inc. Remedies
US20040156950A1 (en) * 2001-04-05 2004-08-12 Green Martin Richard Use of hop components in foods
JPWO2003006037A1 (ja) * 2001-07-13 2004-10-28 タカラバイオ株式会社 治療剤
DE10308864B4 (de) 2003-02-28 2007-03-01 Paulaner Brauerei Gmbh & Co. Kg Neues Brauverfahren, damit gebrautes Bier und dessen Verwendung
EP1543834A1 (en) 2003-12-16 2005-06-22 Biodynamics Production of hop extracts having oestrogenic and antiproliferative bioactivity
WO2006099015A2 (en) 2005-03-09 2006-09-21 Cardax Pharmaceuticals, Inc. Carotenoids, carotenoid analogs, or carotenoid derivatives for the treatment of proliferative disorders
JP2006306800A (ja) * 2005-04-28 2006-11-09 Kirin Brewery Co Ltd ファルネソイドx受容体活性化剤
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Also Published As

Publication number Publication date
RU2454996C2 (ru) 2012-07-10
EP2120906B1 (de) 2015-04-22
JP2010513360A (ja) 2010-04-30
DE102006062264A1 (de) 2008-06-26
CA2672155A1 (en) 2008-07-03
EP2120906A1 (de) 2009-11-25
CA2672155C (en) 2013-10-01
RU2009128213A (ru) 2011-01-27
US20100029757A1 (en) 2010-02-04
WO2008077618A1 (de) 2008-07-03

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